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There are 12306 results for: content related to: The identification of free cysteine residues within antibodies and a potential role for free cysteine residues in covalent aggregation because of agitation stress

  1. You have free access to this content
    Increased aggregation propensity of IgG2 subclass over IgG1: Role of conformational changes and covalent character in isolated aggregates

    Protein Science

    Volume 19, Issue 9, September 2010, Pages: 1601–1615, Heather Franey, Stephen R. Brych, Carl G. Kolvenbach and Rahul S. Rajan

    Version of Record online : 15 JUN 2010, DOI: 10.1002/pro.434

  2. Characterization of Cysteine-Linked Conjugation Profiles of Immunoglobulin G1 and Immunoglobulin G2 Antibody–Drug Conjugates

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 4, April 2015, Pages: 1362–1372, Brian Wiggins, Lily Liu-Shin, Hideto Yamaguchi and Gayathri Ratnaswamy

    Version of Record online : 28 JAN 2015, DOI: 10.1002/jps.24338

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    Protected hinge in the immunoglobulin G2-A2 disulfide isoform

    Protein Science

    Volume 23, Issue 12, December 2014, Pages: 1753–1764, Yaoqing Diana Liu, Robert Y.-T. Chou, Thomas M. Dillon, Leszek Poppe, Chris Spahr, Stone D. H. Shi and Gregory C. Flynn

    Version of Record online : 23 OCT 2014, DOI: 10.1002/pro.2557

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    Mutations within a human IgG2 antibody form distinct and homogeneous disulfide isomers but do not affect Fc gamma receptor or C1q binding

    Protein Science

    Volume 19, Issue 4, April 2010, Pages: 753–762, Sandra Lightle, Serdar Aykent, Nathan Lacher, Vesselin Mitaksov, Kristine Wells, James Zobel and Theodore Oliphant

    Version of Record online : 29 JAN 2010, DOI: 10.1002/pro.352

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    Conformational implications of an inversed pH-dependent antibody aggregation

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 9, September 2009, Pages: 3031–3042, Natalie Perico, Judith Purtell, Thomas M. Dillon and Margaret S. Ricci

    Version of Record online : 19 SEP 2008, DOI: 10.1002/jps.21539

  6. Cytokines and inflammatory factors regulating immunoglobulin production in aggressive periodontitis

    Periodontology 2000

    Volume 45, Issue 1, October 2007, Pages: 113–127, Harvey A. Schenkein, Suzanne E. Barbour and John G. Tew

    Version of Record online : 10 SEP 2007, DOI: 10.1111/j.1600-0757.2007.00214.x

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    Identification of the linear epitope for Fc-binding on the bovine IgG2 Fc receptor (boFcγ2R) using synthetic peptides

    FEBS Letters

    Volume 580, Issue 5, February 20, 2006, Pages: 1383–1390, Gaiping Zhang, Junqing Guo, Jiyong Zhou, Xuannian Wang, Qingmei Li, Yanyan Yang, Huigang Shen, Dong Zhao, Hua Zhang, Jun Xi, Li Wang, Songlin Qiao and Xin Jin

    Version of Record online : 26 JAN 2006, DOI: 10.1016/j.febslet.2006.01.060

  8. IgG2 containing IgM–IgG immune complexes predominate in normal human plasma, but not in plasma of patients with warm autoimmune haemolytic anaemia

    European Journal of Haematology

    Volume 77, Issue 3, September 2006, Pages: 191–202, Dorothea Stahl and Walter Sibrowski

    Version of Record online : 23 MAY 2006, DOI: 10.1111/j.1600-0609.2006.00691.x

  9. Serum IgG1 and IgG2 antibody responses to Porphyromonas gingivalis in patients with periodontitis

    Oral Microbiology and Immunology

    Volume 21, Issue 2, April 2006, Pages: 93–99, V. Booth, Ö. Solakoglu, N. Bavisha and M. A. Curtis

    Version of Record online : 13 FEB 2006, DOI: 10.1111/j.1399-302X.2006.00265.x

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    FcRn binding is not sufficient for achieving systemic therapeutic levels of immunoglobulin G after oral delivery of enteric-coated capsules in cynomolgus macaques

    Pharmacology Research & Perspectives

    Volume 4, Issue 3, June 2016, Salman Muzammil, John R. Mabus, Philip R. Cooper, Randall J. Brezski, Courtney B. Bement, Rob Perkinson, Norman D. Huebert, Suzanne Thompson, Dalia Levine, Connie Kliwinski, Dino Bradley and Pamela J. Hornby

