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There are 39441 results for: content related to: Developability index: A rapid in silico tool for the screening of antibody aggregation propensity

  1. You have free access to this content
    Hydrogen–Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 2, February 2015, Pages: 327–345, Ranajoy Majumdar, C. Russell Middaugh, David D. Weis and David B. Volkin

    Version of Record online : 29 OCT 2014, DOI: 10.1002/jps.24224

  2. High shear rheology and anisotropy in concentrated solutions of monoclonal antibodies

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 8, August 2013, Pages: 2538–2549, Isidro E. Zarraga, Rosalynn Taing, Jonathan Zarzar, Jacob Luoma, Jenny Hsiung, Ankit Patel and Fredric J. Lim

    Version of Record online : 19 JUL 2013, DOI: 10.1002/jps.23647

  3. Characterization of the co-elution of host cell proteins with monoclonal antibodies during protein A purification

    Biotechnology Progress

    Qingchun Zhang, Andrew M. Goetze, Huanchun Cui, Jenna Wylie, Ben Tillotson, Art Hewig, Michael P. Hall and Gregory C. Flynn

    Version of Record online : 6 MAY 2016, DOI: 10.1002/btpr.2272

  4. Stability of Monoclonal Antibodies at High-Concentration: Head-to-Head Comparison of the IgG1 and IgG4 Subclass

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 1, January 2014, Pages: 115–127, Martin S. Neergaard, Anders D. Nielsen, Henrik Parshad and Marco Van De Weert

    Version of Record online : 26 NOV 2013, DOI: 10.1002/jps.23788

  5. Assessment of net charge and protein–protein interactions of different monoclonal antibodies

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 7, July 2011, Pages: 2551–2562, Christian Lehermayr, Hanns-Christian Mahler, Karsten Mäder and Stefan Fischer

    Version of Record online : 3 FEB 2011, DOI: 10.1002/jps.22506

  6. Evaluation of a non-arrhenius model for therapeutic monoclonal antibody aggregation

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 7, July 2011, Pages: 2526–2542, Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer and Bernhardt L. Trout

    Version of Record online : 25 JAN 2011, DOI: 10.1002/jps.22493

  7. You have full text access to this OnlineOpen article
    A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies

    Biotechnology Progress

    Volume 30, Issue 5, September/October 2014, Pages: 1114–1124, Nabila Aboulaich, Wai Keen Chung, Jenny Heidbrink Thompson, Christopher Larkin, David Robbins and Min Zhu

    Version of Record online : 26 JUL 2014, DOI: 10.1002/btpr.1948

  8. The Radiopharmaceutical Science of Monoclonal Antibodies and Peptides for Imaging and Targeted In Situ Radiotherapy of Malignancies

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Raymond M. Reilly

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse318

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    Detection of receptor clustering by flow cytometric fluorescence anisotropy measurements

    Cytometry

    Volume 40, Issue 4, 1 August 2000, Pages: 292–306, László Bene, Mack J. Fulwyler and Sándor Damjanovich

    Version of Record online : 24 JUL 2000, DOI: 10.1002/1097-0320(20000801)40:4<292::AID-CYTO5>3.0.CO;2-#

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    Optimized Nonclinical Safety Assessment Strategies Supporting Clinical Development of Therapeutic Monoclonal Antibodies Targeting Inflammatory Diseases

    Drug Development Research

    Volume 75, Issue 3, May 2014, Pages: 115–161, Frank R. Brennan, Annick Cauvin, Jay Tibbitts and Alison Wolfreys

    Version of Record online : 29 APR 2014, DOI: 10.1002/ddr.21173

  11. Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 12, December 2013, Pages: 4315–4329, Roxana E. Iacob, George M. Bou-Assaf, Lee Makowski, John R. Engen, Steven A. Berkowitz and Damian Houde

