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There are 8168 results for: content related to: Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors

  1. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2

    Human Mutation

    Volume 33, Issue 6, June 2012, Pages: 998–1009, Kevin Cheeseman, Etienne Rouleau, Anne Vannier, Aurélie Thomas, Adrien Briaux, Cedrick Lefol, Pierre Walrafen, Aaron Bensimon, Rosette Lidereau, Emmanuel Conseiller and Maurizio Ceppi

    Article first published online : 4 APR 2012, DOI: 10.1002/humu.22060

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    ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

    The EMBO Journal

    Volume 25, Issue 10, May 17, 2006, Pages: 2167–2177, Liu Cao, Sangsoo Kim, Cuiying Xiao, Rui-Hong Wang, Xavier Coumoul, Xiaoyan Wang, Wen Mei Li, Xiao Ling Xu, Joseph A De Soto, Hiroyuki Takai, Sabine Mai, Stephen J Elledge, Noboru Motoyama and Chu-Xia Deng

    Article first published online : 4 MAY 2006, DOI: 10.1038/sj.emboj.7601115

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    BRCA2 is required for neurogenesis and suppression of medulloblastoma

    The EMBO Journal

    Volume 26, Issue 11, June 6, 2007, Pages: 2732–2742, Pierre-Olivier Frappart, Youngsoo Lee, Jayne Lamont and Peter J McKinnon

    Article first published online : 3 MAY 2007, DOI: 10.1038/sj.emboj.7601703

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    Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

    The EMBO Journal

    Volume 20, Issue 17, September 3, 2001, Pages: 4704–4716, Andrew Tutt, David Bertwistle, Janet Valentine, Anastasia Gabriel, Sally Swift, Gillian Ross, Carol Griffin, John Thacker and Alan Ashworth

    Article first published online : 3 SEP 2001, DOI: 10.1093/emboj/20.17.4704

  5. Multiple copies of mutant BRCA1 and BRCA2 alleles in breast tumors from germ-line mutation carriers

    Genes, Chromosomes and Cancer

    Volume 28, Issue 4, August 2000, Pages: 432–442, Synnöve Staff, Nina N. Nupponen, Åke Borg, Jorma J. Isola and Minna M. Tanner

    Article first published online : 14 JUN 2000, DOI: 10.1002/1098-2264(200008)28:4<432::AID-GCC9>3.0.CO;2-J

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    BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana

    New Phytologist

    Volume 193, Issue 2, January 2012, Pages: 364–375, Katharina Seeliger, Stefanie Dukowic-Schulze, Rebecca Wurz-Wildersinn, Michael Pacher and Holger Puchta

    Article first published online : 11 NOV 2011, DOI: 10.1111/j.1469-8137.2011.03947.x

  7. Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells

    The Journal of Pathology

    Volume 234, Issue 3, November 2014, Pages: 386–397, Hong Xu, Jian Xian, Emmanuelle Vire, Steven McKinney, Vivien Wei, Jason Wong, Rebecca Tong, Tony Kouzarides, Carlos Caldas and Samuel Aparicio

    Article first published online : 28 AUG 2014, DOI: 10.1002/path.4404

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    Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy


    Volume 32, Issue 2, February 2014, Pages: 436–446, S. Navarro, V. Moleiro, F.J. Molina-Estevez, M.L. Lozano, R. Chinchon, E. Almarza, O. Quintana-Bustamante, G. Mostoslavsky, T. Maetzig, M. Galla, N. Heinz, B. Schiedlmeier, Y. Torres, U. Modlich, E. Samper, P. Río, J.C. Segovia, A. Raya, G. Güenechea, J.C. Izpisua-Belmonte and J.A. Bueren

    Article first published online : 13 JAN 2014, DOI: 10.1002/stem.1586

  9. BRCA1-Mediated Inflammation and Growth Activated & Inhibited Transition Mechanisms Between No-Tumor Hepatitis/Cirrhotic Tissues and HCC

    Journal of Cellular Biochemistry

    Volume 115, Issue 4, April 2014, Pages: 641–650, Haizhen Diao, Lin Wang, Juxiang Huang, Minghu Jiang, Huilei Zhou, Xiaohe Li, Qingchun Chen, Zhenfu Jiang and Haitao Feng

