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There are 15044 results for: content related to: The Transition from Stem Cell to Progenitor Spermatogonia and Male Fertility Requires the SHP2 Protein Tyrosine Phosphatase

  1. You have full text access to this OnlineOpen article
    Functions of Shp2 in cancer

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 9, September 2015, Pages: 2075–2083, Jie Zhang, Fei Zhang and Ruifang Niu

    Version of Record online : 19 JUN 2015, DOI: 10.1111/jcmm.12618

  2. You have free access to this content
    Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development

    Journal of Neurochemistry

    Volume 113, Issue 1, April 2010, Pages: 200–212, Emory Kuo, Daniel K. Park, Iva D. Tzvetanova, Cindy V. Leiton, Brian S. Cho and Holly Colognato

    Version of Record online : 2 FEB 2010, DOI: 10.1111/j.1471-4159.2010.06596.x

  3. Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice

    The EMBO Journal

    Volume 34, Issue 11, 3 June 2015, Pages: 1493–1508, Linxiang Lan, Jane D Holland, Jingjing Qi, Stefanie Grosskopf, Regina Vogel, Balázs Györffy, Annika Wulf-Goldenberg and Walter Birchmeier

    Version of Record online : 3 MAR 2015, DOI: 10.15252/embj.201489004

    Corrected by:

    Corrigendum: Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice

    Vol. 34, Issue 18, 2383, Version of Record online: 14 SEP 2015

  4. Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo


    Volume 10, Issue 5, May 2015, Pages: 815–826, Dr. Stefanie Grosskopf, Chris Eckert, Dr. Christoph Arkona, Dr. Silke Radetzki, Dr. Kerstin Böhm, Prof. Dr. Udo Heinemann, Prof. Dr. Gerhard Wolber, Dr. Jens-Peter von Kries, Prof. Dr. Walter Birchmeier and Prof. Dr. Jörg Rademann

    Version of Record online : 15 APR 2015, DOI: 10.1002/cmdc.201500015

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    Force-dependent integrin–cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2

    The EMBO Journal

    Volume 22, Issue 19, October 1, 2003, Pages: 5023–5035, Götz von Wichert, Beatrice Haimovich, Gen-Sheng Feng and Michael P. Sheetz

    Version of Record online : 1 OCT 2003, DOI: 10.1093/emboj/cdg492

  6. SHP2 is up-regulated in breast cancer cells and in infiltrating ductal carcinoma of the breast, implying its involvement in breast oncogenesis


    Volume 53, Issue 4, October 2008, Pages: 389–402, X Zhou, J Coad, B Ducatman and Y M Agazie

    Version of Record online : 16 JUL 2008, DOI: 10.1111/j.1365-2559.2008.03103.x

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    Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice


    Volume 67, Issue 12, December 2012, Pages: 1547–1556, X.-J. Qin, G.-S. Zhang, X. Zhang, Z.-W. Qiu, P.-L. Wang, Y.-W. Li, W. Li, Q.-M. Xie, Y.-H. Ke, J. J Lee and H.-H. Shen

    Version of Record online : 11 OCT 2012, DOI: 10.1111/all.12048

  8. Direct Chemical Activation of a Rationally Engineered Signaling Enzyme


    Volume 16, Issue 12, August 17, 2015, Pages: 1735–1739, Cynthia M. Chio, Karen W. Cheng and Prof. Anthony C. Bishop

    Version of Record online : 30 JUN 2015, DOI: 10.1002/cbic.201500245

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    Brain-Derived Neurotrophic Factor Stimulates Interactions of Shp2 with Phosphatidylinositol 3-Kinase and Grb2 in Cultured Cerebral Cortical Neurons

    Journal of Neurochemistry

    Volume 73, Issue 1, July 1999, Pages: 41–49, Masashi Yamada, Hiroshi Ohnishi, Shin-ichiro Sano, Toshiyuki Araki, Atsushi Nakatani, Toshihiko Ikeuchi and Hiroshi Hatanaka

    Version of Record online : 18 JAN 2002, DOI: 10.1046/j.1471-4159.1999.0730041.x

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    The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor

    Journal of Neurochemistry

    Volume 97, Issue 3, May 2006, Pages: 834–845, John B. Easton, Amanda R. Royer and David S. Middlemas

