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There are 9419 results for: content related to: Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex

  1. You have full text access to this OnlineOpen article
    A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination

    The EMBO Journal

    Volume 36, Issue 9, 2 May 2017, Pages: 1243–1260, Xu Wang, Wei Cao, Jianjun Zhang, Ming Yan, Qin Xu, Xiangbing Wu, Lixin Wan, Zhiyuan Zhang, Chenping Zhang, Xing Qin, Meng Xiao, Dongxia Ye, Yuyang Liu, Zeguang Han, Shaomeng Wang, Li Mao, Wenyi Wei and Wantao Chen

    Version of Record online : 20 MAR 2017, DOI: 10.15252/embj.201694058

  2. You have free access to this content
    Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool

    STEM CELLS

    Volume 31, Issue 9, September 2013, Pages: 1910–1920, Ewa Malgorzata Michalak, Karim Nacerddine, Alexandra Pietersen, Vincent Beuger, Inka Pawlitzky, Paulien Cornelissen-Steijger, Ellen Wientjens, Ellen Tanger, Jost Seibler, Maarten van Lohuizen and Jos Jonkers

    Version of Record online : 4 OCT 2013, DOI: 10.1002/stem.1437

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    EZH2: an emerging role in melanoma biology and strategies for targeted therapy

    Pigment Cell & Melanoma Research

    Volume 28, Issue 1, January 2015, Pages: 21–30, Jessamy Tiffen, Stuart J. Gallagher and Peter Hersey

    Version of Record online : 27 JUN 2014, DOI: 10.1111/pcmr.12280

  4. You have full text access to this OnlineOpen article
    Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 531–547, Yung-Luen Yu, Ruey-Hwang Chou, Woei-Cherng Shyu, Shu-Ching Hsieh, Chen-Shiou Wu, Shu-Ya Chiang, Wei-Jung Chang, Jia-Ni Chen, Yen-Ju Tseng, Yu-Hsuan Lin, Wei Lee, Su-Peng Yeh, Jennifer L. Hsu, Cheng-Chieh Yang, Shih-Chieh Hung and Mien-Chie Hung

    Version of Record online : 25 MAR 2013, DOI: 10.1002/emmm.201201783

  5. Histone methyltransferase enhancer of zeste homolog 2 regulates Schwann cell differentiation

    Glia

    Volume 60, Issue 11, November 2012, Pages: 1696–1708, André Heinen, Nevena Tzekova, Nina Graffmann, Klintsy Julieta Torres, Markus Uhrberg, Hans-Peter Hartung and Patrick Küry

    Version of Record online : 20 JUL 2012, DOI: 10.1002/glia.22388

  6. EZH2–miR-30d–KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis

    The Journal of Pathology

    Volume 232, Issue 3, February 2014, Pages: 308–318, Pingyu Zhang, Jeannine Garnett, Chad J Creighton, Ghadah Abbas Al Sannaa, Davis R Igram, Alexander Lazar, Xiuping Liu, Changgong Liu and Raphael E Pollock

    Version of Record online : 13 JAN 2014, DOI: 10.1002/path.4294

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    Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma

    Cancer

    Volume 118, Issue 11, 1 June 2012, Pages: 2858–2871, Wei Cao, Zhien Feng, Zhibin Cui, Chenping Zhang, Zhaoyao Sun, Li Mao and Wantao Chen

    Version of Record online : 11 OCT 2011, DOI: 10.1002/cncr.26575

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    Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

    Hepatology

    Volume 56, Issue 2, August 2012, Pages: 622–631, Sandy Leung-Kuen Au, Carmen Chak-Lui Wong, Joyce Man-Fong Lee, Dorothy Ngo-Yin Fan, Felice Hoching Tsang, Irene Oi-Lin Ng and Chun-Ming Wong

    Version of Record online : 11 JUN 2012, DOI: 10.1002/hep.25679

  9. You have full text access to this Open Access content
    EZH2 regulates expression of p57 and contributes to progression of ovarian cancer in vitro and in vivo

    Cancer Science

    Volume 102, Issue 3, March 2011, Pages: 530–539, Jianfeng Guo, Jing Cai, Lili Yu, Huijuan Tang, Chunyan Chen and Zehua Wang

    Version of Record online : 18 JAN 2011, DOI: 10.1111/j.1349-7006.2010.01836.x

  10. MiR-138 inhibits EZH2 methyltransferase expression and methylation of histone H3 at lysine 27, and affects thermotolerance acquisition

    European Journal of Neuroscience

    Volume 33, Issue 2, January 2011, Pages: 224–235, Tatiana Kisliouk, Sara Yosefi and Noam Meiri

    Version of Record online : 11 NOV 2010, DOI: 10.1111/j.1460-9568.2010.07493.x

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    EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

    The EMBO Journal

    Volume 22, Issue 20, October 15, 2003, Pages: 5323–5335, Adrian P. Bracken, Diego Pasini, Maria Capra, Elena Prosperini, Elena Colli and Kristian Helin

