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There are 5384 results for: content related to: Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation

  1. Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice


    Volume 62, Issue 2, August 2015, Pages: 534–545, Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Article first published online : 3 JUN 2015, DOI: 10.1002/hep.27859

  2. You have full text access to this Open Access content
    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Article first published online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x

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    Sorafenib, a multikinase inhibitor, is effective in vitro against non-hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin

    American Journal of Hematology

    Volume 87, Issue 3, March 2012, Pages: 277–283, Vijay Ramakrishnan, Michael Timm, Jessica L. Haug, Teresa K. Kimlinger, Timothy Halling, Linda E. Wellik, Thomas E. Witzig, S. Vincent Rajkumar, Alex A. Adjei and Shaji Kumar

    Article first published online : 21 DEC 2011, DOI: 10.1002/ajh.22263

  4. Effects of Antitumor Drug Sorafenib on Chick Embryo Development

    The Anatomical Record

    Volume 298, Issue 7, July 2015, Pages: 1271–1281, Yi-Sen Cheng, Xiao-Yu Wang, Guang Wang, Yan Li, Yue-Lei Chen, Man-li Chuai, Kenneth Ka Ho Lee, Xiao-Yan Ding and Xue-song Yang

    Article first published online : 17 APR 2015, DOI: 10.1002/ar.23155

  5. You have full text access to this OnlineOpen article
    Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

    International Journal of Cancer

    Volume 136, Issue 6, 15 March 2015, Pages: 1434–1444, Floris H. Groenendijk, Wouter W. Mellema, Eline van der Burg, Eva Schut, Michael Hauptmann, Hugo M. Horlings, Stefan M. Willems, Michel M. van den Heuvel, Jos Jonkers, Egbert F. Smit and René Bernards

    Article first published online : 8 AUG 2014, DOI: 10.1002/ijc.29113

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    A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

    BJU International

    Volume 107, Issue 8, April 2011, Pages: 1190–1199, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders and Camillo Porta

    Article first published online : 15 NOV 2010, DOI: 10.1111/j.1464-410X.2010.09829.x

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    ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21(CIP1/WAF1) in human cancer cells

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3182–3195, Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu and Wenhua Li

    Article first published online : 10 JUN 2014, DOI: 10.1111/bph.12659

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib


    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Article first published online : 27 AUG 2012, DOI: 10.1002/hep.25872

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    Sorafenib relieves cell-intrinsic and cell-extrinsic inhibitions of effector T cells in tumor microenvironment to augment antitumor immunity

    International Journal of Cancer

    Volume 134, Issue 2, 15 January 2014, Pages: 319–331, Mei-Ling Chen, Bo-Shiun Yan, Wan-Chih Lu, Mei-Huei Chen, Sung-Liang Yu, Pan-Chyr Yang and Ann-Lii Cheng

    Article first published online : 30 JUL 2013, DOI: 10.1002/ijc.28362

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2


    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Article first published online : 5 AUG 2009, DOI: 10.1002/hep.23214

  11. Effect of treatment with branched-chain amino acids during sorafenib therapy for unresectable hepatocellular carcinoma

    Hepatology Research

    Volume 44, Issue 3, March 2014, Pages: 302–312, Haruhiko Takeda, Hiroki Nishikawa, Eriko Iguchi, Yoshiaki Ohara, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Ryuichi Kita, Toru Kimura and Yukio Osaki

    Article first published online : 29 APR 2013, DOI: 10.1111/hepr.12125

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    Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal-regulated kinase counteraction

    The FEBS Journal

    Volume 278, Issue 18, September 2011, Pages: 3494–3507, Irena Manov, Yulia Pollak, Rinata Broneshter and Theodore C. Iancu

    Article first published online : 5 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08271.x

  13. Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma

    Molecular Carcinogenesis

    Volume 52, Issue 1, January 2013, Pages: 39–48, Rit Vatsyayan, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi and Sharad S. Singhal

    Article first published online : 17 OCT 2011, DOI: 10.1002/mc.20875

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    Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

    International Journal of Cancer

    Volume 131, Issue 3, 1 August 2012, Pages: 548–557, Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita, Takahiro Kodama, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Naonobu Fujita, Tamotsu Yoshimori and Norio Hayashi

    Article first published online : 12 SEP 2011, DOI: 10.1002/ijc.26374

  15. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Article first published online : 11 JUN 2013, DOI: 10.1002/jcb.24530

  16. Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli

    Journal of Cellular Physiology

    Volume 227, Issue 4, April 2012, Pages: 1319–1325, Joan Fernando, Patricia Sancho, Conrado M. Fernández-Rodriguez, José L. Lledó, Laia Caja, Jean S. Campbell, Nelson Fausto and Isabel Fabregat

    Article first published online : 11 JAN 2012, DOI: 10.1002/jcp.22843

  17. Phase I Trial of Sorafenib in Combination With 5-Fluorouracil/Leucovorin in Advanced Solid Tumors

    The Journal of Clinical Pharmacology

    Volume 52, Issue 5, May 2012, Pages: 656–669, Dr Einat Shacham-Shmueli, Dr Ravit Geva, Dr Arie Figer, Dr Sarah Bulocinic, Dr Karen Nalbandyan, Dr Shulim Shpigel, Dr Jacob Atsmon and Dr Erich Brendel

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270011404027

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    Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells


    Volume 57, Issue 6, June 2013, Pages: 2358–2368, Martin Franz Sprinzl, Florian Reisinger, Andreas Puschnik, Marc Ringelhan, Kerstin Ackermann, Daniel Hartmann, Matthias Schiemann, Arndt Weinmann, Peter Robert Galle, Marcus Schuchmann, Helmut Friess, Gerd Otto, Mathias Heikenwalder and Ulrike Protzer

    Article first published online : 12 JUN 2013, DOI: 10.1002/hep.26328

  19. Inhibition of myeloid cell leukemia-1: Association with sorafenib-induced apoptosis in human mucoepidermoid carcinoma cells and tumor xenograft

    Head & Neck

    Volume 37, Issue 9, September 2015, Pages: 1326–1335, Hyun-Ju Yu, Ji-Ae Shin, Ji-Youn Jung, Jeong-Seok Nam, In-Sun Hong, Nam-Pyo Cho and Sung-Dae Cho

    Article first published online : 19 JUL 2014, DOI: 10.1002/hed.23749

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Article first published online : 30 APR 2012, DOI: 10.1002/ijc.27604