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There are 375 results for: content related to: Long-term maintenance of HepaRG cells in serum-free conditions and application in a repeated dose study

  1. You have full text access to this OnlineOpen article
    Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes

    Hepatology Research

    Yichiro Higuchi, Kenji Kawai, Tatsuro Kanaki, Hiroshi Yamazaki, Christophe Chesné, Christiane Guguen-Guillouzo and Hiroshi Suemizu

    Version of Record online : 7 FEB 2016, DOI: 10.1111/hepr.12644

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    Hepatocyte polarization is essential for the productive entry of the hepatitis B virus


    Volume 55, Issue 2, February 2012, Pages: 373–383, Andreas Schulze, Kerry Mills, Thomas S. Weiss and Stephan Urban

    Version of Record online : 16 DEC 2011, DOI: 10.1002/hep.24707

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    Control of hepatitis B virus replication by innate response of HepaRG cells


    Volume 51, Issue 1, January 2010, Pages: 63–72, Julie Lucifora, David Durantel, Barbara Testoni, Olivier Hantz, Massimo Levrero and Fabien Zoulim

    Version of Record online : 10 AUG 2009, DOI: 10.1002/hep.23230

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    Long-term propagation of serum hepatitis C virus (HCV) with production of enveloped HCV particles in human HepaRG hepatocytes


    Volume 54, Issue 2, August 2011, Pages: 406–417, Ndiémé Ndongo-Thiam, Pascale Berthillon, Elisabeth Errazuriz, Isabelle Bordes, Sylvie De Sequeira, Christian Trépo and Marie-Anne Petit

    Version of Record online : 30 JUN 2011, DOI: 10.1002/hep.24386

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    Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells


    Volume 60, Issue 6, December 2014, Pages: 2077–2090, Hélène Dubois-Pot-Schneider, Karim Fekir, Cédric Coulouarn, Denise Glaise, Caroline Aninat, Kathleen Jarnouen, Rémy Le Guével, Takashi Kubo, Seiichi Ishida, Fabrice Morel and Anne Corlu

    Version of Record online : 29 OCT 2014, DOI: 10.1002/hep.27353

  6. MicroRNA Regulates Hepatocytic Differentiation of Progenitor Cells by Targeting YAP1


    Volume 34, Issue 5, May 2016, Pages: 1284–1296, Kwang Hwa Jung, Ryan L. McCarthy, Chong Zhou, Nadima Uprety, Michelle Craig Barton and Laura Beretta

    Version of Record online : 1 FEB 2016, DOI: 10.1002/stem.2283

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    Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor


    Volume 45, Issue 4, April 2007, Pages: 957–967, Virginie Cerec, Denise Glaise, Delphine Garnier, Serban Morosan, Bruno Turlin, Bernard Drenou, Philippe Gripon, Dina Kremsdorf, Christiane Guguen-Guillouzo and Anne Corlu

    Version of Record online : 28 MAR 2007, DOI: 10.1002/hep.21536

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    Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells


    Volume 57, Issue 4, April 2013, Pages: 1518–1529, Sébastien Anthérieu, Pamela Bachour-El Azzi, Julie Dumont, Ziad Abdel-Razzak, Christiane Guguen-Guillouzo, Bernard Fromenty, Marie-Anne Robin and André Guillouzo

    Version of Record online : 4 MAR 2013, DOI: 10.1002/hep.26160

  9. Investigation of ifosfamide nephrotoxicity induced in a liver–kidney co-culture biochip

    Biotechnology and Bioengineering

    Volume 110, Issue 2, February 2013, Pages: 597–608, Leila Choucha-Snouber, Caroline Aninat, Laurent Grsicom, Geoffrey Madalinski, Céline Brochot, Paul Emile Poleni, Florence Razan, Christiane Guguen Guillouzo, Cécile Legallais, Anne Corlu and Eric Leclerc

    Version of Record online : 28 AUG 2012, DOI: 10.1002/bit.24707

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    HepaRG cells: A human model to study mechanisms of acetaminophen hepatotoxicity


