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There are 4168 results for: content related to: Blockade of HERG K + channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656

  1. You have free access to this content
    Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels

    British Journal of Pharmacology

    Volume 171, Issue 7, April 2014, Pages: 1668–1675, W J Crumb Jr

    Version of Record online : 18 MAR 2014, DOI: 10.1111/bph.12575

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    Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits

    The Journal of Physiology

    Volume 581, Issue 2, June 2007, Pages: 479–493, S. L. Cockerill, A. B. Tobin, I. Torrecilla, G. B. Willars, N. B. Standen and J. S. Mitcheson

    Version of Record online : 23 MAY 2007, DOI: 10.1113/jphysiol.2006.123414

  3. Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity

    Journal of Applied Toxicology

    Volume 27, Issue 1, January/February 2007, Pages: 78–85, Kiyokazu Yunomae, Satoko Ichisaki, Junko Matsuo, Shinichi Nagayama, Koichiro Fukuzaki, Ryoichi Nagata and Go Kito

    Version of Record online : 5 DEC 2006, DOI: 10.1002/jat.1201

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    SYMPOSIUM REVIEW: Revealing the structural basis of action of hERG potassium channel activators and blockers

    The Journal of Physiology

    Volume 588, Issue 17, September 2010, Pages: 3157–3167, Matthew Perry, Michael Sanguinetti and John Mitcheson

    Version of Record online : 31 AUG 2010, DOI: 10.1113/jphysiol.2010.194670

  5. Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs' cardiotoxic properties

    Journal of Applied Toxicology

    Volume 29, Issue 3, April 2009, Pages: 183–206, Sebastian Polak, Barbara Wiśniowska and Jerzy Brandys

    Version of Record online : 5 NOV 2008, DOI: 10.1002/jat.1395

  6. The EGFP/hERG fusion protein alter the electrophysiological properties of hERG channels in HEK293 cells

    Cell Biology International

    Volume 35, Issue 3, March 2011, Pages: 193–199, Na Huang, Jiang-Fang Lian, Jian-Hua Huo, Li-Ying Liu, Lei Ni, Xi Yang, Jian-Qing Zhou, Zong-Fang Li, Tu-Sheng Song and Chen Huang

    Version of Record online : 2 JAN 2013, DOI: 10.1042/CBI20100022

  7. You have full text access to this OnlineOpen article
    Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Roberta Gualdani, Francesco Tadini-Buoninsegni, Mariagrazia Roselli, Ivana Defrenza, Marialessandra Contino, Nicola Antonio Colabufo and Giovanni Lentini

    Version of Record online : 31 JUL 2015, DOI: 10.1002/prp2.160

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    Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization

    The Journal of Physiology

    Volume 586, Issue 12, June 2008, Pages: 2961–2973, Junko Kurokawa, Masaji Tamagawa, Nobuhiro Harada, Shin-ichiro Honda, Chang-Xi Bai, Haruaki Nakaya and Tetsushi Furukawa

    Version of Record online : 28 JUN 2008, DOI: 10.1113/jphysiol.2007.150367

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    Modulation of human ether-à-go-go-related K+ (HERG) channel inactivation by Cs+ and K+

    The Journal of Physiology

    Volume 548, Issue 3, May 2003, Pages: 691–702, Shetuan Zhang, Steven J. Kehl and David Fedida

    Version of Record online : 19 JUL 2004, DOI: 10.1111/j.1469-7793.2003.00691.x

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    Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels

    The Journal of Physiology

    Volume 558, Issue 3, August 2004, Pages: 729–744, Franklin M. Mullins, Svetlana Z. Stepanovic, Niloufar B. Gillani, Alfred L. George Jr and Jeffrey R. Balser

    Version of Record online : 27 JUL 2004, DOI: 10.1113/jphysiol.2004.065193

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    Up-regulation of miR-21 and miR-23a Contributes to As2O3-induced hERG Channel Deficiency

