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There are 9500 results for: content related to: Crystal structure of the type II 3-dehydroquinase from Helicobacter pylori

  1. Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy

    ChemMedChem

    Volume 7, Issue 6, June 2012, Pages: 1031–1043, Anh Thu Tran, Dr. Nicholas P. West, Prof. Warwick J. Britton and Dr. Richard J. Payne

    Article first published online : 27 MAR 2012, DOI: 10.1002/cmdc.201100606

  2. Structural study of the type II 3-dehydroquinate dehydratase from Actinobacillus pleuropneumoniae

    Acta Crystallographica Section D

    Volume 60, Issue 3, March 2004, Pages: 463–471, D. Maes, L. A. Gonzalez-Ramirez, J. Lopez-Jaramillo, B. Yu, H. De Bondt, I. Zegers, E. Afonina, J. M. Garcia-Ruiz and S. Gulnik

    DOI: 10.1107/S090744490302969X

  3. You have free access to this content
    Biophysical and kinetic analysis of wild-type and site-directed mutants of the isolated and native dehydroquinate synthase domain of the AROM protein

    Protein Science

    Volume 13, Issue 8, August 2004, Pages: 2108–2119, Alison Park, Heather K. Lamb, Charlie Nichols, Jonathan D. Moore, Katherine A. Brown, Alan Cooper, Ian G. Charles, David K. Stammers and Alastair R. Hawkins

    Article first published online : 1 JAN 2009, DOI: 10.1110/ps.04705404

  4. Discovery of Schaeffer’s Acid Analogues as Lead Structures of Mycobacterium tuberculosis Type II Dehydroquinase Using a Rational Drug Design Approach

    ChemMedChem

    Volume 8, Issue 1, January 2013, Pages: 54–58, Dr. Marco F. Schmidt, Dr. Oliver Korb, Dr. Nigel I. Howard, Dr. Marcio V. B. Dias, Prof. Dr. Tom L. Blundell and Prof. Dr. Chris Abell

    Article first published online : 21 NOV 2012, DOI: 10.1002/cmdc.201200508

  5. You have free access to this content
    Domain structure and interaction within the pentafunctional arom polypeptide

    European Journal of Biochemistry

    Volume 196, Issue 3, March 1991, Pages: 717–724, Alastair R. HAWKINS and Melanie SMITH

    Article first published online : 3 MAR 2005, DOI: 10.1111/j.1432-1033.1991.tb15870.x

  6. Structure of type II dehydroquinase from Pseudomonas aeruginosa

    Acta Crystallographica Section F

    Volume 70, Issue 11, November 2014, Pages: 1485–1491, Scott Reiling, Alan Kelleher, Monica M. Matsumoto, Gonteria Robinson and Oluwatoyin A. Asojo

    DOI: 10.1107/S2053230X14020214

  7. You have free access to this content
    Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis

    ChemMedChem

    Volume 10, Issue 1, January 2015, Pages: 116–133, Dr. Nigel I. Howard, Dr. Marcio V. B. Dias, Dr. Fabienne Peyrot, Dr. Liuhong Chen, Dr. Marco F. Schmidt, Prof. Tom L. Blundell and Prof. Chris Abell

    Article first published online : 18 SEP 2014, DOI: 10.1002/cmdc.201402298

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    Reassessing the type I dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants

    Protein Science

    Volume 22, Issue 4, April 2013, Pages: 418–424, Samuel H. Light, Wayne F. Anderson and Arnon Lavie

    Article first published online : 11 FEB 2013, DOI: 10.1002/pro.2218

  9. The kinetic model of the shikimate pathway as a tool to optimize enzyme assays for high-throughput screening

    Biotechnology and Bioengineering

    Volume 95, Issue 4, 5 November 2006, Pages: 560–571, Michael Noble, Yugesh Sinha, Aleksey Kolupaev, Oleg Demin, David Earnshaw, Frank Tobin, Joshua West, John D. Martin, Chunyan Qiu, Wu-Schyong Liu, Walter E. DeWolf Jr., David Tew and Igor I. Goryanin

