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There are 18940 results for: content related to: Initial testing of the MDM2 inhibitor RG7112 by the pediatric preclinical testing program

  1. Inhibition of MDM2 by RG7388 confers hypersensitivity to X-radiation in xenograft models of childhood sarcoma

    Pediatric Blood & Cancer

    Volume 62, Issue 8, August 2015, Pages: 1345–1352, Doris Phelps, Kathryn Bondra, Star Seum, Christopher Chronowski, Justin Leasure, Raushan T. Kurmasheva, Steven Middleton, Dian Wang, Xiaokui Mo and Peter J. Houghton

    Version of Record online : 1 APR 2015, DOI: 10.1002/pbc.25465

  2. You have free access to this content
    MDM2 antagonist clinical response association with a gene expression signature in acute myeloid leukaemia

    British Journal of Haematology

    Volume 171, Issue 3, November 2015, Pages: 432–435, Hua Zhong, Gong Chen, Lori Jukofsky, David Geho, Sung Won Han, Fabian Birzele, Sabine Bader, Lucia Himmelein, James Cai, Zayed Albertyn, Mark Rothe, Laurent Essioux, Helmut Burtscher, Steven A. Middleton, Ruediger Rueger, Lin-Chi Chen, Markus Dangl, Gwen Nichols and William E. Pierceall

    Version of Record online : 8 APR 2015, DOI: 10.1111/bjh.13411

  3. Medicinal Chemistry Strategies to Disrupt the p53–MDM2/MDMX Interaction

    Medicinal Research Reviews

    Volume 36, Issue 5, September 2016, Pages: 789–844, Agostinho Lemos, Mariana Leão, Joana Soares, Andreia Palmeira, Madalena Pinto, Lucília Saraiva and Maria Emília Sousa

    Version of Record online : 15 JUN 2016, DOI: 10.1002/med.21393

  4. Initial Testing (Stage 1) of MK-8242—A Novel MDM2 Inhibitor—by the Pediatric Preclinical Testing Program

    Pediatric Blood & Cancer

    Volume 63, Issue 10, October 2016, Pages: 1744–1752, Min H. Kang, C. Patrick Reynolds, E. Anders Kolb, Richard Gorlick, Hernan Carol, Richard Lock, Stephen T. Keir, John M. Maris, Jianwrong Wu, Dmitry Lyalin, Raushan T. Kurmasheva, Peter J. Houghton and Malcolm A. Smith

    Version of Record online : 30 MAY 2016, DOI: 10.1002/pbc.26064

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    Pharmacological reactivation of p53 as a strategy to treat cancer

    Journal of Internal Medicine

    Volume 277, Issue 2, February 2015, Pages: 248–259, J. Zawacka-Pankau and G. Selivanova

    Version of Record online : 26 JAN 2015, DOI: 10.1111/joim.12336

  6. Association of MDM2 T309G and p53 Arg72Pro polymorphisms and gastroesophageal reflux disease with survival in esophageal adenocarcinoma

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 9, September 2013, Pages: 1482–1488, Daniel J Renouf, Rihong Zhai, Bin Sun, Wei Xu, Winson Y Cheung, Rebecca S Heist, Matthew H Kulke, David Cescon, Kofi Asomaning, Ariella L Marshall, Su Li, David C Christiani and Geoffrey Liu

    Version of Record online : 22 AUG 2013, DOI: 10.1111/jgh.12286

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    Wild type p53 reactivation: From lab bench to clinic

    FEBS Letters

    Volume 588, Issue 16, August 19, 2014, Pages: 2628–2638, Galina Selivanova

    Version of Record online : 12 APR 2014, DOI: 10.1016/j.febslet.2014.03.049

  8. Small molecule agents targeting the p53-MDM2 pathway for cancer therapy

    Medicinal Research Reviews

    Volume 32, Issue 6, November 2012, Pages: 1159–1196, Weisi Wang and Yongzhou Hu

    Version of Record online : 16 JAN 2011, DOI: 10.1002/med.20236

  9. Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein–Protein Interaction by a Scaffold-Hopping Approach

