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There are 61719 results for: content related to: Why do we need some large, simple randomized trials?

  1. The utility of large, simple trials in the evaluation of AIDS treatment strategies

    Statistics in Medicine

    Volume 13, Issue 5-7, 15 March - 15 April 1994, Pages: 405–415, Dr. Susan S. Ellenberg and Mary A. Foulkes

    Article first published online : 15 OCT 2006, DOI: 10.1002/sim.4780130505

  2. The impact of heterogeneity on the comparison of survival times

    Statistics in Medicine

    Volume 6, Issue 7, October/November 1987, Pages: 773–784, Martin Schumacher, Manfred Olschewski and Claudia Schmoor

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060708

  3. A comparison of the power of two tests for qualitative interactions

    Statistics in Medicine

    Volume 12, Issue 13, 1993, Pages: 1239–1248, S. Piantadosi and M. H. Gail

    Article first published online : 21 APR 2011, DOI: 10.1002/sim.4780121305

  4. The case of gissi in changing the attitudes and practice of Italian cardiologists

    Statistics in Medicine

    Volume 9, Issue 1-2, January - February 1990, Pages: 17–27, Gianni Tognoni, Maria Grazia Franzosi, Silvio Garattini, Aldo Maggioni, Antonio Lotto, Francesco Mauri and Fausto Rovelli

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780090108

  5. The clinical importance of early stopping of randomized trials in cancer treatments

    Statistics in Medicine

    Volume 13, Issue 13-14, 15 - 30 July 1994, Pages: 1293–1295, Robert L. Souhami

    Article first published online : 15 OCT 2006, DOI: 10.1002/sim.4780131303

  6. Statistics in medical journals: Developments in the 1980s

    Statistics in Medicine

    Volume 10, Issue 12, December 1991, Pages: 1897–1913, Douglas G. Altman

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780101206

  7. Small clinical trials: Are they all bad?

    Statistics in Medicine

    Volume 14, Issue 2, 30 January 1995, Pages: 115–126, John N. S. Matthews

    Article first published online : 28 FEB 2007, DOI: 10.1002/sim.4780140204

  8. Why do we need systematic overviews of randomized trials? (Transcript of an oral presentation, modified by the editors)

    Statistics in Medicine

    Volume 6, Issue 3, April/May 1987, Pages: 233–240, Richard Peto

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060306

  9. Problems induced by meta-analyses

    Statistics in Medicine

    Volume 10, Issue 6, June 1991, Pages: 971–980, Thomas C. Chalmers

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780100618

  10. Must clinical trials be large? The interpretation of p-values and the combination of test results

    Statistics in Medicine

    Volume 9, Issue 6, June 1990, Pages: 601–614, G. A. Barnard

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780090606

  11. Avoidance of large biases and large random errors in the assessment of moderate treatment effects: The need for systematic overviews

    Statistics in Medicine

    Volume 6, Issue 3, April/May 1987, Pages: 245–250, Dr. Rory Collins, Richard Gray, Jon Godwin and Richard Peto

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060308

  12. Issues of efficiency in combining proportions of deaths from several clinical trials

    Statistics in Medicine

    Volume 6, Issue 5, July/August 1987, Pages: 565–576, Marc Buyse and Louise M. Ryan

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060505

  13. The role of overviews in cancer therapeutics

    Statistics in Medicine

    Volume 6, Issue 3, April/May 1987, Pages: 389–393, Richard Simon

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060335

  14. Assessing apparent treatment—covariate interactions in randomized clinical trials

    Statistics in Medicine

    Volume 4, Issue 3, July/September 1985, Pages: 255–263, David P. Byar

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780040304

  15. Interim analyses, stopping rules and data monitoring in clinical trials in europe

    Statistics in Medicine

    Volume 12, Issue 5-6, March 1993, Pages: 509–520, Marc Buyse

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780120517

  16. Non-parametric analysis of treatment—covariate interaction in the presence of censoring

    Statistics in Medicine

    Volume 7, Issue 12, December 1988, Pages: 1257–1266, M. Schemper

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780071206

  17. Meta-analysis of clinical trials as a scientific discipline. I: Control of bias and comparison with large co-operative trials

    Statistics in Medicine

    Volume 6, Issue 3, April/May 1987, Pages: 315–325, Thomas C. Chalmers, Howard Levin, Henry S. Sacks, Dinah Reitman, Jayne Berrier and Raguraman Nagalingam

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780060320

  18. Tests for qualitative treatment-by-centre interaction using a ‘pushback’ procedure

    Statistics in Medicine

    Volume 12, Issue 11, June 1993, Pages: 1033–1045, Joseph L. Ciminera, Joseph F. Heyse, Ha H. Nguyen and John W. Tukey

    Article first published online : 14 MAR 2007, DOI: 10.1002/sim.4780121104

  19. Exposure efficacy and change in contact rates in evaluating prophylactic HIV vaccines in the field

    Statistics in Medicine

    Volume 13, Issue 4, 28 February 1994, Pages: 357–377, M. Elizabeth Halloran, Ira M. Longini Jr., Michael J. Haber, Claudio J. Struchiner and Robert C. Brunet

    Article first published online : 15 OCT 2006, DOI: 10.1002/sim.4780130404

  20. Sample sizes for event rate equivalence trials using prior information

    Statistics in Medicine

    Volume 12, Issue 21, 15 November 1993, Pages: 2009–2023, A. Lawrence Gould

    Article first published online : 12 OCT 2006, DOI: 10.1002/sim.4780122105