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There are 31886 results for: content related to: Sensitive, preclinical detection of prions in brain by nanospray liquid chromatography/tandem mass spectrometry

  1. Prions of Humans and Animals

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    Topley and Wilson's Microbiology and Microbial Infections

    Adriano Aguzzi

    Published Online : 15 MAR 2010, DOI: 10.1002/9780470688618.taw0267

  2. Prions

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    Reviews in Cell Biology and Molecular Medicine

    Vincent Béringue

    Published Online : 28 APR 2015, DOI: 10.1002/3527600906.mcb.200400151.pub2

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    Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity

    Journal of Neurochemistry

    Volume 84, Issue 1, January 2003, Pages: 10–22, Yaping Gu, Susamma Verghese, Ravi Shankar Mishra, Xeumin Xu, Yongchang Shi and Neena Singh

    Article first published online : 13 DEC 2002, DOI: 10.1046/j.1471-4159.2003.01255.x

  4. Biochemistry and Structural Biology of Mammalian Prion Disease

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    Protein Science Encyclopedia

    Rudi Glockshuber

    Published Online : 15 MAR 2008, DOI: 10.1002/9783527610754.md07

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    Aggregation of cellular prion protein is initiated by proximity-induced dimerization

    Journal of Neurochemistry

    Volume 102, Issue 4, August 2007, Pages: 1195–1205, Kevin Goggin, Cyntia Bissonnette, Catherine Grenier, Leonid Volkov and Xavier Roucou

    Article first published online : 29 MAR 2007, DOI: 10.1111/j.1471-4159.2007.04611.x

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    Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

    EMBO Molecular Medicine

    Volume 7, Issue 3, March 2015, Pages: 339–356, Agnes Lau, Alex McDonald, Nathalie Daude, Charles E Mays, Eric D Walter, Robin Aglietti, Robert CC Mercer, Serene Wohlgemuth, Jacques van der Merwe, Jing Yang, Hristina Gapeshina, Chae Kim, Jennifer Grams, Beipei Shi, Holger Wille, Aru Balachandran, Gerold Schmitt-Ulms, Jiri G Safar, Glenn L Millhauser and David Westaway

    Article first published online : 6 FEB 2015, DOI: 10.15252/emmm.201404588

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    Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105–125

    The EMBO Journal

    Volume 26, Issue 2, January 24, 2007, Pages: 548–558, Aimin Li, Heather M Christensen, Leanne R Stewart, Kevin A Roth, Roberto Chiesa and David A Harris

    Article first published online : 24 JAN 2007, DOI: 10.1038/sj.emboj.7601507

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    Epitope scanning reveals gain and loss of strain specific antibody binding epitopes associated with the conversion of normal cellular prion to scrapie prion

    Journal of Neurochemistry

    Volume 90, Issue 5, September 2004, Pages: 1205–1217, Tao Pan, Ruliang Li, Shin-Cheng Kang, Boon-Seng Wong, Thomas Wisniewski and Man-Sun Sy

    Article first published online : 20 JUL 2004, DOI: 10.1111/j.1471-4159.2004.02582.x

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    Recognition of Lumenal Prion Protein Aggregates by Post-ER Quality Control Mechanisms Is Mediated by the Preoctarepeat Region of PrP

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    Volume 5, Issue 4, April 2004, Pages: 300–313, Sabine Gilch, Max Nunziante, Alexa Ertmer, Franziska Wopfner, Lajos Laszlo and Hermann M. Schätzl

    Article first published online : 18 MAR 2004, DOI: 10.1111/j.1600-0854.2004.0175.x

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    Inhibition of Complex Glycosylation Increases the Formation of PrPsc

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    Volume 4, Issue 5, May 2003, Pages: 313–322, Konstanze F. Winklhofer, Ulrich Heller, Anja Reintjes and Jörg Tatzelt

    Article first published online : 25 APR 2003, DOI: 10.1034/j.1600-0854.2003.00088.x

