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There are 10652 results for: content related to: Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells

  1. You have free access to this content
    JAK2 and genomic instability in the myeloproliferative neoplasms: A case of the chicken or the egg?

    American Journal of Hematology

    Volume 87, Issue 11, November 2012, Pages: 1028–1036, Linda M. Scott and Vivienne I. Rebel

    Version of Record online : 28 MAY 2012, DOI: 10.1002/ajh.23243

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    Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes


    Volume 33, Issue 7, July 2015, Pages: 2196–2207, Hidekazu Nishikii, Yosuke Kanazawa, Terumasa Umemoto, Yury Goltsev, Yu Matsuzaki, Kenji Matsushita, Masayuki Yamato, Garry P. Nolan, Robert Negrin and Shigeru Chiba

    Version of Record online : 27 APR 2015, DOI: 10.1002/stem.1985

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    Differential biological activity of disease-associated JAK2 mutants

    FEBS Letters

    Volume 585, Issue 7, April 06, 2011, Pages: 1007–1013, Haiying Zou, Dongqing Yan and Golam Mohi

    Version of Record online : 4 MAR 2011, DOI: 10.1016/j.febslet.2011.02.032

  4. Overview of Transgenic Mouse Models of Myeloproliferative Neoplasms (MPNs)


    Current Protocols in Pharmacology


    Andrew Dunbar, Abbas Nazir and Ross Levine

    Published Online : 22 JUN 2017, DOI: 10.1002/cpph.23

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    Differential Sensitivity to JAK Inhibitory Drugs by Isogenic Human Erythroblasts and Hematopoietic Progenitors Generated from Patient-Specific Induced Pluripotent Stem Cells


    Volume 32, Issue 1, January 2014, Pages: 269–278, Zhaohui Ye, Cyndi F. Liu, Lucie Lanikova, Sarah N. Dowey, Chaoxia He, Xiaosong Huang, Robert A. Brodsky, Jerry L. Spivak, Josef T. Prchal and Linzhao Cheng

    Version of Record online : 3 JAN 2014, DOI: 10.1002/stem.1545

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    Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1


    Volume 32, Issue 9, September 2014, Pages: 2309–2323, Dong Soon Choi, Elvin Blanco, Yoo-Shin Kim, Angel A. Rodriguez, Hong Zhao, Tim Hui-Ming Huang, Chun-Liang Chen, Guangxu Jin, Melissa D. Landis, Lacey A. Burey, Wei Qian, Sergio M. Granados, Bhuvanesh Dave, Helen H. Wong, Mauro Ferrari, Stephen T. C. Wong and Jenny C. Chang

    Version of Record online : 18 AUG 2014, DOI: 10.1002/stem.1746

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    Nuclear JAK2: Form and Function in Cancer

    The Anatomical Record

    Volume 294, Issue 9, September 2011, Pages: 1446–1459, Cui-Juan Qian, Jun Yao and Jian-Min Si

    Version of Record online : 1 AUG 2011, DOI: 10.1002/ar.21443

  8. You have full text access to this OnlineOpen article
    JAK2 inhibition has different therapeutic effects according to myeloproliferative neoplasm development in mice

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 11, November 2015, Pages: 2564–2574, Franck Debeurme, Catherine Lacout, Claudine Moratal, Rebecca G. Bagley, William Vainchenker, Francisco Adrian and Jean-Luc Villeval

    Version of Record online : 14 JUL 2015, DOI: 10.1111/jcmm.12608

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    JAK2 V617F uses distinct signalling pathways to induce cell proliferation and neutrophil activation

    British Journal of Haematology

    Volume 150, Issue 3, August 2010, Pages: 334–344, Seido Oku, Katsuto Takenaka, Takuro Kuriyama, Kotaro Shide, Takashi Kumano, Yoshikane Kikushige, Shingo Urata, Takuji Yamauchi, Chika Iwamoto, Haruko K. Shimoda, Toshihiro Miyamoto, Koji Nagafuji, Junji Kishimoto, Kazuya Shimoda and Koichi Akashi

    Version of Record online : 10 JUN 2010, DOI: 10.1111/j.1365-2141.2010.08249.x

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    P-Selectin Sustains Extramedullary Hematopoiesis in the Gata1low Model of Myelofibrosis


    Volume 34, Issue 1, January 2016, Pages: 67–82, Gerald J. Spangrude, Daniel Lewandowski, Fabrizio Martelli, Manuela Marra, Maria Zingariello, Laura Sancillo, Rosa Alba Rana and Anna Rita Migliaccio

