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There are 64231 results for: content related to: Accelerator mass spectrometry offers new opportunities for microdosing of peptide and protein pharmaceuticals

  1. Bioanalytics for Human Microdosing

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    Encyclopedia of Drug Metabolism and Interactions

    Bruce A. Buchholz, Miranda J. Sarachine Falso, Benjamin J. Stewart, Kurt W. Haack, Ted J. Ognibene, Graham Bench, Gary A. Salazar Quintero, Michael A. Malfatti, Kristen S. Kulp and Kenneth W. Turteltaub

    Published Online : 15 MAY 2012, DOI: 10.1002/9780470921920.edm112

  2. Accelerator Mass Spectrometry and Positron Emission Tomography in Human Microdosing

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    Pharmaceutical Sciences Encyclopedia

    Zhengdong Cheng

    Published Online : 16 DEC 2011, DOI: 10.1002/9780470571224.pse429

  3. Accelerator Mass Spectrometry Measurement of Intracellular Concentrations of Active Drug Metabolites in Human Target Cells In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 6, December 2010, Pages: 796–800, J Chen, R C Garner, L S Lee, M Seymour, E J Fuchs, W C Hubbard, T L Parsons, G E Pakes, C V Fletcher and C Flexner

    Version of Record online : 27 OCT 2010, DOI: 10.1038/clpt.2010.188

  4. You have free access to this content
    Accelerator mass spectrometry

    Mass Spectrometry Reviews

    Volume 27, Issue 5, September/October 2008, Pages: 398–427, Ragnar Hellborg and Göran Skog

    Version of Record online : 9 MAY 2008, DOI: 10.1002/mas.20172

  5. Accelerator Mass Spectrometry and its Applications

    Standard Article

    Encyclopedia of Applied Physics

    Ragnar Hellborg, Göran Skog and Kristina Stenström

    Published Online : 7 NOV 2014, DOI: 10.1002/3527600434.eap718

  6. Microdose Study of 14C-Acetaminophen With Accelerator Mass Spectrometry to Examine Pharmacokinetics of Parent Drug and Metabolites in Healthy Subjects

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 6, December 2010, Pages: 824–830, Z Tozuka, H Kusuhara, K Nozawa, Y Hamabe, I Ikushima, T Ikeda and Y Sugiyama

    Version of Record online : 3 NOV 2010, DOI: 10.1038/clpt.2010.206

  7. Applications of accelerator mass spectrometry for pharmacological and toxicological research

    Mass Spectrometry Reviews

    Volume 25, Issue 1, January/February 2006, Pages: 127–145, Karen Brown, Elaine M. Tompkins and Ian N.H. White

    Version of Record online : 29 JUL 2005, DOI: 10.1002/mas.20059

  8. Mass spectrometry with accelerators

    Mass Spectrometry Reviews

    Volume 30, Issue 6, November/December 2011, Pages: 1037–1072, A. E. Litherland, X-L. Zhao and W. E. Kieser

    Version of Record online : 23 DEC 2010, DOI: 10.1002/mas.20311

  9. FemtoMolar measurements using accelerator mass spectrometry

    Rapid Communications in Mass Spectrometry

    Volume 23, Issue 5, 15 March 2009, Pages: 557–563, Mehran Salehpour, Niklas Forsgard and Göran Possnert

    Version of Record online : 28 JAN 2009, DOI: 10.1002/rcm.3903

  10. Cell-surface nucleolin is involved in lipopolysaccharide internalization and signalling in alveolar macrophages

    Cell Biology International

    Volume 35, Issue 7, July 2011, Pages: 677–685, Yi Wang, Mei Mao and Jian-cheng Xu

    Version of Record online : 2 JAN 2013, DOI: 10.1042/CBI20100625

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    Accelerator mass spectrometry of small biological samples

    Rapid Communications in Mass Spectrometry

    Volume 22, Issue 23, 15 December 2008, Pages: 3928–3934, Mehran Salehpour, Niklas Forsgard and Göran Possnert

