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There are 5729 results for: content related to: Toxic effects of microcystin-LR on the HepG2 cell line under hypoxic and normoxic conditions

  1. Potential metabolomic biomarkers for evaluation of adriamycin efficacy using a urinary 1H-NMR spectroscopy

    Journal of Applied Toxicology

    Volume 33, Issue 11, November 2013, Pages: 1251–1259, Kyu-Bong Kim, Ji-Young Yang, Seung Jun Kwack, Hyung Sik Kim, Do Hyun Ryu, Yeon-Joo Kim, Jung Yun Bae, Duck Soo Lim, Seul Min Choi, Mi Jung Kwon, Du Yeon Bang, Seong Kwang Lim, Young Woo Kim, Geum-Sook Hwang and Byung-Mu Lee

    Article first published online : 11 JUL 2012, DOI: 10.1002/jat.2778

  2. Multi-walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells

    Journal of Applied Toxicology

    Volume 32, Issue 6, June 2012, Pages: 454–464, Delia Cavallo, Carla Fanizza, Cinzia Lucia Ursini, Stefano Casciardi, Emilia Paba, Aureliano Ciervo, Anna Maria Fresegna, Raffaele Maiello, Anna Maria Marcelloni, Giuliana Buresti, Francesca Tombolini, Stefano Bellucci and Sergio Iavicoli

    Article first published online : 23 JAN 2012, DOI: 10.1002/jat.2711

  3. Short- and long-term toxicities of multi-walled carbon nanotubes in vivo and in vitro

    Journal of Applied Toxicology

    Volume 32, Issue 11, November 2012, Pages: 900–912, Shaoxian Tang, Yuechao Tang, Lingling Zhong, Kumuruz Murat, Gvlqikra Asan, Jerry Yu, Rongrong Jian, Changchun Wang and Ping Zhou

    Article first published online : 3 JUL 2012, DOI: 10.1002/jat.2748

  4. Cytotoxicity of dioscin in human gastric carcinoma cells through death receptor and mitochondrial pathways

    Journal of Applied Toxicology

    Volume 33, Issue 8, August 2013, Pages: 712–722, Mingming Hu, Lina Xu, Lianhong Yin, Yan Qi, Hua Li, Youwei Xu, Xu Han, Jinyong Peng and Xianyao Wan

    Article first published online : 14 FEB 2012, DOI: 10.1002/jat.2715

  5. Gene expression profiling reveals potential key pathways involved in pyrazinamide-mediated hepatotoxicity in Wistar rats

    Journal of Applied Toxicology

    Volume 33, Issue 8, August 2013, Pages: 807–819, Yun Zhang, Zhenzhou Jiang, Yijing Su, Mi Chen, Fu Li, Li Liu, Lixin Sun, Yun Wang, Shuang Zhang and Luyong Zhang

    Article first published online : 19 MAR 2012, DOI: 10.1002/jat.2736

  6. Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells

    Journal of Applied Toxicology

    Volume 33, Issue 8, August 2013, Pages: 756–765, Jianteng Wei, Ming Liu, Haizhou Liu, Hui Wang, Fengxia Wang, Yuyan Zhang, Lijun Han and Xiukun Lin

    Article first published online : 8 JUN 2012, DOI: 10.1002/jat.2725

  7. Molecular insights into the progression of crystalline silica-induced pulmonary toxicity in rats

    Journal of Applied Toxicology

    Volume 33, Issue 4, April 2013, Pages: 301–312, Rajendran Sellamuthu, Christina Umbright, Jenny R. Roberts, Amy Cumpston, Walter McKinney, Bean T. Chen, David Frazer, Shengqiao Li, Michael Kashon and Pius Joseph

    Article first published online : 19 MAR 2012, DOI: 10.1002/jat.2733

  8. CCR5 plays an important role in resolving an inflammatory response to single-walled carbon nanotubes

    Journal of Applied Toxicology

    Volume 33, Issue 8, August 2013, Pages: 845–853, Eun-Jung Park, Jinkyu Roh, Soo Nam Kim, Younghun Kim, Sang-Bae Han and Jin Tae Hong

    Article first published online : 22 MAR 2012, DOI: 10.1002/jat.2744

  9. Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway

    Journal of Applied Toxicology

    Volume 33, Issue 11, November 2013, Pages: 1268–1276, Zhenxing Mao, Wei Xia, Jun Wang, Tian Chen, Qianqian Zeng, Bing Xu, Weiyong Li, Xi Chen and Shunqing Xu

    Article first published online : 13 SEP 2012, DOI: 10.1002/jat.2785

  10. Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats

    Journal of Applied Toxicology

    Volume 32, Issue 11, November 2012, Pages: 920–928, K. Dziendzikowska, J. Gromadzka-Ostrowska, A. Lankoff, M. Oczkowski, A. Krawczyńska, J. Chwastowska, M. Sadowska-Bratek, E. Chajduk, M. Wojewódzka, M. Dušinská and M. Kruszewski

    Article first published online : 13 JUN 2012, DOI: 10.1002/jat.2758

  11. Maternal lead exposure during lactation persistently impairs testicular development and steroidogenesis in male offspring

