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There are 11975 results for: content related to: Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry

  1. Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

    Histopathology

    Volume 38, Issue 2, February 2001, Pages: 120–134, M R D'Andrea, R G Nagele, H-Y Wang, P A Peterson and D H S Lee

    Version of Record online : 21 DEC 2001, DOI: 10.1046/j.1365-2559.2001.01082.x

  2. You have free access to this content
    The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway

    The FEBS Journal

    Volume 281, Issue 11, June 2014, Pages: 2674–2687, Yu-Jen Chang and Yun-Ru Chen

    Version of Record online : 6 MAY 2014, DOI: 10.1111/febs.12813

  3. You have free access to this content
    Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

    Journal of Neurochemistry

    Volume 126, Issue 3, August 2013, Pages: 305–311, Lei Gu and Zhefeng Guo

    Version of Record online : 12 MAR 2013, DOI: 10.1111/jnc.12202

  4. Identification of Physiological and Toxic Conformations in Aβ42 Aggregates

    ChemBioChem

    Volume 10, Issue 2, January 26, 2009, Pages: 287–295, Yuichi Masuda, Satoko Uemura, Ryutaro Ohashi, Azusa Nakanishi, K. Takegoshi, Takahiko Shimizu, Takuji Shirasawa and Kazuhiro Irie

    Version of Record online : 29 DEC 2008, DOI: 10.1002/cbic.200800411

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    Docosahexaenoic acid stabilizes soluble amyloid-β protofibrils and sustains amyloid-β-induced neurotoxicity in vitro

    The FEBS Journal

    Volume 274, Issue 4, February 2007, Pages: 990–1000, Ann-Sofi Johansson, Anita Garlind, Fredrik Berglind-Dehlin, Göran Karlsson, Katarina Edwards, Pär Gellerfors, Frida Ekholm-Pettersson, Jan Palmblad and Lars Lannfelt

    Version of Record online : 12 JAN 2007, DOI: 10.1111/j.1742-4658.2007.05647.x

  6. You have full text access to this OnlineOpen article
    Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 4, April 2012, Pages: 344–352, Nobuto Kakuda, Mikio Shoji, Hiroyuki Arai, Katsutoshi Furukawa, Takeshi Ikeuchi, Kohei Akazawa, Mako Takami, Hiroyuki Hatsuta, Shigeo Murayama, Yasuhiro Hashimoto, Masakazu Miyajima, Hajime Arai, Yu Nagashima, Haruyasu Yamaguchi, Ryozo Kuwano, Kazuhiro Nagaike, Yasuo Ihara and the Japanese Alzheimer's Disease Neuroimaging Initiative

    Version of Record online : 21 FEB 2012, DOI: 10.1002/emmm.201200214

  7. Age and amyloid effects on human central nervous system amyloid-beta kinetics

    Annals of Neurology

    Volume 78, Issue 3, September 2015, Pages: 439–453, Bruce W. Patterson, Donald L. Elbert, Kwasi G. Mawuenyega, Tom Kasten, Vitaliy Ovod, Shengmei Ma, Chengjie Xiong, Robert Chott, Kevin Yarasheski, Wendy Sigurdson, Lily Zhang, Alison Goate, Tammie Benzinger, John C. Morris, David Holtzman and Randall J. Bateman

    Version of Record online : 20 JUL 2015, DOI: 10.1002/ana.24454

  8. Disclosure of a fundamental clue for the elucidation of the myricetin mechanism of action as amyloid aggregation inhibitor by mass spectrometry

    ELECTROPHORESIS

    Volume 33, Issue 22, November 2012, Pages: 3380–3386, Jessica Fiori, Marina Naldi, Manuela Bartolini and Vincenza Andrisano

    Version of Record online : 10 SEP 2012, DOI: 10.1002/elps.201200186

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    The correlation between neurotoxicity, aggregative ability and secondary structure studied by sequence truncated Aβ peptides

    FEBS Letters

    Volume 581, Issue 6, March 20, 2007, Pages: 1161–1165, M.Q. Liao, Y.J. Tzeng, Lea Y.X. Chang, H.B. Huang, T.H. Lin, C.L. Chyan and Y.C. Chen

    Version of Record online : 20 FEB 2007, DOI: 10.1016/j.febslet.2007.02.026

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    Isobavachalcone and bavachinin from Psoraleae Fructus modulate Aβ42 aggregation process through different mechanisms in vitro