    Version of Record online : 23 OCT 2015, DOI: 10.1002/stem.2229

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    The JAK kinase inhibitor CP-690,550 supresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation

    Cancer Science

    Volume 99, Issue 6, June 2008, Pages: 1265–1273, Taghi Manshouri, Alfonso Quintás-Cardama, Roberto H. Nussenzveig, Amos Gaikwad, Zeev Estrov, Josef Prchal, Jorge E. Cortes, Hagop M. Kantarjian and Srdan Verstovsek

    Version of Record online : 28 JUN 2008, DOI: 10.1111/j.1349-7006.2008.00817.x

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    Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

    The EMBO Journal

    Volume 17, Issue 18, September 15, 1998, Pages: 5321–5333, Juerg Schwaller, Julie Frantsve, Jon Aster, Ifor R. Williams, Michael H. Tomasson, Theodora S. Ross, Pieter Peeters, Luc Van Rompaey, Richard A. Van Etten, Robert Ilaria Jr, Peter Marynen and D.Gary Gilliland

    Version of Record online : 15 SEP 1998, DOI: 10.1093/emboj/17.18.5321

  13. BCR–JAK2 drives a myeloproliferative neoplasm in transplanted mice

    The Journal of Pathology

    Volume 236, Issue 2, June 2015, Pages: 219–228, Álvaro Cuesta-Domínguez, Diego León-Rico, Lara Álvarez, Begoña Díez, Irene Bodega-Mayor, Rocío Baños, Miguel Ángel Martín-Rey, Matilde Santos-Roncero, María Luisa Gaspar, Paloma Martín-Acosta, Elena Almarza, Juan A. Bueren, Paula Río and Elena Fernández-Ruiz

    Version of Record online : 3 MAR 2015, DOI: 10.1002/path.4513

  14. JAK2 mediates the acute response to decreased cell volume in mouse preimplantation embryos by activating NHE1

    Journal of Cellular Physiology

    Volume 228, Issue 2, February 2013, Pages: 428–438, Chenxi Zhou and Jay M. Baltz

    Version of Record online : 25 OCT 2012, DOI: 10.1002/jcp.24147

  15. Molecular Events in Growth Hormone–Receptor Interaction and Signaling

    Standard Article

    Comprehensive Physiology

    Lisa S. Smit, Debra J. Meyer, Lawrence S. Argetsinger, Jessica Schwartz and Christin Carter-Su

    Published Online : 1 JAN 2011, DOI: 10.1002/cphy.cp070514

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    Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial–mesenchymal transition

    Cancer Science

    Volume 99, Issue 2, February 2008, Pages: 272–279, Ahmed S. Sultan, Hassan Brim and Zaki A. Sherif

    Version of Record online : 6 FEB 2008, DOI: 10.1111/j.1349-7006.2007.00685.x

  17. Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells

    Journal of Cellular Biochemistry

    Volume 96, Issue 2, 1 October 2005, Pages: 361–375, Huei-Mei Huang, Yi-Li Lin, Cheng-Hsien Chen and Ting-Wei Chang

    Version of Record online : 29 JUN 2005, DOI: 10.1002/jcb.20513

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    JAK2-V617F-mediated signalling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth

    British Journal of Haematology

    Volume 160, Issue 2, January 2013, Pages: 177–187, Lori N. Griner, Kathy L. McGraw, Joseph O. Johnson, Alan F. List and Gary W. Reuther

    Version of Record online : 15 NOV 2012, DOI: 10.1111/bjh.12103

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    A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses

    British Journal of Haematology

    Volume 147, Issue 4, November 2009, Pages: 450–458, Yvonne Suessmuth, Joanne Elliott, Melanie J. Percy, Mitsuharu Inami, Hila Attal, Claire N. Harrison, Koiti Inokuchi, Mary-Frances McMullin and James A. Johnston

    Version of Record online : 7 SEP 2009, DOI: 10.1111/j.1365-2141.2009.07860.x

  20. You have full text access to this OnlineOpen article
    Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors

    Journal of Cellular and Molecular Medicine

    Volume 17, Issue 11, November 2013, Pages: 1397–1409, Meng Ling Choong, Christian Pecquet, Vishal Pendharkar, Carmen C. Diaconu, Jacklyn Wei Yan Yong, Shi Jing Tai, Si Fang Wang, Jean-Philippe Defour, Kanda Sangthongpitag, Jean-Luc Villeval, William Vainchenker, Stefan N. Constantinescu and May Ann Lee

    Version of Record online : 19 NOV 2013, DOI: 10.1111/jcmm.12156