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There are 8028 results for: content related to: KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

  1. Anti-EGFR Monoclonal Antibodies for Treatment of Colorectal Cancers: Development of Cetuximab and Panitumumab

    The Journal of Clinical Pharmacology

    Volume 52, Issue 2, February 2012, Pages: 128–155, Dr Benoit You and Dr Eric X. Chen

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010395940

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    Cost-effectiveness of KRAS testing in metastatic colorectal cancer patients in the United States and Germany

    International Journal of Cancer

    Volume 131, Issue 2, 15 July 2012, Pages: 438–445, Arthi Vijayaraghavan, Molly B. Efrusy, Burkhard Göke, Thomas Kirchner, Christopher C. Santas and Richard M. Goldberg

    Article first published online : 3 JAN 2012, DOI: 10.1002/ijc.26400

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    Review article: panitumumab - a fully human anti-EGFR monoclonal antibody for treatment of metastatic colorectal cancer

    Alimentary Pharmacology & Therapeutics

    Volume 28, Issue 3, August 2008, Pages: 269–281, M. PEETERS, J. BALFOUR and D. ARNOLD

    Article first published online : 4 JUL 2008, DOI: 10.1111/j.1365-2036.2008.03717.x

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    Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy


    Volume 115, Issue 7, 1 April 2009, Pages: 1544–1554, Marc Peeters, Salvatore Siena, Eric Van Cutsem, Alberto Sobrero, Alain Hendlisz, Stefano Cascinu, Haralabos Kalofonos, Giovanna Devercelli, Michael Wolf and Rafael G. Amado

    Article first published online : 2 FEB 2009, DOI: 10.1002/cncr.24088

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    Controversies in antiepidermal growth factor receptor therapy in metastatic colorectal cancer


    Volume 119, Issue 11, 1 June 2013, Pages: 1941–1950, Janghee Woo, Neil Palmisiano, William Tester and John C. Leighton Jr.

    Article first published online : 15 MAR 2013, DOI: 10.1002/cncr.27994

  6. The neoadjuvant therapy of colorectal hepatic metastases and the role of biologic sensitizing and resistance factors

    Journal of Surgical Oncology

    Volume 102, Issue 8, 15 December 2010, Pages: 891–897, Harold J. Wanebo and David Berz

    Article first published online : 16 DEC 2010, DOI: 10.1002/jso.21691

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    A systematic review of treatment guidelines for metastatic colorectal cancer

    Colorectal Disease

    Volume 14, Issue 2, February 2012, Pages: e31–e47, M. S. Edwards, S. D. Chadda, Z. Zhao, B. L. Barber and D. P. Sykes

    Article first published online : 10 JAN 2012, DOI: 10.1111/j.1463-1318.2011.02765.x

  8. Population Pharmacokinetic Analysis of Panitumumab in Patients With Advanced Solid Tumors

    The Journal of Clinical Pharmacology

    Volume 49, Issue 10, October 2009, Pages: 1142–1156, Dr Peiming Ma, Dr Bing-Bing Yang, Dr Yow-Ming Wang, Dr Mark Peterson, Mr Adimoolam Narayanan, Ms Liviawati Sutjandra, Ms Rachelle Rodriguez and Dr Andrew Chow

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009344989

  9. Panitumumab (Vectibix®): A Treatment for Metastatic Colorectal Cancer

    Handbook of Therapeutic Antibodies

    Stefan Dübel, Janice M. Reichert, Pages: 1855–1870, 2014

    Published Online : 12 AUG 2014, DOI: 10.1002/9783527682423.ch66

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    KRAS and BRAF: drug targets and predictive biomarkers

    The Journal of Pathology

    Volume 223, Issue 2, January 2011, Pages: 220–230, Efsevia Vakiani and David B Solit

    Article first published online : 28 OCT 2010, DOI: 10.1002/path.2796

  11. You have full text access to this OnlineOpen article
    Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients

    Cancer Science

    Volume 106, Issue 3, March 2015, Pages: 324–327, Hiroya Taniguchi, Kentaro Yamazaki, Takayuki Yoshino, Kei Muro, Yasushi Yatabe, Toshiaki Watanabe, Hiromichi Ebi, Atsushi Ochiai, Eishi Baba and Katsuya Tsuchihara

