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There are 7827 results for: content related to: Crossroads in GDNF therapy for Parkinson's disease

  1. Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model

    The Journal of Gene Medicine

    Volume 11, Issue 10, October 2009, Pages: 899–912, Xin Yang, Birgit Mertens, Enni Lehtonen, Linda Vercammen, Olivier Bockstael, Abdelwahed Chtarto, Marc Levivier, Jacques Brotchi, Yvette Michotte, Veerle Baekelandt, Sophie Sarre and Liliane Tenenbaum

    Article first published online : 28 JUL 2009, DOI: 10.1002/jgm.1377

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    Gdnf Upregulates c-Fos Transcription via the Ras/Erk1/2 Pathway to Promote Mouse Spermatogonial Stem Cell Proliferation

    STEM CELLS

    Volume 26, Issue 1, January 2008, Pages: 266–278, Zuping He, Jiji Jiang, Maria Kokkinaki, Nady Golestaneh, Marie-Claude Hofmann and Martin Dym

    Article first published online : 25 OCT 2007, DOI: 10.1634/stemcells.2007-0436

  3. GDNF-enhanced axonal regeneration and myelination following spinal cord injury is mediated by primary effects on neurons

    Glia

    Volume 57, Issue 11, 15 August 2009, Pages: 1178–1191, Liqun Zhang, Zhengwen Ma, George M. Smith, Xuejun Wen, Yelena Pressman, Patrick M. Wood and Xiao-Ming Xu

    Article first published online : 23 JAN 2009, DOI: 10.1002/glia.20840

  4. Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse

    Addiction Biology

    Segev Barak, Jun Wang, Somayeh Ahmadiantehrani, Sami Ben Hamida, Adrian P. Kells, John Forsayeth, Krystof S. Bankiewicz and Dorit Ron

    Article first published online : 6 MAY 2014, DOI: 10.1111/adb.12152

  5. Controlled release of glial-derived neurotrophic factor from fibrin matrices containing an affinity-based delivery system

    Journal of Biomedical Materials Research Part A

    Volume 89A, Issue 4, 15 June 2009, Pages: 909–918, Matthew D. Wood, Gregory H. Borschel and Shelly E. Sakiyama-Elbert

    Article first published online : 8 MAY 2008, DOI: 10.1002/jbm.a.32043

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    Long-term expression of glial cell line-derived neurotrophic factor slows, but does not stop retinal degeneration in a model of retinitis pigmentosa

    Journal of Neurochemistry

    Volume 122, Issue 5, September 2012, Pages: 1047–1053, Masayuki Ohnaka, Katsuaki Miki, Yuan-Yuan Gong, Rebecca Stevens, Takeshi Iwase, Sean F. Hackett and Peter A. Campochiaro

    Article first published online : 23 JUL 2012, DOI: 10.1111/j.1471-4159.2012.07842.x

  7. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

    European Journal of Neuroscience

    Volume 22, Issue 11, December 2005, Pages: 2755–2764, Cecilia Ericson, Biljana Georgievska and Cecilia Lundberg

    Article first published online : 29 NOV 2005, DOI: 10.1111/j.1460-9568.2005.04503.x

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    Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells

    Journal of Neurochemistry

    Volume 94, Issue 6, September 2005, Pages: 1488–1499, T. Iwase, C. G. Jung, H. Bae, M. Zhang and B. Soliven

    Article first published online : 8 AUG 2005, DOI: 10.1111/j.1471-4159.2005.03290.x

  9. Prenatal LPS increases Inflammation in the Substantia Nigra of Gdnf Heterozygous Mice

    Brain Pathology

    Volume 21, Issue 3, May 2011, Pages: 330–348, Ann-Charlotte Granholm, Vandana Zaman, Jennifer Godbee, Michael Smith, Riad Ramadan, Claudia Umphlet, Patrick Randall, Narayan R. Bhat, Baerbel Rohrer, Lawrence D. Middaugh and Heather A. Boger

    Article first published online : 8 DEC 2010, DOI: 10.1111/j.1750-3639.2010.00457.x

  10. Activation of microglia by endotoxin suppresses the secretion of glial cell line–derived neurotrophic factor (GDNF) through the action of protein kinase Cα (PKCα) and mitogen-activated protein kinases (MAPKS)

    Journal of Neuroscience Research

    Volume 86, Issue 9, July 2008, Pages: 1959–1971, Yuichi Matsushita, Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara and Shinichi Kohsaka

