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There are 32016 results for: content related to: Increased t-PA Yields Using Ultrafiltration of an Inhibitory Product from CHO Fed-Batch Culture

  1. Fed-batch CHO cell t-PA production and feed glutamine replacement to reduce ammonia production

    Biotechnology Progress

    Volume 29, Issue 1, January/February 2013, Pages: 165–175, Do Yun Kim, Muhammad Arshad Chaudhry, Malcolm L. Kennard, Mario A. Jardon, Katrin Braasch, Ben Dionne, Michael Butler and James M. Piret

    Version of Record online : 4 DEC 2012, DOI: 10.1002/btpr.1658

  2. Inhibition of glutamine-dependent autophagy increases t-PA production in CHO Cell fed-batch processes

    Biotechnology and Bioengineering

    Volume 109, Issue 5, May 2012, Pages: 1228–1238, Mario A. Jardon, Beheroze Sattha, Katrin Braasch, Amy O. Leung, Hélène C.F. Côté, Michael Butler, Sharon M. Gorski and James M. Piret

    Version of Record online : 21 DEC 2011, DOI: 10.1002/bit.24393

  3. Logistic Equations Effectively Model Mammalian Cell Batch and Fed-Batch Kinetics by Logically Constraining the Fit

    Biotechnology Progress

    Volume 21, Issue 4, 2005, Pages: 1109–1118, Chetan T. Goudar, Klaus Joeris, Konstantin B. Konstantinov and James M. Piret

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp050018j

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    A fed-batch based cultivation mode in Escherichia coli results in improved specific activity of a novel chimeric-truncated form of tissue plasminogen activator

    Journal of Applied Microbiology

    Volume 114, Issue 2, February 2013, Pages: 364–372, F. Mahboudi, F. Barkhordari, R.M. Godarzi, S. Enayati and F. Davami

    Version of Record online : 17 DEC 2012, DOI: 10.1111/jam.12059

  5. Production of tissue plasminogen activator (t-PA) in Aspergillus niger

    Biotechnology and Bioengineering

    Volume 76, Issue 2, September 2001, Pages: 164–174, Marilyn G. Wiebe, Atul Karandikar, Geoff D. Robson, Anthony P. J. Trinci, Juana-L Flores Candia, Susanne Trappe, Gregg Wallis, Ursula Rinas, Patrick M. F. Derkx, Susan M. Madrid, Heidi Sisniega, Ignacio Faus, Roy Montijn, Cees A. M. J. J. van den Hondel and Peter J. Punt

    Version of Record online : 8 AUG 2001, DOI: 10.1002/bit.1156

  6. Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator

    Biotechnology and Bioengineering

    Volume 70, Issue 1, 5 October 2000, Pages: 25–31, Dana C. Andersen, Tiffany Bridges, Martin Gawlitzek and Cynthia Hoy

    Version of Record online : 1 AUG 2000, DOI: 10.1002/1097-0290(20001005)70:1<25::AID-BIT4>3.0.CO;2-Q

  7. Cell Attachment to Microcarriers Affects Growth, Metabolic Activity, and Culture Productivity in Bioreactor Culture

    Biotechnology Progress

    Volume 23, Issue 3, 2007, Pages: 652–660, Jong Hyun Nam, Myriam Ermonval and Susan T. Sharfstein

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp070007l

  8. Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture

    Biotechnology and Bioengineering

    Volume 110, Issue 7, July 2013, Pages: 2013–2024, Neil Templeton, Jason Dean, Pranhitha Reddy and Jamey D. Young

    Version of Record online : 4 MAR 2013, DOI: 10.1002/bit.24858

  9. Cell-controlled hybrid perfusion fed-batch CHO cell process provides significant productivity improvement over conventional fed-batch cultures

    Biotechnology and Bioengineering

    Volume 114, Issue 7, July 2017, Pages: 1438–1447, Gregory W. Hiller, Ana Maria Ovalle, Matthew P. Gagnon, Meredith L. Curran and Wenge Wang

