Search Results

There are 18037 results for: content related to: Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

  1. Consideration of the linear concentration increase of the unbound drug fraction in plasma

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 2, February 2009, Pages: 383–393, Leonid M. Berezhkovskiy

    Version of Record online : 14 AUG 2008, DOI: 10.1002/jps.21470

  2. Modeling microstructure development and release kinetics in controlled drug release coatings

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 1, January 2009, Pages: 169–186, David M. Saylor, Chang-Soo Kim, Dinesh V. Patwardhan and James A. Warren

    Version of Record online : 14 MAY 2008, DOI: 10.1002/jps.21416

  3. Two-scale, three-phase theory for swelling drug delivery systems. Part I: Constitutive theory

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 5, May 2008, Pages: 1878–1903, T.F. Weinstein, L.S. Bennethum and J.H. Cushman

    Version of Record online : 6 DEC 2007, DOI: 10.1002/jps.21208

  4. You have free access to this content
    Synthesis, pharmacology, crystal properties, and quantitative solvation studies from a drug transport perspective for three new 1,2,4-thiadiazoles

    Journal of Pharmaceutical Sciences

    Volume 99, Issue 9, September 2010, Pages: 3754–3768, German L. Perlovich, Tatyana V. Volkova, Alexey N. Proshin, Dmitriy Yu Sergeev, Cong Trinh Bui, Ludmila N. Petrova and Sergey O. Bachurin

    Version of Record online : 12 APR 2010, DOI: 10.1002/jps.22143

  5. Extent and mechanism of solvation and partitioning of isomers of substituted benzoic acids: A thermodynamic study in the solid state and in solution

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 9, September 2008, Pages: 3883–3896, German L. Perlovich, Tatyana V. Volkova, Alex N. Manin and Annette Bauer-Brandl

    Version of Record online : 15 JAN 2008, DOI: 10.1002/jps.21260

  6. A multiphase microscopic diffusion model for stratum corneum permeability. II. estimation of physicochemical parameters, and application to a large permeability database

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 11, November 2007, Pages: 3024–3051, Tsuo-Feng Wang, Gerald B. Kasting and Johannes M. Nitsche

    Version of Record online : 17 SEP 2007, DOI: 10.1002/jps.20883

  7. You have free access to this content
    Liposomal delivery of hydrophobic weak acids: Enhancement of drug retention using a high intraliposomal pH

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 1, January 2008, Pages: 433–454, Vijay Joguparthi and Bradley D. Anderson

    Version of Record online : 5 OCT 2007, DOI: 10.1002/jps.21135

  8. Dynamic heat capacity and relaxation time of ultraviscous melt and glassy acetaminophen

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 5, May 2006, Pages: 1006–1021, E. Tombari, S. Presto, G.P. Johari and Ravi M. Shanker

    Version of Record online : 21 MAR 2006, DOI: 10.1002/jps.20601

  9. On the calculation of the concentration dependence of drug binding to plasma proteins with multiple binding sites of different affinities: Determination of the possible variation of the unbound drug fraction and calculation of the number of binding sites of the protein

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 2, February 2007, Pages: 249–257, Leonid M. Berezhkovskiy

    Version of Record online : 18 OCT 2006, DOI: 10.1002/jps.20777

  10. You have free access to this content
    Polymorphism of alprazolam (Xanax®): A review of its crystalline phases and identification, crystallographic characterization, and crystal structure of a new polymorph (form III)

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 5, May 2007, Pages: 1114–1130, Héctor Novoa de Armas, Oswald M. Peeters, Guy Van den Mooter and Norbert Blaton

    Version of Record online : 23 APR 2007, DOI: 10.1002/jps.20930

  11. The influence of drug kinetics in blood on the calculation of oral bioavailability in linear pharmacokinetics: The traditional equation may considerably overestimate the true value

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 4, April 2006, Pages: 834–848, Leonid M. Berezhkovskiy

