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There are 37541 results for: content related to: Single-dose pharmacokinetics and glucodynamics of the novel, long-acting basal insulin LY2605541 in healthy subjects

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    Approaches to intravenous clinical pharmacokinetics: Recent developments with isotopic microtracers

    The Journal of Clinical Pharmacology

    Volume 56, Issue 1, January 2016, Pages: 11–23, Graham Lappin

    Version of Record online : 1 SEP 2015, DOI: 10.1002/jcph.569

  2. Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects

    The Journal of Clinical Pharmacology

    Volume 54, Issue 9, September 2014, Pages: 968–978, Stephen L. Lowe, Conrad J. Wong, Jennifer Witcher, Celedon R. Gonzales, Gemma L. Dickinson, Robert L. Bell, Linda Rorick-Kehn, MaryAnn Weller, Randall R. Stoltz, Jane Royalty and Sitra Tauscher-Wisniewski

    Version of Record online : 26 MAR 2014, DOI: 10.1002/jcph.286

  3. Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates

    The Journal of Clinical Pharmacology

    Mélanie Wilbaux, Aline Fuchs, Janko Samardzic, Frédérique Rodieux, Chantal Csajka, Karel Allegaert, Johannes N. van den Anker and Marc Pfister

    Version of Record online : 31 MAR 2016, DOI: 10.1002/jcph.705

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    Drug-Induced Liver Injury: The Role of Drug Metabolism and Transport

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 463–474, Alberto Corsini and Michele Bortolini

    Version of Record online : 22 FEB 2013, DOI: 10.1002/jcph.23

  5. Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use

    The Journal of Clinical Pharmacology

    Volume 53, Issue 8, August 2013, Pages: 787–811, Zhen Zhang, Tai-Ning Lam and Zhong Zuo

    Version of Record online : 16 MAY 2013, DOI: 10.1002/jcph.96

  6. Beyond peptides and mAbs—current status and future perspectives for biotherapeutics with novel constructs

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S4–S20, Dalal AlDeghaither, Brandon G. Smaglo and Louis M. Weiner

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.407

  7. Modeling of 24-hour glucose and insulin profiles in patients with type 2 diabetes mellitus treated with biphasic insulin aspart

    The Journal of Clinical Pharmacology

    Volume 54, Issue 7, July 2014, Pages: 809–817, Rikke M. Røge, Søren Klim, Niels R. Kristensen, Steen H. Ingwersen and Maria C. Kjellsson

    Version of Record online : 11 MAR 2014, DOI: 10.1002/jcph.270

  8. Enzyme- and transporter-mediated beverage–drug interactions: An update on fruit juices and green tea

    The Journal of Clinical Pharmacology

    Volume 55, Issue 12, December 2015, Pages: 1313–1331, Guohua An, Jatinder Kaur Mukker, Hartmut Derendorf and Reginald F. Frye

    Version of Record online : 30 JUL 2015, DOI: 10.1002/jcph.563

  9. Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling

    The Journal of Clinical Pharmacology

    Volume 56, Issue 3, March 2016, Pages: 266–283, Vijay V. Upreti and Jan L. Wahlstrom

    Version of Record online : 9 OCT 2015, DOI: 10.1002/jcph.585

  10. Contrasting weight changes with LY2605541, a novel long-acting insulin, and insulin glargine despite similar improved glycaemic control in T1DM and T2DM

    Diabetes, Obesity and Metabolism

    Volume 16, Issue 4, April 2014, Pages: 351–356, S. J. Jacober, J. Rosenstock, R. M. Bergenstal, M. J. Prince, Y. Qu and J. M. Beals

    Version of Record online : 31 OCT 2013, DOI: 10.1111/dom.12223

  11. Old and new basal insulin formulations: understanding pharmacodynamics is still relevant in clinical practice

    Diabetes, Obesity and Metabolism

    Volume 16, Issue 8, August 2014, Pages: 695–706, P. Rossetti, F. J. Ampudia-Blasco and J. F. Ascaso

    Version of Record online : 9 FEB 2014, DOI: 10.1111/dom.12256

  12. Stem cell state and the epithelial-to-mesenchymal transition: Implications for cancer therapy

    The Journal of Clinical Pharmacology

    Volume 55, Issue 6, June 2015, Pages: 603–619, Vera S. Donnenberg and Albert D. Donnenberg

    Version of Record online : 7 APR 2015, DOI: 10.1002/jcph.486

  13. Seasonal influenza vaccination and technologies

    The Journal of Clinical Pharmacology

    Volume 54, Issue 7, July 2014, Pages: 719–731, Anne N. Nafziger and David S. Pratt

    Version of Record online : 5 APR 2014, DOI: 10.1002/jcph.299

  14. Clinical pharmacology of bispecific antibody constructs

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S21–S28, Chetan Rathi and Bernd Meibohm

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.445

  15. Recent Advances Using Immunomodulators for Inflammatory Bowel Disease

    The Journal of Clinical Pharmacology

    Volume 53, Issue 6, June 2013, Pages: 575–588, Ole Haagen Nielsen, Jacob Tveiten Bjerrum, Hans Herfarth and Gerhard Rogler

    Version of Record online : 13 FEB 2013, DOI: 10.1002/jcph.2

  16. Challenges and considerations for development of therapeutic proteins in pediatric patients

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S103–S115, Yi Zhang, Xiaohui Wei, Gaurav Bajaj, Jeffrey S. Barrett, Bernd Meibohm, Amita Joshi and Manish Gupta

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.382

  17. Incidence and Costs of Adverse Drug Reactions in a Tertiary Care Pediatric Intensive Care Unit

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 567–573, Wei Du, Victoria Tutag Lehr, Mary Caverly, Lauren Kelm, Jaxk Reeves and Mary Lieh-Lai

    Version of Record online : 28 MAR 2013, DOI: 10.1002/jcph.75

  18. Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development—Opportunities and challenges

    The Journal of Clinical Pharmacology

    Volume 55, Issue S3, March 2015, Pages: S75–S84, Songmao Zheng, Thomas McIntosh and Weirong Wang

    Version of Record online : 23 FEB 2015, DOI: 10.1002/jcph.357

  19. Glucagon-like peptide analogues for type 2 diabetes mellitus

    Intervention Review

    The Cochrane Library

    Deepson S. Shyangdan, Pamela Royle, Christine Clar, Pawana Sharma, Norman Waugh and Ailsa Snaith

    Published Online : 5 OCT 2011, DOI: 10.1002/14651858.CD006423.pub2

  20. Use of Monte Carlo Simulations to Determine Optimal Carbapenem Dosing in Critically Ill Patients Receiving Prolonged Intermittent Renal Replacement Therapy

    The Journal of Clinical Pharmacology

    Susan J. Lewis, Michael B. Kays and Bruce A. Mueller

    Version of Record online : 8 APR 2016, DOI: 10.1002/jcph.727