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There are 35312 results for: content related to: Structural facets of disease-linked human prion protein mutants: A molecular dynamic study

  1. Copper(II) Interaction with Prion Peptide Fragments Encompassing Histidine Residues Within and Outside the Octarepeat Domain: Speciation, Stability Constants and Binding Details

    Chemistry - A European Journal

    Volume 13, Issue 25, August 27, 2007, Pages: 7129–7143, Katalin Ősz, Zoltán Nagy, Giuseppe Pappalardo, Giuseppe Di Natale, Daniele Sanna, Giovanni Micera, Enrico Rizzarelli and Imre Sóvágó

    Article first published online : 13 JUN 2007, DOI: 10.1002/chem.200601568

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    Putative aggregation initiation sites in prion protein

    FEBS Letters

    Volume 580, Issue 8, April 03, 2006, Pages: 2033–2040, Jan Ziegler, Christine Viehrig, Stefan Geimer, Paul Rösch and Stephan Schwarzinger

    Article first published online : 10 MAR 2006, DOI: 10.1016/j.febslet.2006.03.002

  3. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation

    Annals of Neurology

    Volume 78, Issue 4, October 2015, Pages: 540–553, Joel C. Watts, Kurt Giles, Ana Serban, Smita Patel, Abby Oehler, Sumita Bhardwaj, Shenheng Guan, Michael D. Greicius, Bruce L. Miller, Stephen J. DeArmond, Michael D. Geschwind and Stanley B. Prusiner

    Article first published online : 25 AUG 2015, DOI: 10.1002/ana.24463

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    Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 339–356, Agnes Lau, Alex McDonald, Nathalie Daude, Charles E Mays, Eric D Walter, Robin Aglietti, Robert CC Mercer, Serene Wohlgemuth, Jacques van der Merwe, Jing Yang, Hristina Gapeshina, Chae Kim, Jennifer Grams, Beipei Shi, Holger Wille, Aru Balachandran, Gerold Schmitt-Ulms, Jiri G Safar, Glenn L Millhauser and David Westaway

    Article first published online : 6 FEB 2015, DOI: 10.15252/emmm.201404588

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    Modelling charge interactions in the prion protein: predictions for pathogenesis

    FEBS Letters

    Volume 450, Issue 1-2, April 30, 1999, Pages: 144–148, James Warwicker

    Article first published online : 21 MAY 1999, DOI: 10.1016/S0014-5793(99)00428-7

  6. Assessing the acid–base and conformational properties of histidine residues in human prion protein (125–228) by means of pKa calculations and molecular dynamics simulations

    Proteins: Structure, Function, and Bioinformatics

    Volume 64, Issue 1, 1 July 2006, Pages: 167–177, Emma Langella, Roberto Improta, Orlando Crescenzi and Vincenzo Barone

    Article first published online : 25 APR 2006, DOI: 10.1002/prot.20979

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    A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

    Journal of Neurochemistry

    Volume 108, Issue 1, January 2009, Pages: 44–56, Heather M. Christensen and David A. Harris

    Article first published online : 10 OCT 2008, DOI: 10.1111/j.1471-4159.2008.05719.x

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    Oxidative folding of murine prion mPrP(23–231)

    European Journal of Biochemistry

    Volume 268, Issue 13, July 2001, Pages: 3767–3773, Bao-Yuan Lu, Pamela J. Beck and Jui-Yoa Chang

    Article first published online : 20 DEC 2001, DOI: 10.1046/j.1432-1327.2001.02283.x

  9. Biochemistry and Structural Biology of Mammalian Prion Disease

    Standard Article

    Protein Science Encyclopedia

    Rudi Glockshuber

    Published Online : 15 MAR 2008, DOI: 10.1002/9783527610754.md07

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    Leu138 in bovine prion peptide fibrils is involved in seeding discrimination related to codon 129 M/V polymorphism in the prion peptide seeding experiment

    The FEBS Journal

    Volume 278, Issue 22, November 2011, Pages: 4351–4361, Tai-Yan Liao, Lily Y.-L. Lee and Rita P.-Y. Chen

    Article first published online : 10 OCT 2011, DOI: 10.1111/j.1742-4658.2011.08353.x