    Article first published online : 20 MAR 2015, DOI: 10.1111/cas.12595

  12. Circulating tumor cells as a longitudinal biomarker in patients with advanced chemorefractory, RAS-BRAF wild-type colorectal cancer receiving cetuximab or panitumumab

    International Journal of Cancer

    Volume 137, Issue 6, 15 September 2015, Pages: 1467–1474, Valeria Musella, Filippo Pietrantonio, Eleonora Di Buduo, Roberto Iacovelli, Antonia Martinetti, Elisa Sottotetti, Ilaria Bossi, Claudia Maggi, Maria Di Bartolomeo, Filippo de Braud, Maria Grazia Daidone and Vera Cappelletti

    Article first published online : 4 MAR 2015, DOI: 10.1002/ijc.29493

  13. Pharmacokinetics of Irinotecan With and Without Panitumumab Coadministration in Patients With Metastatic Colorectal Cancer

    Clinical Pharmacology in Drug Development

    Volume 2, Issue 3, July 2013, Pages: 205–212, Bing-Bing Yang, Chi-Yuan Wu, Eric Chen, Jeffrey R. Infante, Alin Chen, Bing Gao, Brian Smith, Jason Litten and Hagen Kennecke

    Article first published online : 15 MAY 2013, DOI: 10.1002/cpdd.35

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    Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent

    British Journal of Pharmacology

    Volume 157, Issue 8, August 2009, Pages: 1541–1548, GL Ray, KE Baidoo, KJ Wong, M Williams, K Garmestani, MW Brechbiel and DE Milenic

    Article first published online : 29 JUL 2009, DOI: 10.1111/j.1476-5381.2009.00327.x

  15. Preparation of clinical-grade 89Zr-panitumumab as a positron emission tomography biomarker for evaluating epidermal growth factor receptor-targeted therapy

    Journal of Labelled Compounds and Radiopharmaceuticals

    Volume 57, Issue 1, January 2014, Pages: 25–35, Ling Wei, Jianfeng Shi, George Afari and Sibaprasad Bhattacharyya

    Article first published online : 13 NOV 2013, DOI: 10.1002/jlcr.3134

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    Influence of KRAS mutation status in metachronous and synchronous metastatic colorectal adenocarcinoma


    Volume 118, Issue 24, 15 December 2012, Pages: 6243–6252, Jeffrey S. Rose, Derek S. Serna, Ludmila Katherine Martin, Xiaobai Li, Lynn M. Weatherby, Sherif Abdel-Misih, Weiqiang Zhao and Tanios Bekaii-Saab

    Article first published online : 6 JUN 2012, DOI: 10.1002/cncr.27666

  17. KRAS mutational status assessment in patients with metastatic colorectal cancer: are the clinical implications so clear?

    European Journal of Cancer Care

    Volume 19, Issue 2, March 2010, Pages: 167–171, M. HEBBAR, P. FOURNIER and O. ROMANO

    Article first published online : 20 AUG 2009, DOI: 10.1111/j.1365-2354.2009.01134.x

  18. Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study)


    Volume 122, Issue 4, February 15, 2016, Pages: 574–581, Francesco Leone, Donatella Marino, Stefano Cereda, Roberto Filippi, Carmen Belli, Rosella Spadi, Guglielmo Nasti, Massimo Montano, Alessio Amatu, Giuseppe Aprile, Celeste Cagnazzo, Gianpiero Fasola, Salvatore Siena, Libero Ciuffreda, Michele Reni and Massimo Aglietta

    Article first published online : 5 NOV 2015, DOI: 10.1002/cncr.29778

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    Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer


    Volume 118, Issue 6, 15 March 2012, Pages: 1523–1532, Fotios Loupakis, Chiara Cremolini, Lisa Salvatore, Marta Schirripa, Sara Lonardi, Vanja Vaccaro, Federica Cuppone, Diana Giannarelli, Vittorina Zagonel, Francesco Cognetti, Giampaolo Tortora, Alfredo Falcone and Emilio Bria

    Article first published online : 25 AUG 2011, DOI: 10.1002/cncr.26460

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    Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer


    Volume 110, Issue 5, 1 September 2007, Pages: 980–988, J. Randolph Hecht, Amita Patnaik, Jordan Berlin, Alan Venook, Imtiaz Malik, Simon Tchekmedyian, Lynn Navale, Rafael G. Amado and Neal J. Meropol

    Article first published online : 1 AUG 2007, DOI: 10.1002/cncr.22915