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There are 4346 results for: content related to: Bone loss in survival motor neuron ( Smn −/− SMN2 ) genetic mouse model of spinal muscular atrophy

  1. Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy

    Journal of Neuroscience Research

    Volume 88, Issue 1, January 2010, Pages: 111–122, Hong Liu, Dina Shafey, Justin N. Moores and Rashmi Kothary

    Article first published online : 29 JUL 2009, DOI: 10.1002/jnr.22189

  2. Glucose metabolism and pancreatic defects in spinal muscular atrophy

    Annals of Neurology

    Volume 72, Issue 2, August 2012, Pages: 256–268, Melissa Bowerman, Kathryn J. Swoboda, John-Paul Michalski, Gen-Sheng Wang, Courtney Reeks, Ariane Beauvais, Kelley Murphy, John Woulfe, Robert A. Screaton, Fraser W. Scott and Rashmi Kothary

    Article first published online : 27 AUG 2012, DOI: 10.1002/ana.23582

  3. You have full text access to this OnlineOpen article
    Identification and characterization of the porcine (Sus scrofa) survival motor neuron (SMN1) gene: An animal model for therapeutic studies

    Developmental Dynamics

    Volume 237, Issue 8, August 2008, Pages: 2268–2278, Monique A. Lorson, Lee D. Spate, Randall S. Prather and Christian L. Lorson

    Article first published online : 23 JUL 2008, DOI: 10.1002/dvdy.21642

  4. You have full text access to this OnlineOpen article
    Smn deficiency causes neuritogenesis and neurogenesis defects in the retinal neurons of a mouse model of spinal muscular atrophy

    Developmental Neurobiology

    Volume 71, Issue 2, February 2011, Pages: 153–169, Hong Liu, Ariane Beauvais, Adam N. Baker, Catherine Tsilfidis and Rashmi Kothary

    Article first published online : 7 JAN 2011, DOI: 10.1002/dneu.20840

  5. Spinal muscular atrophy: Recent advances and future prospects

    Muscle & Nerve

    Volume 26, Issue 1, July 2002, Pages: 4–13, Sophie Nicole, Carmen Cifuentes Diaz, Tony Frugier and Judith Melki

    Article first published online : 15 APR 2002, DOI: 10.1002/mus.10110

  6. Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells

    Annals of Neurology

    Volume 58, Issue 2, August 2005, Pages: 194–202, Susanna M. Grzeschik, Madhuri Ganta, Thomas W. Prior, William D. Heavlin and Ching H. Wang

    Article first published online : 14 APR 2010, DOI: 10.1002/ana.20548

  7. You have full text access to this OnlineOpen article
    In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy

    Journal of Neurochemistry

    Volume 98, Issue 1, July 2006, Pages: 193–202, Eric Hahnen, Ilker Y. Eyüpoglu, Lars Brichta, Kirsten Haastert, Christian Tränkle, Florian A. Siebzehnrübl, Markus Riessland, Irmgard Hölker, Peter Claus, Johann Romstöck, Rolf Buslei, Brunhilde Wirth and Ingmar Blümcke

    Article first published online : 18 MAY 2006, DOI: 10.1111/j.1471-4159.2006.03868.x

  8. Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice

    British Journal of Pharmacology

    Volume 166, Issue 3, June 2012, Pages: 1114–1126, Ya-Yun Hsu, Yuh-Jyh Jong, Hsin-Hung Tsai, Yu-Ting Tseng, Li-Mei An and Yi-Ching Lo

    Article first published online : 8 MAY 2012, DOI: 10.1111/j.1476-5381.2012.01829.x

  9. Neurodevelopmental abnormalities in neurosphere-derived neural stem cells from SMN-depleted mice

    Journal of Neuroscience Research

    Volume 86, Issue 13, October 2008, Pages: 2839–2847, Dina Shafey, Alex E. MacKenzie and Rashmi Kothary

    Article first published online : 2 JUN 2008, DOI: 10.1002/jnr.21743

  10. You have free access to this content
    Generation of a tamoxifen inducible SMN mouse for temporal SMN replacement

    genesis

    Volume 49, Issue 12, December 2011, Pages: 927–934, Thomas W. Bebee, Jordan T. Gladman and Dawn S. Chandler

