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There are 24536 results for: content related to: 1 H magnetic resonance spectroscopy of neurodegeneration in a mouse model of niemann-pick type C1 disease

  1. In vivo assessment of neurodegeneration in niemann-pick type C mice by quantitative T2 mapping and diffusion tensor imaging

    Journal of Magnetic Resonance Imaging

    Volume 35, Issue 3, March 2012, Pages: 528–536, John W. Totenhagen, Silvia Lope-Piedrafita, Ivan A. Borbon, Eriko S. Yoshimaru, Robert P. Erickson and Theodore P. Trouard

    Article first published online : 1 NOV 2011, DOI: 10.1002/jmri.22837

  2. Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function

    Clinical and Experimental Pharmacology and Physiology

    Volume 41, Issue 10, October 2014, Pages: 780–787, Adam M Lopez, Sandi J Terpack, Kenneth S Posey, Benny Liu, Charina M Ramirez and Stephen D Turley

    Article first published online : 30 OCT 2014, DOI: 10.1111/1440-1681.12285

  3. Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice

    Journal of Neuroscience Research

    Volume 82, Issue 6, 15 December 2005, Pages: 811–821, Iram Ahmad, Silvia Lope-Piedrafita, Xiaoning Bi, Chad Hicks, Yueqin Yao, Clara Yu, Elizabeth Chaitkin, Christine M. Howison, Lyndon Weberg, Theodore P. Trouard and Robert P. Erickson

    Article first published online : 4 NOV 2005, DOI: 10.1002/jnr.20685

  4. MRI detects therapeutic effects in weanling Niemann-Pick type C mice

    Journal of Neuroscience Research

    Volume 86, Issue 12, September 2008, Pages: 2802–2807, Silvia Lope-Piedrafita, John W. Totenhagen, Chad M. Hicks, Robert P. Erickson and Theodore P. Trouard

    Article first published online : 30 MAY 2008, DOI: 10.1002/jnr.21707

  5. Niemann–Pick disease type C

    Clinical Genetics

    Volume 64, Issue 4, October 2003, Pages: 269–281, MT Vanier and G Millat

    Article first published online : 15 SEP 2003, DOI: 10.1034/j.1399-0004.2003.00147.x

  6. Astrocyte-only Npc1 reduces neuronal cholesterol and triples life span of Npc1–/– mice

    Journal of Neuroscience Research

    Volume 86, Issue 13, October 2008, Pages: 2848–2856, Min Zhang, Diana Strnatka, Carolyn Donohue, Janice L. Hallows, Inez Vincent and Robert P. Erickson

    Article first published online : 23 MAY 2008, DOI: 10.1002/jnr.21730

  7. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains

    Glia

    Volume 58, Issue 11, 15 August 2010, Pages: 1267–1281, A. Kodam, M. Maulik, K. Peake, A. Amritraj, K. S. Vetrivel, G. Thinakaran, J. E. Vance and S. Kar

    Article first published online : 21 APR 2010, DOI: 10.1002/glia.21001

  8. You have full text access to this OnlineOpen article
    Immune dysfunction in Niemann-Pick disease type C

    Journal of Neurochemistry

    Nick Platt, Annelise O. Speak, Alexandria Colaco, James Gray, David A. Smith, Ian M. Williams, Kerri-Lee Wallom and Frances M. Platt

    Article first published online : 4 JUN 2015, DOI: 10.1111/jnc.13138

  9. Molecular analysis of 30 Niemann–Pick type C patients from Spain

    Clinical Genetics

    Volume 80, Issue 1, July 2011, Pages: 39–49, J Macías-Vidal, L Rodríguez-Pascau, G Sánchez-Ollé, M Lluch, L Vilageliu, D Grinberg, MJ Coll and the Spanish NPC Working Group

    Article first published online : 6 JUL 2010, DOI: 10.1111/j.1399-0004.2010.01504.x

  10. Identification of 58 novel mutations in Niemann-Pick disease type C: Correlation with biochemical phenotype and importance of PTC1-like domains in NPC1

    Human Mutation

    Volume 22, Issue 4, October 2003, Pages: 313–325, Walter D. Park, John F. O'Brien, Patrick A. Lundquist, Daniel L. Kraft, Cate Walsh Vockley, Pamela S. Karnes, Marc C. Patterson and Karen Snow

    Article first published online : 26 AUG 2003, DOI: 10.1002/humu.10255

  11. You have free access to this content
    Decreased Npc1 Gene Dosage in Mice Is Associated With Weight Gain

    Obesity

    Volume 18, Issue 7, July 2010, Pages: 1457–1459, David Jelinek, Randall A. Heidenreich, Robert P. Erickson and William S. Garver