    Volume 53, Issue 3, March 2011, Pages: 974–982, Mitchell R. McGill, Hui-Min Yan, Anup Ramachandran, Gordon J. Murray, Douglas E. Rollins and Hartmut Jaeschke

    Version of Record online : 11 FEB 2011, DOI: 10.1002/hep.24132

  11. Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure

    Environmental Toxicology

    Simon Bucher, Pégah Jalili, Dounia Le Guillou, Karima Begriche, Karine Rondel, Sophie Martinais, Daniel Zalko, Anne Corlu, Marie-Anne Robin and Bernard Fromenty

    Version of Record online : 20 JUN 2016, DOI: 10.1002/tox.22301

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    Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells


    Volume 53, Issue 6, June 2011, Pages: 1895–1905, Sébastien Anthérieu, Alexandra Rogue, Bernard Fromenty, André Guillouzo and Marie-Anne Robin

    Version of Record online : 2 MAY 2011, DOI: 10.1002/hep.24290

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    Hepatitis B virus infection initiates with a large surface protein–dependent binding to heparan sulfate proteoglycans


    Volume 46, Issue 6, December 2007, Pages: 1759–1768, Andreas Schulze, Philippe Gripon and Stephan Urban

    Version of Record online : 28 NOV 2007, DOI: 10.1002/hep.21896

  14. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening

    Journal of Applied Toxicology

    Volume 35, Issue 8, August 2015, Pages: 909–917, Zenan Wang, Xiaobei Luo, Chukwuemeka Anene-Nzelu, Yu Yu, Xin Hong, Nisha Hari Singh, Lei Xia, Side Liu and Hanry Yu

    Version of Record online : 15 DEC 2014, DOI: 10.1002/jat.3090

  15. Regulation of Hepatic Drug Transporter Activity and Expression by Organochlorine Pesticides

    Journal of Biochemical and Molecular Toxicology

    Volume 28, Issue 3, March 2014, Pages: 119–128, Simon Bucher, Marc Le Vee, Elodie Jouan and Olivier Fardel

    Version of Record online : 27 NOV 2013, DOI: 10.1002/jbt.21543

  16. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes

    Basic & Clinical Pharmacology & Toxicology

    Volume 118, Issue 2, February 2016, Pages: 160–167, Benjamin L. Woolbright, Mitchell R. McGill, Huimin Yan and Hartmut Jaeschke

    Version of Record online : 13 AUG 2015, DOI: 10.1111/bcpt.12449

  17. You have full text access to this OnlineOpen article
    Human Hepatic HepaRG Cells Maintain an Organotypic Phenotype with High Intrinsic CYP450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications

    Basic & Clinical Pharmacology & Toxicology

    Leonard J. Nelson, Katie Morgan, Philipp Treskes, Kay Samuel, Catherine J. Henderson, Claire LeBled, Natalie Homer, M. Helen Grant, Peter C. Hayes and John N. Plevris

    Version of Record online : 15 JUL 2016, DOI: 10.1111/bcpt.12631

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    Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes


    Volume 58, Issue 1, July 2013, Pages: 31–42, Anja Meier, Stefan Mehrle, Thomas S. Weiss, Walter Mier and Stephan Urban

    Version of Record online : 14 MAR 2013, DOI: 10.1002/hep.26181

  19. You have full text access to this OnlineOpen article
    Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR-148a on tumor growth and phenotype and liver fibrosis


    Volume 63, Issue 3, March 2016, Pages: 864–879, Kwang Hwa Jung, Jing Zhang, Chong Zhou, Hong Shen, Mihai Gagea, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Anil K. Sood and Laura Beretta

    Version of Record online : 14 JAN 2016, DOI: 10.1002/hep.28367

  20. The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC-1 coactivator

    British Journal of Pharmacology

    Volume 173, Issue 10, May 2016, Pages: 1703–1715, Lucie Hyrsova, Tomas Smutny, Alejandro Carazo, Stefan Moravcik, Jana Mandikova, Frantisek Trejtnar, Sabine Gerbal-Chaloin and Petr Pavek

    Version of Record online : 8 APR 2016, DOI: 10.1111/bph.13472