Search Results

There are 7839484 results for: content related to: Biomarkers in pediatrics: Children as biomarker orphans

  1. A statistician's perspective on biomarkers in drug development

    Pharmaceutical Statistics

    Volume 10, Issue 6, November/December 2011, Pages: 494–507, Martin Jenkins, Aiden Flynn, Trevor Smart, Chris Harbron, Tony Sabin, Jayantha Ratnayake, Paul Delmar, Athula Herath, Philip Jarvis, James Matcham and on behalf of the PSI Biomarker Special Interest Group

    Version of Record online : 8 DEC 2011, DOI: 10.1002/pst.532

  2. On comparing heterogeneity across biomarkers

    Cytometry Part A

    Volume 87, Issue 6, June 2015, Pages: 558–567, Robert J. Steininger III, Satwik Rajaram, Luc Girard, John D. Minna, Lani F. Wu and Steven J. Altschuler

    Version of Record online : 25 NOV 2014, DOI: 10.1002/cyto.a.22599

  3. Opportunities and Challenges of Safety Biomarker Qualification: Perspectives from the Predictive Safety Testing Consortium

    Drug Development Research

    Volume 74, Issue 2, March 2013, Pages: 112–126, Eslie H. Dennis, Elizabeth G. Walker, Amanda F. Baker and Richard T. Miller

    Version of Record online : 22 FEB 2013, DOI: 10.1002/ddr.21070

  4. Clinical Validation and Biomarker Translation

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    David Lin, Andreas Scherer, Raymond Ng, Robert Balshaw, Shawna Flynn, Paul Keown, Robert McMaster and Bruce McManus

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse270

  5. Multiple testing of treatment-effect-modifying biomarkers in a randomized clinical trial with a survival endpoint

    Statistics in Medicine

    Volume 30, Issue 13, 15 June 2011, Pages: 1502–1518, Stefan Michiels, Richard F. Potthoff and Stephen L. George

    Version of Record online : 23 FEB 2011, DOI: 10.1002/sim.4022

  6. Biomarker Qualification: Toward a Multiple Stakeholder Framework for Biomarker Development, Regulatory Acceptance, and Utilization

    Clinical Pharmacology & Therapeutics

    Volume 98, Issue 1, July 2015, Pages: 34–46, S Amur, L LaVange, I Zineh, S Buckman-Garner and J Woodcock

    Version of Record online : 6 JUN 2015, DOI: 10.1002/cpt.136

  7. Blood biomarkers for the non-invasive diagnosis of endometriosis

    Diagnostic Test Accuracy Review

    The Cochrane Library

    Vicki Nisenblat, Patrick MM Bossuyt, Rabia Shaikh, Cindy Farquhar, Vanessa Jordan, Carola S Scheffers, Ben Willem J Mol, Neil Johnson and M Louise Hull

    Published Online : 1 MAY 2016, DOI: 10.1002/14651858.CD012179

  8. You have free access to this content
    Better cancer biomarker discovery through better study design

    European Journal of Clinical Investigation

    Volume 42, Issue 12, December 2012, Pages: 1350–1359, Andrew Rundle, Habibul Ahsan and Paolo Vineis

    Version of Record online : 23 SEP 2012, DOI: 10.1111/j.1365-2362.2012.02727.x

  9. Early Diagnosis of Complex Diseases by Molecular Biomarkers, Network Biomarkers, and Dynamical Network Biomarkers

    Medicinal Research Reviews

    Volume 34, Issue 3, May 2014, Pages: 455–478, Rui Liu, Xiangdong Wang, Kazuyuki Aihara and Luonan Chen

    Version of Record online : 17 JUN 2013, DOI: 10.1002/med.21293

  10. Imaging as a Localized Biomarker: Opportunities and Challenges

    Standard Article

    Pharmaceutical Sciences Encyclopedia

    Jonathan B. Moody, Philip S. Murphy and Edward P. Ficaro

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse255

  11. You have free access to this content
    Biomarkers: refining diagnosis and expediting drug development – reality, aspiration and the role of open innovation

