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There are 4542 results for: content related to: Genetic polymorphism in the conjugating enzyme UGT1A1 and the risk of head and neck cancer

  1. Combined UGT1A1 and UGT1A7 variant alleles are associated with increased risk of Gilbert’s syndrome in Taiwanese adults

    Clinical Genetics

    Volume 72, Issue 4, October 2007, Pages: 321–328, H-C Teng, M-J Huang, K-S Tang, S-S Yang, C-S Tseng and C-S Huang

    Version of Record online : 6 AUG 2007, DOI: 10.1111/j.1399-0004.2007.00873.x

  2. You have full text access to this OnlineOpen article
    Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice

    Hepatology

    Volume 56, Issue 2, August 2012, Pages: 658–667, Shujuan Chen, Mei-Fei Yueh, Ronald M. Evans and Robert H. Tukey

    Version of Record online : 11 JUN 2012, DOI: 10.1002/hep.25671

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    Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation

    Hepatology

    Volume 55, Issue 6, June 2012, Pages: 1912–1921, Ursula Ehmer, Sandra Kalthoff, Bastian Fakundiny, Brigitte Pabst, Nicole Freiberg, Ronald Naumann, Michael P. Manns and Christian P. Strassburg

    Version of Record online : 23 APR 2012, DOI: 10.1002/hep.25561

  4. Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk

    Head & Neck

    Volume 35, Issue 6, June 2013, Pages: 858–867, Martin Lacko, Adri C. Voogd, Hennie M. J. Roelofs, Rene H. M. te Morsche, Michel B. Oude Ophuis, Wilbert H. M. Peters and Johannes J. Manni

    Version of Record online : 19 JUN 2012, DOI: 10.1002/hed.23054

  5. Genotype of UGT1A1 and phenotype correlation between Crigler–Najjar syndrome type II and Gilbert syndrome

    Journal of Gastroenterology and Hepatology

    Volume 31, Issue 2, February 2016, Pages: 403–408, Yoshihiro Maruo, Sayuri Nakahara, Takahide Yanagi, Akitaka Nomura, Yu Mimura, Katsuyuki Matsui, Hiroshi Sato and Yoshihiro Takeuchi

    Version of Record online : 28 JAN 2016, DOI: 10.1111/jgh.13071

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    UGT1A1*6,1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan

    Cancer Science

    Volume 104, Issue 12, December 2013, Pages: 1662–1669, Shoichi Hazama, Hideyuki Mishima, Ryouichi Tsunedomi, Yusuke Okuyama, Takeshi Kato, Ken-ichi Takahashi, Hiroshi Nozawa, Hideaki Ando, Michiya Kobayashi, Hiroyoshi Takemoto, Naoki Nagata, Shinsuke Kanekiyo, Yuka Inoue, Yoshihiko Hamamoto, Yusuke Fujita, Yuji Hinoda, Naoko Okayama, Koji Oba, Jun-ichi Sakamoto and Masaaki Oka

    Version of Record online : 27 OCT 2013, DOI: 10.1111/cas.12283

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    Regulation of the UGT1A1 bilirubin-conjugating pathway: Role of a new splicing event at the UGT1A locus

    Hepatology

    Volume 45, Issue 1, January 2007, Pages: 128–138, Eric Lévesque, Hugo Girard, Kim Journault, Johanie Lépine and Chantal Guillemette

    Version of Record online : 22 DEC 2006, DOI: 10.1002/hep.21464

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    Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer

    Cancer Science

    Volume 97, Issue 11, November 2006, Pages: 1255–1259, Kazuhiro Araki, Ken-ichi Fujita, Yuichi Ando, Fumio Nagashima, Wataru Yamamoto, Hisashi Endo, Toshimichi Miya, Keiji Kodama, Masaru Narabayashi and Yasutsuna Sasaki

    Version of Record online : 12 SEP 2006, DOI: 10.1111/j.1349-7006.2006.00321.x

  9. Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer

    The Journal of Clinical Pharmacology

    Volume 56, Issue 4, April 2016, Pages: 461–473, Andrew K. L. Goey, Tristan M. Sissung, Cody J. Peer, Jane B. Trepel, Min-Jung Lee, Yusuke Tomita, Sheryl Ehrlich, Christine Bryla, Sanjeeve Balasubramaniam, Richard Piekarz, Seth M. Steinberg, Susan E. Bates and William D. Figg

    Version of Record online : 9 NOV 2015, DOI: 10.1002/jcph.625

  10. You have full text access to this OnlineOpen article
    Prospective study of the UGT1A1*27 gene polymorphism during irinotecan therapy in patients with lung cancer: Results of Lung Oncology Group in Kyusyu (LOGIK1004B)

    Thoracic Cancer

    Volume 7, Issue 4, July 2016, Pages: 467–472, Minoru Fukuda, Takayuki Suetsugu, Midori Shimada, Takeshi Kitazaki, Kohji Hashiguchi, Junji Kishimoto, Taishi Harada, Takashi Seto, Noriyuki Ebi, Koichi Takayama, Kenji Sugio, Hiroshi Semba, Yoichi Nakanishi and Yukito Ichinose