    Chemical Biology & Drug Design

    Volume 86, Issue 2, August 2015, Pages: 180–189, Andrey Zaytsev, Barry Dodd, Matteo Magnani, Chiara Ghiron, Bernard T. Golding, Roger J. Griffin, Junfeng Liu, Xiaohong Lu, Iolanda Micco, David R. Newell, Alessandro Padova, Graeme Robertson, John Lunec and Ian R. Hardcastle

    Version of Record online : 19 DEC 2014, DOI: 10.1111/cbdd.12474

  10. Poster Walk I

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue S1, February 2015, Pages: S57–S59,

    Version of Record online : 22 JAN 2015, DOI: 10.1002/cpt.51

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    Mapping and Characterization of a Sequential Epitope on the Rabies Virus Glycoprotein Which Is Recognized by a Neutralizing Monoclonal Antibody, RG719

    Microbiology and Immunology

    Volume 39, Issue 9, September 1995, Pages: 693–702, Yajin Ni, Yuichi Tominaga, Yoshikazu Honda, Kinjiro Morimoto, Shin'ichi Sakamoto and Akihiko Kawai

    Version of Record online : 14 NOV 2013, DOI: 10.1111/j.1348-0421.1995.tb03258.x

  12. Targeted therapy in sarcomas other than GIST tumors

    Journal of Surgical Oncology

    Volume 111, Issue 5, April 1, 2015, Pages: 632–640, Douglas Sborov and James L. Chen

    Version of Record online : 20 OCT 2014, DOI: 10.1002/jso.23802

  13. How To Design a Successful p53–MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures

    ChemMedChem

    Volume 11, Issue 8, April 19, 2016, Pages: 757–772, Natalia Estrada-Ortiz, Dr. Constantinos G. Neochoritis and Prof. Alexander Dömling

    Version of Record online : 16 DEC 2015, DOI: 10.1002/cmdc.201500487

  14. Discovery and Development of PSI-6130/RG7128

    Antiviral Drugs: From Basic Discovery through Clinical Trials

    Phillip A. Furman, Michael J. Otto, Michael J. Sofia, Pages: 305–315, 2011

    Published Online : 20 JUN 2011, DOI: 10.1002/9780470929353.ch21

  15. Poster Session II

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue S1, February 2015, Pages: S60–S96,

    Version of Record online : 22 JAN 2015, DOI: 10.1002/cpt.52

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    “Atypical femoral fractures” during bisphosphonate exposure in adult hypophosphatasia

    Journal of Bone and Mineral Research

    Volume 27, Issue 5, May 2012, Pages: 987–994, Roger AL Sutton, Steven Mumm, Stephen P Coburn, Karen L Ericson and Michael P Whyte

    Version of Record online : 18 APR 2012, DOI: 10.1002/jbmr.1565

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    The hepatitis B x antigen anti-apoptotic effector URG7 is localized to the endoplasmic reticulum membrane

    FEBS Letters

    Volume 587, Issue 18, September 17, 2013, Pages: 3058–3062, A. Ostuni, P. Lara, M.F. Armentano, R. Miglionico, A.M. Salvia, M. Mönnich, M. Carmosino, F.M. Lasorsa, M. Monné, I. Nilsson and F. Bisaccia

    Version of Record online : 31 JUL 2013, DOI: 10.1016/j.febslet.2013.07.042

  18. You have full text access to this OnlineOpen article
    Analysis of “On/Off” Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 4, Issue 8, August 2015, Pages: 465–473, J Lu, Y Cleary, C Maugeais, CI Kiu Weber and NA Mazer

    Version of Record online : 20 APR 2015, DOI: 10.1002/psp4.27

  19. SIOP 2015 Scientific Programme + Index

    Pediatric Blood & Cancer

    Volume 62, Issue S4, November 2015, Pages: S143–S418,

    Version of Record online : 9 SEP 2015, DOI: 10.1002/pbc.25715

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    Melanoma 2010 Congress

    Pigment Cell & Melanoma Research

    Volume 23, Issue 6, December 2010, Pages: 874–1004,

    Version of Record online : 13 OCT 2010, DOI: 10.1111/j.1755-148X.2010.00767.x