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There are 11624 results for: content related to: Reversing LRP 5 -Dependent Osteoporosis and SOST Deficiency–Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity

  1. High Bone Mass–Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

    Journal of Bone and Mineral Research

    Volume 30, Issue 10, October 2015, Pages: 1822–1830, Paul J Niziolek, Bryan T MacDonald, Rajendra Kedlaya, Minjie Zhang, Teresita Bellido, Xi He, Matthew L Warman and Alexander G Robling

    Version of Record online : 22 SEP 2015, DOI: 10.1002/jbmr.2514

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    The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

    Journal of Bone and Mineral Research

    Volume 30, Issue 7, July 2015, Pages: 1175–1183, Timur A Yorgan, Stephanie Peters, Anke Jeschke, Peggy Benisch, Franz Jakob, Michael Amling and Thorsten Schinke

    Version of Record online : 8 JUN 2015, DOI: 10.1002/jbmr.2461

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    Insights Into the Mechanisms of Sclerostin Action in Regulating Bone Mass Accrual

    Journal of Bone and Mineral Research

    Volume 29, Issue 1, January 2014, Pages: 24–28, Bart O Williams

    Version of Record online : 19 DEC 2013, DOI: 10.1002/jbmr.2154

  4. You have full text access to this OnlineOpen article
    Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases

    Journal of Bone and Mineral Research

    Volume 31, Issue 3, March 2016, Pages: 640–649, Celia L Gregson, Lawrie Wheeler, Sarah A Hardcastle, Louise H Appleton, Kathryn A Addison, Marieke Brugmans, Graeme R Clark, Kate A Ward, Margaret Paggiosi, Mike Stone, Joegi Thomas, Rohan Agarwal, Kenneth ES Poole, Eugene McCloskey, William D Fraser, Eleanor Williams, Alex N Bullock, George Davey Smith, Matthew A Brown, Jon H Tobias and Emma L Duncan

    Version of Record online : 6 OCT 2015, DOI: 10.1002/jbmr.2706

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    Sclerostin Regulates Release of Bone Mineral by Osteocytes by Induction of Carbonic Anhydrase 2

    Journal of Bone and Mineral Research

    Volume 28, Issue 12, December 2013, Pages: 2436–2448, Masakazu Kogawa, Asiri R Wijenayaka, Renee T Ormsby, Gethin P Thomas, Paul H Anderson, Lynda F Bonewald, David M Findlay and Gerald J Atkins

    Version of Record online : 19 NOV 2013, DOI: 10.1002/jbmr.2003

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    Bone Density Ligand, Sclerostin, Directly Interacts With LRP5 but Not LRP5G171V to Modulate Wnt Activity

    Journal of Bone and Mineral Research

    Volume 21, Issue 11, November 2006, Pages: 1738–1749, Debra L Ellies, Beth Viviano, John McCarthy, Jean-Philippe Rey, Nobue Itasaki, Scott Saunders and Robb Krumlauf

    Version of Record online : 21 AUG 2006, DOI: 10.1359/jbmr.060810

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    N-cadherin Restrains PTH Activation of Lrp6/β-catenin Signaling and Osteoanabolic Action

    Journal of Bone and Mineral Research

    Volume 30, Issue 2, February 2015, Pages: 274–285, Leila Revollo, Jacqueline Kading, Sung Yeop Jeong, Jiemin Li, Valerie Salazar, Gabriel Mbalaviele and Roberto Civitelli

    Version of Record online : 22 JAN 2015, DOI: 10.1002/jbmr.2323

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    Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta

    Journal of Bone and Mineral Research

    Volume 29, Issue 10, October 2014, Pages: 2297–2306, Christina M Jacobsen, Lauren A Barber, Ugur M Ayturk, Heather J Roberts, Lauren E Deal, Marissa A Schwartz, MaryAnn Weis, David Eyre, David Zurakowski, Alexander G Robling and Matthew L Warman

    Version of Record online : 26 SEP 2014, DOI: 10.1002/jbmr.2198

  9. You have full text access to this OnlineOpen article
    An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: Applications in mice with bone property altering Lrp5 mutations

    Journal of Bone and Mineral Research

    Volume 28, Issue 10, October 2013, Pages: 2081–2093, Ugur M Ayturk, Christina M Jacobsen, Danos C Christodoulou, Joshua Gorham, Jonathan G Seidman, Christine E Seidman, Alexander G Robling and Matthew L Warman

    Version of Record online : 18 SEP 2013, DOI: 10.1002/jbmr.1946

  10. Lrp5 and Lrp6 play compensatory roles in mouse intestinal development

    Journal of Cellular Biochemistry

    Volume 113, Issue 1, January 2012, Pages: 31–38, Zhendong Zhong, Jacob J. Baker, Cassandra R. Zylstra-Diegel and Bart O. Williams

    Version of Record online : 9 DEC 2011, DOI: 10.1002/jcb.23324

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    Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH

    Journal of Bone and Mineral Research

    Volume 28, Issue 10, October 2013, Pages: 2094–2108, Changjun Li, Qiujuan Xing, Bing Yu, Hui Xie, Weishan Wang, Chenhui Shi, Janet L Crane, Xu Cao and Mei Wan

    Version of Record online : 18 SEP 2013, DOI: 10.1002/jbmr.1962

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    Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6

    Journal of Bone and Mineral Research

    Volume 19, Issue 12, December 2004, Pages: 2033–2040, Sheri L Holmen, Troy A Giambernardi, Cassandra R Zylstra, Bree D Buckner-Berghuis, James H Resau, J Fred Hess, Vaida Glatt, Mary L Bouxsein, Minrong Ai, Matthew L Warman and Bart O Williams

    Version of Record online : 13 SEP 2004, DOI: 10.1359/jbmr.040907

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    Common Genetic Variation of the Low-Density Lipoprotein Receptor-Related Protein 5 and 6 Genes Determines Fracture Risk in Elderly White Men

    Journal of Bone and Mineral Research

    Volume 21, Issue 1, January 2006, Pages: 141–150, Joyce BJ van Meurs, Fernando Rivadeneira, Mila Jhamai, Wendy Hugens, Albert Hofman, Johannes PTM van Leeuwen, Huibert AP Pols and André G Uitterlinden

    Version of Record online : 6 SEP 2005, DOI: 10.1359/JBMR.050904

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    LRP5, serotonin, and bone: Complexity, contradictions, and conundrums

    Journal of Bone and Mineral Research

    Volume 26, Issue 9, September 2011, Pages: 1997–2001, David Goltzman

    Version of Record online : 19 AUG 2011, DOI: 10.1002/jbmr.462

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    Lipoprotein receptor–related protein 6 is required for parathyroid hormone–induced Sost suppression

    Annals of the New York Academy of Sciences

    Volume 1364, Issue 1, January 2016, Pages: 62–73, Changjun Li, Weishan Wang, Liang Xie, Xianghang Luo, Xu Cao and Mei Wan

    Version of Record online : 2 APR 2015, DOI: 10.1111/nyas.12750

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    Lrp6 Hypomorphic Mutation Affects Bone Mass Through Bone Resorption in Mice and Impairs Interaction With Mesd

    Journal of Bone and Mineral Research

    Volume 23, Issue 10, October 2008, Pages: 1661–1671, Takuo Kubota, Toshimi Michigami, Naoko Sakaguchi, Chikara Kokubu, Akira Suzuki, Noriyuki Namba, Norio Sakai, Shigeo Nakajima, Kenji Imai and Keiichi Ozono

    Version of Record online : 19 MAY 2008, DOI: 10.1359/jbmr.080512

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    Atypical Femoral Fracture in Osteoporosis Pseudoglioma Syndrome Associated with Two Novel Compound Heterozygous Mutations in LRP5

    Journal of Bone and Mineral Research

    Volume 30, Issue 4, April 2015, Pages: 615–620, Nerea Alonso, Dinesh C Soares, Eugene V McCloskey, Gregory D Summers, Stuart H Ralston and Celia L Gregson

    Version of Record online : 25 MAR 2015, DOI: 10.1002/jbmr.2403

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    LRP5 deficiency down-regulates Wnt signalling and promotes aortic lipid infiltration in hypercholesterolaemic mice

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 4, April 2015, Pages: 770–777, Maria Borrell-Pagès, July Carolina Romero and Lina Badimon

    Version of Record online : 5 FEB 2015, DOI: 10.1111/jcmm.12396

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    ASBMR 30th Annual Meeting 1001–1300

    Journal of Bone and Mineral Research

    Volume 23, Issue S1, 13 August 2008, Pages: S2–S85,

    Version of Record online : 16 JUN 2011, DOI: 10.1002/jbmr.5650231302

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    The WNT system: background and its role in bone

    Journal of Internal Medicine

    Volume 277, Issue 6, June 2015, Pages: 630–649, U. H. Lerner and C. Ohlsson

    Version of Record online : 25 MAY 2015, DOI: 10.1111/joim.12368