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There are 12724 results for: content related to: Mfn2 modulates the UPR and mitochondrial function via repression of PERK

  1. Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

    The EMBO Journal

    Volume 35, Issue 15, 01 August 2016, Pages: 1677–1693, David Sebastián, Eleonora Sorianello, Jessica Segalés, Andrea Irazoki, Vanessa Ruiz-Bonilla, David Sala, Evarist Planet, Antoni Berenguer-Llergo, Juan Pablo Muñoz, Manuela Sánchez-Feutrie, Natàlia Plana, María Isabel Hernández-Álvarez, Antonio L Serrano, Manuel Palacín and Antonio Zorzano

    Version of Record online : 22 JUN 2016, DOI: 10.15252/embj.201593084

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    Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

    The EMBO Journal

    Volume 33, Issue 20, 16 October 2014, Pages: 2388–2407, Alejandro Martorell-Riera, Marc Segarra-Mondejar, Juan P Muñoz, Vanessa Ginet, Jordi Olloquequi, Jeús Pérez-Clausell, Manuel Palacín, Manuel Reina, Julien Puyal, Antonio Zorzano and Francesc X Soriano

    Version of Record online : 21 AUG 2014, DOI: 10.15252/embj.201488327

  3. You have full text access to this OnlineOpen article
    Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

    The EMBO Journal

    Volume 30, Issue 14, July 20, 2011, Pages: 2762–2778, Jian Zhao, Tong Liu, Shaobo Jin, Xinming Wang, Mingqi Qu, Per Uhlén, Nikolay Tomilin, Oleg Shupliakov, Urban Lendahl and Monica Nistér

    Version of Record online : 24 JUN 2011, DOI: 10.1038/emboj.2011.198

  4. You have full text access to this OnlineOpen article
    Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

    The EMBO Journal

    Volume 31, Issue 21, November 5, 2012, Pages: 4106–4123, Estela Area-Gomez, Maria del Carmen Lara Castillo, Marc D Tambini, Cristina Guardia-Laguarta, Ad J C de Groof, Moneek Madra, Junichi Ikenouchi, Masato Umeda, Thomas D Bird, Stephen L Sturley and Eric A Schon

    Version of Record online : 14 AUG 2012, DOI: 10.1038/emboj.2012.202

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    An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

    The EMBO Journal

    Volume 29, Issue 16, August 18, 2010, Pages: 2715–2723, Olga Martins de Brito and Luca Scorrano

    Version of Record online : 18 AUG 2010, DOI: 10.1038/emboj.2010.177

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    Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

    The EMBO Journal

    Volume 31, Issue 14, July 18, 2012, Pages: 3038–3062, Nicole Exner, Anne Kathrin Lutz, Christian Haass and Konstanze F Winklhofer

    Version of Record online : 26 JUN 2012, DOI: 10.1038/emboj.2012.170

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    SLP-2 is required for stress-induced mitochondrial hyperfusion

    The EMBO Journal

    Volume 28, Issue 11, June 3, 2009, Pages: 1589–1600, Daniel Tondera, Stéphanie Grandemange, Alexis Jourdain, Mariusz Karbowski, Yves Mattenberger, Sébastien Herzig, Sandrine Da Cruz, Pascaline Clerc, Ines Raschke, Carsten Merkwirth, Sarah Ehses, Frank Krause, David C Chan, Christiane Alexander, Christoph Bauer, Richard Youle, Thomas Langer and Jean-Claude Martinou

    Version of Record online : 9 APR 2009, DOI: 10.1038/emboj.2009.89

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    Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

    The EMBO Journal

    Volume 33, Issue 5, 3 March 2014, Pages: 418–436, Jakob D Wikstrom, Kiana Mahdaviani, Marc Liesa, Samuel B Sereda, Yaguang Si, Guy Las, Gilad Twig, Natasa Petrovic, Cristina Zingaretti, Adam Graham, Saverio Cinti, Barbara E Corkey, Barbara Cannon, Jan Nedergaard and Orian S Shirihai

    Version of Record online : 15 JAN 2014, DOI: 10.1002/embj.201385014

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    Shaping the role of mitochondria in the pathogenesis of Huntington's disease

    The EMBO Journal

    Volume 31, Issue 8, April 18, 2012, Pages: 1853–1864, Veronica Costa and Luca Scorrano

