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There are 28731 results for: content related to: Calculation of binding free energies of inhibitors to plasmepsin II

  1. Plasmepsins as potential targets for new antimalarial therapy

    Medicinal Research Reviews

    Volume 26, Issue 5, September 2006, Pages: 626–666, Karolina Ersmark, Bertil Samuelsson and Anders Hallberg

    Version of Record online : 12 JUL 2006, DOI: 10.1002/med.20082

  2. You have full text access to this OnlineOpen article
    Role of Plasmepsin V in Export of Diverse Protein Families from the Plasmodium falciparum Exportome

    Traffic

    Volume 14, Issue 5, May 2013, Pages: 532–550, Justin A. Boddey, Teresa G. Carvalho, Anthony N. Hodder, Tobias J. Sargeant, Brad E. Sleebs, Danushka Marapana, Sash Lopaticki, Thomas Nebl and Alan F. Cowman

    Version of Record online : 27 FEB 2013, DOI: 10.1111/tra.12053

  3. An Ab Initio Method for Designing Multi-Target Specific Pharmacophores using Complementary Interaction Field of Aspartic Proteases

    Molecular Informatics

    Volume 34, Issue 6-7, June 2015, Pages: 380–393, Rama Kaalia, Amit Kumar, Ashwin Srinivasan and Indira Ghosh

    Version of Record online : 20 MAR 2015, DOI: 10.1002/minf.201400157

  4. You have free access to this content
    Expression and Characterisation of Plasmepsin I from Plasmodium falciparum

    European Journal of Biochemistry

    Volume 244, Issue 2, March 1997, Pages: 552–560, Richard P. Moon, Lorraine Tyas, Ulrich Certa, Katharina Rupp, Daniel Bur, Catherine Jacquet, Hugues Matile, Hansruedi Loetscher, Fiona Grueninger-Leitch, John Kay, Ben M. Dunn, Colin Berry and Robert G. Ridley

    Version of Record online : 16 JUL 2004, DOI: 10.1111/j.1432-1033.1997.00552.x

  5. Flap flexibility amongst plasmepsins I, II, III, IV, and V: Sequence, structural, and molecular dynamics analyses

    Proteins: Structure, Function, and Bioinformatics

    Volume 83, Issue 9, September 2015, Pages: 1693–1705, Lara McGillewie and Mahmoud E. Soliman

    Version of Record online : 1 AUG 2015, DOI: 10.1002/prot.24855

  6. You have free access to this content
    Activity and inhibition of plasmepsin IV, a new aspartic proteinase from the malaria parasite, Plasmodium falciparum

    FEBS Letters

    Volume 513, Issue 2-3, February 27, 2002, Pages: 159–162, David M Wyatt and Colin Berry

    Version of Record online : 18 JAN 2002, DOI: 10.1016/S0014-5793(02)02241-X

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    Naturally-occurring and recombinant forms of the aspartic proteinases plasmepsins I and II from the human malaria parasite Plasmodium f alciparum

    FEBS Letters

    Volume 454, Issue 3, July 09, 1999, Pages: 210–214,

    Version of Record online : 9 JUL 1999, DOI: 10.1016/S0014-5793(99)00805-4

  8. You have free access to this content
    Insight into Selectivity of Peptidomimetic Inhibitors with Modified Statine Core for Plasmepsin II of Plasmodium falciparum over Human Cathepsin D

    Chemical Biology & Drug Design

    Volume 79, Issue 4, April 2012, Pages: 411–430, Brice Dali, Melalie Keita, Eugene Megnassan, Vladimir Frecer and Stanislav Miertus

    Version of Record online : 21 MAR 2012, DOI: 10.1111/j.1747-0285.2011.01276.x

  9. You have full text access to this OnlineOpen article
    The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell

    Molecular Microbiology

    Volume 87, Issue 4, February 2013, Pages: 835–850, Sarah J. Tarr, Adam Cryar, Konstantinos Thalassinos, Kasturi Haldar and Andrew R. Osborne

    Version of Record online : 21 JAN 2013, DOI: 10.1111/mmi.12133

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    Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function