  11. Emerging therapeutic agents for transmissible spongiform encephalopathies: a review

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 26, Issue 5, October 2003, Pages: 315–326, T. Koster, K. Singh, M. Zimmermann and E. Gruys

    Article first published online : 20 OCT 2003, DOI: 10.1046/j.1365-2885.2003.00525.x

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    A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

    Journal of Neurochemistry

    Volume 108, Issue 1, January 2009, Pages: 44–56, Heather M. Christensen and David A. Harris

    Article first published online : 10 OCT 2008, DOI: 10.1111/j.1471-4159.2008.05719.x

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    Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion

    Journal of Neurochemistry

    Volume 104, Issue 5, March 2008, Pages: 1293–1308, Emiliano Biasini, Andrea Z. Medrano, Stefano Thellung, Roberto Chiesa and David A. Harris

    Article first published online : 20 OCT 2007, DOI: 10.1111/j.1471-4159.2007.05082.x

  14. Clearance and prevention of prion infection in cell culture by anti-PrP antibodies

    European Journal of Neuroscience

    Volume 23, Issue 10, May 2006, Pages: 2635–2647, Joanna Pankiewicz, Frances Prelli, Man-Sun Sy, Richard J. Kascsak, Regina B. Kascsak, Daryl S. Spinner, Richard I. Carp, Harry C. Meeker, Marcin Sadowski and Thomas Wisniewski

    Article first published online : 31 MAY 2006, DOI: 10.1111/j.1460-9568.2006.04805.x

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    The Novel Sorting Nexin SNX33 Interferes with Cellular PrPSc Formation by Modulation of PrPc Shedding

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    Volume 9, Issue 7, July 2008, Pages: 1116–1129, Andreas Heiseke, Susanne Schöbel, Stefan F. Lichtenthaler, Ina Vorberg, Martin H. Groschup, Hans Kretzschmar, Hermann M. Schätzl and Max Nunziante

    Article first published online : 28 JUN 2008, DOI: 10.1111/j.1600-0854.2008.00750.x

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    Stress-protective signalling of prion protein is corrupted by scrapie prions

    The EMBO Journal

    Volume 27, Issue 14, July 23, 2008, Pages: 1974–1984, Angelika S Rambold, Veronika Müller, Uri Ron, Nir Ben-Tal, Konstanze F Winklhofer and Jörg Tatzelt

    Article first published online : 19 JUN 2008, DOI: 10.1038/emboj.2008.122

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    The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

    The EMBO Journal

    Volume 30, Issue 10, May 18, 2011, Pages: 2057–2070, Ulrike K Resenberger, Anja Harmeier, Andreas C Woerner, Jessica L Goodman, Veronika Müller, Rajaraman Krishnan, R Martin Vabulas, Hans A Kretzschmar, Susan Lindquist, F Ulrich Hartl, Gerd Multhaup, Konstanze F Winklhofer and Jörg Tatzelt

    Article first published online : 25 MAR 2011, DOI: 10.1038/emboj.2011.86

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    Prion protein glycosylation

    Journal of Neurochemistry

    Volume 93, Issue 4, May 2005, Pages: 793–801, Victoria A. Lawson, Steven J. Collins, Colin L. Masters and Andrew F. Hill

    Article first published online : 20 APR 2005, DOI: 10.1111/j.1471-4159.2005.03104.x

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    Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

    The EMBO Journal

    Volume 18, Issue 12, June 15, 1999, Pages: 3193–3203, Motohiro Horiuchi and Byron Caughey

    Article first published online : 15 JUN 1999, DOI: 10.1093/emboj/18.12.3193

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    Synthetic fibril peptide promotes clearance of scrapie prion protein by lysosomal degradation

    Microbiology and Immunology

    Volume 52, Issue 7, July 2008, Pages: 357–365, Yuko Okemoto-Nakamura, Yoshio Yamakawa, Kentaro Hanada, Keiko Tanaka, Masami Miura, Isei Tanida, Masahiro Nishijima and Ken'ichi Hagiwara

    Article first published online : 8 JUL 2008, DOI: 10.1111/j.1348-0421.2008.00046.x