    Version of Record online : 25 APR 2016, DOI: 10.1002/prp2.218

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    Sorbitol Crystallization-Induced Aggregation in Frozen mAb Formulations

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 2, February 2015, Pages: 686–697, Deirdre Murphy Piedmonte, Alison Hair, Priti Baker, Lejla Brych, Karthik Nagapudi, Hong Lin, Wenjin Cao, Susan Hershenson and Gayathri Ratnaswamy

    Version of Record online : 12 SEP 2014, DOI: 10.1002/jps.24141

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    Elucidation of two major aggregation pathways in an IgG2 antibody

    Journal of Pharmaceutical Sciences

    Volume 98, Issue 9, September 2009, Pages: 3013–3030, Nicholas Van Buren, Douglas Rehder, Himanshu Gadgil, Masazumi Matsumura and Jaby Jacob

    Version of Record online : 4 AUG 2008, DOI: 10.1002/jps.21514

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    The use of native cation-exchange chromatography to study aggregation and phase separation of monoclonal antibodies

    Protein Science

    Volume 19, Issue 6, June 2010, Pages: 1191–1204, Shuang Chen, Hollis Lau, Yan Brodsky, Gerd R. Kleemann and Ramil F. Latypov

    Version of Record online : 13 APR 2010, DOI: 10.1002/pro.396

  14. Rapid and refined separation of human IgG2 disulfide isomers using superficially porous particles

    Journal of Separation Science

    Volume 33, Issue 17-18, September 2010, Pages: 2671–2680, Qian Wang, Nathan A. Lacher, Bilikallahalli K. Muralidhara, Michael R. Schlittler, Serdar Aykent and Charles W. Demarest

    Version of Record online : 20 AUG 2010, DOI: 10.1002/jssc.201000230

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    Understanding the relevance of local conformational stability and dynamics to the aggregation propensity of an IgG1 and IgG2 monoclonal antibodies

    Protein Science

    Volume 22, Issue 10, October 2013, Pages: 1295–1305, Santosh V. Thakkar, Neha Sahni, Sangeeta B. Joshi, Bruce A. Kerwin, Feng He, David B. Volkin and C. Russell Middaugh

    Version of Record online : 18 AUG 2013, DOI: 10.1002/pro.2316

  16. Studies on the binding sites of IgG2 monoclonal antibodies recognized by terpyridine-based affinity ligands

    Journal of Molecular Recognition

    Volume 29, Issue 7, July 2016, Pages: 334–342, Chih-Pei Lin, Reinhard I. Boysen, Eva M. Campi, Kei Saito and Milton T. W. Hearn

    Version of Record online : 4 FEB 2016, DOI: 10.1002/jmr.2535

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    An application of ultraviolet spectroscopy to study interactions in proteins solutions at high concentrations

    Journal of Pharmaceutical Sciences

    Volume 101, Issue 9, September 2012, Pages: 3051–3061, Santosh V. Thakkar, Kevin M. Allegre, Sangeeta B. Joshi, David B. Volkin and C. Russell Middaugh

    Version of Record online : 11 MAY 2012, DOI: 10.1002/jps.23188

  18. Immunoglobulin G profiles in different forms of periodontitis

    Journal of Periodontal Research

    Volume 38, Issue 5, October 2003, Pages: 471–476, Hsien-Yang Chung, Hsi-Chi Lu, Woan-Ling Chen, Chun-Tai Lu, Yi-Hsin Yang and Chi-Cheng Tsai

    Version of Record online : 27 AUG 2003, DOI: 10.1034/j.1600-0765.2003.00675.x

  19. IgG Subclass Specificity Discriminates Restricted IgM Rheumatoid Factor Responses From More Mature Anti–Citrullinated Protein Antibody–Associated or Isotype-Switched IgA Responses

    Arthritis & Rheumatology

    Volume 67, Issue 12, December 2015, Pages: 3124–3134, Willem J. J. Falkenburg, Dirkjan van Schaardenburg, Pleuni Ooijevaar-de Heer, Gertjan Wolbink and Theo Rispens

    Version of Record online : 25 NOV 2015, DOI: 10.1002/art.39299

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    IgG Subclasses Against Helicobacter pylori Isolates: An important Tool for Disease Characterization

    Scandinavian Journal of Immunology

    Volume 76, Issue 1, July 2012, Pages: 26–32, F. Martínez-Becerra, G. Castillo-Rojas, S. Ponce de León and Y. López-Vidal*

    Version of Record online : 12 JUN 2012, DOI: 10.1111/j.1365-3083.2012.02699.x