    Version of Record online : 29 MAR 2006, DOI: 10.1111/j.1471-4159.2006.03789.x

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    Glucocorticoid suppresses BDNF-stimulated MAPK/ERK pathway via inhibiting interaction of Shp2 with TrkB

    FEBS Letters

    Volume 585, Issue 20, October 20, 2011, Pages: 3224–3228, Emi Kumamaru, Tadahiro Numakawa, Naoki Adachi and Hiroshi Kunugi

    Version of Record online : 19 SEP 2011, DOI: 10.1016/j.febslet.2011.09.010

  12. Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase


    Volume 58, Issue 12, September 2010, Pages: 1407–1414, Ying Zhu, Jinsil Park, Xuemei Hu, Kang Zheng, Hong Li, Qilin Cao, Gen-Sheng Feng and Mengsheng Qiu

    Version of Record online : 26 MAY 2010, DOI: 10.1002/glia.21016

  13. Structural mechanism associated with domain opening in gain-of-function mutations in SHP2 phosphatase

    Proteins: Structure, Function, and Bioinformatics

    Volume 79, Issue 5, May 2011, Pages: 1573–1588, Eva Darian, Olgun Guvench, Bing Yu, Cheng-Kui Qu and Alexander D. MacKerell Jr.

    Version of Record online : 1 MAR 2011, DOI: 10.1002/prot.22984

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    Targeted Disruption of Shp2 in Chondrocytes Leads to Metachondromatosis With Multiple Cartilaginous Protrusions

    Journal of Bone and Mineral Research

    Volume 29, Issue 3, March 2014, Pages: 761–769, Harry KW Kim, Gen-Sheng Feng, Di Chen, Philip D King and Nobuhiro Kamiya

    Version of Record online : 19 FEB 2014, DOI: 10.1002/jbmr.2062

  15. Src homology phosphotyrosyl phosphatase-2 expression is an independent negative prognostic factor in human breast cancer


    Volume 63, Issue 1, July 2013, Pages: 74–82, Simone Muenst, Ellen C Obermann, Feng Gao, Daniel Oertli, Carsten T Viehl, Walter P Weber, Timothy Fleming, William E Gillanders and Savas D Soysal

    Version of Record online : 15 MAY 2013, DOI: 10.1111/his.12140

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    SHP2 binds catalase and acquires a hydrogen peroxide-resistant phosphatase activity via integrin-signaling

    FEBS Letters

    Volume 577, Issue 3, November 19, 2004, Pages: 327–332, Sumio Yano, Nelly Arroyo and Noriko Yano

    Version of Record online : 14 OCT 2004, DOI: 10.1016/j.febslet.2004.10.011

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    SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells

    FEBS Letters

    Volume 584, Issue 19, October 08, 2010, Pages: 4241–4246, Young Cha and Kyung-Soon Park

    Version of Record online : 17 SEP 2010, DOI: 10.1016/j.febslet.2010.09.016

  18. SHP2-Deficiency in Chondrocytes Deforms Orofacial Cartilage and Ciliogenesis in Mice

    Journal of Bone and Mineral Research

    Volume 30, Issue 11, November 2015, Pages: 2028–2032, Nobuhiro Kamiya, Jingling Shen, Kazuo Noda, Megumi Kitami, Gen-Sheng Feng, Di Chen and Yoshihiro Komatsu

    Version of Record online : 28 JUL 2015, DOI: 10.1002/jbmr.2541

  19. A G-Quadruplex Aptamer Inhibits the Phosphatase Activity of Oncogenic Protein Shp2 in vitro


    Volume 12, Issue 3, February 11, 2011, Pages: 424–430, Jia Hu, Jie Wu, Cong Li, Ling Zhu, Dr. Wei Yun Zhang, Guiping Kong, Prof. Zhongxian Lu and Prof. Chaoyong James Yang

    Version of Record online : 10 JAN 2011, DOI: 10.1002/cbic.201000470

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    Small molecule tools for functional interrogation of protein tyrosine phosphatases

    The FEBS Journal

    Volume 280, Issue 2, January 2013, Pages: 731–750, Rongjun He, Li-Fan Zeng, Yantao He, Sheng Zhang and Zhong-Yin Zhang

    Version of Record online : 16 AUG 2012, DOI: 10.1111/j.1742-4658.2012.08718.x