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There are 8589 results for: content related to: Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH

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    Reversing LRP5-Dependent Osteoporosis and SOST Deficiency–Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity

    Journal of Bone and Mineral Research

    Volume 29, Issue 1, January 2014, Pages: 29–42, Ming-Kang Chang, Ina Kramer, Hansjoerg Keller, Jonathan H Gooi, Corinne Collett, David Jenkins, Seth A Ettenberg, Feng Cong, Christine Halleux and Michaela Kneissel

    Article first published online : 19 DEC 2013, DOI: 10.1002/jbmr.2059

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    N-cadherin Restrains PTH Activation of Lrp6/β-catenin Signaling and Osteoanabolic Action

    Journal of Bone and Mineral Research

    Volume 30, Issue 2, February 2015, Pages: 274–285, Leila Revollo, Jacqueline Kading, Sung Yeop Jeong, Jiemin Li, Valerie Salazar, Gabriel Mbalaviele and Roberto Civitelli

    Article first published online : 22 JAN 2015, DOI: 10.1002/jbmr.2323

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    Insights Into the Mechanisms of Sclerostin Action in Regulating Bone Mass Accrual

    Journal of Bone and Mineral Research

    Volume 29, Issue 1, January 2014, Pages: 24–28, Bart O Williams

    Article first published online : 19 DEC 2013, DOI: 10.1002/jbmr.2154

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    Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

    Journal of Bone and Mineral Research

    Volume 31, Issue 1, January 2016, Pages: 65–75, Megan M Weivoda, Ming Ruan, Christine M Hachfeld, Larry Pederson, Alan Howe, Rachel A Davey, Jeffrey D Zajac, Yasuhiro Kobayashi, Bart O Williams, Jennifer J Westendorf, Sundeep Khosla and Merry Jo Oursler

    Article first published online : 19 AUG 2015, DOI: 10.1002/jbmr.2599

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    An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: Applications in mice with bone property altering Lrp5 mutations

    Journal of Bone and Mineral Research

    Volume 28, Issue 10, October 2013, Pages: 2081–2093, Ugur M Ayturk, Christina M Jacobsen, Danos C Christodoulou, Joshua Gorham, Jonathan G Seidman, Christine E Seidman, Alexander G Robling and Matthew L Warman

    Article first published online : 18 SEP 2013, DOI: 10.1002/jbmr.1946

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    Sclerostin Regulates Release of Bone Mineral by Osteocytes by Induction of Carbonic Anhydrase 2

    Journal of Bone and Mineral Research

    Volume 28, Issue 12, December 2013, Pages: 2436–2448, Masakazu Kogawa, Asiri R Wijenayaka, Renee T Ormsby, Gethin P Thomas, Paul H Anderson, Lynda F Bonewald, David M Findlay and Gerald J Atkins

    Article first published online : 19 NOV 2013, DOI: 10.1002/jbmr.2003

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    Realizing the potential of gene-based molecular therapies in bone repair

    Journal of Bone and Mineral Research

    Volume 28, Issue 11, November 2013, Pages: 2245–2262, Laura Rose and Hasan Uludağ

    Article first published online : 18 OCT 2013, DOI: 10.1002/jbmr.1944

  8. High Bone Mass–Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

    Journal of Bone and Mineral Research

    Volume 30, Issue 10, October 2015, Pages: 1822–1830, Paul J Niziolek, Bryan T MacDonald, Rajendra Kedlaya, Minjie Zhang, Teresita Bellido, Xi He, Matthew L Warman and Alexander G Robling

    Article first published online : 22 SEP 2015, DOI: 10.1002/jbmr.2514

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    Diagnosis and Management of Osteonecrosis of the Jaw: A Systematic Review and International Consensus

    Journal of Bone and Mineral Research

    Volume 30, Issue 1, January 2015, Pages: 3–23, Aliya A Khan, Archie Morrison, David A Hanley, Dieter Felsenberg, Laurie K McCauley, Felice O'Ryan, Ian R Reid, Salvatore L Ruggiero, Akira Taguchi, Sotirios Tetradis, Nelson B Watts, Maria Luisa Brandi, Edmund Peters, Teresa Guise, Richard Eastell, Angela M Cheung, Suzanne N Morin, Basel Masri, Cyrus Cooper, Sarah L Morgan, Barbara Obermayer-Pietsch, Bente L Langdahl, Rana Al Dabagh, K. Shawn Davison, David L Kendler, George K Sándor, Robert G Josse, Mohit Bhandari, Mohamed El Rabbany, Dominique D Pierroz, Riad Sulimani, Deborah P Saunders, Jacques P Brown, Juliet Compston and on behalf of the International Task Force on Osteonecrosis of the Jaw

