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There are 39940 results for: content related to: Molecular dynamics analyses of the dissociation process of ADP from Hsp90

  1. Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation

    Medicinal Research Reviews

    Volume 26, Issue 3, May 2006, Pages: 310–338, Brian S. J. Blagg and Timothy D. Kerr

    Version of Record online : 29 DEC 2005, DOI: 10.1002/med.20052

  2. Hsp90 Inhibitors

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Brian S. J. Blagg and M. Kyle Hadden

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc212

  3. Heat-Shock Protein 90 (Hsp90) as Anticancer Target for Drug Discovery: An Ample Computational Perspective

    Chemical Biology & Drug Design

    Volume 86, Issue 5, November 2015, Pages: 1131–1160, Hezekiel M. Kumalo, Soumendranath Bhakat and Mahmoud E. Soliman

    Version of Record online : 11 JUN 2015, DOI: 10.1111/cbdd.12582

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    Heat shock protein 90 and its co-chaperone protein phosphatase 5 interact with distinct regions of the tomato I-2 disease resistance protein

    The Plant Journal

    Volume 43, Issue 2, July 2005, Pages: 284–298, Sergio De La Fuente Bentem van, Jack H. Vossen, Klaas Jan de Vries, Saskia van Wees, Wladimir I.L. Tameling, Henk L. Dekker, Chris G. de Koster, Michel A. Haring, Frank L.W. Takken and Ben J.C. Cornelissen

    Version of Record online : 17 JUN 2005, DOI: 10.1111/j.1365-313X.2005.02450.x

  5. Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands

    Chemistry - A European Journal

    Volume 21, Issue 39, September 21, 2015, Pages: 13598–13608, Dr. Sara Sattin, Dr. Jiahui Tao, Dr. Gerolamo Vettoretti, Dr. Elisabetta Moroni, Dr. Marzia Pennati, Dr. Alessia Lopergolo, Dr. Laura Morelli, Dr. Antonella Bugatti, Dr. Abbey Zuehlke, Dr. Mike Moses, Dr. Thomas Prince, Dr. Toshiki Kijima, Dr. Kristin Beebe, Dr. Marco Rusnati, Dr. Len Neckers, Dr. Nadia Zaffaroni, Prof. David A. Agard, Prof. Anna Bernardi and Dr. Giorgio Colombo

    Version of Record online : 18 AUG 2015, DOI: 10.1002/chem.201502211

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    Regulation of Embryonic Stem Cell Pluripotency by Heat Shock Protein 90

    STEM CELLS

    Volume 30, Issue 8, August 2012, Pages: 1624–1633, Eric Bradley, Erhard Bieberich, Nahid F. Mivechi, Dantera Tangpisuthipongsa and Guanghu Wang

    Version of Record online : 24 JUL 2012, DOI: 10.1002/stem.1143

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    Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol

    The FEBS Journal

    Volume 274, Issue 17, September 2007, Pages: 4453–4463, Stefan H. Millson, Andrew W. Truman, Attila Rácz, Bin Hu, Barry Panaretou, James Nuttall, Mehdi Mollapour, Csaba Söti and Peter W. Piper

    Version of Record online : 6 AUG 2007, DOI: 10.1111/j.1742-4658.2007.05974.x

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    PLCγ1–PKCγ Signaling-Mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis

    Traffic

    Volume 15, Issue 8, August 2014, Pages: 861–878, Jian Yang, Xiaomin Song, Yang Chen, Xin-an Lu, Yan Fu and Yongzhang Luo

    Version of Record online : 26 JUN 2014, DOI: 10.1111/tra.12179

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    Hsp90, an unlikely ally in the war on cancer

    The FEBS Journal

    Volume 280, Issue 6, March 2013, Pages: 1381–1396, Jared J. Barrott and Timothy A. J. Haystead

    Version of Record online : 24 FEB 2013, DOI: 10.1111/febs.12147

  10. Heat shock protein 90 maintains the stability and function of transcription factor Broad Z7 by interacting with its Broad-Complex-Tramtrack-Bric-a-brac domain

    Insect Molecular Biology

    Volume 23, Issue 6, December 2014, Pages: 720–732, M.-J. Cai, X.-R. Li, X.-Y. Pei, W. Liu, J.-X. Wang and X.-F. Zhao

    Version of Record online : 24 JUL 2014, DOI: 10.1111/imb.12118

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    Apo-Hsp90 coexists in two open conformational states in solution

    Biology of the Cell

    Volume 100, Issue 7, July 2008, Pages: 413–425, Patrick Bron, Emmanuel Giudice, Jean-Paul Rolland, Rubén M. Buey, Pascale Barbier, J. Fernando Díaz, Vincent Peyrot, Daniel Thomas and Cyrille Garnier

