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There are 10871 results for: content related to: Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

  1. DHA diet reduces AD pathology in young APPswe/PS1ΔE9 transgenic mice: Possible gender effects

    Journal of Neuroscience Research

    Volume 88, Issue 5, April 2010, Pages: 1026–1040, Sylvia E. Perez, Brian M. Berg, Kenneth A. Moore, Bin He, Scott E. Counts, Jason J. Fritz, Yuan-Shih Hu, Orly Lazarov, James J. Lah and Elliott J. Mufson

    Article first published online : 26 OCT 2009, DOI: 10.1002/jnr.22266

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    Author Index

    Nephrology

    Volume 19, Issue S2, May 2014, Pages: 203–217,

    Article first published online : 24 APR 2014, DOI: 10.1111/nep.12238

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    Processing of Wild-Type and Mutant Familial Alzheimer’s Disease-Associated Presenilin-1 in Cultured Neurons

    Journal of Neurochemistry

    Volume 73, Issue 1, July 1999, Pages: 31–40, Conrad C. Weihl, Ghanaysham D. Ghadge, Richard J. Miller and Raymond P. Roos

    Article first published online : 5 MAY 2004, DOI: 10.1046/j.1471-4159.1999.0730031.x

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    Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ-secretase activity

    Journal of Neurochemistry

    Volume 94, Issue 5, September 2005, Pages: 1315–1328, A. L. Brunkan, M. Martinez, J. Wang, E. S. Walker, D. Beher, M. S. Shearman and A. M. Goate

    Article first published online : 7 JUL 2005, DOI: 10.1111/j.1471-4159.2005.03278.x

  5. Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice

    Journal of Comparative Neurology

    Volume 521, Issue 6, 15 April 2013, Pages: 1395–1408, Brian A. Couch, Meghan E. Kerrisk, Adam C. Kaufman, Haakon B. Nygaard, Stephen M. Strittmatter and Anthony J. Koleske

    Article first published online : 20 FEB 2013, DOI: 10.1002/cne.23239

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    Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling

    Journal of Neurochemistry

    Volume 121, Issue 6, June 2012, Pages: 964–973, Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Haruhiko Akiyama, Ryosuke Takahashi, Takeshi Kihara, Shun Shimohama and Ayae Kinoshita

    Article first published online : 23 APR 2012, DOI: 10.1111/j.1471-4159.2012.07741.x

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    PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations

    The EMBO Journal

    Volume 23, Issue 13, July 7, 2004, Pages: 2586–2596, Lia Baki, Junichi Shioi, Paul Wen, Zhiping Shao, Alexander Schwarzman, Miguel Gama-Sosa, Rachael Neve and Nikolaos K Robakis

    Article first published online : 10 JUN 2004, DOI: 10.1038/sj.emboj.7600251

  8. Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production

    Journal of Neurochemistry

    Volume 133, Issue 3, May 2015, Pages: 409–421, Alexandre Matz, Blanka Halamoda-Kenzaoui, Romain Hamelin, Sebastien Mosser, Jean-René Alattia, Mitko Dimitrov, Marc Moniatte and Patrick C. Fraering

    Article first published online : 24 FEB 2015, DOI: 10.1111/jnc.12996

  9. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

    Annals of Neurology

    Volume 55, Issue 6, June 2004, Pages: 801–814, Fabrizio Trinchese, Shumin Liu, Fortunato Battaglia, Sean Walter, Paul M. Mathews and Ottavio Arancio

    Article first published online : 27 MAY 2004, DOI: 10.1002/ana.20101

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    Reconstitution of γ-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of γ-secretase complex

    Genes to Cells

    Volume 11, Issue 1, January 2006, Pages: 83–93, Hirohisa Shiraishi, Toshihiro Marutani, Hua-Qin Wang, Yasuhiro Maeda, Yukihisa Kurono, Akihiko Takashima, Wataru Araki, Masaki Nishimura, Katsuhiko Yanagisawa and Hiroto Komano

    Article first published online : 22 NOV 2005, DOI: 10.1111/j.1365-2443.2005.00914.x

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    Caspase cleaved presenilin-1 is part of active γ-secretase complexes

    Journal of Neurochemistry

    Volume 97, Issue 2, April 2006, Pages: 356–364, Camilla A. Hansson, Bogdan O. Popescu, Hanna Laudon, Angel Cedazo-Minguez, Laurentiu M. Popescu, Bengt Winblad and Maria Ankarcrona

