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There are 15233 results for: content related to: Benefit-risk analysis: examples using quantitative methods

  1. Approach to the determination of hydrate form conversions of drug compounds and solid dosage forms by near-infrared spectroscopy

    Journal of Pharmaceutical Sciences

    Volume 92, Issue 11, November 2003, Pages: 2303–2316, John P. Higgins, Steven M. Arrivo and Robert A. Reed

    Article first published online : 25 AUG 2003, DOI: 10.1002/jps.10465

  2. A mixed effects model for the analysis of ordinal longitudinal pain data subject to informative drop-out

    Statistics in Medicine

    Volume 20, Issue 4, 28 February 2001, Pages: 601–622, Erik Pulkstenis, Thomas R. Ten Have and J. Richard Landis

    Article first published online : 5 FEB 2001, DOI: 10.1002/sim.696

  3. Abstracts

    Pharmacoepidemiology and Drug Safety

    Volume 23, Issue S1, October 2014, Pages: 1–497,

    Article first published online : 30 SEP 2014, DOI: 10.1002/pds.3701

  4. Count Data in Tables

    The R Book, Second Edition

    Michael J. Crawley, Pages: 599–627, 2012

    Published Online : 6 NOV 2012, DOI: 10.1002/9781118448908.ch15

  5. You have free access to this content
    Bioavailability of four ursodeoxycholic acid preparations

    Alimentary Pharmacology & Therapeutics

    Volume 14, Issue 9, September 2000, Pages: 1133–1139, Williams, Al-Knawy and Blanchard

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1365-2036.2000.00817.x

  6. Pharmacologic Advances in the Global Control and Treatment of Malaria: Combination Therapy and Resistance

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 5, November 2007, Pages: 601–605, M M Nyunt and C V Plowe

    Article first published online : 26 SEP 2007, DOI: 10.1038/sj.clpt.6100361

  7. Considerations for Clinical Trial Design and Data Analyses of Thorough QT Studies Using Drug-Drug Interaction

    The Journal of Clinical Pharmacology

    Volume 50, Issue 10, October 2010, Pages: 1106–1111, Hao Zhu, Yaning Wang, Jogarao V. Gobburu and Christine E. Garnett

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270009358710

  8. Abstracts

    Pharmacoepidemiology and Drug Safety

    Volume 20, Issue S1, August 2011, Pages: S1–S364,

    Article first published online : 12 AUG 2011, DOI: 10.1002/pds.2206

  9. You have free access to this content
    Advanced Statistics: How to Determine Whether Your Intervention Is Different, At Least As Effective As, or Equivalent: A Basic Introduction

    Academic Emergency Medicine

    Volume 12, Issue 6, June 2005, Pages: 536–542, Joshua H. Tamayo-Sarver, Jeffrey M. Albert, Maritza Tamayo-Sarver and Rita K. Cydulka

    Article first published online : 28 JUN 2008, DOI: 10.1197/j.aem.2005.01.010

  10. UHPLC-MS/MS quantification of buprenorphine, norbuprenorphine, methadone, and glucuronide conjugates in umbilical cord plasma

    Biomedical Chromatography

    Amy Redmond Kyle, Jennifer Carmical, Darshan Shah, Jason Pryor and Stacy Brown

    Article first published online : 22 MAR 2015, DOI: 10.1002/bmc.3460

  11. The Stroke Therapy Research Boom: Implications for the Hospital Formulary

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 18, Issue 3P2, May-June 1998, Pages: 108S–115S, N. Kathryn Bender

    Article first published online : 17 JAN 2012, DOI: 10.1002/j.1875-9114.1998.tb03888.x

  12. Clinical Pharmacology of Topiramate versus Lamotrigine versus Phenobarbital: Comparison of Efficacy and Side Effects Using Odds Ratios

    The Journal of Clinical Pharmacology

    Volume 43, Issue 5, May 2003, Pages: 491–503, Claire M. Lathers, Paul L. Schraeder and H. Gregg Claycamp

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270003251837

  13. Balancing benefit and risk of medicines: a systematic review and classification of available methodologies

    Pharmacoepidemiology and Drug Safety

    Volume 23, Issue 7, July 2014, Pages: 667–678, Shahrul Mt-Isa, Christine E. Hallgreen, Nan Wang, Torbjörn Callréus, Georgy Genov, Ian Hirsch, Stephen F. Hobbiger, Kimberley S. Hockley, Davide Luciani, Lawrence D. Phillips, George Quartey, Sinan B. Sarac, Isabelle Stoeckert, Ioanna Tzoulaki, Alain Micaleff, Deborah Ashby and On behalf of the IMI-PROTECT benefit–risk participants

    Article first published online : 13 MAY 2014, DOI: 10.1002/pds.3636

  14. Test non-inferiority (and equivalence) based on the odds ratio under a simple crossover trial

    Statistics in Medicine

    Volume 30, Issue 11, 20 May 2011, Pages: 1230–1242, Kung-Jong Lui and Kuang-Chao Chang

    Article first published online : 12 JAN 2011, DOI: 10.1002/sim.4166

  15. Matrix effects during analysis of plasma samples by electrospray and atmospheric pressure chemical ionization mass spectrometry: practical approaches to their elimination

    Rapid Communications in Mass Spectrometry

    Volume 17, Issue 17, 15 September 2003, Pages: 1950–1957, Joachim Schuhmacher, Dieter Zimmer, Frank Tesche and Volker Pickard

    Article first published online : 18 JUL 2003, DOI: 10.1002/rcm.1139

  16. The application of large gaussian mixed models to the analysis of 24 hour ambulatory blood pressure monitoring data in clinical trials

    Statistics in Medicine

    Volume 12, Issue 18, 30 September 1993, Pages: 1665–1682, Murray R. Selwyn and Donna M. Difranco

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780121803

  17. Practical pharmacovigilance analysis strategies

    Pharmacoepidemiology and Drug Safety

    Volume 12, Issue 7, October/November 2003, Pages: 559–574, A. Lawrence Gould

    Article first published online : 1 NOV 2002, DOI: 10.1002/pds.771

  18. An efficient design for a study comparing two drugs, their combination and placebo

    Statistics in Medicine

    Volume 25, Issue 12, 30 June 2006, Pages: 2043–2058, Lynn Wei

    Article first published online : 11 OCT 2005, DOI: 10.1002/sim.2336

  19. A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data

    Statistics in Medicine

    Volume 34, Issue 13, 15 June 2015, Pages: 2138–2164, Amy Cotterill, Daniel Lorand, Jixian Wang and Thomas Jaki

    Article first published online : 24 MAR 2015, DOI: 10.1002/sim.6482

  20. You have free access to this content
    A Review of Quantitative Risk–Benefit Methodologies for Assessing Drug Safety and Efficacy—Report of the ISPOR Risk–Benefit Management Working Group

    Value in Health

    Volume 13, Issue 5, August 2010, Pages: 657–666, Jeff J. Guo, Swapnil Pandey, John Doyle, Boyang Bian, Yvonne Lis and Dennis W. Raisch

    Article first published online : 15 APR 2010, DOI: 10.1111/j.1524-4733.2010.00725.x