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    Dynamics of a truncated prion protein, PrP(113–231), from 15N NMR relaxation: Order parameters calculated and slow conformational fluctuations localized to a distinct region

    Protein Science

    Volume 18, Issue 2, February 2009, Pages: 410–423, Denis B. D. O'Sullivan, Christopher E. Jones, Salama R. Abdelraheim, Marcus W. Brazier, Harold Toms, David R. Brown and John H. Viles

    Article first published online : 29 DEC 2008, DOI: 10.1002/pro.44

  12. Prions of Humans and Animals

    Standard Article

    Topley and Wilson's Microbiology and Microbial Infections

    Adriano Aguzzi

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470688618.taw0267

  13. Hydrogen/deuterium exchange mass spectrometry identifies two highly protected regions in recombinant full-length prion protein amyloid fibrils

    Journal of Mass Spectrometry

    Volume 44, Issue 6, June 2009, Pages: 965–977, Alexis Nazabal, Simone Hornemann, Adriano Aguzzi and Renato Zenobi

    Article first published online : 12 MAR 2009, DOI: 10.1002/jms.1572

  14. Calnexin inhibits thermal aggregation and neurotoxicity of prion protein

    Journal of Cellular Biochemistry

    Volume 111, Issue 2, 1 October 2010, Pages: 343–349, Wenxi Wang, Rui Chen, Kan Luo, Di Wu, Liqin Huang, Tao Huang and Gengfu Xiao

    Article first published online : 12 MAY 2010, DOI: 10.1002/jcb.22698

  15. Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: Dependence of conformation on pH

    Proteins: Structure, Function, and Bioinformatics

    Volume 44, Issue 2, 1 August 2001, Pages: 110–118, Yoichi Matsunaga, David Peretz, Anthony Williamson, Dennis Burton, Ingrid Mehlhorn, Darlene Groth, Fred E. Cohen, Stanley B. Prusiner and Michael A. Baldwin

    Article first published online : 21 MAY 2001, DOI: 10.1002/prot.1077

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    The cellular form of the prion protein is involved in controlling cell cycle dynamics, self-renewal, and the fate of human embryonic stem cell differentiation

    Journal of Neurochemistry

    Volume 124, Issue 3, February 2013, Pages: 310–322, Young Jin Lee and Ilia V. Baskakov

    Article first published online : 3 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07913.x

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    The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein

    The EMBO Journal

    Volume 20, Issue 21, November 1, 2001, Pages: 5863–5875, Sabine Gauczynski, Jean-Michel Peyrin, Stéphane Haïk, Christoph Leucht, Christoph Hundt, Roman Rieger, Susanne Krasemann, Jean-Philippe Deslys, Dominique Dormont, Corinne Ida Lasmézas and Stefan Weiss

    Article first published online : 1 NOV 2001, DOI: 10.1093/emboj/20.21.5863

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    PrP(106–126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc

    FEBS Letters

    Volume 579, Issue 19, August 01, 2005, Pages: 4099–4106, Rosalina Gavín, Nathalie Braun, Oriol Nicolas, Beatriz Parra, Jesus Mariano Ureña, Ana Mingorance, Eduardo Soriano, Juan María Torres, Adriano Aguzzi and José Antonio del Río

    Article first published online : 5 JUL 2005, DOI: 10.1016/j.febslet.2005.06.037

  19. Utilizing NMR and EPR spectroscopy to probe the role of copper in prion diseases

    Magnetic Resonance in Chemistry

    Volume 51, Issue 5, May 2013, Pages: 255–268, Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Xianrong Guo, Suliman Al-Ghamdi and Harbi T. Al-Masri

    Article first published online : 24 FEB 2013, DOI: 10.1002/mrc.3936

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    Ionic mechanisms of action of prion protein fragment PrP(106–126) in rat basal forebrain neurons

    Journal of Neuroscience Research

    Volume 88, Issue 10, 1 August 2010, Pages: 2217–2227, Kwai Alier, Zongming Li, David MacTavish, David Westaway and Jack H. Jhamandas

    Article first published online : 19 FEB 2010, DOI: 10.1002/jnr.22372