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There are 32934 results for: content related to: A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

  1. Animal and human studies with the mitochondria-targeted antioxidant MitoQ

    Annals of the New York Academy of Sciences

    Volume 1201, Issue 1, July 2010, Pages: 96–103, Robin A.J. Smith and Michael P. Murphy

    Article first published online : 21 JUL 2010, DOI: 10.1111/j.1749-6632.2010.05627.x

  2. Prevention of gentamicin-induced apoptosis with the mitochondria-targeted antioxidant mitoquinone

    The Laryngoscope

    Volume 122, Issue 11, November 2012, Pages: 2543–2548, Carolyn P. Ojano-Dirain and Patrick J. Antonelli

    Article first published online : 10 SEP 2012, DOI: 10.1002/lary.23593

  3. Neonatal rat hypoxia–ischemia: Effect of the anti-oxidant mitoquinol, and S-PBN

    Pediatrics International

    Volume 50, Issue 4, August 2008, Pages: 481–488, Catherine E. Hobbs, 1 Michael P. Murphy, 3 Robin A.J. Smith and 2 Dorothy E. Oorschot 1

    Article first published online : 25 AUG 2008, DOI: 10.1111/j.1442-200X.2008.02705.x

  4. Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

    The Journal of Physiology

    Volume 592, Issue 12, 15 June 2014, Pages: 2549–2561, Rachel A. Gioscia-Ryan, Thomas J. LaRocca, Amy L. Sindler, Melanie C. Zigler, Michael P. Murphy and Douglas R. Seals

    Article first published online : 23 APR 2014, DOI: 10.1113/jphysiol.2013.268680

  5. You have full text access to this OnlineOpen article
    Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis

    Hepatology

    Volume 54, Issue 1, July 2011, Pages: 153–163, Balu K. Chacko, Anup Srivastava, Michelle S. Johnson, Gloria A. Benavides, Mi Jung Chang, Yaozu Ye, Nirag Jhala, Michael P. Murphy, Balaraman Kalyanaraman and Victor M. Darley-Usmar

    Article first published online : 24 JUN 2011, DOI: 10.1002/hep.24377

  6. Mitochondria-Targeted Antioxidants in the Treatment of Disease

    Annals of the New York Academy of Sciences

    Volume 1147, Issue 1, December 2008, Pages: 105–111, Robin A.J. Smith, Victoria J. Adlam, Frances H. Blaikie, Abdul-Rahman B. Manas, Carolyn M. Porteous, Andrew M. James, Meredith F. Ross, Angela Logan, Helena M. Cochemé, Jan Trnka, Tracy A. Prime, Irina Abakumova, Bruce A. Jones, Aleksandra Filipovska and Michael P. Murphy

    Article first published online : 8 DEC 2008, DOI: 10.1196/annals.1427.003

  7. Prevention of Mitochondrial Oxidative Damage Using Targeted Antioxidants

    Annals of the New York Academy of Sciences

    Volume 959, Issue 1, April 2002, Pages: 263–274, GEOFFREY F. KELSO, CAROLYN M. PORTEOUS, GILLIAN HUGHES, ELIZABETH C. LEDGERWOOD, ALISON M. GANE, ROBIN A. J. SMITH and MICHAEL P. MURPHY

    Article first published online : 24 JAN 2006, DOI: 10.1111/j.1749-6632.2002.tb02098.x

  8. You have free access to this content
    Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes

    Medicinal Research Reviews

    Volume 34, Issue 1, January 2014, Pages: 160–189, Milagros Rocha, Nadezda Apostolova, Jose Raul Herance, Susana Rovira-Llopis, Antonio Hernandez-Mijares and Victor M. Victor

    Article first published online : 3 MAY 2013, DOI: 10.1002/med.21285

  9. Quantitation and metabolism of mitoquinone, a mitochondria-targeted antioxidant, in rat by liquid chromatography/tandem mass spectrometry

    Rapid Communications in Mass Spectrometry

    Volume 21, Issue 13, 15 July 2007, Pages: 1958–1964, Yan Li, Hu Zhang, J. Paul Fawcett and Ian G. Tucker

    Article first published online : 29 MAY 2007, DOI: 10.1002/rcm.3048

  10. Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartilage

    Journal of Orthopaedic Research

    Volume 31, Issue 2, February 2013, Pages: 191–196, Katherine J. Wolff, Prem S. Ramakrishnan, Marc J. Brouillette, Brice J. Journot, Todd O. Mckinley, Joseph A. Buckwalter and James A. Martin