    Version of Record online : 15 OCT 2003, DOI: 10.1093/emboj/cdg542

  12. You have full text access to this Open Access content
    EZH2 Is Required for Breast and Pancreatic Cancer Stem Cell Maintenance and Can Be Used as a Functional Cancer Stem Cell Reporter

    STEM CELLS Translational Medicine

    Volume 2, Issue 1, January 2013, Pages: 43–52, Lilian E. van Vlerken, Christine M. Kiefer, Chris Morehouse, Ying Li, Chris Groves, Susan D. Wilson, Yihong Yao, Robert E. Hollingsworth and Elaine M. Hurt

    Version of Record online : 27 DEC 2012, DOI: 10.5966/sctm.2012-0036

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    Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

    Cancer Science

    Volume 102, Issue 7, July 2011, Pages: 1298–1305, Masashi Takawa, Ken Masuda, Masaki Kunizaki, Yataro Daigo, Katsunori Takagi, Yukiko Iwai, Hyun-Soo Cho, Gouji Toyokawa, Yuka Yamane, Kazuhiro Maejima, Helen I. Field, Takaaki Kobayashi, Takayuki Akasu, Masanori Sugiyama, Eijyu Tsuchiya, Yutaka Atomi, Bruce A. J. Ponder, Yusuke Nakamura and Ryuji Hamamoto

    Version of Record online : 26 MAY 2011, DOI: 10.1111/j.1349-7006.2011.01958.x

  14. A non-canonical function of Ezh2 preserves immune homeostasis

    EMBO reports

    Volume 18, Issue 4, April 2017, Pages: 619–631, Ajithkumar Vasanthakumar, Dakang Xu, Aaron TL Lun, Andrew J Kueh, Klaas PJM van Gisbergen, Nadia Iannarella, Xiaofang Li, Liang Yu, Die Wang, Bryan RG Williams, Stanley CW Lee, Ian J Majewski, Dale I Godfrey, Gordon K Smyth, Warren S Alexander, Marco J Herold, Axel Kallies, Stephen L Nutt and Rhys S Allan

    Version of Record online : 21 FEB 2017, DOI: 10.15252/embr.201643237

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    EZH2 coupled with HOTAIR to silence MicroRNA-34a by the induction of heterochromatin formation in human pancreatic ductal adenocarcinoma

    International Journal of Cancer

    Volume 140, Issue 1, 1 January 2017, Pages: 120–129, Chi-Han Li, Zhangang Xiao, Joanna Hung–Man Tong, Ka-Fai To, Xiangdong Fang, Alfred SL Cheng and Yangchao Chen

    Version of Record online : 19 SEP 2016, DOI: 10.1002/ijc.30414

  16. Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma

    Molecular Carcinogenesis

    Volume 52, Issue 3, March 2013, Pages: 229–236, Cheng Wang, Xiqiang Liu, Zujian Chen, Hongzhang Huang, Yi Jin, Antonia Kolokythas, Anxun Wang, Yang Dai, David T.W. Wong and Xiaofeng Zhou

    Version of Record online : 7 DEC 2011, DOI: 10.1002/mc.21848

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    EZH2 phosphorylation regulates Tat-induced HIV-1 transactivation via ROS/Akt signaling pathway

    FEBS Letters

    Volume 589, Issue 24PartB, December 21, 2015, Pages: 4106–4111, Hong-Sheng Zhang, Yang Liu, Tong-Chao Wu, Guang-Yuan Du and Feng-Juan Zhang

    Version of Record online : 26 NOV 2015, DOI: 10.1016/j.febslet.2015.11.033

  18. Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications

    Medicinal Research Reviews

    Volume 35, Issue 6, November 2015, Pages: 1220–1267, Wei Wang, Jiang-Jiang Qin, Sukesh Voruganti, Subhasree Nag, Jianwei Zhou and Ruiwen Zhang

    Version of Record online : 30 JUL 2015, DOI: 10.1002/med.21358

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    YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK

    British Journal of Pharmacology

    Volume 171, Issue 17, September 2014, Pages: 4010–4025, Ling-Chu Chang, Hui-Yi Lin, Meng-Tung Tsai, Ruey-Hwang Chou, Fang-Yu Lee, Che-Ming Teng, Min-Tsang Hsieh, Hsin-Yi Hung, Li-Jiau Huang, Yung-Luen Yu and Sheng-Chu Kuo

    Version of Record online : 25 JUL 2014, DOI: 10.1111/bph.12708

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    EZH2 and KDM6A Act as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

    STEM CELLS

    Volume 32, Issue 3, March 2014, Pages: 802–815, Sarah Hemming, Dimitrios Cakouros, Sandra Isenmann, Lachlan Cooper, Danijela Menicanin, Andrew Zannettino and Stan Gronthos

    Version of Record online : 19 FEB 2014, DOI: 10.1002/stem.1573