    FEBS Letters

    Volume 587, Issue 18, September 17, 2013, Pages: 2930–2935, Xiumin Chen, Yanfang Yang and Yingtao Zhang

    Version of Record online : 29 JUL 2013, DOI: 10.1016/j.febslet.2013.07.037

  11. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

  12. (R)-α-trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillation

    Peptide Science

    Volume 104, Issue 5, September 2015, Pages: 601–610, Alexandra Botz, Vincent Gasparik, Emmanuelle Devillers, Anais R. F. Hoffmann, Lucie Caillon, Evelyne Chelain, Olivier Lequin, Thierry Brigaud and Lucie Khemtemourian

    Version of Record online : 24 SEP 2015, DOI: 10.1002/bip.22670

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    Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility

    Protein Science

    Volume 18, Issue 2, February 2009, Pages: 277–286, Li Ling Lee, HyungHo Ha, Young-Tae Chang and Matthew P. DeLisa

    Version of Record online : 15 DEC 2008, DOI: 10.1002/pro.33

  14. β-amyloid peptide is internalized into chick retinal neurons and alters the distribution of myosin Vb

    Cytoskeleton

    Volume 69, Issue 3, March 2012, Pages: 166–178, Leandro T. Oliveira, Priscila A. Matos, David William Provance Jr., Fernando G. de Mello, Leonardo R. Andrade, Martha M. Sorenson and Verônica P. Salerno

    Version of Record online : 3 FEB 2012, DOI: 10.1002/cm.21007

  15. Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis-block micronucleus cytome assay

    Environmental and Molecular Mutagenesis

    Volume 55, Issue 1, January 2014, Pages: 1–14, Sau Lai Lee, Philip Thomas and Michael Fenech

    Version of Record online : 28 AUG 2013, DOI: 10.1002/em.21811

  16. Distance Measurement between Tyr10 and Met35 in Amyloid β by Site-Directed Spin-Labeling ESR Spectroscopy: Implications for the Stronger Neurotoxicity of Aβ42 than Aβ40

    ChemBioChem

    Volume 8, Issue 18, December 17, 2007, Pages: 2308–2314, Kazuma Murakami, Hideyuki Hara, Yuichi Masuda, Hajime Ohigashi and Kazuhiro Irie

    Version of Record online : 19 NOV 2007, DOI: 10.1002/cbic.200700240

  17. You have full text access to this OnlineOpen article
    Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations

    FEBS Open Bio

    Volume 4, Issue 1, January 01, 2014, Pages: 393–406, Johanna Wanngren, Patricia Lara, Karin Öjemalm, Silvia Maioli, Nasim Moradi, Lu Chen, Lars O. Tjernberg, Johan Lundkvist, IngMarie Nilsson and Helena Karlström

    Version of Record online : 24 APR 2014, DOI: 10.1016/j.fob.2014.04.006

  18. Visinin-like protein-1: Diagnostic and prognostic biomarker in Alzheimer disease

    Annals of Neurology

    Volume 70, Issue 2, August 2011, Pages: 274–285, Rawan Tarawneh, Gina D'Angelo, Elizabeth Macy, Chengjie Xiong, Deborah Carter, Nigel J. Cairns, Anne M. Fagan, Denise Head, Mark A. Mintun, Jack H. Ladenson, Jin-Moo Lee, John C. Morris and David M. Holtzman

    Version of Record online : 5 AUG 2011, DOI: 10.1002/ana.22448

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    Despite its role in assembly, methionine 35 is not necessary for amyloid β-protein toxicity

    Journal of Neurochemistry

    Volume 113, Issue 5, June 2010, Pages: 1252–1262, Panchanan Maiti, Aleksey Lomakin, George B. Benedek and Gal Bitan

    Version of Record online : 20 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06692.x

  20. Retro-Enantio N-Methylated Peptides as β-Amyloid Aggregation Inhibitors

    ChemMedChem

    Volume 4, Issue 9, September 4, 2009, Pages: 1488–1494, Dolors Grillo-Bosch, Natàlia Carulla, Montse Cruz, Laia Sánchez, Rosa Pujol-Pina, Sergio Madurga, Francesc Rabanal and Ernest Giralt

    Version of Record online : 9 JUL 2009, DOI: 10.1002/cmdc.200900191