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There are 2735 results for: content related to: Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function

  1. Identifying the differences in mechanisms of mycophenolic acid controlling fucose content of glycoproteins expressed in different CHO cell lines

    Biotechnology and Bioengineering

    Volume 113, Issue 11, November 2016, Pages: 2367–2376, An Zhang, Valerie Liu Tsang, Lam R. Markely, Lutfiye Kurt, Yao-Ming Huang, Shashi Prajapati and Rashmi Kshirsagar

    Version of Record online : 11 MAY 2016, DOI: 10.1002/bit.25995

  2. Challenges with afucosylation content in antibody-based drugs: Guidance provided by mathematical modeling

    Biotechnology Progress

    Volume 31, Issue 3, May/June 2015, Pages: 775–782, Peter L. Zhan and John D. Chung

    Version of Record online : 23 FEB 2015, DOI: 10.1002/btpr.2056

  3. Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies

    Biotechnology and Bioengineering

    Volume 106, Issue 5, 1 August 2010, Pages: 751–763, Athena W. Wong, Tomasz K. Baginski and Dorothea E. Reilly

    Version of Record online : 8 APR 2010, DOI: 10.1002/bit.22749

  4. You have free access to this content
    FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality

    Biotechnology and Bioengineering

    Volume 114, Issue 3, March 2017, Pages: 632–644, Salina Louie, Benjamin Haley, Brett Marshall, Amy Heidersbach, Mandy Yim, Martina Brozynski, Danming Tang, Cynthia Lam, Bronislawa Petryniak, David Shaw, Jeongsup Shim, Aaron Miller, John B. Lowe, Brad Snedecor and Shahram Misaghi

    Version of Record online : 4 OCT 2016, DOI: 10.1002/bit.26188

  5. General solutions to decompose heterogeneous compositions using antibody afucosylation as a model system

    Biotechnology Progress

    Volume 33, Issue 2, March/April 2017, Pages: 500–510, John D. Chung and Peter L. Zhan

    Version of Record online : 10 JAN 2017, DOI: 10.1002/btpr.2428

  6. A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects


    Volume 55, Issue 6pt2, June 2015, Pages: 1501–1511, Xiaojie Yu, Melissa Menard, Gemma Seabright, Max Crispin and Alan H. Lazarus

    Version of Record online : 6 MAR 2015, DOI: 10.1111/trf.13032

  7. Tetrahydrofolate increases suspension growth of dihydrofolate reductase-deficient chinese hamster ovary DG44 cells in chemically defined media

    Biotechnology Progress

    Volume 32, Issue 6, November/December 2016, Pages: 1539–1546, Bong Gyun Kim and Hong Woo Park

    Version of Record online : 16 SEP 2016, DOI: 10.1002/btpr.2351

  8. Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals

    Biotechnology Progress

    Volume 29, Issue 2, March/April 2013, Pages: 415–424, