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There are 17773 results for: content related to: HIFs, angiogenesis, and cancer

  1. Hypoxia-inducible factors – regulation, role and comparative aspects in tumourigenesis

    Veterinary and Comparative Oncology

    Volume 9, Issue 1, March 2011, Pages: 16–37, A. E. Hansen, A. T. Kristensen, I. Law, J. T. Jørgensen and S. A. Engelholm

    Article first published online : 16 AUG 2010, DOI: 10.1111/j.1476-5829.2010.00233.x

  2. Oxygen homeostasis

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 2, Issue 3, May/June 2010, Pages: 336–361, Gregg L. Semenza

    Article first published online : 2 NOV 2009, DOI: 10.1002/wsbm.69

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    Normoxic Expression of Hypoxia-Inducible Factor 1 in Rat Leydig Cells In Vivo and In Vitro

    Journal of Andrology

    Volume 32, Issue 3, May-June 2011, Pages: 307–323, Dr M. A. Palladino, P. R. Pirlamarla, J. McNamara, C. M. Sottas, N. Korah, M. P. Hardy, D. B. Hales and L. Hermo

    Article first published online : 2 JAN 2013, DOI: 10.2164/jandrol.110.011494

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    Concise Review: Genetic Dissection of Hypoxia Signaling Pathways in Normal and Leukemic Stem Cells

    STEM CELLS

    Volume 32, Issue 6, June 2014, Pages: 1390–1397, Deniz Gezer, Milica Vukovic, Tomoyoshi Soga, Patrick J. Pollard and Kamil R. Kranc

    Article first published online : 23 MAY 2014, DOI: 10.1002/stem.1657

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    Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice

    Hepatology

    Volume 53, Issue 5, May 2011, Pages: 1526–1537, Bharath Nath, Ivan Levin, Timea Csak, Jan Petrasek, Christian Mueller, Karen Kodys, Donna Catalano, Pranoti Mandrekar and Gyongyi Szabo

    Article first published online : 22 APR 2011, DOI: 10.1002/hep.24256

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    Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: Role of Hsp70 in HIF-1α degradation

    Journal of Bone and Mineral Research

    Volume 27, Issue 5, May 2012, Pages: 1106–1117, Shilpa S Gogate, Nobuyuki Fujita, Renata Skubutyte, Irving M Shapiro and Makarand V Risbud

    Article first published online : 18 APR 2012, DOI: 10.1002/jbmr.1571

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    Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein–protein interaction

    Protein Science

    Volume 21, Issue 12, December 2012, Pages: 1885–1896, Rosa Cardoso, Robert Love, Carol L. Nilsson, Simon Bergqvist, Dawn Nowlin, Jiangli Yan, Kevin K.-C. Liu, Jing Zhu, Ping Chen, Ya-Li Deng, H. Jane Dyson, Michael J. Greig and Alexei Brooun

    Article first published online : 9 NOV 2012, DOI: 10.1002/pro.2172

  8. TNFα induces expression of HIF-1α mRNA and protein but inhibits hypoxic stimulation of HIF-1 transcriptional activity in airway smooth muscle cells

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1745–1753, Stamatina Tsapournioti, Ilias Mylonis, Apostolia Hatziefthimiou, Maria G. Ioannou, Rodopi Stamatiou, Georgios K. Koukoulis, George Simos, Paschalis-Adam Molyvdas and Efrosyni Paraskeva

    Article first published online : 18 APR 2013, DOI: 10.1002/jcp.24331

  9. Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms

    Liver International

    Volume 30, Issue 5, May 2010, Pages: 669–682, Bryan L. Copple

    Article first published online : 15 FEB 2010, DOI: 10.1111/j.1478-3231.2010.02205.x

  10. HIF-1 Inhibitors for Cancer Therapy

    Tumor Microenvironment

    Annamaria Rapisarda, Giovanni Melillo, Pages: 377–400, 2010

    Published Online : 30 AUG 2010, DOI: 10.1002/9780470669891.ch17

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    Prolyl hydroxylase domain enzyme 2 is the major player in regulating hypoxic responses in rheumatoid arthritis

