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There are 24616 results for: content related to: Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells

  1. A survey of genetic toxicology testing in industry, contract laboratories and government

    Journal of Applied Toxicology

    Volume 4, Issue 2, April 1984, Pages: 66–74, N. E. McCarroll, M. G. Farrow, K. L. McCarthy and H. E. Scribner

    Article first published online : 11 JAN 2006, DOI: 10.1002/jat.2550040203

  2. 1984 survey of genetic toxicology testing in industry, government and academic laboratories

    Journal of Applied Toxicology

    Volume 6, Issue 3, June 1986, Pages: 211–223, M. G. Farrow, N. E. McCarroll and A. E. Auletta

    Article first published online : 11 JAN 2006, DOI: 10.1002/jat.2550060312

  3. Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells

    Journal of Applied Toxicology

    Volume 30, Issue 5, July 2010, Pages: 387–396, Hervé Lebrec, Padma Narayanan and Raymond Nims

    Article first published online : 29 JUN 2010, DOI: 10.1002/jat.1551

    Corrected by:

    Erratum: Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells

    Vol. 31, Issue 2, 190, Article first published online: 24 FEB 2011

  4. The occupational toxicologist: professionalism, morality and ethical standards in the context of legal and non-litigation issues

    Journal of Applied Toxicology

    Volume 25, Issue 6, November/December 2005, Pages: 496–513, Bryan Ballantyne

    Article first published online : 12 SEP 2005, DOI: 10.1002/jat.1085

  5. Acute and neurotoxicity of two structurally related acetylenic compounds: 5,7,11-dodecatriyn-1-ol and 5,7,11,13-octadecatetrayne-1,18-diol

    Journal of Applied Toxicology

    Volume 8, Issue 1, February 1988, Pages: 35–42, Shayne C. Gad, Brendan J. Dunn, Frances A. Gavigan, Christopher Reilly and John C. Peckham

    Article first published online : 11 JAN 2006, DOI: 10.1002/jat.2550080107

  6. Genetic toxicology studies using saccharomyces cerevisiae

    Journal of Applied Toxicology

    Volume 2, Issue 1, February 1982, Pages: 1–10, F. K. Zimmermann, V. W. Mayer and J. M. Parry

    Article first published online : 1 MAR 2006, DOI: 10.1002/jat.2550020102

  7. The acute toxicity of coal liquefaction-derived materials

    Journal of Applied Toxicology

    Volume 4, Issue 4, August 1984, Pages: 198–205, R. H. McKee, R. W. Biles, R. W. Kapp and J. P. Hinz

    Article first published online : 11 JAN 2006, DOI: 10.1002/jat.2550040408

  8. Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity

    Journal of Applied Toxicology

    Volume 27, Issue 1, January/February 2007, Pages: 78–85, Kiyokazu Yunomae, Satoko Ichisaki, Junko Matsuo, Shinichi Nagayama, Koichiro Fukuzaki, Ryoichi Nagata and Go Kito

    Article first published online : 5 DEC 2006, DOI: 10.1002/jat.1201

  9. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro

    Journal of Applied Toxicology

    Volume 27, Issue 6, November/December 2007, Pages: 582–588, F. Worek, N. Aurbek and H. Thiermann

    Article first published online : 16 MAR 2007, DOI: 10.1002/jat.1241

  10. Acetaldehyde accumulation in rat mammary tissue after an acute treatment with alcohol

    Journal of Applied Toxicology

    Volume 28, Issue 3, April 2008, Pages: 315–321, G. D. Castro, A. M. A. Delgado de Layño, S. L. Fanelli, M. E. Maciel, M. I. Díaz Gómez and J. A. Castro

    Article first published online : 22 JUN 2007, DOI: 10.1002/jat.1281

  11. Antifibrotic effect of captopril and enalapril on paraquat-induced lung fibrosis in rats

    Journal of Applied Toxicology

    Volume 27, Issue 4, July/August 2007, Pages: 342–349, Mahmoud Ghazi-Khansari, Ali Mohammadi-Karakani, Masoud Sotoudeh, Parvin Mokhtary, Ebraheim Pour-Esmaeil and Shirin Maghsoud