    Version of Record online : 23 MAR 2012, DOI: 10.1038/emboj.2012.65

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    Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 1890–1906, A R Hall, N Burke, R K Dongworth and D J Hausenloy

    Version of Record online : 28 MAR 2014, DOI: 10.1111/bph.12516

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    Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

    The EMBO Journal

    Volume 29, Issue 20, October 20, 2010, Pages: 3571–3589, Frits Kamp, Nicole Exner, Anne Kathrin Lutz, Nora Wender, Jan Hegermann, Bettina Brunner, Brigitte Nuscher, Tim Bartels, Armin Giese, Klaus Beyer, Stefan Eimer, Konstanze F Winklhofer and Christian Haass

    Version of Record online : 14 SEP 2010, DOI: 10.1038/emboj.2010.223

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    Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission

    Genes to Cells

    Volume 21, Issue 5, May 2016, Pages: 408–424, Shotaro Saita, Takaya Ishihara, Maki Maeda, Shun-ichiro Iemura, Tohru Natsume, Katsuyoshi Mihara and Naotada Ishihara

    Version of Record online : 3 MAR 2016, DOI: 10.1111/gtc.12351

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    Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

    Journal of Neurochemistry

    Volume 118, Issue 4, August 2011, Pages: 636–645, Liliane Glauser, Sarah Sonnay, Klodjan Stafa and Darren J. Moore

    Version of Record online : 6 JUN 2011, DOI: 10.1111/j.1471-4159.2011.07318.x

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    Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells

    Journal of Neurochemistry

    Volume 132, Issue 6, March 2015, Pages: 687–702, Junghyung Park, Hoonsung Choi, Ju-Sik Min, Bokyung Kim, Sang-Rae Lee, Jong Won Yun, Myung-Sook Choi, Kyu-Tae Chang and Dong-Seok Lee

    Version of Record online : 13 JAN 2015, DOI: 10.1111/jnc.12984

  15. Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model

    Journal of the Peripheral Nervous System

    Volume 19, Issue 2, June 2014, Pages: 152–164, Alleene V. Strickland, Adriana P. Rebelo, Fan Zhang, Justin Price, Brad Bolon, Jose P. Silva, Rong Wen and Stephan Züchner

    Version of Record online : 23 SEP 2014, DOI: 10.1111/jns5.12066

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    Pluripotent stem cell energy metabolism: an update

    The EMBO Journal

    Volume 34, Issue 2, 14 January 2015, Pages: 138–153, Tara Teslaa and Michael A Teitell

    Version of Record online : 4 DEC 2014, DOI: 10.15252/embj.201490446

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    MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2

    Cancer Science

    Volume 107, Issue 4, April 2016, Pages: 424–432, Xiaohu Zhou, Linshi Zhang, Bichun Zheng, Yingcai Yan, Yuan Zhang, Haiyang Xie, Lin Zhou, Shusen Zheng and Weilin Wang

    Version of Record online : 30 MAR 2016, DOI: 10.1111/cas.12904

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    Mitofusin-2 knockdown increases ER–mitochondria contact and decreases amyloid β-peptide production

    Journal of Cellular and Molecular Medicine

    Volume 20, Issue 9, September 2016, Pages: 1686–1695, Nuno Santos Leal, Bernadette Schreiner, Catarina Moreira Pinho, Riccardo Filadi, Birgitta Wiehager, Helena Karlström, Paola Pizzo and Maria Ankarcrona

    Version of Record online : 20 MAY 2016, DOI: 10.1111/jcmm.12863

  19. Physiological functions of mitochondrial fusion

    Annals of the New York Academy of Sciences

    Volume 1201, Issue 1, July 2010, Pages: 21–25, Hsiuchen Chen and David C. Chan

    Version of Record online : 21 JUL 2010, DOI: 10.1111/j.1749-6632.2010.05615.x

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    Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise

    The Journal of Physiology

    Volume 567, Issue 1, August 2005, Pages: 349–358, Romain Cartoni, Bertrand Léger, M. Benjamin Hock, Manu Praz, Antoinette Crettenand, Sara Pich, Jean-Luc Ziltener, François Luthi, Olivier Dériaz, Antonio Zorzano, Charles Gobelet, Anastasia Kralli and Aaron P. Russell

    Version of Record online : 10 AUG 2005, DOI: 10.1113/jphysiol.2005.092031