Search Results

There are 3199 results for: content related to: Integration of biostatistics and pharmacometrics computing platforms for efficient and reproducible PK/PD analysis: A case study

  1. You have free access to this content
    Challenges and considerations for development of therapeutic proteins in pediatric patients

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S103–S115, Yi Zhang, Xiaohui Wei, Gaurav Bajaj, Jeffrey S. Barrett, Bernd Meibohm, Amita Joshi and Manish Gupta

    Article first published online : 23 FEB 2015, DOI: 10.1002/jcph.382

  2. You have full text access to this OnlineOpen article
    Reporting guidelines for population pharmacokinetic analyses

    The Journal of Clinical Pharmacology

    Volume 55, Issue 8, August 2015, Pages: 875–887, Kevin Dykstra, Nitin Mehrotra, Christoffer Wenzel Tornøe, Helen Kastrissios, Bela Patel, Nidal Al-Huniti, Pravin Jadhav, Yaning Wang and Wonkyung Byon

    Article first published online : 6 JUL 2015, DOI: 10.1002/jcph.532

  3. You have free access to this content
    Modeling and simulation analysis of the relationship between lesion recurrence on brain images and clinical recurrence in patients with ischemic stroke

    The Journal of Clinical Pharmacology

    Volume 55, Issue 4, April 2015, Pages: 458–466, Hyeong-Seok Lim and Kyun-Seop Bae

    Article first published online : 5 DEC 2014, DOI: 10.1002/jcph.427

  4. Pharmacometrics: A Multidisciplinary Field to Facilitate Critical Thinking in Drug Development and Translational Research Settings

    The Journal of Clinical Pharmacology

    Volume 48, Issue 5, May 2008, Pages: 632–649, Dr Jeffrey S. Barrett, Dr Michael J. Fossler, Mr K. David Cadieu and Dr Marc R. Gastonguay

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270008315318

  5. You have free access to this content
    Dashboard systems: Pharmacokinetic/pharmacodynamic mediated dose optimization for monoclonal antibodies

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S51–S59, Diane R. Mould and Marla C. Dubinsky

    Article first published online : 23 FEB 2015, DOI: 10.1002/jcph.370

  6. Population exposure–response model to support dosing evaluation of ixekizumab in patients with chronic plaque psoriasis

    The Journal of Clinical Pharmacology

    Volume 54, Issue 10, October 2014, Pages: 1117–1124, Lai-San Tham, Cheng-Cai Tang, Siak-Leng Choi, Julie H. Satterwhite, Gregory S. Cameron and Subhashis Banerjee

    Article first published online : 23 APR 2014, DOI: 10.1002/jcph.312

  7. Population pharmacokinetics of phenytoin in critically ill children

    The Journal of Clinical Pharmacology

    Volume 55, Issue 3, March 2015, Pages: 355–364, Stefanie Hennig, Ross Norris, Quyen Tu, Karin van Breda, Kate Riney, Kelly Foster, Bruce Lister and Bruce Charles

    Article first published online : 4 DEC 2014, DOI: 10.1002/jcph.417

  8. Quantitative clinical pharmacology for size and age scaling in pediatric drug development: A systematic review

    The Journal of Clinical Pharmacology

    Tanay S. Samant, Naveen Mangal, Viera Lukacova and Stephan Schmidt

    Article first published online : 15 JUL 2015, DOI: 10.1002/jcph.555

  9. Estimation of tenofovir's population pharmacokinetic parameters without reliable dosing histories and application to tracing dosing history using simulation strategies

    The Journal of Clinical Pharmacology

    Volume 54, Issue 2, February 2014, Pages: 150–160, Ayyappa Chaturvedula, Michael J. Fossler and Craig W. Hendrix

    Article first published online : 30 NOV 2013, DOI: 10.1002/jcph.221

  10. You have full text access to this OnlineOpen article
    Interactive Pharmacometric Applications Using R and the Shiny Package

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 4, Issue 3, March 2015, Pages: 146–159, J Wojciechowski, AM Hopkins and RN Upton

