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There are 23296 results for: content related to: Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma

  1. Oncogenic PIK3CA mutations in lobular breast cancer progression

    Genes, Chromosomes and Cancer

    Volume 52, Issue 1, January 2013, Pages: 69–80, Matthias Christgen, Monika Noskowicz, Elisa Schipper, Henriette Christgen, Charlotte Heil, Till Krech, Florian Länger, Hans Kreipe and Ulrich Lehmann

    Article first published online : 21 SEP 2012, DOI: 10.1002/gcc.22007

  2. Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification

    The Journal of Pathology

    Volume 214, Issue 3, February 2008, Pages: 347–356, B Angulo, A Suarez-Gauthier, F Lopez-Rios, PP Medina, E Conde, M Tang, G Soler, A Lopez-Encuentra, JC Cigudosa and M Sanchez-Cespedes

    Article first published online : 8 NOV 2007, DOI: 10.1002/path.2267

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    The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross-talk, and therapies

    Oral Diseases

    R Vander Broek, S Mohan, DF Eytan, Z Chen and C Van Waes

    Article first published online : 23 DEC 2013, DOI: 10.1111/odi.12206

  4. Mutual exclusiveness between PIK3CA and KRAS mutations in endometrial carcinoma

    International Journal of Gynecological Cancer

    Volume 18, Issue 6, November/December 2008, Pages: 1339–1343, S. KANG, S.S. SEO, H.J. CHANG, C.W. YOO, S.Y. PARK and S.M. DONG

    Article first published online : 25 JAN 2008, DOI: 10.1111/j.1525-1438.2007.01172.x

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    Oncogenic PIK3CA mutations in colorectal cancers and polyps

    International Journal of Cancer

    Volume 131, Issue 4, 15 August 2012, Pages: 813–820, Vicki L.J. Whitehall, Celestine Rickman, Catherine E. Bond, Ingunn Ramsnes, Sonia A. Greco, Aarti Umapathy, Diane McKeone, Rebecca J. Faleiro, Ron L. Buttenshaw, Daniel L. Worthley, Sam Nayler, Zhen Zhen Zhao, Grant W. Montgomery, Kylie-Ann Mallitt, Jeremy R. Jass, Nagahide Matsubara, Kenji Notohara, Tatsuhiro Ishii and Barbara A. Leggett

    Article first published online : 19 NOV 2011, DOI: 10.1002/ijc.26440

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    Lessons learned from next-generation sequencing in head and neck cancer

    Head & Neck

    Volume 35, Issue 3, March 2013, Pages: 454–463, Myriam Loyo, Ryan J. Li, Chetan Bettegowda, Curtis R. Pickering, Mitchell J. Frederick, Jeffrey N. Myers and Nishant Agrawal

    Article first published online : 21 AUG 2012, DOI: 10.1002/hed.23100

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    PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

    Cancer Science

    Volume 97, Issue 12, December 2006, Pages: 1351–1358, Ken-ichi Kozaki, Issei Imoto, Atiphan Pimkhaokham, Shogo Hasegawa, Hitoshi Tsuda, Ken Omura and Johji Inazawa

    Article first published online : 17 OCT 2006, DOI: 10.1111/j.1349-7006.2006.00343.x

  8. Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma

    Head & Neck

    Volume 36, Issue 8, August 2014, Pages: 1181–1188, Sean M. McBride, S. Michael Rothenberg, William C. Faquin, Annie W. Chan, John R. Clark, Leif W. Ellisen and Lori J. Wirth

    Article first published online : 10 MAR 2014, DOI: 10.1002/hed.23430

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    PIK3CA mutations in nasopharyngeal carcinoma

    International Journal of Cancer

    Volume 118, Issue 4, 15 February 2006, Pages: 1065–1067, Yvonne Yan-Yan Or, Angela Bik-Yu Hui, Ka-Fai To, Cleo Nga-Yee Lam and Kwok-Wai Lo

    Article first published online : 19 AUG 2005, DOI: 10.1002/ijc.21444

  10. Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer

    The Journal of Pathology

    Volume 219, Issue 3, November 2009, Pages: 337–346, Zeenath Jehan, Prashant Bavi, Mehar Sultana, Jehad Abubaker, Rong Bu, Azhar Hussain, Ghazi Alsbeih, Nasser Al-Sanea, Alaa Abduljabbar, Luai H Ashari, Samar Alhomoud, Fouad Al-Dayel, Shahab Uddin and Khawla S Al-Kuraya