    Basic & Clinical Pharmacology & Toxicology

    Volume 116, Issue 6, June 2015, Pages: 516–523, Xin Zhao, Yuan-Qi Shi, Cai-Chuan Yan, Pan-feng Feng, Xue Wang, Rui Zhang, Xiao Zhang and Bao-Xin Li

    Version of Record online : 17 DEC 2014, DOI: 10.1111/bcpt.12348

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    Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes

    The Journal of Physiology

    Volume 514, Issue 3, February 1999, Pages: 667–675, M. C. Sanguinetti and Q. P. Xu

    Version of Record online : 8 SEP 2004, DOI: 10.1111/j.1469-7793.1999.667ad.x

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    N-linked glycosylation sites determine HERG channel surface membrane expression

    The Journal of Physiology

    Volume 515, Issue 1, February 1999, Pages: 41–48, Kevin Petrecca, Roxana Atanasiu, Armin Akhavan and Alvin Shrier

    Version of Record online : 8 SEP 2004, DOI: 10.1111/j.1469-7793.1999.041ad.x

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    Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue

    British Journal of Pharmacology

    Volume 169, Issue 6, July 2013, Pages: 1322–1334, R Varkevisser, M J C Houtman, T Linder, K C G de Git, H D M Beekman, R R Tidwell, A P IJzerman, A Stary-Weinzinger, M A Vos and M A G van der Heyden

    Version of Record online : 21 JUN 2013, DOI: 10.1111/bph.12208

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    Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K+ channel

    British Journal of Pharmacology

    Volume 172, Issue 12, June 2015, Pages: 3112–3125, R Mannikko, M H Bridgland-Taylor, H Pye, S Swallow, N Abi-Gerges, M J Morton and C E Pollard

    Version of Record online : 10 APR 2015, DOI: 10.1111/bph.13115

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    Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656

    FEBS Letters

    Volume 580, Issue 8, April 03, 2006, Pages: 1999–2005, John M. Ridley, James T. Milnes, Rona S. Duncan, Mark J. McPate, Andrew F. James, Harry J. Witchel and Jules C. Hancox

    Version of Record online : 7 MAR 2006, DOI: 10.1016/j.febslet.2006.02.073

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    High potency inhibition of hERG potassium channels by the sodium–calcium exchange inhibitor KB-R7943

    British Journal of Pharmacology

    Volume 165, Issue 7, April 2012, Pages: 2260–2273, Hongwei Cheng, Yihong Zhang, Chunyun Du, Christopher E Dempsey and Jules C Hancox

    Version of Record online : 9 MAR 2012, DOI: 10.1111/j.1476-5381.2011.01688.x

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    Characterization of S818L mutation in HERG C-terminus in LQT2

    FEBS Letters

    Volume 481, Issue 2, September 15, 2000, Pages: 197–203, Tadashi Nakajima, Masahiko Kurabayashi, Yoshio Ohyama, Yoshiaki Kaneko, Tetsushi Furukawa, Toshio Itoh, Yasuhiro Taniguchi, Toshihiro Tanaka, Yusuke Nakamura, Masayasu Hiraoka and Ryozo Nagai

    Version of Record online : 11 SEP 2000, DOI: 10.1016/S0014-5793(00)01988-8

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    Effect of S5P α-helix charge mutants on inactivation of hERG K+ channels

    The Journal of Physiology

    Volume 573, Issue 2, June 2006, Pages: 291–304, C. E. Clarke, A. P. Hill, J. Zhao, M. Kondo, R. N. Subbiah, T. J. Campbell and J. I. Vandenberg

    Version of Record online : 31 MAY 2006, DOI: 10.1113/jphysiol.2006.108332

  20. hERG Channel Physiology and Drug-Binding Structure–Activity Relationships

    Antitargets: Prediction and Prevention of Drug Side Effects

    Sarah Dalibalta, John S. Mitcheson, Pages: 89–108, 2008

    Published Online : 26 MAY 2008, DOI: 10.1002/9783527621460.ch4