    Arthritis & Rheumatism

    Volume 64, Issue 9, September 2012, Pages: 2856–2867, Barbara Muz, Helene Larsen, Leigh Madden, Serafim Kiriakidis and Ewa M. Paleolog

    Article first published online : 27 AUG 2012, DOI: 10.1002/art.34479

  12. Recent agents targeting HIF-1α for cancer therapy

    Journal of Cellular Biochemistry

    Volume 114, Issue 3, March 2013, Pages: 498–509, Yaozhong Hu, Jing Liu and He Huang

    Article first published online : 22 JAN 2013, DOI: 10.1002/jcb.24390

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    Hypoxia-Inducible Factor-1α Is Constitutively Expressed in Murine Leydig Cells and Regulates 3β-Hydroxysteroid Dehydrogenase Type 1 Promoter Activity

    Journal of Andrology

    Volume 30, Issue 2, March-April 2009, Pages: 146–156, Jeffrey J. Lysiak, Jennifer L. Kirby, Jacques J. Tremblay, Robin I. Woodson, Michael A. Reardon, Lisa A. Palmer and Terry T. Turner

    Article first published online : 2 JAN 2013, DOI: 10.2164/jandrol.108.006155

  14. Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic Kupffer cells

    Hepatology Research

    Volume 40, Issue 5, May 2010, Pages: 530–539, Bryan L. Copple, Shan Bai and Jeon-Ok Moon

    Article first published online : 14 APR 2010, DOI: 10.1111/j.1872-034X.2010.00635.x

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    Hypoxia Promotes the Production and Inhibits the Destruction of Human Articular Cartilage

    Arthritis & Rheumatism

    Volume 65, Issue 5, May 2013, Pages: 1302–1312, Brendan L. Thoms, Katarzyna A. Dudek, Jérôme E. Lafont and Christopher L. Murphy

    Article first published online : 23 APR 2013, DOI: 10.1002/art.37867

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    Constitutive Expression of HIF-1α and HIF-2α in Bone Marrow Stromal Cells Differentially Promotes Their Proangiogenic Properties

    STEM CELLS

    Volume 26, Issue 10, October 2008, Pages: 2634–2643, Jeremy Ben-Shoshan, Shulamit Schwartz, Galia Luboshits, Sofia Maysel-Auslender, Aya Barzelay, Sylvie Polak-Charcon, Eldad Tzahor, Iris Barshack, Adiel Barak, Hani Levkovitch-Verbin, Gad Keren and Jacob George

    Article first published online : 7 AUG 2008, DOI: 10.1634/stemcells.2008-0369

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    HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc

    Journal of Bone and Mineral Research

    Volume 27, Issue 2, February 2012, Pages: 401–412, Nobuyuki Fujita, Kazuhiro Chiba, Irving M Shapiro and Makarand V Risbud

    Article first published online : 23 JAN 2012, DOI: 10.1002/jbmr.538

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    VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival

    Journal of Bone and Mineral Research

    Volume 27, Issue 3, March 2012, Pages: 596–609, Christa Maes, Elisa Araldi, Katharina Haigh, Richa Khatri, Riet Van Looveren, Amato J Giaccia, Jody J Haigh, Geert Carmeliet and Ernestina Schipani

    Article first published online : 21 FEB 2012, DOI: 10.1002/jbmr.1487

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    Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1–dependent apoptotic pathway

    Hepatology

    Volume 57, Issue 3, March 2013, Pages: 1088–1097, Hai-Xiang Sun, Yang Xu, Xin-Rong Yang, Wei-Min Wang, Haibo Bai, Ruo-Yu Shi, Suresh K. Nayar, Ranjan P. Devbhandari, Yi-zhou He, Qin-Feng Zhu, Yun-Fan Sun, Bo Hu, Mehtab Khan, Robert A. Anders and Jia Fan

    Article first published online : 7 FEB 2013, DOI: 10.1002/hep.26188

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    Cell-specific blood–brain barrier regulation in health and disease: a focus on hypoxia

    British Journal of Pharmacology

    Volume 171, Issue 5, March 2014, Pages: 1210–1230, S Engelhardt, S Patkar and O O Ogunshola

    Article first published online : 27 FEB 2014, DOI: 10.1111/bph.12489