    Version of Record online : 9 FEB 2017, DOI: 10.1002/bit.26259

  10. Increase in efficiency of media utilization for recombinant protein production in Chinese hamster ovary culture through dilution

    Biotechnology and Applied Biochemistry

    Volume 58, Issue 1, January/February 2011, Pages: 25–31, Shreya Thombre and Mugdha Gadgil

    Version of Record online : 29 MAR 2011, DOI: 10.1002/bab.9

  11. Effect of Production Method and Gene Amplification on the Glycosylation Pattern of a Secreted Reporter Protein in CHO Cells

    Biotechnology Progress

    Volume 21, Issue 1, 2005, Pages: 40–49, Matthew L. Lipscomb, Laura A. Palomares, Vanessa Hernández, Octavio T. Ramírez and Dhinakar S. Kompala

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp049761m

  12. A high-yielding, generic fed-batch cell culture process for production of recombinant antibodies

    Biotechnology and Bioengineering

    Volume 67, Issue 5, 5 March 2000, Pages: 585–597, Paul W. Sauer, John E. Burky, Mark C. Wesson, Heather D. Sternard and Limin Qu

    Version of Record online : 26 MAR 2000, DOI: 10.1002/(SICI)1097-0290(20000305)67:5<585::AID-BIT9>3.0.CO;2-H

  13. Bioreactor productivity and media cost comparison for different intensified cell culture processes

    Biotechnology Progress

    Sen Xu, John Gavin, Rubin Jiang and Hao Chen

    Version of Record online : 28 JAN 2017, DOI: 10.1002/btpr.2415

  14. Limitations to the amplification and stability of human tissue-type plasminogen activator expression by Chinese hamster ovary cells

    Biotechnology and Bioengineering

    Volume 69, Issue 2, 20 July 2000, Pages: 204–212, C. H. Fann, F. Guirgis, G. Chen, M. S. Lao and J. M. Piret

    Version of Record online : 30 MAY 2000, DOI: 10.1002/(SICI)1097-0290(20000720)69:2<204::AID-BIT9>3.0.CO;2-Z

  15. High-End pH-controlled delivery of glucose effectively suppresses lactate accumulation in CHO Fed-batch cultures

    Biotechnology and Bioengineering

    Volume 108, Issue 6, June 2011, Pages: 1328–1337, Matthew Gagnon, Gregory Hiller, Yen-Tung Luan, Amy Kittredge, Jordy DeFelice and Denis Drapeau

    Version of Record online : 24 FEB 2011, DOI: 10.1002/bit.23072

  16. Glucose-based optimization of CHO-cell perfusion cultures

    Biotechnology and Bioengineering

    Volume 75, Issue 2, 20 October 2001, Pages: 252–256, Jason E. Dowd, K. Ezra Kwok and James M. Piret

    Version of Record online : 28 AUG 2001, DOI: 10.1002/bit.10013

  17. In Pursuit of the Optimal Fed-Batch Process for Monoclonal Antibody Production

    Biotechnology Progress

    Volume 11, Issue 1, January/February 1995, Pages: 1–13, Theodora A. Bibila and David K. Robinson

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp00031a001

  18. Maximization of Production of Secreted Recombinant Proteins in Pichia pastoris Fed-Batch Fermentation

    Biotechnology Progress

    Volume 21, Issue 2, 2005, Pages: 386–393, Wenhui Zhang, Jayanta Sinha, Leonard A. Smith, Mehmet Inan and Michael M. Meagher

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp049811n

  19. Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures

    Biotechnology and Bioengineering

    Volume 44, Issue 7, 20 September 1994, Pages: 808–818, Jan Ljunggren and Lene Häggström

    Version of Record online : 19 FEB 2004, DOI: 10.1002/bit.260440706

  20. Modeling and Simulation of Fed-Batch Protein Refolding Process

    Biotechnology Progress

    Volume 20, Issue 4, 2004, Pages: 1213–1219, Xiao-Yan Dong, Guang-Quan Shi, Wei Li and Yan Sun

    Version of Record online : 5 SEP 2008, DOI: 10.1021/bp0499597