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There are 2501 results for: content related to: Hypoxanthine guanine phosphoribosyltransferase activity is related to 6-thioguanine nucleotide concentrations and thiopurine-induced leukopenia in the treatment of inflammatory bowel disease

  1. You have free access to this content
    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Version of Record online : 20 MAR 2014, DOI: 10.1111/bcp.12226

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    Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 43, Issue 8, April 2016, Pages: 863–883, W. Moon and E. V. Loftus Jr

    Version of Record online : 14 FEB 2016, DOI: 10.1111/apt.13559

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    Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 35, Issue 1, January 2012, Pages: 15–36, L. Chouchana, C. Narjoz, P. Beaune, M.-A. Loriot and X. Roblin

    Version of Record online : 2 NOV 2011, DOI: 10.1111/j.1365-2036.2011.04905.x

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    British Association of Dermatologists’ guidelines for the safe and effective prescribing of azathioprine 2011

    British Journal of Dermatology

    Volume 165, Issue 4, October 2011, Pages: 711–734, S.J. Meggitt, A.V. Anstey, M.F. Mohd Mustapa, N.J. Reynolds and S. Wakelin

    Version of Record online : 27 SEP 2011, DOI: 10.1111/j.1365-2133.2011.10575.x

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    Review article: thiopurines in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 24, Issue 5, September 2006, Pages: 715–729, L. J. J. DERIJKS, L. P. L. GILISSEN, P. M. HOOYMANS and D. W. HOMMES

    Version of Record online : 16 AUG 2006, DOI: 10.1111/j.1365-2036.2006.02980.x

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    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Version of Record online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  7. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 29 NOV 2014, DOI: 10.1111/bjh.13240

  8. Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait

    Clinical Pharmacology & Therapeutics

    C Liu, W Yang, D Pei, C Cheng, C Smith, W Landier, L Hageman, Y Chen, JJ Yang, KR Crews, N Kornegay, SE Karol, FL Wong, S Jeha, JT Sandlund, RC Ribeiro, JE Rubnitz, ML Metzger, C-H Pui, WE Evans, S Bhatia and MV Relling

    Version of Record online : 18 NOV 2016, DOI: 10.1002/cpt.463

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    Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population

    British Journal of Pharmacology

    Volume 125, Issue 4, October 1998, Pages: 879–887, Catherine Spire-Vayron de la Moureyre, Hervé Debuysere, Bruno Mastain, Elizabeth Vinner, Delphine Marez, Jean-Marc Lo Guidice, Dany Chevalier, Serge Brique, Kokou Motte, Jean-Frédéric Colombel, Dominique Turck, Christian Noel, René-Marc Flipo, Annie Pol, Michel Lhermitte, Jean-Jacques Lafitte, Christian Libersa and Franck Broly

    Version of Record online : 3 FEB 2009, DOI: 10.1038/sj.bjp.0702152

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    Thiopurine metabolism monitoring: implications in inflammatory bowel diseases

    European Journal of Clinical Investigation

    Volume 40, Issue 11, November 2010, Pages: 1037–1047, Olivier Dewit, Peter Starkel and Xavier Roblin

    Version of Record online : 19 AUG 2010, DOI: 10.1111/j.1365-2362.2010.02346.x

  11. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 5 MAY 2015, DOI: 10.1111/bjh.13469

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    Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

    Clinical Pharmacology & Therapeutics

    Volume 89, Issue 3, March 2011, Pages: 387–391, MV Relling, EE Gardner, WJ Sandborn, K Schmiegelow, C-H Pui, SW Yee, CM Stein, M Carrillo, WE Evans and TE Klein

    Version of Record online : 26 JAN 2011, DOI: 10.1038/clpt.2010.320

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    Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

    British Journal of Clinical Pharmacology

    Volume 48, Issue 6, December 1999, Pages: 793–800, Dervieux, Médard, Baudouin, Maisin, Zhang, Broly, Loirat and Jacqz-Aigrain

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00087.x

  14. Normal thiopurine methyltransferase phenotype testing in a Crohn disease patient with azathioprine induced myelosuppression

    Internal Medicine Journal

    Volume 39, Issue 2, February 2009, Pages: 121–126, M. Leung, 1 I. Piatkov, 2 C. Rochester, 2 S. C. Boyages and 2 R. W. L. Leong 1

    Version of Record online : 31 MAR 2009, DOI: 10.1111/j.1445-5994.2008.01855.x

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    High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment

    Alimentary Pharmacology & Therapeutics

    Volume 35, Issue 10, May 2012, Pages: 1181–1189, R. van Egmond, P. Chin, M. Zhang, C. W. Sies and M. L. Barclay

    Version of Record online : 4 APR 2012, DOI: 10.1111/j.1365-2036.2012.05084.x

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    Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 20, Issue 8, August 2005, Pages: 1149–1157, RICHARD B GEARRY and MURRAY L BARCLAY

    Version of Record online : 11 MAY 2005, DOI: 10.1111/j.1440-1746.2005.03832.x

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    Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 25, Issue 9, May 2007, Pages: 1069–1077, J. W. WINTER, D. GAFFNEY, D SHAPIRO, R. J. SPOONER, A. M. MARINAKI, J. D. SANDERSON and P. R. MILLS

    Version of Record online : 22 FEB 2007, DOI: 10.1111/j.1365-2036.2007.03301.x

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    Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: A comparison of Han and Yao ethnic groups

    British Journal of Clinical Pharmacology

    Volume 58, Issue 2, August 2004, Pages: 163–168, Jian-ping Zhang, Yong-yuan Guan, Jue-heng Wu, An-Long Xu, Shufeng Zhou and Min Huang

    Version of Record online : 4 JUN 2004, DOI: 10.1111/j.1365-2125.2004.02113.x

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    Adverse events leading to modification of therapy in a large cohort of patients with inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 24, Issue 2, July 2006, Pages: 331–342, U. HINDORF, M. LINDQVIST, H. HILDEBRAND, U. FAGERBERG and S. ALMER

    Version of Record online : 26 JUN 2006, DOI: 10.1111/j.1365-2036.2006.02977.x

  20. TPMT genotype and its clinical implication in renal transplant recipients with azathioprine treatment

    Journal of Clinical Pharmacy and Therapeutics

    Volume 31, Issue 6, December 2006, Pages: 627–635, D.-K. Song, J. Zhao and L.-R. Zhang

    Version of Record online : 24 NOV 2006, DOI: 10.1111/j.1365-2710.2006.00775.x