    Article first published online : 6 SEP 2012, DOI: 10.1038/oby.2009.415

  12. You have free access to this content
    The Cytosolic Adaptor AP-1A Is Essential for the Trafficking and Function of Niemann-Pick Type C Proteins

    Traffic

    Volume 14, Issue 4, April 2013, Pages: 458–469, Steve Poirier, Gaétan Mayer, Stephanie R. Murphy, William S. Garver, Ta Yuan Chang, Peter Schu and Nabil G. Seidah

    Article first published online : 20 FEB 2013, DOI: 10.1111/tra.12046

  13. Amelioration of enteric neuropathology in a mouse model of Niemann-Pick C by Npc1 expression in enteric glia

    Journal of Neuroscience Research

    Volume 87, Issue 13, October 2009, Pages: 2994–3001, Raj Kapur, Carolyn Donohue, David Jelinek and Robert P. Erickson

    Article first published online : 26 MAY 2009, DOI: 10.1002/jnr.22126

  14. Sperm defects in mice lacking a functional Niemann–Pick C1 protein

    Molecular Reproduction and Development

    Volume 73, Issue 10, October 2006, Pages: 1284–1291, Jun Fan, Hiroto Akabane, Stephanie N. Graham, Laura L. Richardson and Guo-Zhang Zhu

    Article first published online : 18 JUL 2006, DOI: 10.1002/mrd.20559

  15. Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice

    Liver International

    Volume 30, Issue 6, July 2010, Pages: 887–897, María Gabriela Morales, Ludwig Amigo, Elisa Balboa, Mariana Acuña, Juan Castro, Héctor Molina, Juan Francisco Miquel, Flavio Nervi, Attilio Rigotti and Silvana Zanlungo

    Article first published online : 8 APR 2010, DOI: 10.1111/j.1478-3231.2010.02230.x

  16. The proteasome inhibitor bortezomib reduced cholesterol accumulation in fibroblasts from Niemann–Pick type C patients carrying missense mutations

    FEBS Journal

    Volume 281, Issue 19, October 2014, Pages: 4450–4466, Judit Macías-Vidal, Marisa Girós, Martina Guerrero, Pere Gascón, Joan Serratosa, Oriol Bachs and Maria Josep Coll

    Article first published online : 21 AUG 2014, DOI: 10.1111/febs.12954

  17. You have free access to this content
    NPC1 Gene Deficiency Leads to Lack of Neural Stem Cell Self-Renewal and Abnormal Differentiation Through Activation of p38 Mitogen-Activated Protein Kinase Signaling

    STEM CELLS

    Volume 24, Issue 2, February 2006, Pages: 292–298, Se-Ran Yang, Sun-Jung Kim, Kyoung-Hee Byun, Brian Hutchinson, Bong-Hee Lee, Makoto Michikawa, Yong-Soon Lee and Kyung-Sun Kang

    Article first published online : 11 AUG 2005, DOI: 10.1634/stemcells.2005-0221

  18. Magnetization transfer contrast imaging in Niemann pick type C mouse liver

    Journal of Magnetic Resonance Imaging

    Volume 18, Issue 3, September 2003, Pages: 321–327, Jingyu Guo, Robert Erickson, Theodore Trouard, Jean-Philippe Galons and Robert Gillies

    Article first published online : 18 AUG 2003, DOI: 10.1002/jmri.10404

  19. Characterization of liver disease and lipid metabolism in the Niemann-Pick C1 mouse

    Journal of Cellular Biochemistry

    Volume 101, Issue 2, 15 May 2007, Pages: 498–516, William S. Garver, David Jelinek, Janice N. Oyarzo, James Flynn, Matthew Zuckerman, Kumar Krishnan, Byung H. Chung and Randall A. Heidenreich

    Article first published online : 10 JAN 2007, DOI: 10.1002/jcb.21200

  20. HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells

    STEM CELLS

    Volume 33, Issue 4, April 2015, Pages: 1075–1088, Minami Soga, Yoichi Ishitsuka, Makoto Hamasaki, Kaori Yoneda, Hirokazu Furuya, Muneaki Matsuo, Hironobu Ihn, Noemi Fusaki, Kimitoshi Nakamura, Naomi Nakagata, Fumio Endo, Tetsumi Irie and Takumi Era

    Article first published online : 24 MAR 2015, DOI: 10.1002/stem.1917

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    Corrigendum: Corrigendum: HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells

    Vol. 33, Issue 9, 2885–2886, Article first published online: 24 AUG 2015