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There are 19274 results for: content related to: p H-selective mutagenesis of protein–protein interfaces: In silico design of therapeutic antibodies with prolonged half-life

  1. The multiple facets of FcRn in immunity

    Immunological Reviews

    Volume 268, Issue 1, November 2015, Pages: 253–268, Nigel M. Stapleton, Helga K. Einarsdóttir, Annette M. Stemerding and Gestur Vidarsson

    Version of Record online : 26 OCT 2015, DOI: 10.1111/imr.12331

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    Effect of Individual Fc Methionine Oxidation on FcRn Binding: Met252 Oxidation Impairs FcRn Binding More Profoundly than Met428 Oxidation

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 2, February 2015, Pages: 368–377, Xuan Gao, Junyan A. Ji, Karthik Veeravalli, Y. John Wang, Taylor Zhang, William Mcgreevy, Kai Zheng, Robert F. Kelley, Michael W. Laird, Jun Liu and Mary Cromwell

    Version of Record online : 29 AUG 2014, DOI: 10.1002/jps.24136

  3. The Biology of the Neonatal Fc Receptor (FcRn)

    Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives

    Roland Kontermann, Pages: 141–155, 2012

    Published Online : 6 FEB 2012, DOI: 10.1002/9783527644827.ch8

  4. The Diverse Roles of FcRn: Implications for Antibody Engineering

    Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives

    E. Sally Ward, Raimund J. Ober, Pages: 207–222, 2012

    Published Online : 6 FEB 2012, DOI: 10.1002/9783527644827.ch11

  5. Accelerating antibody discovery using transgenic animals overexpressing the neonatal Fc receptor as a result of augmented humoral immunity

    Immunological Reviews

    Volume 268, Issue 1, November 2015, Pages: 269–287, Judit Cervenak, Roland Kurrle and Imre Kacskovics

    Version of Record online : 26 OCT 2015, DOI: 10.1111/imr.12364

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    Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor

    Traffic

    Volume 7, Issue 9, September 2006, Pages: 1127–1142, Devin B. Tesar, Noreen E. Tiangco and Pamela J. Bjorkman

    Version of Record online : 29 JUN 2006, DOI: 10.1111/j.1600-0854.2006.00457.x

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    Comparison of FcRn- and pIgR-Mediated Transport in MDCK Cells by Fluorescence Confocal Microscopy

    Traffic

    Volume 11, Issue 9, September 2010, Pages: 1205–1220, Galina V. Jerdeva, Devin B. Tesar, Kathryn E. Huey-Tubman, Mark S. Ladinsky, Scott E. Fraser and Pamela J. Bjorkman

    Version of Record online : 26 MAY 2010, DOI: 10.1111/j.1600-0854.2010.01083.x

  8. Placental Transfer of Fc-Containing Biopharmaceuticals across Species, an Industry Survey Analysis

    Birth Defects Research Part B: Developmental and Reproductive Toxicology

    Volume 98, Issue 6, December 2013, Pages: 459–485, Christopher J. Bowman, William J. Breslin, Anu V. Connor, Pauline L. Martin, Graeme J. Moffat, Lakshmi Sivaraman, M. Belen Tornesi and Simon Chivers

    Version of Record online : 3 JAN 2014, DOI: 10.1002/bdrb.21089

  9. Embryo-Fetal Transfer of Bevacizumab (Avastin) in the Rat Over the Course of Gestation and the Impact of Neonatal Fc Receptor (FcRn) Binding

    Birth Defects Research Part B: Developmental and Reproductive Toxicology

    Volume 95, Issue 5, October 2012, Pages: 363–375, Mitchell Thorn, Nicole Piche-Nicholas, Donald Stedman, Scott W. Davenport, Ning Zhang, Mark Collinge and Christopher J. Bowman

    Version of Record online : 11 SEP 2012, DOI: 10.1002/bdrb.21026

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    Redistribution of the sheep neonatal Fc receptor in the mammary gland around the time of parturition in ewes and its localization in the small intestine of neonatal lambs

    Immunology

    Volume 107, Issue 3, November 2002, Pages: 288–296, Balázs Mayer, Anna Zolnai, László V. Frenyó, Veronika Jancsik, Zoltán Szentirmay, Lennart Hammarström and Imre Kacskovics

