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There are 30343 results for: content related to: Initial testing of the CENP-E inhibitor GSK923295A by the pediatric preclinical testing program

  1. You have free access to this content
    Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition

    International Journal of Cancer

    Volume 132, Issue 3, 1 February 2013, Pages: E149–E157, Patrick A. Mayes, Yan Y. Degenhardt, Andrew Wood, Yana Toporovskya, Sharon J. Diskin, Elizabeth Haglund, Christopher Moy, Richard Wooster and John M. Maris

    Article first published online : 28 SEP 2012, DOI: 10.1002/ijc.27781

  2. You have full text access to this Open Access content
    Oncogenic role of kinesin proteins and targeting kinesin therapy

    Cancer Science

    Volume 104, Issue 6, June 2013, Pages: 651–656, Xinran Liu, Hao Gong and Kun Huang

    Article first published online : 4 APR 2013, DOI: 10.1111/cas.12138

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    The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR


    Volume 8, Issue 6, June 2007, Pages: 718–732, Nasha Nassoury, Daniel A. Blasiole, Angie Tebon Oler, Suzanne Benjannet, Josée Hamelin, Vivianne Poupon, Peter S. McPherson, Alan D. Attie, Annik Prat and Nabil G. Seidah

    Article first published online : 25 APR 2007, DOI: 10.1111/j.1600-0854.2007.00562.x

  4. Proprotein Convertases Subtilisin/Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶—枯草溶菌素/蛋白酶K,一种酶转变的护送蛋白:在肝脏与肝外的功能)

    Journal of Diabetes

    Volume 5, Issue 4, December 2013, Pages: 391–405, Majambu Mbikay, Janice Mayne and Michel Chrétien

    Article first published online : 8 JUL 2013, DOI: 10.1111/1753-0407.12064

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    PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities

    FEBS Letters

    Volume 584, Issue 4, February 19, 2010, Pages: 701–706, Majambu Mbikay, Francine Sirois, Janice Mayne, Gen-Sheng Wang, Andrew Chen, Thilina Dewpura, Annik Prat, Nabil G. Seidah, Michel Chretien and Fraser W. Scott

    Article first published online : 16 DEC 2009, DOI: 10.1016/j.febslet.2009.12.018

  6. You have full text access to this OnlineOpen article
    β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cells

    FEBS Journal

    Volume 282, Issue 14, July 2015, Pages: 2682–2696, Amanda E. Starr, Valérie Lemieux, Jenny Noad, Jasmine I. Moore, Thilina Dewpura, Angela Raymond, Michel Chrétien, Daniel Figeys and Janice Mayne

    Article first published online : 18 MAY 2015, DOI: 10.1111/febs.13309

  7. Positive correlation of plasma PCSK9 levels with HbA1c in patients with type 2 diabetes

    Diabetes/Metabolism Research and Reviews

    Sheng-Hua Yang, Sha Li, Yan Zhang, Rui-Xia Xu, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Chuan-Jue Cui, Jing Sun and Jian-Jun Li

    Article first published online : 28 OCT 2015, DOI: 10.1002/dmrr.2712

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    PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression


    Volume 50, Issue 1, July 2009, Pages: 17–24, Patrick Labonté, Syntia Begley, Carl Guévin, Marie-Claude Asselin, Nasha Nassoury, Gaétan Mayer, Annik Prat and Nabil G. Seidah

    Article first published online : 18 FEB 2009, DOI: 10.1002/hep.22911

  9. Chromosome misalignments induce spindle-positioning defects

    EMBO reports

    Mihoko A Tame, Jonne A Raaijmakers, Pavel Afanasyev and René H Medema

    Article first published online : 4 FEB 2016, DOI: 10.15252/embr.201541143

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    Proprotein convertase subtilisin/kexin type 9 potentially influences cholesterol uptake in macrophages and reverse cholesterol transport

    FEBS Letters

    Volume 587, Issue 9, May 02, 2013, Pages: 1271–1274, Li Shen, Hong-chun Peng, Shannon N. Nees, Shui-ping Zhao and Dan-yan Xu

