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There are 4645 results for: content related to: Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

  1. DHA diet reduces AD pathology in young APPswe/PS1ΔE9 transgenic mice: Possible gender effects

    Journal of Neuroscience Research

    Volume 88, Issue 5, April 2010, Pages: 1026–1040, Sylvia E. Perez, Brian M. Berg, Kenneth A. Moore, Bin He, Scott E. Counts, Jason J. Fritz, Yuan-Shih Hu, Orly Lazarov, James J. Lah and Elliott J. Mufson

    Article first published online : 26 OCT 2009, DOI: 10.1002/jnr.22266

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    Author Index

    Nephrology

    Volume 19, Issue S2, May 2014, Pages: 203–217,

    Article first published online : 24 APR 2014, DOI: 10.1111/nep.12238

  3. Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis

    Hippocampus

    Karienn S. Montgomery, George Edwards III, Yona Levites, Ashok Kumar, Catherine E. Myers, Mark A. Gluck, Barry Setlow and Jennifer L. Bizon

    Article first published online : 19 OCT 2015, DOI: 10.1002/hipo.22535

  4. Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production

    Journal of Neurochemistry

    Volume 133, Issue 3, May 2015, Pages: 409–421, Alexandre Matz, Blanka Halamoda-Kenzaoui, Romain Hamelin, Sebastien Mosser, Jean-René Alattia, Mitko Dimitrov, Marc Moniatte and Patrick C. Fraering

    Article first published online : 24 FEB 2015, DOI: 10.1111/jnc.12996

  5. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

    Annals of Neurology

    Volume 55, Issue 6, June 2004, Pages: 801–814, Fabrizio Trinchese, Shumin Liu, Fortunato Battaglia, Sean Walter, Paul M. Mathews and Ottavio Arancio

    Article first published online : 27 MAY 2004, DOI: 10.1002/ana.20101

  6. Inhibition of c-Jun N-terminal kinase activation reverses Alzheimer disease phenotypes in APPswe/PS1dE9 mice

    Annals of Neurology

    Volume 77, Issue 4, April 2015, Pages: 637–654, Qiong Zhou, Man Wang, Ying Du, Wei Zhang, Miao Bai, Zhuo Zhang, Zhuyi Li and Jianting Miao

    Article first published online : 2 MAR 2015, DOI: 10.1002/ana.24361

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    Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ-secretase activity

    Journal of Neurochemistry

    Volume 94, Issue 5, September 2005, Pages: 1315–1328, A. L. Brunkan, M. Martinez, J. Wang, E. S. Walker, D. Beher, M. S. Shearman and A. M. Goate

    Article first published online : 7 JUL 2005, DOI: 10.1111/j.1471-4159.2005.03278.x

  8. Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice

    Journal of Comparative Neurology

    Volume 521, Issue 6, 15 April 2013, Pages: 1395–1408, Brian A. Couch, Meghan E. Kerrisk, Adam C. Kaufman, Haakon B. Nygaard, Stephen M. Strittmatter and Anthony J. Koleske

    Article first published online : 20 FEB 2013, DOI: 10.1002/cne.23239

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    Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer’s disease

    Genes, Brain and Behavior

    Volume 8, Issue 2, March 2009, Pages: 143–148, M. Filali, R. Lalonde and S. Rivest

    Article first published online : 11 DEC 2008, DOI: 10.1111/j.1601-183X.2008.00453.x

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    N-cadherin-based adhesion enhances Aβ release and decreases Aβ42/40 ratio

    Journal of Neurochemistry

    Volume 108, Issue 2, January 2009, Pages: 350–360, Kengo Uemura, Christina M. Lill, Mary Banks, Megumi Asada, Nobuhisa Aoyagi, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Takaaki Nishimoto, Hachiro Sugimoto, Ryosuke Takahashi, Bradley T. Hyman, Shun Shimohama, Oksana Berezovska and Ayae Kinoshita

    Article first published online : 1 NOV 2008, DOI: 10.1111/j.1471-4159.2008.05760.x

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    Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling

    Journal of Neurochemistry

    Volume 121, Issue 6, June 2012, Pages: 964–973, Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Haruhiko Akiyama, Ryosuke Takahashi, Takeshi Kihara, Shun Shimohama and Ayae Kinoshita

    Article first published online : 23 APR 2012, DOI: 10.1111/j.1471-4159.2012.07741.x