    Version of Record online : 8 NOV 2002, DOI: 10.1046/j.1365-2567.2002.01514.x

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    Identification and function of neonatal Fc receptor in mammary gland of lactating mice

    European Journal of Immunology

    Volume 29, Issue 8, August 1999, Pages: 2515–2523, Petru Cianga, Corneliu Medesan, James A. Richardson, Victor Ghetie and E. Sally Ward

    Version of Record online : 5 AUG 1999, DOI: 10.1002/(SICI)1521-4141(199908)29:08<2515::AID-IMMU2515>3.0.CO;2-D

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    Analyses of the Recycling Receptor, FcRn, in Live Cells Reveal Novel Pathways for Lysosomal Delivery

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    Volume 10, Issue 5, May 2009, Pages: 600–614, Zhuo Gan, Sripad Ram, Carlos Vaccaro, Raimund J. Ober and E. Sally Ward

    Version of Record online : 24 JAN 2009, DOI: 10.1111/j.1600-0854.2009.00887.x

  13. Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation

    Immunological Reviews

    Volume 270, Issue 1, March 2016, Pages: 132–151, Tomoyuki Igawa, Kenta Haraya and Kunihiro Hattori

    Version of Record online : 10 FEB 2016, DOI: 10.1111/imr.12392

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    IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand-induced redistribution

    The EMBO Journal

    Volume 21, Issue 4, February 15, 2002, Pages: 590–601, T.S. Ramalingam, Scott A. Detmer, W.Lance Martin and Pamela J. Bjorkman

    Version of Record online : 15 FEB 2002, DOI: 10.1093/emboj/21.4.590

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    Retraction: IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand-induced redistribution

    Vol. 21, Issue 21, 5953, Version of Record online: 1 NOV 2002

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    Comparative studies of rat IgG to further delineate the Fc  :  FcRn interaction site

    European Journal of Immunology

    Volume 28, Issue 7, July 1998, Pages: 2092–2100, Corneliu Medesan, Petru Cianga, Mark Mummert, Diana Stanescu, Victor Ghetie and E. Sally Ward

    Version of Record online : 14 DEC 1998, DOI: 10.1002/(SICI)1521-4141(199807)28:07<2092::AID-IMMU2092>3.0.CO;2-E

  16. Quantitative methods for developing Fc mutants with extended half-lives

    Biotechnology and Bioengineering

    Volume 92, Issue 6, 20 December 2005, Pages: 748–760, Daniel T. Kamei, Bert J. Lao, Margaret Speed Ricci, Rohini Deshpande, Han Xu, Bruce Tidor and Douglas A. Lauffenburger

    Version of Record online : 31 AUG 2005, DOI: 10.1002/bit.20624

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    Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

    The FEBS Journal

    Volume 275, Issue 16, August 2008, Pages: 4097–4110, Jan T. Andersen, Sune Justesen, Burkhard Fleckenstein, Terje E. Michaelsen, Gøril Berntzen, Vania E. Kenanova, Muluneh B. Daba, Vigdis Lauvrak, Søren Buus and Inger Sandlie

    Version of Record online : 15 JUL 2008, DOI: 10.1111/j.1742-4658.2008.06551.x

  18. FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice

    Clinical & Experimental Allergy

    Volume 42, Issue 12, December 2012, Pages: 1791–1800, S. Paveglio, L. Puddington, E. Rafti and A. P. Matson

    Version of Record online : 26 NOV 2012, DOI: 10.1111/j.1365-2222.2012.04043.x

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    Alteration of the N-glycome of bovine milk glycoproteins during early lactation

    The FEBS Journal

    Volume 278, Issue 19, October 2011, Pages: 3769–3781, Shota Takimori, Hideyuki Shimaoka, Jun-Ichi Furukawa, Tadashi Yamashita, Maho Amano, Naoki Fujitani, Yasuhiro Takegawa, Lennart Hammarström, Imre Kacskovics, Yasuro Shinohara and Shin-Ichiro Nishimura

    Version of Record online : 8 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08299.x

  20. Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design

    Drug Delivery in Oncology: From Basic Research to Cancer Therapy

    Jan Terje Andersen, Inger Sandlie, Pages: 85–120, 2011

    Published Online : 16 DEC 2011, DOI: 10.1002/9783527634057.ch4