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There are 4298 results for: content related to: Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma

  1. Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer

    The Journal of Pathology

    Volume 219, Issue 3, November 2009, Pages: 337–346, Zeenath Jehan, Prashant Bavi, Mehar Sultana, Jehad Abubaker, Rong Bu, Azhar Hussain, Ghazi Alsbeih, Nasser Al-Sanea, Alaa Abduljabbar, Luai H Ashari, Samar Alhomoud, Fouad Al-Dayel, Shahab Uddin and Khawla S Al-Kuraya

    Article first published online : 7 JUL 2009, DOI: 10.1002/path.2601

  2. Oncogenic PIK3CA mutations in lobular breast cancer progression

    Genes, Chromosomes and Cancer

    Volume 52, Issue 1, January 2013, Pages: 69–80, Matthias Christgen, Monika Noskowicz, Elisa Schipper, Henriette Christgen, Charlotte Heil, Till Krech, Florian Länger, Hans Kreipe and Ulrich Lehmann

    Article first published online : 21 SEP 2012, DOI: 10.1002/gcc.22007

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    Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer

    International Journal of Cancer

    Volume 133, Issue 4, 15 August 2013, Pages: 984–996, Areumnuri Kim, Jung-Eun Lee, Seung-Sook Lee, Cherin Kim, Sun-Joo Lee, Won-Suk Jang and Sunhoo Park

    Article first published online : 8 MAR 2013, DOI: 10.1002/ijc.28073

  4. You have full text access to this Open Access content
    PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma

    Cancer Science

    Volume 100, Issue 11, November 2009, Pages: 2034–2039, Ali Fendri, Abdelmajid Khabir, Wafa Mnejja, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Abdelmonem Ghorbel, Ali Gargouri and Raja Mokdad-Gargouri

    Article first published online : 21 JUL 2009, DOI: 10.1111/j.1349-7006.2009.01292.x

  5. You have full text access to this Open Access content
    PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

    Cancer Science

    Volume 97, Issue 12, December 2006, Pages: 1351–1358, Ken-ichi Kozaki, Issei Imoto, Atiphan Pimkhaokham, Shogo Hasegawa, Hitoshi Tsuda, Ken Omura and Johji Inazawa

    Article first published online : 17 OCT 2006, DOI: 10.1111/j.1349-7006.2006.00343.x

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    Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer

    International Journal of Cancer

    Volume 122, Issue 5, 1 March 2008, Pages: 1189–1194, Wanglong Qiu, Guo-Xia Tong, Spiros Manolidis, Lanny G. Close, Adel M. Assaad and Gloria H. Su

    Article first published online : 7 NOV 2007, DOI: 10.1002/ijc.23217

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    Oncogenic PIK3CA mutations in colorectal cancers and polyps

    International Journal of Cancer

    Volume 131, Issue 4, 15 August 2012, Pages: 813–820, Vicki L.J. Whitehall, Celestine Rickman, Catherine E. Bond, Ingunn Ramsnes, Sonia A. Greco, Aarti Umapathy, Diane McKeone, Rebecca J. Faleiro, Ron L. Buttenshaw, Daniel L. Worthley, Sam Nayler, Zhen Zhen Zhao, Grant W. Montgomery, Kylie-Ann Mallitt, Jeremy R. Jass, Nagahide Matsubara, Kenji Notohara, Tatsuhiro Ishii and Barbara A. Leggett

    Article first published online : 19 NOV 2011, DOI: 10.1002/ijc.26440

  8. You have full text access to this OnlineOpen article
    PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer

    Cancer Medicine

    Volume 4, Issue 3, March 2015, Pages: 371–382, Gilles Manceau, Laetitia Marisa, Valérie Boige, Alex Duval, Marie-Pierre Gaub, Gérard Milano, Janick Selves, Sylviane Olschwang, Valérie Jooste, Michè le Legrain, Delphine Lecorre, Dominique Guenot, Marie-Christine Etienne-Grimaldi, Sylvain Kirzin, Laurent Martin, Come Lepage, Anne-Marie Bouvier and Pierre Laurent-Puig

    Article first published online : 2 FEB 2015, DOI: 10.1002/cam4.370

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    Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma

    International Journal of Cancer

    Volume 104, Issue 3, 10 April 2003, Pages: 318–327, Do-Sun Byun, Kyucheol Cho, Byung-Kyu Ryu, Min-Goo Lee, Jae-Il Park, Kwon-Seok Chae, Hyo-Jong Kim and Sung-Gil Chi

    Article first published online : 13 JAN 2003, DOI: 10.1002/ijc.10962

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    Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors

