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There are 6810 results for: content related to: Antitumor effects with apoptotic death in human promyelocytic leukemia HL-60 cells and suppression of leukemia xenograft tumor growth by irinotecan HCl

  1. You have full text access to this Open Access content
    Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma

    Cancer Science

    Volume 99, Issue 11, November 2008, Pages: 2309–2314, Hiroki Yano, Satoshi Kayukawa, Shinsuke Iida, Chiharu Nakagawa, Tetsuya Oguri, Takaomi Sanda, Jianming Ding, Fumiko Mori, Asahi Ito, Masaki Ri, Atsushi Inagaki, Shigeru Kusumoto, Takashi Ishida, Hirokazu Komatsu, Hiroshi Inagaki, Atsushi Suzuki and Ryuzo Ueda

    Article first published online : 1 SEP 2008, DOI: 10.1111/j.1349-7006.2008.00936.x

  2. You have full text access to this Open Access content
    Effective Irinotecan (CPT-11)-containing Liposomes: Intraliposomal Conversion to the Active Metabolite SN-38

    Japanese Journal of Cancer Research

    Volume 90, Issue 2, February 1999, Pages: 226–232, Yasuyuki Sadzuka, Sachiyo Hirotsu and Sadao Hirota

    Article first published online : 23 AUG 2005, DOI: 10.1111/j.1349-7006.1999.tb00737.x

  3. Effect of poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide) micelles on pharmacokinetics and intestinal toxicity of irinotecan hydrochloride: potential involvement of breast cancer resistance protein (ABCG2)

    Journal of Pharmacy and Pharmacology

    Volume 62, Issue 8, August 2010, Pages: 973–984, Shiyan Guo, Xinxin Zhang, Li Gan, Chunliu Zhu and Yong Gan

    Article first published online : 21 JUL 2010, DOI: 10.1111/j.2042-7158.2010.01128.x

  4. Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats

    Journal of Pharmacy and Pharmacology

    Volume 65, Issue 2, February 2013, Pages: 280–291, Tomoharu Yokooji, Yoshihiro Kawabe, Nobuhiro Mori and Teruo Murakami

    Article first published online : 21 SEP 2012, DOI: 10.1111/j.2042-7158.2012.01592.x

  5. Camptothecin and Its Analogs

    Annals of the New York Academy of Sciences

    Volume 803, Issue 1, December 1996, Pages: 213–223, FRANCO M. MUGGIA, ISAIAH DIMERY and SUSAN G. ARBUCK

    Article first published online : 17 DEC 2006, DOI: 10.1111/j.1749-6632.1996.tb26391.x

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    Dual functional octreotide-modified liposomal irinotecan leads to high therapeutic efficacy for medullary thyroid carcinoma xenografts

    Cancer Science

    Volume 103, Issue 2, February 2012, Pages: 310–316, Yuko Iwase and Yoshie Maitani

    Article first published online : 22 NOV 2011, DOI: 10.1111/j.1349-7006.2011.02128.x

  7. You have free access to this content
    Cellular effects of CPT-11 on colon carcinoma cells: Dependence on p53 and hMLH1 status

    International Journal of Cancer

    Volume 101, Issue 1, 1 September 2002, Pages: 23–31, Roberta Magrini, Mandar R. Bhonde, Marie-Luise Hanski, Michael Notter, Hans Scherübl, C. Richard Boland, Martin Zeitz and Christoph Hanski

    Article first published online : 19 JUL 2002, DOI: 10.1002/ijc.10565

  8. Interaction of interferon gamma and CPT-11, a new derivative of camptothecin, in human endometrial carcinoma cell lines

    International Journal of Gynecological Cancer

    Volume 3, Issue 1, January/February 1993, Pages: 36–43, H. Mori, M. Sawairi, K. Niwa, N. Itoh, T. Hanabayashi, H. Kondoh and T. Tamaya

    Article first published online : 24 FEB 2002, DOI: 10.1046/j.1525-1438.1993.03010036.x

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    Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib (“Iressa”) and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells

    International Journal of Cancer

    Volume 108, Issue 3, 20 January 2004, Pages: 464–472, Fumiaki Koizumi, Fumihiko Kanzawa, Yutaka Ueda, Yasuhiro Koh, Shoji Tsukiyama, Fumiko Taguchi, Tomohide Tamura, Nagahiro Saijo and Kazuto Nishio

    Article first published online : 21 OCT 2003, DOI: 10.1002/ijc.11539

  10. Effects of CPT-11 in combination with other anti-cancer agents in culture

    International Journal of Cancer

    Volume 50, Issue 4, 20 February 1992, Pages: 604–610, Yasuhiko Kano, Kenichi Suzuki, Miyuki Akutsu, Keiichi Suda, Yoshiharu Indue, Minoru Yosnida, Shinobu Sakamoto and Yasusada Miura

    Article first published online : 17 JUL 2006, DOI: 10.1002/ijc.2910500420

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    Overcoming CPT-11 resistance by using a biscoclaurine alkaloid, cepharanthine, to modulate plasma trans-membrane potential

