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There are 18490 results for: content related to: Highlight: BRCA1 and BRCA2 proteins in breast cancer

  1. You have free access to this content
    BRCA1, a ‘complex’ protein involved in the maintenance of genomic stability

    The FEBS Journal

    Volume 282, Issue 4, February 2015, Pages: 630–646, Kienan I. Savage and D. Paul Harkin

    Version of Record online : 2 DEC 2014, DOI: 10.1111/febs.13150

  2. You have full text access to this Open Access content
    Secondary mutations of BRCA1/2 and drug resistance

    Cancer Science

    Volume 102, Issue 4, April 2011, Pages: 663–669, Kiranjit K. Dhillon, Elizabeth M. Swisher and Toshiyasu Taniguchi

    Version of Record online : 30 JAN 2011, DOI: 10.1111/j.1349-7006.2010.01840.x

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    Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study

    Human Mutation

    Volume 31, Issue 3, March 2010, Pages: E1200–E1240, Åke Borg, Robert W. Haile, Kathleen E. Malone, Marinela Capanu, Ahn Diep, Therese Törngren, Sharon Teraoka, Colin B. Begg, Duncan C. Thomas, Patrick Concannon, Lene Mellemkjaer, Leslie Bernstein, Lina Tellhed, Shanyan Xue, Eric R. Olson, Xiaolin Liang, Jessica Dolle, Anne-Lise Børresen-Dale and Jonine L. Bernstein

    Version of Record online : 26 JAN 2010, DOI: 10.1002/humu.21202

  4. You have full text access to this OnlineOpen article
    The BRCA1 ubiquitin ligase and homologous recombination repair

    FEBS Letters

    Volume 585, Issue 18, September 16, 2011, Pages: 2836–2844, Tomohiko Ohta, Ko Sato and Wenwen Wu

    Version of Record online : 9 MAY 2011, DOI: 10.1016/j.febslet.2011.05.005

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    Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation

    International Journal of Cancer

    Volume 77, Issue 4, 12 August 1998, Pages: 600–609, Saijun Fan, Nae-Fang Twu, Ji-An Wang, Ren-qi Yuan, Janet Andres, Itzhak D. Goldberg and Eliot M. Rosen

    Version of Record online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-0215(19980812)77:4<600::AID-IJC21>3.0.CO;2-8

  6. Emerging roles of BRCA1 in transcriptional regulation and DNA repair

    Journal of Cellular Physiology

    Volume 181, Issue 3, December 1999, Pages: 385–392, Yumay Chen, Wen-Hwa Lee and Helen K. Chew

    Version of Record online : 19 OCT 1999, DOI: 10.1002/(SICI)1097-4652(199912)181:3<385::AID-JCP2>3.0.CO;2-4

  7. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

    The Journal of Pathology

    Volume 227, Issue 1, May 2012, Pages: 29–41, Rachael Natrajan, Alan Mackay, Maryou B Lambros, Britta Weigelt, Paul M Wilkerson, Elodie Manie, Anita Grigoriadis, Roger A'Hern, Petra van der Groep, Iwanka Kozarewa, Tatiana Popova, Odette Mariani, Samra Turajlic, Simon J Furney, Richard Marais, Daniel-Nava Rodruigues, Adriana C Flora, Patty Wai, Vidya Pawar, Simon McDade, Jason Carroll, Dominique Stoppa-Lyonnet, Andrew R Green, Ian O Ellis, Charles Swanton, Paul van Diest, Olivier Delattre, Christopher J Lord, William D Foulkes, Anne Vincent-Salomon, Alan Ashworth, Marc Henri Stern and Jorge S Reis-Filho

    Version of Record online : 23 FEB 2012, DOI: 10.1002/path.4003

  8. A guide for functional analysis of BRCA1 variants of uncertain significance

    Human Mutation

    Volume 33, Issue 11, November 2012, Pages: 1526–1537, Gaël A. Millot, Marcelo A. Carvalho, Sandrine M. Caputo, Maaike P.G. Vreeswijk, Melissa A. Brown, Michelle Webb, Etienne Rouleau, Susan L. Neuhausen, Thomas v. O. Hansen, Alvaro Galli, Rita D. Brandão, Marinus J. Blok, Aneliya Velkova, Fergus J. Couch, Alvaro N.A. Monteiro and on behalf of the ENIGMA (Evidence-based Network for the Interpretation of Germline Mutant Alleles) Consortium Functional Assay Working Group

    Version of Record online : 16 JUL 2012, DOI: 10.1002/humu.22150

  9. Insights into the targeted elimination of BRCA1-defective cancer stem cells

    Medicinal Research Reviews

    Volume 32, Issue 5, September 2012, Pages: 948–967, Veena Somasundaram and Priya Srinivas

    Version of Record online : 2 SEP 2010, DOI: 10.1002/med.20229

  10. You have full text access to this Open Access content
    BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein

    Cancer Science

    Volume 102, Issue 10, October 2011, Pages: 1840–1847, Leizhen Wei, Li Lan, Akira Yasui, Kiyoji Tanaka, Masafumi Saijo, Ayako Matsuzawa, Risa Kashiwagi, Emiko Maseki, Yiheng Hu, Jeffrey D. Parvin, Chikashi Ishioka and Natsuko Chiba