    Article first published online : 24 FEB 2013, DOI: 10.1016/j.febslet.2013.02.027

  11. Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) concentrations: a systematic review and meta-analysis of clinical trials

    Diabetes, Obesity and Metabolism

    Volume 17, Issue 11, November 2015, Pages: 1042–1055, A. Sahebkar, L. E. Simental-Mendía, F. Guerrero-Romero, J. Golledge and G. F. Watts

    Article first published online : 14 SEP 2015, DOI: 10.1111/dom.12536

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    Polyadenylation of Escherichia coli transcripts plays an integral role in regulating intracellular levels of polynucleotide phosphorylase and RNase E

    Molecular Microbiology

    Volume 45, Issue 5, September 2002, Pages: 1315–1324, Bijoy K. Mohanty and Sidney R. Kushner

    Article first published online : 2 SEP 2002, DOI: 10.1046/j.1365-2958.2002.03097.x

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    Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes

    FEBS Letters

    Volume 582, Issue 6, March 19, 2008, Pages: 949–955, Cédric Langhi, Cédric Le May, Sanae Kourimate, Sandrine Caron, Bart Staels, Michel Krempf, Philippe Costet and Bertrand Cariou

    Article first published online : 25 FEB 2008, DOI: 10.1016/j.febslet.2008.02.038

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    Polysialic acids: potential in drug delivery

    FEBS Letters

    Volume 315, Issue 3, January 11, 1993, Pages: 271–276, G. Gregoriadis, B. McCormack, Z. Wang and R. Lifely

    Article first published online : 14 NOV 2001, DOI: 10.1016/0014-5793(93)81177-2

  15. Pharmacokinetics and pharmacodynamics of GSK961081, a novel inhaled muscarinic antagonist β2-agonist, and fluticasone propionate administered alone, concurrently and as a combination blend formulation in healthy volunteers

    Clinical Pharmacology in Drug Development

    Volume 3, Issue 4, July/August 2014, Pages: 305–313, Virginia Norris, Claire Ambery and Trevor Riley

    Article first published online : 20 FEB 2014, DOI: 10.1002/cpdd.105

  16. You have full text access to this OnlineOpen article
    Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

    FEBS Open Bio

    Volume 4, Issue 1, January 01, 2014, Pages: 755–762, Majambu Mbikay, Francine Sirois, Sonia Simoes, Janice Mayne and Michel Chrétien

    Article first published online : 2 SEP 2014, DOI: 10.1016/j.fob.2014.08.003

  17. MMP-2 inhibits PCSK9-induced degradation of the LDL receptor in Hepa1-c1c7 cells

    FEBS Letters

    Volume 589, Issue 4, February 13, 2015, Pages: 490–496, Xiang Wang, Evan Berry, Samuel Hernandez-Anzaldo, Difei Sun, Ayinuer Adijiang, Liang Li, Dawei Zhang and Carlos Fernandez-Patron

    Article first published online : 19 JAN 2015, DOI: 10.1016/j.febslet.2015.01.007

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    Poster Session 4: Steatohepatitis: Clinical and Therapeutic


    Volume 62, Issue S1, October 2015, Pages: 1252A–1305A,

    Article first published online : 7 OCT 2015, DOI: 10.1002/hep.28240

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    The role of kinesin family proteins in tumorigenesis and progression


    Volume 116, Issue 22, 15 November 2010, Pages: 5150–5160, Yue Yu and Yu-Mei Feng

    Article first published online : 3 NOV 2010, DOI: 10.1002/cncr.25461

  20. Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells

    Journal of Cellular Physiology

    Volume 224, Issue 1, July 2010, Pages: 273–281, Hong Lan, Ling Pang, Marsha M. Smith, Diane Levitan, Wei Ding, Li Liu, Lixin Shan, Vidhi V. Shah, Maureen Laverty, Gladys Arreaza, Qing Zhang, Nicholas J. Murgolo, Marco Hernandez, Jonathan R. Greene, Eric L. Gustafson, Marvin L. Bayne, Harry R. Davis and Joseph A. Hedrick

    Article first published online : 23 MAR 2010, DOI: 10.1002/jcp.22130