    Article first published online : 23 JAN 2014, DOI: 10.1002/jcb.24699

  10. Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2–Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis

    Genes, Chromosomes and Cancer

    Volume 44, Issue 4, December 2005, Pages: 429–437, Boyko S. Atanassov, J. Carl Barrett and Barbara J. Davis

    Article first published online : 26 AUG 2005, DOI: 10.1002/gcc.20255

  11. Disruption of BRCA1 function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines

    Genes, Chromosomes and Cancer

    Volume 45, Issue 3, March 2006, Pages: 277–289, Juliet D. French, Jasmyn Dunn, Chanel E. Smart, Nathan Manning and Melissa A. Brown

    Article first published online : 10 NOV 2005, DOI: 10.1002/gcc.20290

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    Poly(ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

    CA: A Cancer Journal for Clinicians

    Volume 61, Issue 1, January/February 2011, Pages: 31–49, Timothy A. Yap, Shahneen K. Sandhu, Craig P. Carden and Johann S. de Bono

    Article first published online : 4 JAN 2011, DOI: 10.3322/caac.20095

  13. Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors

    Genes, Chromosomes and Cancer

    Volume 50, Issue 2, February 2011, Pages: 71–81, Simon A. Joosse, Kim I. M. Brandwijk, Lennart Mulder, Jelle Wesseling, Juliane Hannemann and Petra M. Nederlof

    Article first published online : 22 NOV 2010, DOI: 10.1002/gcc.20833

  14. E2F3b over-expression in ovarian carcinomas and in BRCA1 Haploinsufficient fallopian tube epithelium

    Genes, Chromosomes and Cancer

    Volume 51, Issue 11, November 2012, Pages: 1054–1062, Na Lu Smith, Piri Welcsh, Joshua Z. Press, Kathy J. Agnew, Rochelle Garcia and Elizabeth M. Swisher

    Article first published online : 9 AUG 2012, DOI: 10.1002/gcc.21990

  15. Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A

    Genes, Chromosomes and Cancer

    Volume 39, Issue 3, March 2004, Pages: 236–248, Patricia A. Mote, Jennifer A. Leary, Kelly A. Avery, Kerstin Sandelin, Georgia Chenevix-Trench, Judy A. Kirk and Christine L. Clarke

    Article first published online : 8 JAN 2004, DOI: 10.1002/gcc.10321

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    The molecular pathogenesis of hereditary ovarian carcinoma


    Volume 116, Issue 22, 15 November 2010, Pages: 5261–5271, Barbara M. Norquist, Rochelle L. Garcia, Kimberly H. Allison, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi, Bethany J. Barrow, Barbara A. Goff and Elizabeth M. Swisher

    Article first published online : 3 NOV 2010, DOI: 10.1002/cncr.25439

  17. Double Heterozygotes for Non-Caucasian Families with Mutations in BRCA-1 and BRCA-2 Genes

    The Breast Journal

    Volume 12, Issue 3, May 2006, Pages: 216–220, Doo Ho Choi, Min Hyuk Lee and Bruce G. Haffty

    Article first published online : 2 MAY 2006, DOI: 10.1111/j.1075-122X.2006.00245.x

  18. Thymic model for examining BRCA2 expression and function

    Molecular Carcinogenesis

    Volume 35, Issue 3, November 2002, Pages: 103–109, Kristina G. Flores, Kimberly A. McAllister, Paula K. Greer, Roger W. Wiseman and Laura P. Hale

    Article first published online : 29 OCT 2002, DOI: 10.1002/mc.10081

  19. Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: A possible molecular link between stress and breast cancer

    Genes, Chromosomes and Cancer

    Volume 47, Issue 4, April 2008, Pages: 341–352, Lilia Antonova and Christopher R. Mueller

    Article first published online : 14 JAN 2008, DOI: 10.1002/gcc.20538

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    DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter

    International Journal of Cancer

    Volume 111, Issue 5, 20 September 2004, Pages: 669–678, Darci T. Butcher, Debora N. Mancini-DiNardo, Trevor K. Archer and David I. Rodenhiser

    Article first published online : 20 MAY 2004, DOI: 10.1002/ijc.20324