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There are 6545 results for: content related to: Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721

  1. You have free access to this content
    Pregnane X receptor- and CYP3A4-humanized mouse models and their applications

    British Journal of Pharmacology

    Volume 163, Issue 3, June 2011, Pages: 461–468, Jie Cheng, Xiaochao Ma and Frank J Gonzalez

    Article first published online : 11 MAY 2011, DOI: 10.1111/j.1476-5381.2010.01129.x

  2. Nuclear Receptor-Mediated Gene Regulation in Drug Metabolism

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    Pharmaceutical Sciences Encyclopedia

    Hongbing Wang and wen xie

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470571224.pse116

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    Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis

    British Journal of Pharmacology

    Volume 151, Issue 3, June 2007, Pages: 367–376, S Teng and M Piquette-Miller

    Article first published online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0707235

  4. Motivated Behaviors and Levels of 3α,5α-THP in the Midbrain Are Attenuated by Knocking Down Expression of Pregnane Xenobiotic Receptor in the Midbrain Ventral Tegmental Area of Proestrous Rats

    The Journal of Sexual Medicine

    Volume 10, Issue 7, July 2013, Pages: 1692–1706, Cheryl Anne Frye, Carolyn J. Koonce, Alicia A. Walf and Jamie C. Rusconi

    Article first published online : 1 MAY 2013, DOI: 10.1111/jsm.12173

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    Pregnane X receptor is essential for normal progression of liver regeneration


    Volume 47, Issue 4, April 2008, Pages: 1277–1287, Guoli Dai, Lin He, Pengli Bu and Yu-Jui Yvonne Wan

    Article first published online : 31 DEC 2007, DOI: 10.1002/hep.22129

  6. Transcriptional Regulation of Cytochrome P450 Genes

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    Encyclopedia of Drug Metabolism and Interactions

    Emily A. Fraser, Colin J. Henderson and C. Roland Wolf

    Published Online : 31 JAN 2012, DOI: 10.1002/9780470921920.edm008

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    Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice


    Volume 41, Issue 3, March 2005, Pages: 497–505, Simrat P. S. Saini, Ying Mu, Haibiao Gong, David Toma, Hirdesh Uppal, Songrong Ren, Song Li, Samuel M. Poloyac and Wen Xie

    Article first published online : 22 FEB 2005, DOI: 10.1002/hep.20570

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    Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines


    Volume 109, Issue 5, 1 March 2007, Pages: 957–965, Edith J. Mensah-Osman, Dafydd G. Thomas, Michelle M. Tabb, Jose M. Larios, Dennis P. Hughes, Thomas J. Giordano, Michelle L. Lizyness, James M. Rae, Bruce Blumberg, Paul F. Hollenberg and Laurence H. Baker

    Article first published online : 5 FEB 2007, DOI: 10.1002/cncr.22479

    Corrected by:

    Erratum: Erratum

    Vol. 119, Issue 5, 1115, Article first published online: 12 OCT 2012

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    Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice


    Volume 56, Issue 2, August 2012, Pages: 658–667, Shujuan Chen, Mei-Fei Yueh, Ronald M. Evans and Robert H. Tukey

    Article first published online : 11 JUN 2012, DOI: 10.1002/hep.25671

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    Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease

    Inflammatory Bowel Diseases

    Volume 17, Issue 9, September 2011, Pages: 1917–1924, Jürgen Glas, Julia Seiderer, Daniel Fischer, Barbara Tengler, Simone Pfennig, Martin Wetzke, Florian Beigel, Torsten Olszak, Maria Weidinger, Burkhard Göke, Thomas Ochsenkühn, Matthias Folwaczny, Bertram Müller-Myhsok, Julia Diegelmann, Darina Czamara and Stephan Brand

    Article first published online : 3 DEC 2010, DOI: 10.1002/ibd.21562

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    A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte


    Volume 49, Issue 6, June 2009, Pages: 2068–2079, Amélie Moreau, Christelle Téruel, Michel Beylot, Valérie Albalea, Viola Tamasi, Thierry Umbdenstock, Yannick Parmentier, Antonio Sa-Cunha, Bertrand Suc, Jean-Michel Fabre, Francis Navarro, Jeanne Ramos, Urs Meyer, Patrick Maurel, Marie-José Vilarem and Jean-Marc Pascussi

    Article first published online : 11 FEB 2009, DOI: 10.1002/hep.22907

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    Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor

    British Journal of Pharmacology

    Volume 165, Issue 5, March 2012, Pages: 1595–1608, E Hoffart, L Ghebreghiorghis, AK Nussler, WE Thasler, TS Weiss, M Schwab and O Burk

    Article first published online : 10 FEB 2012, DOI: 10.1111/j.1476-5381.2011.01665.x

  13. Differential expression of the nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) for grading dysplasia in patients with Barrett’s oesophagus


    Volume 58, Issue 2, January 2011, Pages: 246–253, Anouk van de Winkel, Katinka P M van Zoest, Herman van Dekken, Leon M G Moons, Ernst J Kuipers and Luc J W van der Laan

    Article first published online : 16 FEB 2011, DOI: 10.1111/j.1365-2559.2011.03743.x

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    CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice


    Volume 42, Issue 2, August 2005, Pages: 420–430, Martin Wagner, Emina Halilbasic, Hanns-Ulrich Marschall, Gernot Zollner, Peter Fickert, Cord Langner, Kurt Zatloukal, Helmut Denk and Michael Trauner

    Article first published online : 28 JUN 2005, DOI: 10.1002/hep.20784

  15. Affinity purification using recombinant PXR as a tool to characterize environmental ligands

    Environmental Toxicology

    Volume 29, Issue 2, February 2014, Pages: 207–215, Sonia Dagnino, Virginie Bellet, Marina Grimaldi, Anne Riu, Sélim Aït-Aïssa, Vincent Cavaillès, Hélène Fenet and Patrick Balaguer

    Article first published online : 5 JAN 2012, DOI: 10.1002/tox.20787

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    Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes

    Journal of Thrombosis and Haemostasis

    Volume 8, Issue 12, December 2010, Pages: 2708–2717, A. RULCOVA, I. PROKOPOVA, L. KRAUSOVA, M. BITMAN, R. VRZAL, Z. DVORAK, J. BLAHOS and P. PAVEK

    Article first published online : 8 DEC 2010, DOI: 10.1111/j.1538-7836.2010.04036.x

  17. The Effect of In Vitro Dieldrin Exposure on the Rat Paraoxonase 1 (Pon1) Promoter

    Journal of Biochemical and Molecular Toxicology

    Volume 28, Issue 5, May 2014, Pages: 224–231, Mary Beth Dail, Rebecca Pickin, John Allen Crow and Janice E. Chambers

    Article first published online : 10 MAR 2014, DOI: 10.1002/jbt.21557

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    Inherent sex-dependent regulation of human hepatic CYP3A5

    British Journal of Pharmacology

    Volume 168, Issue 4, February 2013, Pages: 988–1000, Chellappagounder Thangavel, Ettickan Boopathi and Bernard H Shapiro

    Article first published online : 24 JAN 2013, DOI: 10.1111/j.1476-5381.2012.02222.x

  19. The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist

    European Journal of Organic Chemistry

    Volume 2012, Issue 27, September 2012, Pages: 5187–5194, Valentina Sepe, Raffaella Ummarino, Maria Valeria D'Auria, Barbara Renga, Stefano Fiorucci and Angela Zampella

    Article first published online : 19 JUL 2012, DOI: 10.1002/ejoc.201200619

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    Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes

    European Journal of Biochemistry

    Volume 268, Issue 24, December 2001, Pages: 6346–6358, Jean-Marc Pascussi, Lionel Drocourt, Sabine Gerbal-Chaloin, Jean-Michel Fabre, Patrick Maurel and Marie-José Vilarem

    Article first published online : 12 JAN 2002, DOI: 10.1046/j.0014-2956.2001.02540.x