    Molecular Microbiology

    Volume 65, Issue 1, July 2007, Pages: 64–75, J. Alfredo Bonilla, Tonya D. Bonilla, Charles A. Yowell, Hisashi Fujioka and John B. Dame

    Version of Record online : 13 MAY 2007, DOI: 10.1111/j.1365-2958.2007.05768.x

  11. Expression, Purification, and Characterization of Aspartic Endopeptidases: Plasmodium Plasmepsins and “Short” Recombinant Human Pseudocathepsin

    Unit

    Current Protocols in Protein Science

    21:21.14.1–21.14.24

    Bret B. Beyer, Nathan E. Goldfarb and Ben M. Dunn

    Published Online : 1 AUG 2004, DOI: 10.1002/0471140864.ps2114s32

  12. Plasmepsins Inhibitors as Potential Drugs against Malaria: Starving the Parasite

    Aspartic Acid Proteases as Therapeutic Targets

    Arun K. Ghosh, Pages: 549–571, 2011

    Published Online : 4 APR 2011, DOI: 10.1002/9783527630943.ch19

  13. Design and Discovery of Plasmepsin II Inhibitors Using an Automated Workflow on Large-Scale Grids

    ChemMedChem

    Volume 4, Issue 7, July 6, 2009, Pages: 1164–1173, Gianluca Degliesposti, Vinod Kasam, Ana Da Costa, Hee-Kyoung Kang, Nahyun Kim, Do-Won Kim, Vincent Breton, Doman Kim and Giulio Rastelli

    Version of Record online : 12 MAY 2009, DOI: 10.1002/cmdc.200900111

  14. Antimalarials

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    David C. Smithson, W. Armand Guiguemde and R. Kiplin Guy

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc234

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    The aspartic proteinase from the rodent parasite Plasmodium berghei as a potential model for plasmepsins from the human malaria parasite, Plasmodium falciparum

    FEBS Letters

    Volume 463, Issue 1-2, December 10, 1999, Pages: 43–48, Michelle J. Humphreys, Richard P. Moon, Annette Klinder, Sylvia D. Fowler, Katharina Rupp, Daniel Bur, Robert G. Ridley and Colin Berry

    Version of Record online : 7 DEC 1999, DOI: 10.1016/S0014-5793(99)01597-5

  16. Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations

    Proteins: Structure, Function, and Bioinformatics

    Volume 73, Issue 2, 1 November 2008, Pages: 440–457, Pedro A. Valiente, Paulo R. Batista, Amaury Pupo, Tirso Pons, Alfonso Valencia and Pedro G. Pascutti

    Version of Record online : 28 APR 2008, DOI: 10.1002/prot.22068

  17. The Plasmepsin Family as Antimalarial Drug Targets

    Aspartic Acid Proteases as Therapeutic Targets

    Adam J. Ruben, Yoshiaki Kiso, Ernesto Freire, Pages: 511–547, 2011

    Published Online : 4 APR 2011, DOI: 10.1002/9783527630943.ch18

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    Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor

    FEBS Letters

    Volume 580, Issue 25, October 30, 2006, Pages: 5910–5916, Hugo Gutiérrez-de-Terán, Martin Nervall, Ben M. Dunn, Jose C. Clemente and Johan Åqvist

    Version of Record online : 5 OCT 2006, DOI: 10.1016/j.febslet.2006.09.057

  19. On the orientation of the catalytic dyad in aspartic proteases

    Proteins: Structure, Function, and Bioinformatics

    Volume 78, Issue 6, 1 May 2010, Pages: 1575–1582, Ran Friedman and Amedeo Caflisch

    Version of Record online : 21 DEC 2009, DOI: 10.1002/prot.22674

  20. Haemoglobin Degradation and Haem Polymerization as Antimalarial Drug Targets

    Journal of Pharmacy and Pharmacology

    Volume 49, Issue S2, April 1997, Pages: 43–48, ROBERT G. RIDLEY

    Version of Record online : 12 APR 2011, DOI: 10.1111/j.2042-7158.1997.tb06159.x