    International Journal of Cancer

    Volume 72, Issue 2, 17 July 1997, Pages: 295–300, Kenjiro Aogi, Masahiko Nishiyama, Ryungsa Kim, Naoki Hirabayashi, Tetsuya Toge, Akiko Mizutani, Kosuke Okada, Hidetaka Sumiyoshi, Yasuhiro Fujiwara, Michio Yamakido, Toshihisa Kusano and Toshiwo Andoh

    Article first published online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-0215(19970717)72:2<295::AID-IJC16>3.0.CO;2-F

  12. Experimental studies on biochemical modulation targeting topoisomerase I and II in human tumor xenografts in nude mice

    International Journal of Cancer

    Volume 50, Issue 5, 12 March 1992, Pages: 760–766, Ryungsa Kim, Naoki Hirabayashi, Masahiko Nishiyama, Kazuto Jinushi, Tetsuya Toge and Kosuke Okada

    Article first published online : 17 JUL 2006, DOI: 10.1002/ijc.2910500516

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    Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma

    International Journal of Cancer

    Volume 124, Issue 11, 1 June 2009, Pages: 2505–2511, Jun-ichiro Kuroda, Jun-ichi Kuratsu, Masahiro Yasunaga, Yoshikatsu Koga, Yohei Saito and Yasuhiro Matsumura

    Article first published online : 24 NOV 2008, DOI: 10.1002/ijc.24171

  14. You have full text access to this Open Access content
    Protective Effects of Kampo Medicines and Baicalin against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT-11), in Rats

    Japanese Journal of Cancer Research

    Volume 86, Issue 10, October 1995, Pages: 978–984, Kiyoshi Takasuna, Yoshio Kasai, Yutaka Kitano, Kazuhiko Mori, Reiko Kobayashi, Takehiro Hagiwara, Kohji Kakihata, Masaaki Hirohashi, Mamoru Nomura, Eiichi Nagai and Tetsuya Kamataki

    Article first published online : 24 AUG 2005, DOI: 10.1111/j.1349-7006.1995.tb03010.x

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    A phase I clinical and pharmacologic study of a carboplatin and irinotecan regimen combined with recombinant human granulocyte-colony stimulating factor in the treatment of patients with advanced nonsmall cell lung carcinoma

    Cancer

    Volume 82, Issue 11, 1 June 1998, Pages: 2166–2172, Hiroaki Okamoto, Akira Nagatomo, Hideo Kunitoh, Hiroshi Kunikane and Koshiro Watanabe

    Article first published online : 31 OCT 2000, DOI: 10.1002/(SICI)1097-0142(19980601)82:11<2166::AID-CNCR11>3.0.CO;2-S

  16. Phase I/II Pharmacokinetic and Pharmacogenomic Study of UGT1A1 Polymorphism in Elderly Patients With Advanced Non–Small Cell Lung Cancer Treated With Irinotecan

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 2, February 2009, Pages: 149–154, N Yamamoto, T Takahashi, H Kunikane, N Masuda, K Eguchi, M Shibuya, Y Takeda, H Isobe, T Ogura, A Yokoyama and K Watanabe

    Article first published online : 6 AUG 2008, DOI: 10.1038/clpt.2008.152

  17. An analytical method for irinotecan (CPT-11) and its metabolites using a high-performance liquid chromatography: parallel detection with fluorescence and mass spectrometry

    Biomedical Chromatography

    Volume 16, Issue 3, May 2002, Pages: 209–218, Kimie Sai, Naoko Kaniwa, Shogo Ozawa and Jun-ichi Sawada

    Article first published online : 19 FEB 2002, DOI: 10.1002/bmc.137

  18. You have full text access to this Open Access content
    Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenografts

    Cancer Science

    Volume 100, Issue 11, November 2009, Pages: 2193–2201, Michio Kaneko, Setsuko Kaneko and Kenshi Suzuki

    Article first published online : 8 JUL 2009, DOI: 10.1111/j.1349-7006.2009.01280.x

  19. Hypoxia-targeted over-expression of carboxylesterase as a means of increasing tumour sensitivity to irinotecan (CPT-11)

    The Journal of Gene Medicine

    Volume 9, Issue 4, April 2007, Pages: 244–252, Torkjel Matzow, Rachel L. Cowen, Kaye J. Williams, Brian A. Telfer, Pamela J. Flint, Thomas D. Southgate and Mark P. Saunders

    Article first published online : 2 APR 2007, DOI: 10.1002/jgm.1016

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    CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinants

    International Journal of Cancer

    Volume 70, Issue 3, 27 January 1997, Pages: 335–340, Willy J.M. Jansen, Bas Zwart, Saskia T.M. Hulscher, Giuseppe Giaccone, Herbert M. Pinedo and Epic Boven

    Article first published online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-0215(19970127)70:3<335::AID-IJC15>3.0.CO;2-E