    FEBS Journal

    Volume 280, Issue 12, June 2013, Pages: 2758–2765, Shany Koren and Mohamed Bentires-Alj

    Article first published online : 1 MAR 2013, DOI: 10.1111/febs.12175

  11. PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors

    Molecular Carcinogenesis

    Volume 54, Issue 7, July 2015, Pages: 566–576, Marta Dueñas, Mónica Martínez-Fernández, Ramón García-Escudero, Felipe Villacampa, Miriam Marqués, Cristina Saiz-Ladera, José Duarte, Victor Martínez, Mª José Gómez, Mª Luisa Martín, Manoli Fernández, Daniel Castellano, Francisco X. Real, Jose L. Rodriguez-Peralto, Federico De La Rosa and Jesús M. Paramio

    Article first published online : 18 DEC 2013, DOI: 10.1002/mc.22125

  12. You have full text access to this OnlineOpen article
    Prognostic role of PIK3CA mutations of cell-free DNA in early-stage triple negative breast cancer

    Cancer Science

    Volume 106, Issue 11, November 2015, Pages: 1582–1589, Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Toko Inao, Aiko Sueta, Saori Fujiwara, Yoko Omoto and Hirotaka Iwase

    Article first published online : 30 OCT 2015, DOI: 10.1111/cas.12813

  13. Tumor Heterogeneity Revealed by KRAS, BRAF, and PIK3CA Pyrosequencing: KRAS and PIK3CA Intratumor Mutation Profile Differences and Their Therapeutic Implications

    Human Mutation

    Volume 35, Issue 3, March 2014, Pages: 329–340, Vivian Kosmidou, Eftychia Oikonomou, Margarita Vlassi, Spyros Avlonitis, Anastasia Katseli, Iraklis Tsipras, Despina Mourtzoukou, Georgios Kontogeorgos, Georgios Zografos and Alexander Pintzas

    Article first published online : 15 JAN 2014, DOI: 10.1002/humu.22496

  14. Mutual exclusiveness between PIK3CA and KRAS mutations in endometrial carcinoma

    International Journal of Gynecological Cancer

    Volume 18, Issue 6, November/December 2008, Pages: 1339–1343, S. KANG, S.S. SEO, H.J. CHANG, C.W. YOO, S.Y. PARK and S.M. DONG

    Article first published online : 25 JAN 2008, DOI: 10.1111/j.1525-1438.2007.01172.x

  15. PIK3CA mutation and histological type in breast carcinoma: high frequency of mutations in lobular carcinoma

    The Journal of Pathology

    Volume 208, Issue 3, February 2006, Pages: 350–355, Fiamma Buttitta, Lara Felicioni, Fabio Barassi, Carla Martella, Diego Paolizzi, Giuseppina Fresu, Simona Salvatore, Franco Cuccurullo, Andrea Mezzetti, Daniela Campani and Antonio Marchetti

    Article first published online : 13 DEC 2005, DOI: 10.1002/path.1908

  16. FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra

    British Journal of Dermatology

    Volume 162, Issue 3, March 2010, Pages: 508–512, C. Hafner, M. Landthaler, T. Mentzel and T. Vogt

    Article first published online : 1 SEP 2009, DOI: 10.1111/j.1365-2133.2009.09488.x

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    PIK3CA mutation is predictive of poor survival in patients with colorectal cancer

    International Journal of Cancer

    Volume 121, Issue 8, 15 October 2007, Pages: 1771–1778, Shunsuke Kato, Satoru Iida, Tetsuro Higuchi, Toshiaki Ishikawa, Yoko Takagi, Masamichi Yasuno, Masayuki Enomoto, Hiroyuki Uetake and Kenichi Sugihara

    Article first published online : 22 JUN 2007, DOI: 10.1002/ijc.22890

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    PIK3CA mutations in nasopharyngeal carcinoma

    International Journal of Cancer

    Volume 118, Issue 4, 15 February 2006, Pages: 1065–1067, Yvonne Yan-Yan Or, Angela Bik-Yu Hui, Ka-Fai To, Cleo Nga-Yee Lam and Kwok-Wai Lo

    Article first published online : 19 AUG 2005, DOI: 10.1002/ijc.21444

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    Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3255–3267, B Bhattacharya, S H H Low, C Soh, N Kamal Mustapa, M Beloueche-Babari, K X Koh, J Loh and R Soong

    Article first published online : 10 JUN 2014, DOI: 10.1111/bph.12668

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    Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations

    Experimental Dermatology

    Volume 19, Issue 8, August 2010, Pages: e222–e227, Christian Hafner, Michael Landthaler and Thomas Vogt

    Article first published online : 14 JUN 2010, DOI: 10.1111/j.1600-0625.2009.01056.x