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There are 54526 results for: content related to: Benefit-risk analysis: examples using quantitative methods

  1. Approach to the determination of hydrate form conversions of drug compounds and solid dosage forms by near-infrared spectroscopy

    Journal of Pharmaceutical Sciences

    Volume 92, Issue 11, November 2003, Pages: 2303–2316, John P. Higgins, Steven M. Arrivo and Robert A. Reed

    Version of Record online : 25 AUG 2003, DOI: 10.1002/jps.10465

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    The cross-over trial: a subtle knife


    Volume 5, Issue 3, September 2008, Pages: 135–137, Byron Jones

    Version of Record online : 28 AUG 2008, DOI: 10.1111/j.1740-9713.2008.00312.x

  3. Considerations for Clinical Trial Design and Data Analyses of Thorough QT Studies Using Drug-Drug Interaction

    The Journal of Clinical Pharmacology

    Volume 50, Issue 10, October 2010, Pages: 1106–1111, Hao Zhu, Yaning Wang, Jogarao V. Gobburu and Christine E. Garnett

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009358710

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    Advanced Statistics: How to Determine Whether Your Intervention Is Different, At Least As Effective As, or Equivalent: A Basic Introduction

    Academic Emergency Medicine

    Volume 12, Issue 6, June 2005, Pages: 536–542, Joshua H. Tamayo-Sarver, Jeffrey M. Albert, Maritza Tamayo-Sarver and Rita K. Cydulka

    Version of Record online : 28 JUN 2008, DOI: 10.1197/j.aem.2005.01.010

  5. Drug Combinations: Tests and Analysis with Isoboles


    Current Protocols in Pharmacology


    Ronald J. Tallarida

    Published Online : 18 MAR 2016, DOI: 10.1002/0471141755.ph0919s72

  6. A mixed effects model for the analysis of ordinal longitudinal pain data subject to informative drop-out

    Statistics in Medicine

    Volume 20, Issue 4, 28 February 2001, Pages: 601–622, Erik Pulkstenis, Thomas R. Ten Have and J. Richard Landis

    Version of Record online : 5 FEB 2001, DOI: 10.1002/sim.696

  7. An efficient design for a study comparing two drugs, their combination and placebo

    Statistics in Medicine

    Volume 25, Issue 12, 30 June 2006, Pages: 2043–2058, Lynn Wei

    Version of Record online : 11 OCT 2005, DOI: 10.1002/sim.2336

  8. A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data

    Statistics in Medicine

    Volume 34, Issue 13, 15 June 2015, Pages: 2138–2164, Amy Cotterill, Daniel Lorand, Jixian Wang and Thomas Jaki

    Version of Record online : 24 MAR 2015, DOI: 10.1002/sim.6482

  9. Count Data in Tables

    The R Book, Second Edition

    Michael J. Crawley, Pages: 599–627, 2012

    Published Online : 6 NOV 2012, DOI: 10.1002/9781118448908.ch15

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    Bioavailability of four ursodeoxycholic acid preparations

    Alimentary Pharmacology & Therapeutics

    Volume 14, Issue 9, September 2000, Pages: 1133–1139, Williams, Al-Knawy and Blanchard

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2036.2000.00817.x

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    A product of independent beta probabilities dose escalation design for dual-agent phase I trials

    Statistics in Medicine

    Volume 34, Issue 8, 15 April 2015, Pages: 1261–1276, Adrian P. Mander and Michael J. Sweeting

    Version of Record online : 29 JAN 2015, DOI: 10.1002/sim.6434

  12. Pharmacologic Advances in the Global Control and Treatment of Malaria: Combination Therapy and Resistance

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 5, November 2007, Pages: 601–605, M M Nyunt and C V Plowe

    Version of Record online : 26 SEP 2007, DOI: 10.1038/sj.clpt.6100361

  13. The Stroke Therapy Research Boom: Implications for the Hospital Formulary

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 18, Issue 3P2, May-June 1998, Pages: 108S–115S, N. Kathryn Bender

    Version of Record online : 17 JAN 2012, DOI: 10.1002/j.1875-9114.1998.tb03888.x

  14. Associations: Chance, Confounded or Causal?

    Interpretation and Uses of Medical Statistics, Fifth Edition

    Leslie E. Daly, Geoffrey J. Bourke, Pages: 57–85, 2008

    Published Online : 16 APR 2008, DOI: 10.1002/9780470696750.ch3

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    Analysis of drug combinations: current methodological landscape

    Pharmacology Research & Perspectives

    Volume 3, Issue 3, June 2015, Julie Foucquier and Mickael Guedj

    Version of Record online : 20 MAY 2015, DOI: 10.1002/prp2.149

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    Quantification of the Forgiveness of Drugs to Imperfect Adherence

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 4, Issue 3, March 2015, Pages: 204–211, P Assawasuwannakit, R Braund and SB Duffull

    Version of Record online : 4 MAR 2015, DOI: 10.1002/psp4.4

  17. Sequential continual reassessment method for two-dimensional dose finding

    Statistics in Medicine

    Volume 27, Issue 27, 29 November 2008, Pages: 5664–5678, Ying Yuan and Guosheng Yin

    Version of Record online : 11 JUL 2008, DOI: 10.1002/sim.3372

  18. Clinical Pharmacology of Topiramate versus Lamotrigine versus Phenobarbital: Comparison of Efficacy and Side Effects Using Odds Ratios

    The Journal of Clinical Pharmacology

    Volume 43, Issue 5, May 2003, Pages: 491–503, Claire M. Lathers, Paul L. Schraeder and H. Gregg Claycamp

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270003251837

  19. Pharmacodynamics

    Preclinical Development Handbook: ADME and Biopharmaceutical Properties

    Beom Soo Shin, Dhaval Shah, Joseph P. Balthasar, Pages: 1133–1166, 2007

    Published Online : 27 AUG 2007, DOI: 10.1002/9780470249031.ch34

  20. Presenting results of probabilistic sensitivity analysis: the incremental benefit curve

    Health Economics

    Volume 17, Issue 3, March 2008, Pages: 435–440, Mohan V. Bala, Gary A. Zarkin and Josephine Mauskopf

    Version of Record online : 13 AUG 2007, DOI: 10.1002/hec.1274