    Version of Record online : 11 MAY 2016, DOI: 10.1111/1759-7714.12360

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    The role of chrysin and the Ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice

    Hepatology

    Volume 45, Issue 2, February 2007, Pages: 349–360, Jessica A. Bonzo, Alain Bélanger and Robert H. Tukey

    Version of Record online : 26 JAN 2007, DOI: 10.1002/hep.21481

  12. UDP-Glucuronosyltransferases: Pharmacogenetics, Functional Characterization, and Clinical Relevance

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Robert S. Foti and Michael B. Fisher

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm015

  13. UDP-Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 87, Issue 1, January 2010, Pages: 65–73, S Riedmaier, K Klein, U Hofmann, J E Keskitalo, P J Neuvonen, M Schwab, M Niemi and U M Zanger

    Version of Record online : 30 SEP 2009, DOI: 10.1038/clpt.2009.181

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    UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver

    Hepatology

    Volume 42, Issue 2, August 2005, Pages: 448–457, Hugo Girard, Jean Thibaudeau, Michael H. Court, Louis-Charles Fortier, Lyne Villeneuve, Patrick Caron, Qin Hao, Lisa L. von Moltke, David J. Greenblatt and Chantal Guillemette

    Version of Record online : 28 JUN 2005, DOI: 10.1002/hep.20770

  15. UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice

    Fundamental & Clinical Pharmacology

    Volume 29, Issue 3, June 2015, Pages: 219–237, Marie-Christine Etienne-Grimaldi, Jean-Christophe Boyer, Fabienne Thomas, Sylvie Quaranta, Nicolas Picard, Marie-Anne Loriot, Céline Narjoz, Delphine Poncet, Marie-Claude Gagnieu, Cécile Ged, Franck Broly, Valérie Le Morvan, Régis Bouquié, Marie-Pierre Gaub, Laurent Philibert, François Ghiringhelli, Chantal Le Guellec and Collective work by the Groupe de Pharmacologie Clinique Oncologique (GPCO-Unicancer) and the French Réseau National de Pharmacogénétique Hospitalière (RNPGx)

    Version of Record online : 4 MAY 2015, DOI: 10.1111/fcp.12117

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    Effect of UGT1A1, UGT1A3, DIO1 and DIO2 polymorphisms on L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer

    British Journal of Clinical Pharmacology

    Volume 78, Issue 5, November 2014, Pages: 1067–1075, Ana B. Santoro, Daniela D. Vargens, Mateus de Camargo Barros Filho, Daniel A. Bulzico, Luiz Paulo Kowalski, Ricardo M. R. Meirelles, Daniela P. Paula, Ronaldo R. S. Neves, Cencita N. Pessoa, Claudio J. Struchine and Guilherme Suarez-Kurtz

    Version of Record online : 20 OCT 2014, DOI: 10.1111/bcp.12437

  17. The Role of SN-38 Exposure, UGT1A1*28 Polymorphism, and Baseline Bilirubin Level in Predicting Severe Irinotecan Toxicity

    The Journal of Clinical Pharmacology

    Volume 47, Issue 1, January 2007, Pages: 78–86, Dr Roshni P. Ramchandani, Dr Yaning Wang, Dr Brian P. Booth, Dr Amna Ibrahim, Dr John R. Johnson, Dr Atiqur Rahman, Dr Mehul Mehta, Dr Federico Innocenti, Dr Mark J. Ratain and Dr Jogarao V. S. Gobburu

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270006295060

  18. You have full text access to this Open Access content
    Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms

    Cancer Science

    Volume 102, Issue 10, October 2011, Pages: 1868–1873, Taroh Satoh, Takashi Ura, Yasuhide Yamada, Kentaro Yamazaki, Toshimasa Tsujinaka, Masaki Munakata, Tomohiro Nishina, Shu Okamura, Taito Esaki, Yasutsuna Sasaki, Wasaburo Koizumi, Yoshihiro Kakeji, Naoki Ishizuka, Ichinosuke Hyodo and Yuh Sakata

    Version of Record online : 12 AUG 2011, DOI: 10.1111/j.1349-7006.2011.02030.x

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    Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients

    Cancer Science

    Volume 98, Issue 9, September 2007, Pages: 1461–1467, Srinivasa Rao Jada, Robert Lim, Chiung Ing Wong, Xiaochen Shu, Soo Chin Lee, Qingyu Zhou, Boon Cher Goh and Balram Chowbay

    Version of Record online : 11 JUL 2007, DOI: 10.1111/j.1349-7006.2007.00541.x

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    Gilbert's disease and atazanavir: From phenotype to UDP-glucuronosyltransferase haplotype

    Hepatology

    Volume 44, Issue 5, November 2006, Pages: 1324–1332, Tim O. Lankisch, Ulrike Moebius, Michael Wehmeier, Georg Behrens, Michael P. Manns, Reinhold E. Schmidt and Christian P. Strassburg

    Version of Record online : 20 OCT 2006, DOI: 10.1002/hep.21361