    Article first published online : 26 DEC 2014, DOI: 10.1002/jbmr.2405

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    A Review of Rodent Models of Type 2 Diabetic Skeletal Fragility

    Journal of Bone and Mineral Research

    Volume 29, Issue 5, May 2014, Pages: 1025–1040, Roberto J Fajardo, Lamya Karim, Virginia I Calley and Mary L Bouxsein

    Article first published online : 22 APR 2014, DOI: 10.1002/jbmr.2210

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    Regulated proteolytic processing of LRP6 results in release of its intracellular domain

    Journal of Neurochemistry

    Volume 101, Issue 2, April 2007, Pages: 517–529, Kaihong Mi and Gail V. W. Johnson

    Article first published online : 26 FEB 2007, DOI: 10.1111/j.1471-4159.2007.04447.x

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    Bone Cell Senescence: Mechanisms and Perspectives

    Journal of Bone and Mineral Research

    Volume 29, Issue 6, June 2014, Pages: 1311–1321, Pierre J Marie

    Article first published online : 19 MAY 2014, DOI: 10.1002/jbmr.2190

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    Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone

    Journal of Bone and Mineral Research

    Volume 28, Issue 9, September 2013, Pages: 1987–2000, Beth J Kirby, Yue Ma, Heather M Martin, Kerri L Buckle Favaro, Andrew C Karaplis and Christopher S Kovacs

    Article first published online : 19 AUG 2013, DOI: 10.1002/jbmr.1925

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    Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research

    Journal of Bone and Mineral Research

    Volume 29, Issue 1, January 2014, Pages: 1–23, Elizabeth Shane, David Burr, Bo Abrahamsen, Robert A Adler, Thomas D Brown, Angela M Cheung, Felicia Cosman, Jeffrey R Curtis, Richard Dell, David W Dempster, Peter R Ebeling, Thomas A Einhorn, Harry K Genant, Piet Geusens, Klaus Klaushofer, Joseph M Lane, Fergus McKiernan, Ross McKinney, Alvin Ng, Jeri Nieves, Regis O'Keefe, Socrates Papapoulos, Tet Sen Howe, Marjolein CH van der Meulen, Robert S Weinstein and Michael P Whyte

    Article first published online : 1 OCT 2013, DOI: 10.1002/jbmr.1998

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    Bone and Skeletal Muscle: Neighbors With Close Ties

    Journal of Bone and Mineral Research

    Volume 28, Issue 7, July 2013, Pages: 1509–1518, Douglas J DiGirolamo, Douglas P Kiel and Karyn A Esser

    Article first published online : 18 JUN 2013, DOI: 10.1002/jbmr.1969

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    Pregnancy-Associated Osteoporosis With a Heterozygous Deactivating LDL Receptor-Related Protein 5 (LRP5) Mutation and a Homozygous Methylenetetrahydrofolate Reductase (MTHFR) Polymorphism

    Journal of Bone and Mineral Research

    Volume 29, Issue 4, April 2014, Pages: 922–928, Fiona J Cook, Steven Mumm, Michael P Whyte and Deborah Wenkert

    Article first published online : 19 MAR 2014, DOI: 10.1002/jbmr.2095

  17. The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

    Journal of Bone and Mineral Research

    Volume 30, Issue 7, July 2015, Pages: 1175–1183, Timur A Yorgan, Stephanie Peters, Anke Jeschke, Peggy Benisch, Franz Jakob, Michael Amling and Thorsten Schinke

    Article first published online : 8 JUN 2015, DOI: 10.1002/jbmr.2461

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    Atypical Femoral Fracture in Osteoporosis Pseudoglioma Syndrome Associated with Two Novel Compound Heterozygous Mutations in LRP5

    Journal of Bone and Mineral Research

    Volume 30, Issue 4, April 2015, Pages: 615–620, Nerea Alonso, Dinesh C Soares, Eugene V McCloskey, Gregory D Summers, Stuart H Ralston and Celia L Gregson

    Article first published online : 25 MAR 2015, DOI: 10.1002/jbmr.2403

  19. Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain

    Journal of Bone and Mineral Research

    John L Hamilton, Masashi Nagao, Brett R Levine, Di Chen, Bjorn R Olsen and Hee-Jeong Im

    Article first published online : 8 APR 2016, DOI: 10.1002/jbmr.2828

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    Anti-Sclerostin Antibody Treatment in a Rat Model of Progressive Renal Osteodystrophy

    Journal of Bone and Mineral Research

    Volume 30, Issue 3, March 2015, Pages: 499–509, Sharon M Moe, Neal X Chen, Christopher L Newman, Jason M Organ, Michaela Kneissel, Ina Kramer, Vincent H Gattone II and Matthew R Allen

    Article first published online : 16 FEB 2015, DOI: 10.1002/jbmr.2372