    Version of Record online : 21 FEB 2006, DOI: 10.1002/jps.20570

  12. A multiphase microscopic diffusion model for stratum corneum permeability. I. formulation, solution, and illustrative results for representative compounds

    Journal of Pharmaceutical Sciences

    Volume 95, Issue 3, March 2006, Pages: 620–648, Tsuo-Feng Wang, Gerald B. Kasting and Johannes M. Nitsche

    Version of Record online : 30 JAN 2006, DOI: 10.1002/jps.20509

  13. You have free access to this content
    PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically-based pharmacokinetic modeling approach

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 10, October 2011, Pages: 4127–4157, Patrick Poulin, Rhys D. O. Jones, Hannah M. Jones, Christopher R. Gibson, Malcolm Rowland, Jenny Y. Chien, Barbara J. Ring, Kimberly K. Adkison, M. Sherry Ku, Handan He, Ragini Vuppugalla, Punit Marathe, Volker Fischer, Sandeep Dutta, Vikash K. Sinha, Thorir Björnsson, Thierry Lavé and James W. T. Yates

    Version of Record online : 3 MAY 2011, DOI: 10.1002/jps.22550

  14. You have free access to this content
    Analysis of known crystals to design polymorph prediction strategies

    Journal of Pharmaceutical Sciences

    Volume 96, Issue 5, May 2007, Pages: 1203–1236, P.H. Young and H.Y. Ando

    Version of Record online : 23 APR 2007, DOI: 10.1002/jps.20922

  15. Comparative effects of pH and ionic strength on protein–protein interactions, unfolding, and aggregation for IgG1 antibodies

    Journal of Pharmaceutical Sciences

    Volume 99, Issue 12, December 2010, Pages: 4830–4848, Erinc Sahin, Adeola O. Grillo, Melissa D. Perkins and Christopher J. Roberts

    Version of Record online : 19 MAY 2010, DOI: 10.1002/jps.22198

  16. The influence of hepatic transport on the distribution volumes and mean residence time of drug in the body and the accuracy of estimating these parameters by the traditional pharmacokinetic calculations

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 11, November 2011, Pages: 5031–5047, Leonid M. Berezhkovskiy

    Version of Record online : 15 JUL 2011, DOI: 10.1002/jps.22696

  17. Factors affecting calcium precipitation during neutralisation in a simulated intestinal environment

    Journal of Pharmaceutical Sciences

    Volume 99, Issue 10, October 2010, Pages: 4183–4191, Sandra Goss, Jennifer Prushko and Robin Bogner

    Version of Record online : 29 MAR 2010, DOI: 10.1002/jps.22131

  18. Dielectric properties of pharmaceutical materials relevant to microwave processing: Effects of field frequency, material density, and moisture content

    Journal of Pharmaceutical Sciences

    Volume 99, Issue 2, February 2010, Pages: 941–957, Paul W.S. Heng, Z.H. Loh, Celine V. Liew and C.C. Lee

    Version of Record online : 25 AUG 2009, DOI: 10.1002/jps.21872

  19. You have free access to this content
    Molecular complexes of alprazolam with carboxylic acids, boric acid, boronic acids, and phenols. Evaluation of supramolecular heterosynthons mediated by a triazole ring

    Journal of Pharmaceutical Sciences

    Volume 99, Issue 9, September 2010, Pages: 3743–3753, Sunil Varughese, Yasser Azim and Gautam R. Desiraju

    Version of Record online : 5 APR 2010, DOI: 10.1002/jps.22117

  20. Thermodynamic and structural aspects of sulfonamide crystals and solutions

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 12, December 2009, Pages: 4738–4755, German L. Perlovich, Valery V. Tkachev, Nadezda N. Strakhova, Vladimir P. Kazachenko, Tatyana V. Volkova, Oleg V. Surov, Klaus-Jürgen Schaper and Oleg A. Raevsky

    Version of Record online : 30 APR 2009, DOI: 10.1002/jps.21784