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There are 29422 results for: content related to: Exposure to CYP3A4-inducing and CYP3A4-non-inducing antiepileptic agents and the risk of fractures

  1. You have free access to this content
    Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes

    European Journal of Biochemistry

    Volume 268, Issue 24, December 2001, Pages: 6346–6358, Jean-Marc Pascussi, Lionel Drocourt, Sabine Gerbal-Chaloin, Jean-Michel Fabre, Patrick Maurel and Marie-José Vilarem

    Version of Record online : 12 JAN 2002, DOI: 10.1046/j.0014-2956.2001.02540.x

  2. In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone

    Clinical Pharmacology & Therapeutics

    Volume 68, Issue 4, October 2000, Pages: 356–366, Jeannine S. McCune, Roy L. Hawke, Edward L. LeCluyse, Heidi H. Gillenwater, Geraldine Hamilton, James Ritchie and Celeste Lindley

    Version of Record online : 29 OCT 2000, DOI: 10.1067/mcp.2000.110215

  3. Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors

    Clinical Pharmacology & Therapeutics

    Volume 66, Issue 6, December 1999, Pages: 589–593, Kirsti Villikka, Kari T. Kivistö, Hanna Mäenpää, Heikki Joensuu and Pertti J. Neuvonen

    Version of Record online : 19 DEC 1999, DOI: 10.1053/cp.1999.v66.103403001

  4. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies

    Journal of Pharmaceutical Sciences

    Volume 90, Issue 11, November 2001, Pages: 1736–1751, Helena A. Engman, Hans Lennernäs, Jan Taipalensuu, Charlotta Otter, Brith Leidvik and Per Artursson

    Version of Record online : 22 OCT 2001, DOI: 10.1002/jps.1123

  5. An integrated pharmacokinetic model for the influence of CYP3A4 expression on the in vivo disposition of lopinavir and its modulation by ritonavir

    Journal of Pharmaceutical Sciences

    Volume 100, Issue 6, June 2011, Pages: 2508–2515, Rob ter Heine, Robert A. B. Van Waterschoot, Ron J. Keizer, Jos H. Beijnen, Alfred H. Schinkel and Alwin D. R. Huitema

    Version of Record online : 29 DEC 2010, DOI: 10.1002/jps.22457

  6. A pilot evaluation of alfentanil-induced miosis as a noninvasive probe for hepatic cytochrome P450 3A4 (CYP3A4) activity in humans

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 6, December 2001, Pages: 505–517, Somphane Phimmasone and Evan D. Kharasch

    Version of Record online : 16 DEC 2001, DOI: 10.1016/S0009-9236(01)23711-4

  7. Flavonoids and polymer derivatives as CYP3A4 inhibitors for improved oral drug bioavailability

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 2, February 2013, Pages: 541–555, Pius Fasinu, Yahya E. Choonara, Riaz A. Khan, Lisa C. Du Toit, Pradeep Kumar, Valence M. K. Ndesendo and Viness Pillay

    Version of Record online : 27 NOV 2012, DOI: 10.1002/jps.23382

  8. You have free access to this content
    Dose-dependent Induction of Cytochrome P450 (CYP) 3A4 and Activation of Pregnane X Receptor by Topiramate


    Volume 44, Issue 12, December 2003, Pages: 1521–1528, Srikanth C. Nallani, Tracy A. Glauser, Niresh Hariparsad, Kenneth Setchell, Donna J. Buckley, Arthur R. Buckley and Pankaj B. Desai

    Version of Record online : 25 NOV 2003, DOI: 10.1111/j.0013-9580.2003.06203.x

  9. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype

    Clinical Pharmacology & Therapeutics

    Volume 79, Issue 4, April 2006, Pages: 325–338, Jatinder Lamba, Stephen Strom, Raman Venkataramanan, Kenneth E. Thummel, Yvonne S. Lin, Wei Liu, Cheng Cheng, Vishal Lamba, Paul B. Watkins and Erin Schuetz