    Article first published online : 18 AUG 2006, DOI: 10.1002/bit.20772

  10. Aggregation und Trennbarkeit der Enzyme des Shikimat-Pathway bei Hefen

    Zeitschrift für allgemeine Mikrobiologie

    Volume 21, Issue 6, 1981, Pages: 417–422, Dr. R. Bode and D. Birnbaum

    Article first published online : 24 JAN 2007, DOI: 10.1002/jobm.19810210602

  11. Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity

    Acta Crystallographica Section D

    Volume 58, Issue 5, May 2002, Pages: 798–804, Wen-Hwa Lee, Luis Augusto Perles, Ronaldo A. P. Nagem, Annette K. Shrive, Alastair Hawkins, Lindsay Sawyer and Igor Polikarpov

    DOI: 10.1107/S0907444902003918

  12. Structure of the `open' form of Aspergillus nidulans 3-dehydroquinate synthase at 1.7 Å resolution from crystals grown following enzyme turnover

    Acta Crystallographica Section D

    Volume 60, Issue 5, May 2004, Pages: 971–973, C. E. Nichols, A. R. Hawkins and D. K. Stammers

    DOI: 10.1107/S0907444904004743

  13. Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase

    Acta Crystallographica Section D

    Volume 57, Issue 2, February 2001, Pages: 306–309, C. E. Nichols, J. Ren, H. Lamb, F. Haldane, A. R. Hawkins and D. K. Stammers

    DOI: 10.1107/S0907444900019429

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    Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments

    Proteins: Structure, Function, and Bioinformatics

    Volume 56, Issue 3, 15 August 2004, Pages: 625–628, C.E. Nichols, M. Lockyer, A.R. Hawkins and D.K. Stammers

    Article first published online : 14 MAY 2004, DOI: 10.1002/prot.20165

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    Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8 showing functional importance of the dimeric state

    Proteins: Structure, Function, and Bioinformatics

    Volume 58, Issue 1, 1 January 2005, Pages: 249–252, Michihiro Sugahara, Yuichi Nodake, Mitsuaki Sugahara and Naoki Kunishima

    Article first published online : 26 OCT 2004, DOI: 10.1002/prot.20281

  16. Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase: Synthesis, Biological Evaluation, and NMR Studies

    ChemMedChem

    Volume 3, Issue 5, May 19, 2008, Pages: 756–770, Cristina Sánchez-Sixto, Verónica F. V. Prazeres, Luis Castedo, Se Won Suh, Heather Lamb, Alastair R. Hawkins, Francisco Javier Cañada, Jesús Jiménez-Barbero and Concepción González-Bello

    Article first published online : 17 JAN 2008, DOI: 10.1002/cmdc.200700307

  17. Type II dehydroquinase: molecular replacement with many copies

    Acta Crystallographica Section D

    Volume 64, Issue 1, January 2008, Pages: 108–118, Kirsty Anne Stewart, David Alexander Robinson and Adrian Jonathan Lapthorn

    DOI: 10.1107/S0907444907054923

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    The Molecular Biology of Multidomain Proteins Selected Examples

    European Journal of Biochemistry

    Volume 232, Issue 1, August 1995, Pages: 7–18, Alastair R. Hawkins and Heather K. Lamb

    Article first published online : 3 MAR 2005, DOI: 10.1111/j.1432-1033.1995.tb20775.x

  19. Synthesis and Evaluation of Potent Ene–yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug Leads

    ChemMedChem

    Volume 6, Issue 2, February 7, 2011, Pages: 262–265, Anh Thu Tran, Dr. Katie M. Cergol, Dr. Nicholas P. West, Elizabeth J. Randall, Prof. Warwick J. Britton, Syed Ali Imran Bokhari, Musadiq Ibrahim, Dr. Adrian J. Lapthorn and Dr. Richard J. Payne

    Article first published online : 4 NOV 2010, DOI: 10.1002/cmdc.201000399

  20. Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors

    ChemMedChem

    Volume 8, Issue 5, May 2013, Pages: 740–747, Antonio Peón, Dr. Claire Coderch, Prof. Federico Gago and Prof. Concepción González-Bello

    Article first published online : 1 MAR 2013, DOI: 10.1002/cmdc.201300013