    Version of Record online : 17 OCT 2013, DOI: 10.1002/jps.23754

  12. Eliminating tyrosine sequence variants in CHO cell lines producing recombinant monoclonal antibodies

    Biotechnology and Bioengineering

    Volume 110, Issue 4, April 2013, Pages: 1087–1097, Lauren Feeney, Veronica Carvalhal, X. Christopher Yu, Betty Chan, David A. Michels, Yajun Jennifer Wang, Amy Shen, Jan Ressl, Brendon Dusel and Michael W. Laird

    Version of Record online : 15 FEB 2013, DOI: 10.1002/bit.24759

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    Chimeric, divalent and tetravalent anti-CD19 monoclonal antibodies with potent in vitro and in vivo antitumor activity against human B-cell lymphoma and pre-B acute lymphoblastic leukemia cell lines

    International Journal of Cancer

    Volume 129, Issue 2, 15 July 2011, Pages: 497–506, Xiao-Yun Liu, Laurentiu M. Pop, Lydia Tsai, Iliodora V. Pop and Ellen S. Vitetta

    Version of Record online : 16 NOV 2010, DOI: 10.1002/ijc.25695

  14. Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13

    Journal of Thrombosis and Haemostasis

    Volume 13, Issue 11, November 2015, Pages: 2063–2075, L. Deforche, E. Roose, A. Vandenbulcke, N. Vandeputte, H. B. Feys, T. A. Springer, L. Z. Mi, J. Muia, J. E. Sadler, K. Soejima, H. Rottensteiner, H. Deckmyn, S. F. De Meyer and K. Vanhoorelbeke

    Version of Record online : 20 OCT 2015, DOI: 10.1111/jth.13149

  15. Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 6, June 2015, Pages: 1866–1884, Liming Liu

    Version of Record online : 14 APR 2015, DOI: 10.1002/jps.24444

  16. A screening tool for therapeutic monoclonal antibodies: Identifying the most stable protein and its best formulation based on thioflavin T binding

    Biotechnology Journal

    Volume 7, Issue 1, January 2012, Pages: 127–132, Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer and Prof. Bernhardt L. Trout

    Version of Record online : 21 NOV 2011, DOI: 10.1002/biot.201100366

  17. Interspecies Scaling of Therapeutic Monoclonal Antibodies: Initial Look

    The Journal of Clinical Pharmacology

    Volume 49, Issue 12, December 2009, Pages: 1382–1402, Jie Ling, Honghui Zhou, Qun Jiao and Hugh M. Davis

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009337134

  18. You have full text access to this Open Access content
    Development of novel humanized anti-CD20 antibodies based on affinity constant and epitope

    Cancer Science

    Volume 101, Issue 1, January 2010, Pages: 201–209, Susumu Uchiyama, Yasuhiko Suzuki, Kentaro Otake, Masami Yokoyama, Mitsuo Ohta, Shuichi Aikawa, Midori Komatsu, Tetsuji Sawada, Yoshitoyo Kagami, Yasuo Morishima and Kiichi Fukui

    Version of Record online : 10 OCT 2009, DOI: 10.1111/j.1349-7006.2009.01392.x

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    Suppression of blastogenesis and proliferation of activated CD4+T cells: intravenous immunoglobulin (IVIg) versus novel anti-human leucocyte antigen (HLA)-E monoclonal antibodies mimicking HLA-I reactivity of IVIg

    Clinical & Experimental Immunology

    Volume 178, Issue 1, October 2014, Pages: 154–177, M. H. Ravindranath, P. I. Terasaki, T. Pham, V. Jucaud and S. Kawakita

    Version of Record online : 4 SEP 2014, DOI: 10.1111/cei.12391

  20. You have free access to this content
    Screening and characterization of monoclonal antibodies to the surface antigens of Listeria monocytogenes serotype 4b

    Journal of Applied Microbiology

    Volume 106, Issue 5, May 2009, Pages: 1705–1714, M. Lin, S. Armstrong, J. Ronholm, H. Dan, M.-E. Auclair, Z. Zhang and X. Cao

    Version of Record online : 16 FEB 2009, DOI: 10.1111/j.1365-2672.2008.04140.x