    Version of Record online : 3 NOV 2008, DOI: 10.1002/rcm.3808

  12. Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs

    Clinical Pharmacology & Therapeutics

    Volume 80, Issue 3, September 2006, Pages: 203–215, Graham Lappin, Wilhelm Kuhnz, Roeline Jochemsen, Johannes Kneer, Ajai Chaudhary, Berend Oosterhuis, Willem Jan Drijfhout, Malcolm Rowland and R. Colin Garner

    Version of Record online : 2 SEP 2006, DOI: 10.1016/j.clpt.2006.05.008

  13. Use of accelerator mass spectrometry to measure the pharmacokinetics and peripheral blood mononuclear cell concentrations of zidovudine

    Journal of Pharmaceutical Sciences

    Volume 97, Issue 7, July 2008, Pages: 2833–2843, Le T. Vuong, Jon L. Ruckle, Arlin B. Blood, Michael J. Reid, Richard D. Wasnich, Hans-Arno Synal and Stephen R. Dueker

    Version of Record online : 13 SEP 2007, DOI: 10.1002/jps.21160

  14. The Application of Accelerator Mass Spectrometry to Absolute Bioavailability Studies in Humans: Simultaneous Administration of an Intravenous Microdose of 14C-Nelfinavir Mesylate Solution and Oral Nelfinavir to Healthy Volunteers

    The Journal of Clinical Pharmacology

    Volume 45, Issue 10, October 2005, Pages: 1198–1205, Dr Nenad Sarapa, Dr Poe-Hirr Hsyu, Dr Graham Lappin and Dr Ronald Colin Garner

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270005280051

  15. Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

    Clinical Pharmacology & Therapeutics

    Volume 98, Issue 2, August 2015, Pages: 196–204, MLH Vlaming, E van Duijn, MR Dillingh, R Brands, AD Windhorst, NH Hendrikse, S Bosgra, J Burggraaf, MC de Koning, A Fidder, JAJ Mocking, H Sandman, RAF de Ligt, BO Fabriek, WJ Pasman, W Seinen, T Alves, M Carrondo, C Peixoto, PAM Peeters and WHJ Vaes

    Version of Record online : 19 MAY 2015, DOI: 10.1002/cpt.131

  16. 10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds—new analytical methods Session 8, Wednesday, June 17, 2009

    Journal of Labelled Compounds and Radiopharmaceuticals

    Volume 53, Issue 5-6, 15 - 30 May 2010, Pages: 300–314, Dean Clodfelter and Anthony Rees

    Version of Record online : 13 MAY 2010, DOI: 10.1002/jlcr.1768

  17. New Chemistries and Technologies Derived from a Common Reaction of α-Methylstyrene at 61 °C

    Macromolecular Reaction Engineering

    Volume 9, Issue 5, October 2015, Pages: 490–502, Yuhong Ma, Shan Jiang, Shujun Liang and Wantai Yang

    Version of Record online : 25 MAR 2015, DOI: 10.1002/mren.201400059

  18. Chemical and microphysical characterization of ambient aerosols with the aerodyne aerosol mass spectrometer

    Mass Spectrometry Reviews

    Volume 26, Issue 2, March/April 2007, Pages: 185–222, M.R. Canagaratna, J.T. Jayne, J.L. Jimenez, J.D. Allan, M.R. Alfarra, Q. Zhang, T.B. Onasch, F. Drewnick, H. Coe, A. Middlebrook, A. Delia, L.R. Williams, A.M. Trimborn, M.J. Northway, P.F. DeCarlo, C.E. Kolb, P. Davidovits and D.R. Worsnop

    Version of Record online : 17 JAN 2007, DOI: 10.1002/mas.20115

  19. In search for better pharmacological prophylaxis for acute mountain sickness: looking in other directions

    Acta Physiologica

    Volume 214, Issue 1, May 2015, Pages: 51–62, H. Lu, R. Wang, J. Xiong, H. Xie, B. Kayser and Z.P. Jia

    Version of Record online : 28 MAR 2015, DOI: 10.1111/apha.12490

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    Evaluating heat-related mortality in Korea by objective classifications of ‘air masses’

    International Journal of Climatology

    Volume 30, Issue 10, August 2010, Pages: 1484–1501, Jan Kyselý, Radan Huth and Jiyoung Kim

    Version of Record online : 20 AUG 2009, DOI: 10.1002/joc.1994