    Article first published online : 7 JUL 2009, DOI: 10.1002/path.2601

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    Defining the genomic landscape of head and neck cancers through next-generation sequencing

    Oral Diseases

    G Rizzo, M Black, JS Mymryk, JW Barrett and AC Nichols

    Article first published online : 30 APR 2014, DOI: 10.1111/odi.12246

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    Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer

    International Journal of Cancer

    Volume 122, Issue 5, 1 March 2008, Pages: 1189–1194, Wanglong Qiu, Guo-Xia Tong, Spiros Manolidis, Lanny G. Close, Adel M. Assaad and Gloria H. Su

    Article first published online : 7 NOV 2007, DOI: 10.1002/ijc.23217

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    Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma

    International Journal of Cancer

    Volume 104, Issue 3, 10 April 2003, Pages: 318–327, Do-Sun Byun, Kyucheol Cho, Byung-Kyu Ryu, Min-Goo Lee, Jae-Il Park, Kwon-Seok Chae, Hyo-Jong Kim and Sung-Gil Chi

    Article first published online : 13 JAN 2003, DOI: 10.1002/ijc.10962

  14. You have full text access to this Open Access content
    PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma

    Cancer Science

    Volume 100, Issue 11, November 2009, Pages: 2034–2039, Ali Fendri, Abdelmajid Khabir, Wafa Mnejja, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Abdelmonem Ghorbel, Ali Gargouri and Raja Mokdad-Gargouri

    Article first published online : 21 JUL 2009, DOI: 10.1111/j.1349-7006.2009.01292.x

  15. Tumor Heterogeneity Revealed by KRAS, BRAF, and PIK3CA Pyrosequencing: KRAS and PIK3CA Intratumor Mutation Profile Differences and Their Therapeutic Implications

    Human Mutation

    Volume 35, Issue 3, March 2014, Pages: 329–340, Vivian Kosmidou, Eftychia Oikonomou, Margarita Vlassi, Spyros Avlonitis, Anastasia Katseli, Iraklis Tsipras, Despina Mourtzoukou, Georgios Kontogeorgos, Georgios Zografos and Alexander Pintzas

    Article first published online : 15 JAN 2014, DOI: 10.1002/humu.22496

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    PIK3CA mutation is predictive of poor survival in patients with colorectal cancer

    International Journal of Cancer

    Volume 121, Issue 8, 15 October 2007, Pages: 1771–1778, Shunsuke Kato, Satoru Iida, Tetsuro Higuchi, Toshiaki Ishikawa, Yoko Takagi, Masamichi Yasuno, Masayuki Enomoto, Hiroyuki Uetake and Kenichi Sugihara

    Article first published online : 22 JUN 2007, DOI: 10.1002/ijc.22890

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    Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas


    Volume 118, Issue 23, 1 December 2012, Pages: 5878–5887, Antoine Italiano, Chun-Liang Chen, Rachael Thomas, Matthew Breen, Françoise Bonnet, Nicolas Sevenet, Michel Longy, Robert G. Maki, Jean-Michel Coindre and Cristina R. Antonescu

    Article first published online : 30 MAY 2012, DOI: 10.1002/cncr.27614

  18. PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors

    Molecular Carcinogenesis

    Marta Dueñas, Mónica Martínez-Fernández, Ramón García-Escudero, Felipe Villacampa, Miriam Marqués, Cristina Saiz-Ladera, José Duarte, Victor Martínez, Mª José Gómez, Mª Luisa Martín, Manoli Fernández, Daniel Castellano, Francisco X. Real, Jose L. Rodriguez-Peralto, Federico De La Rosa and Jesús M. Paramio

    Article first published online : 18 DEC 2013, DOI: 10.1002/mc.22125

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    TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

    Human Mutation

    Volume 35, Issue 6, June 2014, Pages: 672–688, Bernard Leroy, Martha Anderson and Thierry Soussi

    Article first published online : 20 MAY 2014, DOI: 10.1002/humu.22552

  20. PIK3CA cancer mutations display gender and tissue specificity patterns

    Human Mutation

    Volume 29, Issue 2, February 2008, Pages: 284–288, Silvia Benvenuti, Milo Frattini, Sabrina Arena, Carlo Zanon, Vera Cappelletti, Danila Coradini, Maria Grazia Daidone, Silvana Pilotti, Marco A. Pierotti and Alberto Bardelli

    Article first published online : 16 NOV 2007, DOI: 10.1002/humu.20648