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There are 26666 results for: content related to: Anti-IL21 receptor monoclonal antibody (ATR-107): Safety, pharmacokinetics, and pharmacodynamic evaluation in healthy volunteers: A phase I, first-in-human study

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    Contribution of enhanced engagement of antigen presentation machinery to the clinical immunogenicity of a human interleukin (IL)-21 receptor-blocking therapeutic antibody

    Clinical & Experimental Immunology

    Volume 183, Issue 1, January 2016, Pages: 102–113, L. Xue, T. Hickling, R. Song, J. Nowak and B. Rup

    Version of Record online : 5 NOV 2015, DOI: 10.1111/cei.12711

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    IL-21: roles in immunopathology and cancer therapy

    Tissue Antigens

    Volume 74, Issue 6, December 2009, Pages: 467–479, H. Søndergaard and K. Skak

    Version of Record online : 21 OCT 2009, DOI: 10.1111/j.1399-0039.2009.01382.x

  3. Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates

    The Journal of Clinical Pharmacology

    Volume 56, Issue 8, August 2016, Pages: 909–935, Mélanie Wilbaux, Aline Fuchs, Janko Samardzic, Frédérique Rodieux, Chantal Csajka, Karel Allegaert, Johannes N. van den Anker and Marc Pfister

    Version of Record online : 31 MAR 2016, DOI: 10.1002/jcph.705

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    Interleukin-21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model

    Arthritis & Rheumatology

    Volume 67, Issue 10, October 2015, Pages: 2723–2731, Ming Zhang, Gang Yu, Brian Chan, Joshua T. Pearson, Palaniswami Rathanaswami, John Delaney, Ai Ching Lim, John Babcook, Hailing Hsu and Marc A. Gavin

    Version of Record online : 23 SEP 2015, DOI: 10.1002/art.39233

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    Drug-Induced Liver Injury: The Role of Drug Metabolism and Transport

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 463–474, Alberto Corsini and Michele Bortolini

    Version of Record online : 22 FEB 2013, DOI: 10.1002/jcph.23

  6. Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use

    The Journal of Clinical Pharmacology

    Volume 53, Issue 8, August 2013, Pages: 787–811, Zhen Zhang, Tai-Ning Lam and Zhong Zuo

    Version of Record online : 16 MAY 2013, DOI: 10.1002/jcph.96

  7. A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis

    The Journal of Clinical Pharmacology

    Anushka Naidoo, Kogieleum Naidoo, Helen McIlleron, Sabiha Essack and Nesri Padayatchi

    Version of Record online : 24 JUL 2017, DOI: 10.1002/jcph.968

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    PCSK9 Inhibition With Monoclonal Antibodies: Modern Management of Hypercholesterolemia

    The Journal of Clinical Pharmacology

    Volume 57, Issue 1, January 2017, Pages: 7–32, Matthew K. Ito and Raul D. Santos

    Version of Record online : 21 JUN 2016, DOI: 10.1002/jcph.766

  9. Beyond peptides and mAbs—current status and future perspectives for biotherapeutics with novel constructs

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S4–S20, Dalal AlDeghaither, Brandon G. Smaglo and Louis M. Weiner

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.407

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    Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S173–S192, Frédérique Rodieux, Verena Gotta, Marc Pfister and Johannes N. van den Anker

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.721

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    Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S40–S58, Cheynne McLean, Aze Wilson and Richard B. Kim

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.691

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    Evaluation of Proposed In Vivo Probe Substrates and Inhibitors for Phenotyping Transporter Activity in Humans

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S82–S98, Jeremiah D. Momper, Shirley M. Tsunoda and Joseph D. Ma

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.736

  13. Enzyme- and transporter-mediated beverage–drug interactions: An update on fruit juices and green tea

    The Journal of Clinical Pharmacology

    Volume 55, Issue 12, December 2015, Pages: 1313–1331, Guohua An, Jatinder Kaur Mukker, Hartmut Derendorf and Reginald F. Frye

    Version of Record online : 30 JUL 2015, DOI: 10.1002/jcph.563

  14. Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling

    The Journal of Clinical Pharmacology

    Volume 56, Issue 3, March 2016, Pages: 266–283, Vijay V. Upreti and Jan L. Wahlstrom

    Version of Record online : 9 OCT 2015, DOI: 10.1002/jcph.585

  15. Stem cell state and the epithelial-to-mesenchymal transition: Implications for cancer therapy

    The Journal of Clinical Pharmacology

    Volume 55, Issue 6, June 2015, Pages: 603–619, Vera S. Donnenberg and Albert D. Donnenberg

    Version of Record online : 7 APR 2015, DOI: 10.1002/jcph.486

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    Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis

    Arthritis & Rheumatism

    Volume 50, Issue 5, May 2004, Pages: 1468–1476, Astrid Jüngel, Jörg H. W. Distler, Mariola Kurowska-Stolarska, Christian A. Seemayer, Reinhart Seibl, Adrian Forster, Beat A. Michel, Renate E. Gay, Frank Emmrich, Steffen Gay and Oliver Distler

    Version of Record online : 6 MAY 2004, DOI: 10.1002/art.20218

  17. Seasonal influenza vaccination and technologies

    The Journal of Clinical Pharmacology

    Volume 54, Issue 7, July 2014, Pages: 719–731, Anne N. Nafziger and David S. Pratt

    Version of Record online : 5 APR 2014, DOI: 10.1002/jcph.299

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    The Role of Transporters in the Toxicity of Chemotherapeutic Drugs: Focus on Transporters for Organic Cations

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S157–S172, Anna Hucke and Giuliano Ciarimboli

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.706

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    Effect of Disease Pathologies on Transporter Expression and Function

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S205–S221, Amandla Atilano-Roque, Gavriel Roda, Uma Fogueri, Jennifer J. Kiser and Melanie S. Joy

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.768

  20. Clinical pharmacology of bispecific antibody constructs

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S21–S28, Chetan Rathi and Bernd Meibohm

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.445