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    Processing of Wild-Type and Mutant Familial Alzheimer’s Disease-Associated Presenilin-1 in Cultured Neurons

    Journal of Neurochemistry

    Volume 73, Issue 1, July 1999, Pages: 31–40, Conrad C. Weihl, Ghanaysham D. Ghadge, Richard J. Miller and Raymond P. Roos

    Article first published online : 5 MAY 2004, DOI: 10.1046/j.1471-4159.1999.0730031.x

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    Reconstitution of γ-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of γ-secretase complex

    Genes to Cells

    Volume 11, Issue 1, January 2006, Pages: 83–93, Hirohisa Shiraishi, Toshihiro Marutani, Hua-Qin Wang, Yasuhiro Maeda, Yukihisa Kurono, Akihiko Takashima, Wataru Araki, Masaki Nishimura, Katsuhiko Yanagisawa and Hiroto Komano

    Article first published online : 22 NOV 2005, DOI: 10.1111/j.1365-2443.2005.00914.x

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    Hypoxia-Triggered m-Calpain Activation Evokes Endoplasmic Reticulum Stress and Neuropathogenesis in a Transgenic Mouse Model of Alzheimer's Disease

    CNS Neuroscience & Therapeutics

    Volume 19, Issue 10, October 2013, Pages: 820–833, Chun-Yan Wang, Jing-Wei Xie, Tao Wang, Ye Xu, Jian-Hui Cai, Xu Wang, Bao-Lu Zhao, Li An and Zhan-You Wang

    Article first published online : 27 JUL 2013, DOI: 10.1111/cns.12151

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    Caspase cleaved presenilin-1 is part of active γ-secretase complexes

    Journal of Neurochemistry

    Volume 97, Issue 2, April 2006, Pages: 356–364, Camilla A. Hansson, Bogdan O. Popescu, Hanna Laudon, Angel Cedazo-Minguez, Laurentiu M. Popescu, Bengt Winblad and Maria Ankarcrona

    Article first published online : 15 MAR 2006, DOI: 10.1111/j.1471-4159.2006.03735.x

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    The regulation of presenilin-1 by nerve growth factor

    Journal of Neurochemistry

    Volume 76, Issue 3, February 2001, Pages: 679–689, Scott E. Counts, James J. Lah and Allan I. Levey

    Article first published online : 7 JUL 2008, DOI: 10.1046/j.1471-4159.2001.00014.x

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    Alzheimer's Disease-Associated Ubiquilin-1 Regulates Presenilin-1 Accumulation and Aggresome Formation

    Traffic

    Volume 12, Issue 3, March 2011, Pages: 330–348, Jayashree Viswanathan, Annakaisa Haapasalo, Claudia Böttcher, Riitta Miettinen, Kaisa M. A. Kurkinen, Alice Lu, Anne Thomas, Christa J. Maynard, Donna Romano, Bradley T. Hyman, Oksana Berezovska, Lars Bertram, Hilkka Soininen, Nico P. Dantuma, Rudolph E. Tanzi and Mikko Hiltunen

    Article first published online : 7 JAN 2011, DOI: 10.1111/j.1600-0854.2010.01149.x

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    Presenilin function and γ-secretase activity

    Journal of Neurochemistry

    Volume 93, Issue 4, May 2005, Pages: 769–792, A. L. Brunkan and A. M. Goate

    Article first published online : 1 APR 2005, DOI: 10.1111/j.1471-4159.2005.03099.x

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    Impairments of long-term depression induction and motor coordination precede Aβ accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice

    Journal of Neurochemistry

    Volume 130, Issue 3, August 2014, Pages: 432–443, Yuki Kuwabara, Masato Ishizeki, Naoto Watamura, Junya Toba, Aya Yoshii, Takafumi Inoue and Toshio Ohshima

    Article first published online : 19 APR 2014, DOI: 10.1111/jnc.12728

  20. Reduction of hippocampal N-acetyl aspartate level in aged APPSwe/PS1dE9 transgenic mice is associated with degeneration of CA3 pyramidal neurons

    Journal of Neuroscience Research

    Volume 88, Issue 14, 1 November 2010, Pages: 3155–3160, Wei Xu, Yanqiang Zhan, Wei Huang, Xuxia Wang, Sumin Zhang and Hao Lei

    Article first published online : 30 AUG 2010, DOI: 10.1002/jnr.22479