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There are 3780 results for: content related to: Integrated Hedgehog signaling is induced following castration in human and murine prostate cancers

  1. Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b

    The Prostate

    Volume 72, Issue 15, November 2012, Pages: 1638–1647, Maria Karlou, Jing-Fang Lu, Guanglin Wu, Sankar Maity, Vassiliki Tzelepi, Nora M. Navone, Anh Hoang, Christopher J. Logothetis and Eleni Efstathiou

    Article first published online : 27 MAR 2012, DOI: 10.1002/pros.22517

  2. Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 5, Issue 1, January/February 2013, Pages: 83–100, Pamela V. Tran, Salil A. Lachke and Rolf W. Stottmann

    Article first published online : 11 OCT 2012, DOI: 10.1002/wsbm.1193

  3. Hedgehog signaling and congenital malformations

    Clinical Genetics

    Volume 67, Issue 3, March 2005, Pages: 193–208, E Nieuwenhuis and C-c Hui

    Article first published online : 20 OCT 2004, DOI: 10.1111/j.1399-0004.2004.00360.x

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    Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo

    Developmental Dynamics

    Volume 240, Issue 4, April 2011, Pages: 766–774, Juan Li, Chengbing Wang, Yong Pan, Zengliang Bai and Baolin Wang

    Article first published online : 18 FEB 2011, DOI: 10.1002/dvdy.22578

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    TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling

    International Journal of Cancer

    Volume 133, Issue 8, 15 October 2013, Pages: 1955–1966, Naokazu Ibuki, Mazyar Ghaffari, Mitali Pandey, Irene Iu, Ladan Fazli, Masahide Kashiwagi, Hideaki Tojo, Osamu Nakanishi, Martin E. Gleave and Michael E. Cox

    Article first published online : 6 MAY 2013, DOI: 10.1002/ijc.28193

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    Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo

    International Journal of Cancer

    Volume 132, Issue 7, 1 April 2013, Pages: 1516–1524, Malin Wickström, Cecilia Dyberg, Takashi Shimokawa, Jelena Milosevic, Ninib Baryawno, Ole M. Fuskevåg, Rolf Larsson, Per Kogner, Peter G. Zaphiropoulos and John I. Johnsen

    Article first published online : 3 OCT 2012, DOI: 10.1002/ijc.27820

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    Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines

    Developmental Dynamics

    Volume 237, Issue 8, August 2008, Pages: 2039–2052, Sonja K. Nielsen, Kjeld Møllgård, Christian A. Clement, Iben R. Veland, Aashir Awan, Bradley K. Yoder, Ivana Novak and Søren Tvorup Christensen

    Article first published online : 15 JUL 2008, DOI: 10.1002/dvdy.21610

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    Hedgehog signaling pathway as a therapeutic target in various types of cancer

    Cancer Science

    Volume 102, Issue 10, October 2011, Pages: 1756–1760, Hideya Onishi and Mitsuo Katano

    Article first published online : 25 JUL 2011, DOI: 10.1111/j.1349-7006.2011.02010.x

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    Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus

    International Journal of Cancer

    Volume 125, Issue 5, 1 September 2009, Pages: 1212–1221, Noriyuki Isohata, Kazuhiko Aoyagi, Tomoko Mabuchi, Hiroyuki Daiko, Masahide Fukaya, Hiroyuki Ohta, Kenji Ogawa, Teruhiko Yoshida and Hiroki Sasaki

    Article first published online : 27 FEB 2009, DOI: 10.1002/ijc.24400

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    Myofibroblast-derived PDGF-BB promotes hedgehog survival signaling in cholangiocarcinoma cells


    Volume 54, Issue 6, December 2011, Pages: 2076–2088, Christian D. Fingas, Steven F. Bronk, Nathan W. Werneburg, Justin L. Mott, Maria E. Guicciardi, Sophie C. Cazanave, Joachim C. Mertens, Alphonse E. Sirica and Gregory J. Gores

    Article first published online : 28 OCT 2011, DOI: 10.1002/hep.24588

  11. Inhibition of hedgehog signalling attenuates UVB-induced skin photoageing

    Experimental Dermatology

    Wanyeon Kim, EunGi Kim, Hee Jung Yang, TaeWoo Kwon, SeoYoung Han, Sungmin Lee, HyeSook Youn, Youngmi Jung, ChulHee Kang and BuHyun Youn

    Article first published online : 26 MAY 2015, DOI: 10.1111/exd.12735

  12. Developmental signaling: Does it bridge the gap between cilia dysfunction and renal cystogenesis?

    Birth Defects Research Part C: Embryo Today: Reviews

    Volume 102, Issue 2, June 2014, Pages: 159–173, Pamela V. Tran, Madhulika Sharma, Xiaogang Li and James P. Calvet

    Article first published online : 26 MAY 2014, DOI: 10.1002/bdrc.21065

  13. Hedgehog signaling is activated in canine transitional cell carcinoma and contributes to cell proliferation and survival

    Veterinary and Comparative Oncology

    T. L. Gustafson, B. E. Kitchell and B. Biller

    Article first published online : 10 APR 2015, DOI: 10.1111/vco.12149

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    Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development

    Development, Growth & Differentiation

    Volume 44, Issue 4, August 2002, Pages: 257–271, Yuka Takabatake, Takashi Takabatake, Satoru Sasagawa and Kazuhito Takeshima

    Article first published online : 2 SEP 2002, DOI: 10.1046/j.1440-169X.2002.00640.x

  15. You have full text access to this OnlineOpen article
    Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte

    European Journal of Immunology

    Volume 42, Issue 2, February 2012, Pages: 489–499, Anna L. Furmanski, Jose Ignacio Saldana, Nicola J. Rowbotham, Susan E. Ross and Tessa Crompton

    Article first published online : 16 DEC 2011, DOI: 10.1002/eji.201141758

  16. Hunting the Hedgehog Pathway

    Clinical Pharmacology & Therapeutics

    Volume 87, Issue 6, June 2010, Pages: 743–747, G J Weiss and D D Von Hoff

    Article first published online : 21 APR 2010, DOI: 10.1038/clpt.2010.34

  17. Primary cilia and graded Sonic Hedgehog signaling

    Wiley Interdisciplinary Reviews: Developmental Biology

    Volume 1, Issue 5, September/October 2012, Pages: 753–772, Noriaki Sasai and James Briscoe

    Article first published online : 4 APR 2012, DOI: 10.1002/wdev.43

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    Sonic Hedgehog signaling in the mammalian brain

    Journal of Neurochemistry

    Volume 113, Issue 3, May 2010, Pages: 576–590, Elisabeth Traiffort, Elodie Angot and Martial Ruat

    Article first published online : 10 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06642.x

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    Hedgehog signaling pathway regulates autophagy in human hepatocellular carcinoma cells


    Volume 58, Issue 3, September 2013, Pages: 995–1010, Ying Wang, Chang Han, Lu Lu, Susan Magliato and Tong Wu

    Article first published online : 30 JUL 2013, DOI: 10.1002/hep.26394

  20. You have full text access to this OnlineOpen article
    Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans


    Volume 56, Issue 3, September 2012, Pages: 1108–1116, James Pritchett, Emma Harvey, Varinder Athwal, Andrew Berry, Cliff Rowe, Fiona Oakley, Anna Moles, Derek A. Mann, Nicoletta Bobola, Andrew D. Sharrocks, Brian J. Thomson, Abed M. Zaitoun, William L. Irving, Indra N. Guha, Neil A. Hanley and Karen Piper Hanley

    Article first published online : 28 AUG 2012, DOI: 10.1002/hep.25758