    Version of Record online : 16 APR 2006, DOI: 10.1016/j.clpt.2005.11.013

  10. In Silico Predictions of Drug – Drug Interactions Caused by CYP1A2, 2C9 and 3A4 Inhibition – a Comparative Study of Virtual Screening Performance

    Molecular Informatics

    Volume 34, Issue 6-7, June 2015, Pages: 431–457, Teresa Kaserer, Martina Höferl, Klara Müller, Sebastian Elmer, Markus Ganzera, Walter Jäger and Daniela Schuster

    Version of Record online : 23 JUN 2015, DOI: 10.1002/minf.201400192

  11. You have free access to this content
    Poster Session Monday July 3, 2006 13:30–15:00 Poster Session 1 Adult Epileptology


    Volume 47, Issue s3, December 2006, Pages: 36–68,

    Version of Record online : 11 JAN 2007, DOI: 10.1111/j.1528-1167.2006.00715_22.x

  12. You have free access to this content
    Pregnane X receptor- and CYP3A4-humanized mouse models and their applications

    British Journal of Pharmacology

    Volume 163, Issue 3, June 2011, Pages: 461–468, Jie Cheng, Xiaochao Ma and Frank J Gonzalez

    Version of Record online : 11 MAY 2011, DOI: 10.1111/j.1476-5381.2010.01129.x

  13. Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population

    Pharmacoepidemiology and Drug Safety

    Volume 21, Issue 5, May 2012, Pages: 485–493, Ameet Bakhai, Una Rigney, Samuel Hollis and Cathy Emmas

    Version of Record online : 12 JAN 2012, DOI: 10.1002/pds.2308

  14. Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the anti-tumour imidazoacridinone C-1311 in human hepatoma cells

    Cell Biology International

    Volume 37, Issue 2, February 2013, Pages: 109–120, Ewa Augustin, Monika Pawłowska, Joanna Polewska, Agnieszka Potega and Zofia Mazerska

    Version of Record online : 14 JAN 2013, DOI: 10.1002/cbin.10018

  15. You have full text access to this OnlineOpen article
    Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 3, Issue 6, June 2014, Pages: 1–10, TA Leil, S Kasichayanula, DW Boulton and F LaCreta

    Version of Record online : 25 JUN 2014, DOI: 10.1038/psp.2014.18

  16. You have free access to this content
    Monday July 3, 2006 13:30–15:00 Poster Session 1 Genetics


    Volume 47, Issue s3, December 2006, Pages: 85–92,

    Version of Record online : 11 JAN 2007, DOI: 10.1111/j.1528-1167.2006.00715_25.x

  17. Enzyme- and Transporter-Mediated Drug Interactions with Small Molecule Tyrosine Kinase Inhibitors

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 12, December 2014, Pages: 3810–3833, Jie Shao, John S. Markowitz, Di Bei and Guohua An

    Version of Record online : 10 OCT 2014, DOI: 10.1002/jps.24113

  18. You have free access to this content
    Wednesday July 5, 2006 9:30–11:30 Hall 1 Main Session New concepts in pharmacotherapy


    Volume 47, Issue s3, December 2006, Pages: 251–253,

    Version of Record online : 11 JAN 2007, DOI: 10.1111/j.1528-1167.2006.00715_71.x

  19. Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies

    Fundamental & Clinical Pharmacology

    Volume 14, Issue 4, July-August 2000, Pages: 301–319, Margherita Strolin Benedetti

    Version of Record online : 26 AUG 2009, DOI: 10.1111/j.1472-8206.2000.tb00411.x

  20. PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 91, Issue 6, June 2012, Pages: 1044–1052, Kathrin Klein, Maria Thomas, Stefan Winter, Andreas K. Nussler, Mikko Niemi, Matthias Schwab and Ulrich M. Zanger

    Version of Record online : 18 APR 2012, DOI: 10.1038/clpt.2011.336