    Article first published online : 30 JAN 2007, DOI: 10.1002/jat.1212

  12. Matrix metalloproteinases 2 and 9 in central nervous system and their modification after vanadium inhalation

    Journal of Applied Toxicology

    Volume 28, Issue 6, August 2008, Pages: 718–723, L. Colín-Barenque, M. G. Martínez-Hernández, L. A. Baiza-Gutman, M. R. Avila-Costa, J. L. Ordóñez-Librado, P. Bizarro-Nevares, V. Rodriguez-Lara, G. Piñón-Zarate, M. Rojas-Lemus, P. Mussali-Galante and T. I. Fortoul

    Article first published online : 5 DEC 2007, DOI: 10.1002/jat.1326

  13. Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656

    Journal of Applied Toxicology

    Volume 28, Issue 2, March 2008, Pages: 104–111, Sang-Joon Park, Ki-Suk Kim and Eun-Joo Kim

    Article first published online : 21 MAY 2007, DOI: 10.1002/jat.1252

  14. Time course of the change and amelioration of nedaplatin-induced nephrotoxicity in rats

    Journal of Applied Toxicology

    Volume 28, Issue 3, April 2008, Pages: 388–398, Takeki Uehara, Noriko Tsuchiya, Aki Masuda, Mikinori Torii, Masuhisa Nakamura, Jyoji Yamate and Toshiyuki Maruyama

    Article first published online : 8 AUG 2007, DOI: 10.1002/jat.1292

  15. Pollinex® Quattro Ragweed: safety evaluation of a new allergy vaccine adjuvanted with monophosphoryl lipid A (MPL®) for the treatment of ragweed pollen allergy

    Journal of Applied Toxicology

    Volume 27, Issue 4, July/August 2007, Pages: 399–409, Paul Baldrick, Derek Richardson, Stefan R. Woroniecki and Beverley Lees

    Article first published online : 14 FEB 2007, DOI: 10.1002/jat.1223

  16. Electrophysiological study of infant and adult rats under acute intoxication with fluoroacetamide

    Journal of Applied Toxicology

    Volume 27, Issue 6, November/December 2007, Pages: 538–550, Sergey V. Kuznetsov, Richard O. Jenkins and Nikolay V. Goncharov

    Article first published online : 9 MAR 2007, DOI: 10.1002/jat.1234

  17. Respiratory peripheral chemosensory irritation, acute and repeated exposure toxicity studies with aerosols of triethylene glycol

    Journal of Applied Toxicology

    Volume 26, Issue 5, September/October 2006, Pages: 387–396, Bryan Ballantyne, William M. Snellings and James C. Norris

    Article first published online : 15 AUG 2006, DOI: 10.1002/jat.1160

  18. Mechanisms of DNA breaks induction in vivo by 5-azacytidine: paths of micronucleus induction by azaC

    Journal of Applied Toxicology

    Volume 28, Issue 3, April 2008, Pages: 254–259, P. Morales-Ramírez, T. Vallarino-Kelly and V. L. Cruz-Vallejo

    Article first published online : 8 AUG 2007, DOI: 10.1002/jat.1274

  19. Lipid peroxidation is enhanced in Yusho victims 35 years after accidental poisoning with polychlorinated biphenyls in Nagasaki, Japan

    Journal of Applied Toxicology

    Volume 27, Issue 2, March/April 2007, Pages: 195–197, Kazuhiro Shimizu, Fumihide Ogawa, Jens J Thiele, SangJae Bae and Shinichi Sato

    Article first published online : 22 DEC 2006, DOI: 10.1002/jat.1205

  20. Pancreatic response of rats fed genetically modified soybean

    Journal of Applied Toxicology

    Volume 28, Issue 2, March 2008, Pages: 217–226, Javier A. Magaña-Gómez, Guillermo López Cervantes, Gloria Yepiz-Plascencia and Ana M. Calderón de la Barca

    Article first published online : 27 NOV 2007, DOI: 10.1002/jat.1319