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There are 4379 results for: content related to: Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

  1. You have free access to this content
    Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms

    The Journal of Physiology

    Volume 569, Issue 2, December 2005, Pages: 519–531, Wei Yang, Guangdong Yang, Xuming Jia, Lingyun Wu and Rui Wang

    Version of Record online : 24 NOV 2005, DOI: 10.1113/jphysiol.2005.097642

  2. You have free access to this content
    Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis


    Volume 14, Issue 9, September 2013, Pages: 997–1013, Pei Zhi Cheryl Chia, Wei Hong Toh, Robyn Sharples, Isabelle Gasnereau, Andrew F. Hill and Paul A. Gleeson

    Version of Record online : 8 JUL 2013, DOI: 10.1111/tra.12088

  3. You have full text access to this OnlineOpen article
    Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant

    Brain and Behavior

    Volume 2, Issue 3, May 2012, Pages: 270–282, Kazumi Motoki, Hideaki Kume, Akiko Oda, Akira Tamaoka, Ai Hosaka, Fuyuki Kametani and Wataru Araki

    Version of Record online : 29 APR 2012, DOI: 10.1002/brb3.52

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    Physiological and behavioral effects of amphetamine in BACE1−/− mice

    Genes, Brain and Behavior

    Volume 14, Issue 5, June 2015, Pages: 411–418, R. Madelaine Paredes, E. Piccart, E. Navaira, D. Cruz, M. A. Javors, W. Koek, M. J. Beckstead and C. Walss-Bass

    Version of Record online : 21 MAY 2015, DOI: 10.1111/gbb.12222

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    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Version of Record online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

  6. Thapsigargin down-regulates protein levels of GRP78/BiP in INS-1E cells

    Journal of Cellular Biochemistry

    Volume 113, Issue 5, May 2012, Pages: 1635–1644, Victoria Rosengren, Henrik Johansson, Janne Lehtiö, Liselotte Fransson, Åke Sjöholm and Henrik Ortsäter

    Version of Record online : 15 MAR 2012, DOI: 10.1002/jcb.24032

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    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Version of Record online : 19 APR 2014, DOI: 10.1111/jnc.12715

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    Transcriptional and post-transcriptional regulation of β-secretase

    IUBMB Life

    Volume 64, Issue 12, December 2012, Pages: 943–950, Elena Tamagno, M. Guglielmotto, D. Monteleone, A. Vercelli and M. Tabaton

    Version of Record online : 26 NOV 2012, DOI: 10.1002/iub.1099

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    Activation of TRPV4 channel in pancreatic INS-1E beta cells enhances glucose-stimulated insulin secretion via calcium-dependent mechanisms

    FEBS Letters

    Volume 587, Issue 19, October 01, 2013, Pages: 3281–3287, M. Skrzypski, M. Kakkassery, S. Mergler, C. Grötzinger, N. Khajavi, M. Sassek, D. Szczepankiewicz, B. Wiedenmann, K.W. Nowak and M.Z. Strowski

    Version of Record online : 30 AUG 2013, DOI: 10.1016/j.febslet.2013.08.025

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    Identification of a cis-acting element involved in the regulation of BACE1 mRNA alternative splicing

    Journal of Neurochemistry

    Volume 109, Issue 4, May 2009, Pages: 1008–1016, Karen R. Mowrer and Michael S. Wolfe

    Version of Record online : 3 MAR 2009, DOI: 10.1111/j.1471-4159.2009.06026.x

  11. You have full text access to this Open Access content
    SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1018–1031, Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian and Giulio M. Pasinetti

    Version of Record online : 29 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00632.x

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    Uncoupling protein-2 mediates the protective action of berberine against oxidative stress in rat insulinoma INS-1E cells and in diabetic mouse islets

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3246–3254, Limei Liu, Jian Liu, Yuansheng Gao, Xiaoxing Yu, Gang Xu and Yu Huang

    Version of Record online : 10 JUN 2014, DOI: 10.1111/bph.12666

  13. Early activation of the fatty acid metabolism pathway by chronic high glucose exposure in rat insulin secretory β-cells


    Volume 10, Issue 1, No. 1 January 2010, Pages: 59–71, Yohann Couté, Yannick Brunner, Domitille Schvartz, Céline Hernandez, Alexandre Masselot, Frédérique Lisacek, Claes B. Wollheim and Jean-Charles Sanchez

    Version of Record online : 30 OCT 2009, DOI: 10.1002/pmic.200900080

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    Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting

    The FEBS Journal

    Volume 281, Issue 8, April 2014, Pages: 2074–2087, Bincy A. John, Melanie Meister, Antje Banning and Ritva Tikkanen

    Version of Record online : 6 MAR 2014, DOI: 10.1111/febs.12763

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    Role of cytosolic and calcium independent phospholipases A2 in insulin secretion impairment of INS-1E cells infected by S. aureus

    FEBS Letters

    Volume 589, Issue 24PartB, December 21, 2015, Pages: 3969–3976, N. Caporarello, M. Salmeri, M. Scalia, C. Motta, C. Parrino, L. Frittitta, M. Olivieri, M.A. Toscano, C.D. Anfuso and G. Lupo

    Version of Record online : 26 NOV 2015, DOI: 10.1016/j.febslet.2015.11.035

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    The microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretion

    FEBS Letters

    Volume 586, Issue 20, October 19, 2012, Pages: 3674–3680, Ying Ying, Lingyun Li, Wen Cao, Dan Yan, Qing Zeng, Xiangchen Kong, Lina Lu, Meng Yan, Xiaohui Xu, Junle Qu, Qingning Su and Xiaosong Ma

    Version of Record online : 6 SEP 2012, DOI: 10.1016/j.febslet.2012.08.025

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    β-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins

    The FEBS Journal

    Volume 277, Issue 6, March 2010, Pages: 1503–1518, Carlo Sala Frigerio, Julia V. Fadeeva, Aedín M. Minogue, Martin Citron, Fred Van Leuven, Matthias Staufenbiel, Paolo Paganetti, Dennis J. Selkoe and Dominic M. Walsh

    Version of Record online : 15 FEB 2010, DOI: 10.1111/j.1742-4658.2010.07579.x

  18. Promoter polymorphisms which modulate BACE1 expression are associated with sporadic Alzheimer's disease

    American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

    Volume 153B, Issue 1, January 2010, Pages: 159–166, Shan Wang and Jianping Jia

    Version of Record online : 13 MAY 2009, DOI: 10.1002/ajmg.b.30968

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    Altered β-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain

    FEBS Letters

    Volume 580, Issue 28-29, December 11, 2006, Pages: 6550–6560, John H. Stockley, Rivka Ravid and Cora O’Neill

    Version of Record online : 13 NOV 2006, DOI: 10.1016/j.febslet.2006.10.076

  20. You have free access to this content
    The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing

    Journal of Neurochemistry

    Volume 119, Issue 1, October 2011, Pages: 231–239, Sabine Rabe, Julia Reichwald, Domenico Ammaturo, Bart de Strooper, Paul Saftig, Ulf Neumann and Matthias Staufenbiel

    Version of Record online : 1 SEP 2011, DOI: 10.1111/j.1471-4159.2011.07412.x