    Version of Record online : 17 AUG 2011, DOI: 10.1111/j.1349-7006.2011.02037.x

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    BRCA1 16 years later: risk-associated BRCA1 mutations and their functional implications

    The FEBS Journal

    Volume 277, Issue 15, August 2010, Pages: 3086–3096, Rebecca J. Linger and Patricia A. Kruk

    Version of Record online : 1 JUL 2010, DOI: 10.1111/j.1742-4658.2010.07735.x

  12. Analysis of BRCA1 Variants in Double-Strand Break Repair by Homologous Recombination and Single-Strand Annealing

    Human Mutation

    Volume 34, Issue 3, March 2013, Pages: 439–445, William I. Towler, Jie Zhang, Derek J. R. Ransburgh, Amanda E. Toland, Chikashi Ishioka, Natsuko Chiba and Jeffrey D. Parvin

    Version of Record online : 12 DEC 2012, DOI: 10.1002/humu.22251

  13. Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking


    Volume 27, Issue 9, September 2005, Pages: 884–893, Beric R. Henderson

    Version of Record online : 17 AUG 2005, DOI: 10.1002/bies.20277

  14. Coordinate alterations in the expression of BRCA1, BRCA2, p300, and Rad51 in response to genotoxic and other stresses in human prostate cancer cells

    The Prostate

    Volume 40, Issue 1, 15 June 1999, Pages: 37–49, Renqi Yuan, Saijun Fan, Ji-An Wang, Qinghui Meng, Yongxian Ma, David Schreiber, Itzhak D. Goldberg and Eliot M. Rosen

    Version of Record online : 5 MAY 1999, DOI: 10.1002/(SICI)1097-0045(19990615)40:1<37::AID-PROS5>3.0.CO;2-P

  15. You have full text access to this Open Access content
    Osteopontin can act as an effector for a germline mutation of BRCA1 in malignant transformation of breast cancer-related cells

    Cancer Science

    Volume 101, Issue 6, June 2010, Pages: 1354–1360, Mohamed K. El-Tanani, Hiu-Fung Yuen, Zhanzhong Shi, Angela Platt-Higgins, Niamh E. Buckley, Paul B. Mullan, Denis Paul Harkin, Patrick G. Johnston and Philip S. Rudland

    Version of Record online : 10 MAR 2010, DOI: 10.1111/j.1349-7006.2010.01561.x

  16. Roles of BRCA1 and its interacting proteins


    Volume 22, Issue 8, August 2000, Pages: 728–737, Chu-Xia Deng and Steven G. Brodie

    Version of Record online : 24 JUL 2000, DOI: 10.1002/1521-1878(200008)22:8<728::AID-BIES6>3.0.CO;2-B

  17. Clinico–pathological characteristics of BRCA1- and BRCA2-related breast cancer

    Seminars in Surgical Oncology

    Volume 18, Issue 4, June 2000, Pages: 287–295, Pierre O. Chappuis, Victoria Nethercot and William D. Foulkes

    Version of Record online : 4 MAY 2000, DOI: 10.1002/(SICI)1098-2388(200006)18:4<287::AID-SSU3>3.0.CO;2-5

  18. Skin cancer risk in BRCA1/2 mutation carriers

    British Journal of Dermatology

    Volume 172, Issue 6, June 2015, Pages: 1498–1506, P.V. Gumaste, L.A. Penn, R.M. Cymerman, T. Kirchhoff, D. Polsky and B. McLellan

    Version of Record online : 29 APR 2015, DOI: 10.1111/bjd.13626

  19. Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

    Human Mutation

    Volume 33, Issue 12, December 2012, Pages: 1665–1675, Brooke L. Brewster, Francesca Rossiello, Juliet D. French, Stacey L. Edwards, Ming Wong, Ania Wronski, Phillip Whiley, Nic Waddell, Xiaowei Chen, Betsy Bove, kConFab, John L. Hopper, Esther M. John, Irene Andrulis, Mary Daly, Sara Volorio, Loris Bernard, Bernard Peissel, Siranoush Manoukian, Monica Barile, Sara Pizzamiglio, Paolo Verderio, Amanda B. Spurdle, Paolo Radice, Andrew K. Godwin, Melissa C Southey, Melissa A. Brown and Paolo Peterlongo

    Version of Record online : 2 AUG 2012, DOI: 10.1002/humu.22159

  20. Estrogen upregulation of BRCA1 expression with no effect on localization

    Molecular Carcinogenesis

    Volume 22, Issue 2, June 1998, Pages: 102–109, Donato Romagnolo, Lois A. Annab, Tracy E. Thompson, John I. Risinger, Lori A. Terry, J. Carl Barrett and Cynthia A. Afshari

    Version of Record online : 7 DEC 1998, DOI: 10.1002/(SICI)1098-2744(199806)22:2<102::AID-MC5>3.0.CO;2-O