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There are 2861 results for: content related to: Hybrid in silico models for drug-induced liver injury using chemical descriptors and in vitro cell-imaging information

  1. Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs

    Journal of Applied Toxicology

    Volume 36, Issue 6, June 2016, Pages: 752–768, M. José Gómez-Lechón, Laia Tolosa and M. Teresa Donato

    Version of Record online : 22 DEC 2015, DOI: 10.1002/jat.3277

  2. A modified multiparametric assay using HepaRG cells for predicting the degree of drug-induced liver injury risk

    Journal of Applied Toxicology

    Volume 37, Issue 3, March 2017, Pages: 382–390, Takafumi Tomida, Hayao Okamura, Tsuyoshi Yokoi and Yoshihiro Konno

    Version of Record online : 2 AUG 2016, DOI: 10.1002/jat.3371

  3. Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model

    Journal of Applied Toxicology

    Volume 35, Issue 2, February 2015, Pages: 152–164, Jung Woo Eun, Hyun Jin Bae, Qingyu Shen, Se Jin Park, Hyung Seok Kim, Woo Chan Shin, Hee Doo Yang, Chan Young Jin, Jueng Soo You, Hyun Joo Kang, Hoguen Kim, Young Min Ahn, Won Sang Park, Jung Young Lee and Suk Woo Nam

    Version of Record online : 18 SEP 2014, DOI: 10.1002/jat.3062

  4. Drug safety testing paradigm, current progress and future challenges: an overview

    Journal of Applied Toxicology

    Volume 34, Issue 6, June 2014, Pages: 576–594, Varun Ahuja and Sharad Sharma

    Version of Record online : 29 OCT 2013, DOI: 10.1002/jat.2935

  5. Blood transcriptomics: applications in toxicology

    Journal of Applied Toxicology

    Volume 33, Issue 11, November 2013, Pages: 1193–1202, Pius Joseph, Christina Umbright and Rajendran Sellamuthu

    Version of Record online : 1 MAR 2013, DOI: 10.1002/jat.2861

  6. Prediction of drug-induced liver injury using keratinocytes

    Journal of Applied Toxicology

    Volume 37, Issue 7, July 2017, Pages: 863–872, Rika Hirashima, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara

    Version of Record online : 31 JAN 2017, DOI: 10.1002/jat.3435

  7. The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects

    Journal of Applied Toxicology

    Volume 33, Issue 4, April 2013, Pages: 246–264, Panagiotis Zogopoulos, Ioanna Vasileiou, Efstratios Patsouris and Stamatios Theocharis

    Version of Record online : 8 JAN 2013, DOI: 10.1002/jat.2828

  8. Review: Toxicometabolomics

    Journal of Applied Toxicology

    Volume 33, Issue 12, December 2013, Pages: 1365–1383, Mounir Bouhifd, Thomas Hartung, Helena T. Hogberg, Andre Kleensang and Liang Zhao

    Version of Record online : 30 MAY 2013, DOI: 10.1002/jat.2874

  9. SAR analysis and bioactive potentials of freshwater and terrestrial cyanobacterial compounds: a review

    Journal of Applied Toxicology

    Volume 33, Issue 5, May 2013, Pages: 313–349, M. Nagarajan, V. Maruthanayagam and M. Sundararaman

    Version of Record online : 22 NOV 2012, DOI: 10.1002/jat.2833

  10. Chemoinformatics and chemical genomics: potential utility of in silico methods

    Journal of Applied Toxicology

    Volume 32, Issue 11, November 2012, Pages: 880–889, Luis G. Valerio Jr and Supratim Choudhuri

    Version of Record online : 10 AUG 2012, DOI: 10.1002/jat.2804

  11. Proteomic profiling in incubation medium of mouse, rat and human precision-cut liver slices for biomarker detection regarding acute drug-induced liver injury

    Journal of Applied Toxicology

    Volume 34, Issue 9, September 2014, Pages: 993–1001, Rachel P. L. van Swelm, Mackenzie Hadi, Coby M. M. Laarakkers, Rosalinde Masereeuw, Geny M. M. Groothuis and Frans G. M. Russel

    Version of Record online : 30 AUG 2013, DOI: 10.1002/jat.2917

  12. Chronic arsenic intoxication diagnostic score (CAsIDS)

    Journal of Applied Toxicology

    Sergio Ulhoa Dani and Gerhard Franz Walter

    Version of Record online : 31 AUG 2017, DOI: 10.1002/jat.3512

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    Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity

    Journal of Applied Toxicology

    Volume 37, Issue 1, January 2017, Pages: 23–37, Dayton M. Petibone, Waqar Majeed and Daniel A. Casciano

    Version of Record online : 29 SEP 2016, DOI: 10.1002/jat.3393

  14. Nitroaromatic compounds: Environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism

    Journal of Applied Toxicology

    Volume 34, Issue 8, August 2014, Pages: 810–824, Peter Kovacic and Ratnasamy Somanathan

    Version of Record online : 16 FEB 2014, DOI: 10.1002/jat.2980

  15. T-helper cell-mediated factors in drug-induced liver injury

    Journal of Applied Toxicology

    Volume 35, Issue 7, July 2015, Pages: 695–700, Xinzhi Wang, Luyong Zhang and Zhenzhou Jiang

    Version of Record online : 6 MAR 2015, DOI: 10.1002/jat.3115

  16. Th2 cytokine-mediated methimazole-induced acute liver injury in mice

    Journal of Applied Toxicology

    Volume 32, Issue 10, October 2012, Pages: 823–833, Masanori Kobayashi, Satonori Higuchi, Mika Ide, Satomi Nishikawa, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi

    Version of Record online : 9 MAR 2012, DOI: 10.1002/jat.2731

  17. Cellular-signaling pathways unveil the carcinogenic potential of chemicals

    Journal of Applied Toxicology

    Volume 33, Issue 6, June 2013, Pages: 399–409, Giel Hendriks, Bob van de Water, Willem Schoonen and Harry Vrieling

    Version of Record online : 22 JAN 2013, DOI: 10.1002/jat.2845

  18. Preclinical safety assessments of nano-sized constructs on cardiovascular system toxicity: A case for telemetry

    Journal of Applied Toxicology

    Volume 37, Issue 11, November 2017, Pages: 1268–1285, Hoay Yan Cheah, Lik Voon Kiew, Hong Boon Lee, Nina Japundžić-Žigon, Marίa J. Vicent, See Ziau Hoe and Lip Yong Chung

    Version of Record online : 6 FEB 2017, DOI: 10.1002/jat.3437

  19. Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

    Journal of Applied Toxicology

    Volume 35, Issue 9, September 2015, Pages: 1017–1029, Natalie Mesens, Alexander D. Crawford, Aswin Menke, Pham Duc Hung, Freddy Van Goethem, Rik Nuyts, Erik Hansen, Andre Wolterbeek, Jacky Van Gompel, Peter De Witte and Camila V. Esguerra

    Version of Record online : 6 FEB 2015, DOI: 10.1002/jat.3091

  20. Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury

    Journal of Applied Toxicology

    Volume 33, Issue 8, August 2013, Pages: 700–711, José G. Dórea, Marcelo Farina and João B. T. Rocha

    Version of Record online : 11 FEB 2013, DOI: 10.1002/jat.2855