    Article first published online : 15 MAR 2006, DOI: 10.1111/j.1471-4159.2006.03735.x

  12. Inhibition of c-Jun N-terminal kinase activation reverses Alzheimer disease phenotypes in APPswe/PS1dE9 mice

    Annals of Neurology

    Volume 77, Issue 4, April 2015, Pages: 637–654, Qiong Zhou, Man Wang, Ying Du, Wei Zhang, Miao Bai, Zhuo Zhang, Zhuyi Li and Jianting Miao

    Article first published online : 2 MAR 2015, DOI: 10.1002/ana.24361

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    The regulation of presenilin-1 by nerve growth factor

    Journal of Neurochemistry

    Volume 76, Issue 3, February 2001, Pages: 679–689, Scott E. Counts, James J. Lah and Allan I. Levey

    Article first published online : 7 JUL 2008, DOI: 10.1046/j.1471-4159.2001.00014.x

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    Alzheimer's Disease-Associated Ubiquilin-1 Regulates Presenilin-1 Accumulation and Aggresome Formation

    Traffic

    Volume 12, Issue 3, March 2011, Pages: 330–348, Jayashree Viswanathan, Annakaisa Haapasalo, Claudia Böttcher, Riitta Miettinen, Kaisa M. A. Kurkinen, Alice Lu, Anne Thomas, Christa J. Maynard, Donna Romano, Bradley T. Hyman, Oksana Berezovska, Lars Bertram, Hilkka Soininen, Nico P. Dantuma, Rudolph E. Tanzi and Mikko Hiltunen

    Article first published online : 7 JAN 2011, DOI: 10.1111/j.1600-0854.2010.01149.x

  15. Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction

    The EMBO Journal

    Volume 34, Issue 22, 12 November 2015, Pages: 2820–2839, Tziona Ben-Gedalya, Lorna Moll, Michal Bejerano-Sagie, Samuel Frere, Wayne A Cabral, Dinorah Friedmann-Morvinski, Inna Slutsky, Tal Burstyn-Cohen, Joan C Marini and Ehud Cohen

    Article first published online : 5 OCT 2015, DOI: 10.15252/embj.201592042

  16. Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

    Brain Pathology

    Volume 22, Issue 5, September 2012, Pages: 636–653, Ester Aso, Selene Lomoio, Irene López-González, Laura Joda, Margarita Carmona, Núria Fernández-Yagüe, Jesús Moreno, Salvador Juvés, Aurora Pujol, Reinald Pamplona, Manuel Portero-Otin, Virginia Martín, Mario Díaz and Isidro Ferrer

    Article first published online : 13 JAN 2012, DOI: 10.1111/j.1750-3639.2011.00560.x

  17. Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

    Journal of Neuroscience Research

    Volume 66, Issue 1, 1 October 2001, Pages: 122–134, Bogdan O. Popescu, Angel Cedazo-Minguez, Laurentiu M. Popescu, Bengt Winblad, Richard F. Cowburn and Maria Ankarcrona

    Article first published online : 26 SEP 2001, DOI: 10.1002/jnr.1204

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    Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer’s disease

    Journal of Neurochemistry

    Volume 115, Issue 3, November 2010, Pages: 574–584, Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim, Kwonseop Kim, Woo-Joo Song and Sul-Hee Chung

    Article first published online : 19 AUG 2010, DOI: 10.1111/j.1471-4159.2010.06769.x

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    Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer’s disease

    Genes, Brain and Behavior

    Volume 8, Issue 2, March 2009, Pages: 143–148, M. Filali, R. Lalonde and S. Rivest

    Article first published online : 11 DEC 2008, DOI: 10.1111/j.1601-183X.2008.00453.x

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    N-cadherin-based adhesion enhances Aβ release and decreases Aβ42/40 ratio

    Journal of Neurochemistry

    Volume 108, Issue 2, January 2009, Pages: 350–360, Kengo Uemura, Christina M. Lill, Mary Banks, Megumi Asada, Nobuhisa Aoyagi, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Takaaki Nishimoto, Hachiro Sugimoto, Ryosuke Takahashi, Bradley T. Hyman, Shun Shimohama, Oksana Berezovska and Ayae Kinoshita

    Article first published online : 1 NOV 2008, DOI: 10.1111/j.1471-4159.2008.05760.x