    Article first published online : 25 APR 2008, DOI: 10.1002/jnr.21657

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    Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells

    Journal of Neurochemistry

    Volume 79, Issue 1, October 2001, Pages: 25–34, Kazue Hisaoka, Akira Nishida, Tetsuzo Koda, Masahiko Miyata, Hidenobu Zensho, Shigeru Morinobu, Mitsuhiro Ohta and Shigeto Yamawaki

    Article first published online : 7 JUL 2008, DOI: 10.1046/j.1471-4159.2001.00531.x

  12. Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

    European Journal of Neuroscience

    Volume 12, Issue 11, November 2000, Pages: 3871–3882, Deniz Kirik, Carl Rosenblad and Anders Björklund

    Article first published online : 9 OCT 2008, DOI: 10.1046/j.1460-9568.2000.00274.x

  13. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination

    Journal of Comparative Neurology

    Volume 467, Issue 3, 15 December 2003, Pages: 403–417, Armin Blesch and Mark H. Tuszynski

    Article first published online : 3 NOV 2003, DOI: 10.1002/cne.10934

  14. Adult neural stem and progenitor cells modified to secrete GDNF can protect, migrate and integrate after intracerebral transplantation in rats with transient forebrain ischemia

    European Journal of Neuroscience

    Volume 26, Issue 6, September 2007, Pages: 1462–1478, M. Kameda, T. Shingo, K. Takahashi, K. Muraoka, K. Kurozumi, T. Yasuhara, T. Maruo, T. Tsuboi, T. Uozumi, T. Matsui, Y. Miyoshi, H. Hamada and I. Date

    Article first published online : 14 SEP 2007, DOI: 10.1111/j.1460-9568.2007.05776.x

  15. Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson's disease with Trojan horse liposomes and a tyrosine hydroxylase promoter

    The Journal of Gene Medicine

    Volume 10, Issue 3, March 2008, Pages: 306–315, Chun-Fang Xia, Ruben J. Boado, Yun Zhang, Chun Chu and William M. Pardridge

    Article first published online : 18 DEC 2007, DOI: 10.1002/jgm.1152

  16. Glial-derived neurotrophic factor regulates intestinal epithelial barrier function and inflammation and is therapeutic for murine colitis

    The Journal of Pathology

    Volume 222, Issue 2, October 2010, Pages: 213–222, Dei Kui Zhang, Fu Qian He, Tian Ke Li, Xue Hua Pang, De Jun Cui, Qin Xie, Xiao Li Huang and Hua Tian Gan

    Article first published online : 17 JUN 2010, DOI: 10.1002/path.2749

  17. In vivo gene delivery of glial cell line–derived neurotrophic factor for Parkinson's disease

    Annals of Neurology

    Volume 53, Issue S3, 2003, Pages: S120–S134, Jeffrey H. Kordower

    Article first published online : 24 MAR 2003, DOI: 10.1002/ana.10485

  18. Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve

    European Journal of Neuroscience

    Volume 28, Issue 8, October 2008, Pages: 1467–1479, Martijn R. Tannemaat, Ruben Eggers, William T. Hendriks, Godard C. W. De Ruiter, Joop J. Van Heerikhuize, Chris W. Pool, Martijn J. A. Malessy, Gerard J. Boer and Joost Verhaagen

    Article first published online : 7 OCT 2008, DOI: 10.1111/j.1460-9568.2008.06452.x

  19. Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells

    CNS Neuroscience & Therapeutics

    Volume 20, Issue 11, November 2014, Pages: 961–972, Susana Revilla, Suzanna Ursulet, María Jesús Álvarez-López, Marco Castro-Freire, Unai Perpiñá, Yoelvis García-Mesa, Analía Bortolozzi, Lydia Giménez-Llort, Perla Kaliman, Rosa Cristòfol, Chamsy Sarkis and Coral Sanfeliu

    Article first published online : 13 AUG 2014, DOI: 10.1111/cns.12312

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    Gdnf is mitogenic, neurotrophic, and chemoattractive to enteric neural crest cells in the embryonic colon

    Developmental Dynamics

    Volume 240, Issue 6, June 2011, Pages: 1402–1411, Olive Mwizerwa, Pragnya Das, Nandor Nagy, Sophia E. Akbareian, John D. Mably and Allan M. Goldstein

    Article first published online : 4 APR 2011, DOI: 10.1002/dvdy.22630