    Article first published online : 24 AUG 2011, DOI: 10.1002/dvg.20764

  11. You have free access to this content
    The emerging role of epigenetic modifications and chromatin remodeling in spinal muscular atrophy

    Journal of Neurochemistry

    Volume 109, Issue 6, June 2009, Pages: 1557–1569, Sebastian Lunke and Assam El-Osta

    Article first published online : 4 APR 2009, DOI: 10.1111/j.1471-4159.2009.06084.x

  12. In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate

    Annals of Neurology

    Volume 59, Issue 6, June 2006, Pages: 970–975, Lars Brichta, Irmgard Holker, Karsten Haug, Thomas Klockgether and Brunhilde Wirth

    Article first published online : 10 APR 2006, DOI: 10.1002/ana.20836

  13. Invertebrate models of spinal muscular atrophy: Insights into mechanisms and potential therapeutics

    BioEssays

    Volume 33, Issue 12, December 2011, Pages: 956–965, Stuart J. Grice, James N. Sleigh, Ji-Long Liu and David B. Sattelle

    Article first published online : 18 OCT 2011, DOI: 10.1002/bies.201100082

  14. You have full text access to this OnlineOpen article
    SMN2 exon 7 splicing is inhibited by binding of hnRNP A1 to a common ESS motif that spans the 3′ splice site

    Human Mutation

    Volume 32, Issue 2, February 2011, Pages: 220–230, Thomas Koed Doktor, Lisbeth Dahl Schroeder, Anne Vested, Johan Palmfeldt, Henriette Skovgaard Andersen, Niels Gregersen and Brage Storstein Andresen

    Article first published online : 25 JAN 2011, DOI: 10.1002/humu.21419

  15. Valproic acid increases SMN levels in spinal muscular atrophy patient cells

    Annals of Neurology

    Volume 54, Issue 5, November 2003, Pages: 647–654, Charlotte J. Sumner, Thanh N. Huynh, Jennifer A. Markowitz, J. Stephen Perhac, Brenna Hill, Daniel D. Coovert, Kristie Schussler, Xiaocun Chen, Jill Jarecki, Arthur H. M. Burghes, J. Paul Taylor and Kenneth H. Fischbeck

    Article first published online : 22 OCT 2003, DOI: 10.1002/ana.10743

  16. Review: Neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy

    Neuropathology and Applied Neurobiology

    Volume 36, Issue 2, April 2010, Pages: 133–156, L. M. Murray, K. Talbot and T. H. Gillingwater

    Article first published online : 23 MAR 2010, DOI: 10.1111/j.1365-2990.2010.01061.x

  17. SMN (Survival Motor Neuron) Gene and Protein

    Standard Article

    Encyclopedia Of Molecular Medicine

    Christian L. Lorson and Elliot J. Androphy

    Published Online : 15 JAN 2002, DOI: 10.1002/0471203076.emm0152

  18. Multi-exon genotyping of SMN gene in spinal muscular atrophy by universal fluorescent PCR and capillary electrophoresis

    ELECTROPHORESIS

    Volume 31, Issue 14, July 2010, Pages: 2396–2404, Chun-Chi Wang, Jan-Gowth Chang, Yen-Ling Chen, Yuh-Jyh Jong and Shou-Mei Wu

    Article first published online : 16 JUN 2010, DOI: 10.1002/elps.201000124

  19. You have full text access to this OnlineOpen article
    Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure

    Annals of Human Genetics

    Volume 72, Issue 2, March 2008, Pages: 288–291, Gunadi, T. H. Sasongko, S. Yusoff, M. J. Lee, E. Nishioka, M. Matsuo and H. Nishio

    Article first published online : 5 FEB 2008, DOI: 10.1111/j.1469-1809.2007.00409.x

  20. SMN and Gemins: ‘We are family’ … or are we?

    BioEssays

    Volume 32, Issue 12, December 2010, Pages: 1077–1089, Ruben J. Cauchi

    Article first published online : 15 OCT 2010, DOI: 10.1002/bies.201000088