    Journal of Internal Medicine

    Volume 276, Issue 3, September 2014, Pages: 215–228, H. Salter and R. Holland

    Version of Record online : 28 MAR 2014, DOI: 10.1111/joim.12234

  12. Validity of biomarkers predicting onset or progression of nephropathy in patients with Type 2 diabetes: a systematic review

    Diabetic Medicine

    Volume 29, Issue 5, May 2012, Pages: 567–577, M. E. Hellemons, J. Kerschbaum, S. J. L. Bakker, H. Neuwirt, B. Mayer, G. Mayer, D. de Zeeuw, H. J. Lambers Heerspink and M. Rudnicki

    Version of Record online : 16 APR 2012, DOI: 10.1111/j.1464-5491.2011.03437.x

  13. Future Prospects for Biomarkers of Alcohol Consumption and Alcohol-Induced Disorders

    Alcoholism: Clinical and Experimental Research

    Volume 34, Issue 6, June 2010, Pages: 946–954, Willard M. Freeman and Kent E. Vrana

    Version of Record online : 5 APR 2010, DOI: 10.1111/j.1530-0277.2010.01169.x

  14. You have free access to this content
    DEVELOPING BIOMARKERS IN MOOD DISORDERS RESEARCH THROUGH THE USE OF RAPID-ACTING ANTIDEPRESSANTS

    Depression and Anxiety

    Volume 31, Issue 4, April 2014, Pages: 297–307, Mark J. Niciu, Daniel C. Mathews, Allison C. Nugent, Dawn F. Ionescu, Maura L. Furey, Erica M. Richards, Rodrigo Machado-Vieira and Carlos A. Zarate Jr.

    Version of Record online : 18 DEC 2013, DOI: 10.1002/da.22224

  15. You have full text access to this OnlineOpen article
    Antibody-based proteomics and biomarker research—Current status and limitations

    PROTEOMICS

    Volume 14, Issue 6, March 2014, Pages: 774–783, Corinne Solier and Hanno Langen

    Version of Record online : 6 MAR 2014, DOI: 10.1002/pmic.201300334

  16. The Challenge of Mild Traumatic Brain Injury: Role of Biochemical Markers in Diagnosis of Brain Damage

    Medicinal Research Reviews

    Volume 34, Issue 3, May 2014, Pages: 503–531, Stefania Mondello, Kara Schmid, Rachel P. Berger, Firas Kobeissy, Domenico Italiano, Andreas Jeromin, Ronal L. Hayes, Frank C. Tortella and Andras Buki

    Version of Record online : 28 JUN 2013, DOI: 10.1002/med.21295

  17. The Role of Biomarkers in Drug Discovery and Development: Enabling PK/PD

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Gabriella Szekely-Klepser and Erick Kindt

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm111

  18. Identification of drug-induced toxicity biomarkers for treatment determination

    Pharmaceutical Statistics

    Volume 14, Issue 4, July/August 2015, Pages: 284–293, Tzu-Pin Lu and James J. Chen

    Version of Record online : 27 APR 2015, DOI: 10.1002/pst.1684

  19. Semiparametric transformation models for multiple continuous biomarkers in ROC analysis

    Biometrical Journal

    Volume 57, Issue 5, September 2015, Pages: 808–833, Eunhee Kim, Donglin Zeng and Xiao-Hua Zhou

    Version of Record online : 3 JUL 2015, DOI: 10.1002/bimj.201400043

  20. Advances in membrane proteomics and cancer biomarker discovery: Current status and future perspective

    PROTEOMICS

    Volume 12, Issue 19-20, October 2012, Pages: 3085–3104, Hem D. Shukla, Paulius Vaitiekunas and Robert J. Cotter

    Version of Record online : 19 SEP 2012, DOI: 10.1002/pmic.201100519