    Version of Record online : 9 JAN 2012, DOI: 10.1042/BC20070149

  12. Discovery and Bioevaluation of Novel Pyrazolopyrimidine Analogs as Competitive Hsp90 Inhibitors Through Shape-Based Similarity Screening

    Molecular Informatics

    Volume 33, Issue 4, April 2014, Pages: 293–306, Xiao-Li Xu, Hao-Peng Sun, Fang Liu, Jian-Min Jia, Xiao-Ke Guo, Yang Pan, Hao-Ze Huang, Xiao-Jin Zhang and Qi-Dong You

    Version of Record online : 11 APR 2014, DOI: 10.1002/minf.201300150

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    Molecular analysis of common wheat genes encoding three types of cytosolic heat shock protein 90 (Hsp90): functional involvement of cytosolic Hsp90s in the control of wheat seedling growth and disease resistance

    New Phytologist

    Volume 191, Issue 2, July 2011, Pages: 418–431, Guan-Feng Wang, Xuening Wei, Renchun Fan, Huanbin Zhou, Xianping Wang, Chunmei Yu, Lingli Dong, Zhenying Dong, Xiaojie Wang, Zhensheng Kang, Hongqing Ling, Qian-Hua Shen, Daowen Wang and Xiangqi Zhang

    Version of Record online : 13 APR 2011, DOI: 10.1111/j.1469-8137.2011.03715.x

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    Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23

    The EMBO Journal

    Volume 19, Issue 21, November 1, 2000, Pages: 5930–5940, Jason C. Young and F. Ulrich Hartl

    Version of Record online : 1 NOV 2000, DOI: 10.1093/emboj/19.21.5930

  15. Computational Studies of Allosteric Regulation in the Hsp90 Molecular Chaperone: From Functional Dynamics and Protein Structure Networks to Allosteric Communications and Targeted Anti-Cancer Modulators

    Israel Journal of Chemistry

    Volume 54, Issue 8-9, August 2014, Pages: 1052–1064, Gennady M. Verkhivker

    Version of Record online : 19 FEB 2014, DOI: 10.1002/ijch.201300143

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    Identification of Citrullinated Hsp90 Isoforms as Novel Autoantigens in Rheumatoid Arthritis–Associated Interstitial Lung Disease

    Arthritis & Rheumatism

    Volume 65, Issue 4, April 2013, Pages: 869–879, Lisa Harlow, Ivan O. Rosas, Bernadette R. Gochuico, Ted R. Mikuls, Paul F. Dellaripa, Chester V. Oddis and Dana P. Ascherman

    Version of Record online : 28 MAR 2013, DOI: 10.1002/art.37881

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    Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE

    European Journal of Immunology

    Volume 45, Issue 7, July 2015, Pages: 2028–2041, Keita Saito, Kazuharu Kukita, Goro Kutomi, Koichi Okuya, Hiroko Asanuma, Tetsuya Tabeya, Yasuka Naishiro, Motohisa Yamamoto, Hiroki Takahashi, Toshihiko Torigoe, Akira Nakai, Yasuhisa Shinomura, Koichi Hirata, Noriyuki Sato and Yasuaki Tamura

    Version of Record online : 28 APR 2015, DOI: 10.1002/eji.201445293

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    Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

    Cellular Microbiology

    Volume 14, Issue 3, March 2012, Pages: 368–385, Paolo Montanari, Giuseppe Bozza, Barbara Capecchi, Elena Caproni, Riccardo Barrile, Nathalie Norais, Mirco Capitani, Michele Sallese, Paola Cecchini, Laura Ciucchi, Zhenai Gao, Rino Rappuoli, Mariagrazia Pizza, Beatrice Aricò and Marcello Merola

    Version of Record online : 8 DEC 2011, DOI: 10.1111/j.1462-5822.2011.01722.x

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    Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    The EMBO Journal

    Volume 23, Issue 3, February 11, 2004, Pages: 511–519, Philippe Meyer, Chrisostomos Prodromou, Chunyan Liao, Bin Hu, S Mark Roe, Cara K Vaughan, Ignacija Vlasic, Barry Panaretou, Peter W Piper and Laurence H Pearl

    Version of Record online : 22 JAN 2004, DOI: 10.1038/sj.emboj.7600060

    Corrected by:

    Erratum: Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

    Vol. 23, Issue 6, 1402–1410, Version of Record online: 24 MAR 2004

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    Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo

    International Journal of Cancer

    Volume 132, Issue 3, 1 February 2013, Pages: 695–706, Sayantani Sarkar, Devawati Dutta, Suman Kumar Samanta, Kaushik Bhattacharya, Bikas Chandra Pal, Jinping Li, Kaustubh Datta, Chhabinath Mandal and Chitra Mandal

    Version of Record online : 9 JUL 2012, DOI: 10.1002/ijc.27687