    Article first published online : 28 AUG 2012, DOI: 10.1002/jor.22223

  11. The Mitochondrial Antioxidants MitoE2 and MitoQ10 Increase Mitochondrial Ca2+ Load upon Cell Stimulation by Inhibiting Ca2+ Efflux from the Organelle

    Annals of the New York Academy of Sciences

    Volume 1147, Issue 1, December 2008, Pages: 264–274, Sara Leo, György Szabadkai and Rosario Rizzuto

    Article first published online : 8 DEC 2008, DOI: 10.1196/annals.1427.019

  12. Role of mitochondrial reactive oxygen species in osteoclast differentiation

    Annals of the New York Academy of Sciences

    Volume 1192, Issue 1, April 2010, Pages: 245–252, Satish Srinivasan, Alexander Koenigstein, Joy Joseph, Li Sun, B. Kalyanaraman, Mone Zaidi and Narayan G. Avadhani

    Article first published online : 5 APR 2010, DOI: 10.1111/j.1749-6632.2009.05377.x

  13. You have open access to this content
    MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress

    Aging Cell

    Volume 2, Issue 2, April 2003, Pages: 141–143, Gabriele Saretzki, Michael P. Murphy and Thomas Von Zglinicki

    Article first published online : 26 MAR 2003, DOI: 10.1046/j.1474-9728.2003.00040.x

  14. Mitochondria-derived Reactive Oxygen Species Mediate Blue Light-induced Death of Retinal Pigment Epithelial Cells

    Photochemistry and Photobiology

    Volume 79, Issue 5, May 2004, Pages: 470–475, Ayala King, Eyal Gottlieb, David G. Brooks, Michael P. Murphy and Joshua L. Dunaief

    Article first published online : 1 MAY 2007, DOI: 10.1111/j.1751-1097.2004.tb00036.x

  15. You have full text access to this OnlineOpen article
    How to Clean the Dirtiest Place in the Cell: Cationic Antioxidants as Intramitochondrial ROS Scavengers

    IUBMB Life

    Volume 57, Issue 4-5, April 2005, Pages: 305–310, Vladimir P. Skulachev

    Article first published online : 3 JAN 2008, DOI: 10.1080/15216540500092161

  16. You have full text access to this OnlineOpen article
    Mitochondrial Reactive Oxygen Species Mediate Cardiomyocyte Formation from Embryonic Stem Cells in High Glucose

    STEM CELLS

    Volume 28, Issue 7, July 2010, Pages: 1132–1142, Francisco Luna Crespo, Veronica R. Sobrado, Laura Gomez, Ana M. Cervera and Kenneth J. McCreath

    Article first published online : 6 MAY 2010, DOI: 10.1002/stem.441

  17. You have free access to this content
    Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1917–1942, G C Higgins and M T Coughlan

    Article first published online : 28 MAR 2014, DOI: 10.1111/bph.12503

  18. Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis

    Journal of Pineal Research

    Volume 43, Issue 4, November 2007, Pages: 389–403, Mei-Jie Jou, Tsung-I Peng, Pai-Zu Yu, Shuo-Bin Jou, Russel J. Reiter, Jin-Yi Chen, Hong-Yueh Wu, Chih-Chun Chen and Lee-Fen Hsu

    Article first published online : 24 AUG 2007, DOI: 10.1111/j.1600-079X.2007.00490.x

  19. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

    Liver International

    Volume 30, Issue 7, August 2010, Pages: 1019–1026, Edward J. Gane, Frank Weilert, David W. Orr, Geraldine F. Keogh, Michael Gibson, Michelle M. Lockhart, Christopher M. Frampton, Kenneth M. Taylor, Robin A. J. Smith and Michael P. Murphy

    Article first published online : 18 MAY 2010, DOI: 10.1111/j.1478-3231.2010.02250.x

  20. Respiratory chain deficiency slows down cell-cycle progression via reduced ROS generation and is associated with a reduction of p21CIP1/WAF1

    Journal of Cellular Physiology

    Volume 209, Issue 1, October 2006, Pages: 103–112, Matthias Schauen, Dimitry Spitkovsky, Jens Schubert, Jürgen H. Fischer, Jun-Ichi Hayashi and Rudolf J. Wiesner

    Article first published online : 14 JUN 2006, DOI: 10.1002/jcp.20711