    Article first published online : 18 MAR 2015, DOI: 10.1002/psp4.21

  11. Pharmacometrics-guided drug development of antihyperhidrosis agents

    The Journal of Clinical Pharmacology

    Shailly Mehrotra, Virginia D. Schmith, Teodora Pene Dumitrescu and Jogarao Gobburu

    Article first published online : 18 JUN 2015, DOI: 10.1002/jcph.536

  12. You have free access to this content
    Drug-Induced Liver Injury: The Role of Drug Metabolism and Transport

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 463–474, Alberto Corsini and Michele Bortolini

    Article first published online : 22 FEB 2013, DOI: 10.1002/jcph.23

  13. Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use

    The Journal of Clinical Pharmacology

    Volume 53, Issue 8, August 2013, Pages: 787–811, Zhen Zhang, Tai-Ning Lam and Zhong Zuo

    Article first published online : 16 MAY 2013, DOI: 10.1002/jcph.96

  14. You have free access to this content
    Population dose-response analysis of daily seizure count following vigabatrin therapy in adult and pediatric patients with refractory complex partial seizures

    The Journal of Clinical Pharmacology

    Volume 55, Issue 1, January 2015, Pages: 81–92, Jace C. Nielsen, Matthew M. Hutmacher, David L. Wesche, Dwain Tolbert, Mahlaqa Patel and Kenneth G. Kowalski

    Article first published online : 12 SEP 2014, DOI: 10.1002/jcph.378

  15. Model-Based Drug Development Survey Finds Pharmacometrics Impacting Decision Making in the Pharmaceutical Industry

    The Journal of Clinical Pharmacology

    Volume 50, Issue S9, September 2010, Pages: 20S–30S, Dr Julie A. Stone, Dr Christopher Banfield, Dr Marc Pfister, Dr Stacey Tannenbaum, Dr Sandy Allerheiligen, Dr Jeffrey D. Wetherington, Dr Rajesh Krishna and Dr Dennis M. Grasela

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010377628

  16. Exodus of clinical pharmacologists and pharmacometricians from academia—Who is to blame? A policy statement from the American College of Clinical Pharmacology

    The Journal of Clinical Pharmacology

    Volume 55, Issue 9, September 2015, Pages: 955–956, Vijay V. Upreti and for the Public Policy Committee of the American College of Clinical Pharmacology

    Article first published online : 2 JUL 2015, DOI: 10.1002/jcph.542

  17. Dose selection for the investigational anticancer agent alisertib (MLN8237): Pharmacokinetics, pharmacodynamics, and exposure–safety relationships

    The Journal of Clinical Pharmacology

    Volume 55, Issue 3, March 2015, Pages: 336–347, Karthik Venkatakrishnan, Xiaofei Zhou, Jeffrey Ecsedy, Diane R. Mould, Hua Liu, Hadi Danaee, Howard Fingert, Robert Kleinfield and Ashley Milton

    Article first published online : 18 NOV 2014, DOI: 10.1002/jcph.410

  18. Predicting neonatal pharmacokinetics from prior data using population pharmacokinetic modeling

    The Journal of Clinical Pharmacology

    Jian Wang, Andrea N. Edginton, Debbie Avant and Gilbert J. Burckart

    Article first published online : 9 JUN 2015, DOI: 10.1002/jcph.524

  19. You have full text access to this OnlineOpen article
    Population pharmacokinetics of tenofovir and tenofovir-diphosphate in healthy women

    The Journal of Clinical Pharmacology

    Volume 55, Issue 6, June 2015, Pages: 629–638, Rebecca N. Burns, Craig W. Hendrix and Ayyappa Chaturvedula

    Article first published online : 4 FEB 2015, DOI: 10.1002/jcph.461

  20. You have free access to this content
    Beyond peptides and mAbs—current status and future perspectives for biotherapeutics with novel constructs

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S4–S20, Dalal AlDeghaither, Brandon G. Smaglo and Louis M. Weiner

    Article first published online : 23 FEB 2015, DOI: 10.1002/jcph.407