    Journal of Applied Toxicology

    Volume 33, Issue 12, December 2013, Pages: 1384–1394, Hua Wang, Yan-Li Ji, Qun Wang, Xian-Feng Zhao, Huan Ning, Ping Liu, Cheng Zhang, Tao Yu, Ying Zhang, Xiu-Hong Meng and De-Xiang Xu

    Article first published online : 13 JUL 2012, DOI: 10.1002/jat.2795

  12. Sub-chronic exposure to paraoxon neither induces nor exacerbates diabetes mellitus in Wistar rat

    Journal of Applied Toxicology

    Volume 33, Issue 10, October 2013, Pages: 1036–1043, Syed M. Nurulain, Georg Petroianu, Mohamed Shafiullah, Huba Kalász, Murat Oz, Tariq Saeed, Abdu Adem and Ernest Adeghate

    Article first published online : 9 AUG 2012, DOI: 10.1002/jat.2794

  13. Cadmium exposure increases susceptibility to testicular autoimmunity in mice

    Journal of Applied Toxicology

    Volume 33, Issue 7, July 2013, Pages: 652–660, Yuki Ogawa, Masahiro Itoh, Shuichi Hirai, Shigeru Suna, Munekazu Naito, Ning Qu, Hayato Terayama, Ayumi Ikeda, Hidenobu Miyaso, Yoshiharu Matsuno, Masatoshi Komiyama and Chisato Mori

    Article first published online : 23 JAN 2012, DOI: 10.1002/jat.2713

  14. The effect of methylmercury exposure on behavior and cerebellar granule cell physiology in aged mice

    Journal of Applied Toxicology

    Volume 33, Issue 9, September 2013, Pages: 959–969, Sairam Bellum, Kerry A. Thuett, Bhupinder Bawa and Louise C. Abbott

    Article first published online : 10 AUG 2012, DOI: 10.1002/jat.2786

  15. Th2 cytokine-mediated methimazole-induced acute liver injury in mice

    Journal of Applied Toxicology

    Volume 32, Issue 10, October 2012, Pages: 823–833, Masanori Kobayashi, Satonori Higuchi, Mika Ide, Satomi Nishikawa, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi

    Article first published online : 9 MAR 2012, DOI: 10.1002/jat.2731

  16. Cadmium inhibits the ovary δ-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside

    Journal of Applied Toxicology

    Volume 33, Issue 7, July 2013, Pages: 679–684, Laura Musacchio Vargas, Melina Bucco Soares, Aryele Pinto Izaguirry, Diogo Seibert Lüdtke, Hugo C. Braga, Lucielli Savegnago, Suzi Wollenhaupt, Daniela dos Santos Brum, Fábio Gallas Leivas and Francielli Weber Santos

    Article first published online : 4 JUL 2012, DOI: 10.1002/jat.2783

  17. Genotoxicity evaluation of titanium dioxide nanoparticles using the Ames test and Comet assay

    Journal of Applied Toxicology

    Volume 32, Issue 11, November 2012, Pages: 934–943, Robert S. Woodruff, Yan Li, Jian Yan, Michelle Bishop, M. Yvonne Jones, Fumiya Watanabe, Alexandru S. Biris, Penelope Rice, Tong Zhou and Tao Chen

    Article first published online : 29 JUN 2012, DOI: 10.1002/jat.2781

  18. Targeting glutamine transport to suppress melanoma cell growth

    International Journal of Cancer

    Volume 135, Issue 5, 01 September 2014, Pages: 1060–1071, Qian Wang, Kimberley A. Beaumont, Nicholas J. Otte, Josep Font, Charles G. Bailey, Michelle van Geldermalsen, Danae M. Sharp, Jessamy C. Tiffen, Renae M. Ryan, Mika Jormakka, Nikolas K. Haass, John E.J. Rasko and Jeff Holst

    Article first published online : 17 FEB 2014, DOI: 10.1002/ijc.28749

  19. Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and genomic instability

    Journal of Applied Toxicology

    Volume 33, Issue 9, September 2013, Pages: 915–923, Jie Zhao, Tao Guan, Jianhua Wang, Qian Xiang, Mingsheng Wang, Xiuwei Wang, Zhen Guan, Qiu Xie, Bo Niu and Ting Zhang

    Article first published online : 13 JUL 2012, DOI: 10.1002/jat.2769

  20. Establishment and intra-/inter-laboratory validation of a standard protocol of reactive oxygen species assay for chemical photosafety evaluation

    Journal of Applied Toxicology

    Volume 33, Issue 11, November 2013, Pages: 1241–1250, Satomi Onoue, Kazuhiro Hosoi, Shinobu Wakuri, Yumiko Iwase, Toshinobu Yamamoto, Naoko Matsuoka, Kazuichi Nakamura, Tsuguto Toda, Hironori Takagi, Naoto Osaki, Yasuhiro Matsumoto, Satoru Kawakami, Yoshiki Seto, Masashi Kato, Shizuo Yamada, Yasuo Ohno and Hajime Kojima

    Article first published online : 13 JUN 2012, DOI: 10.1002/jat.2776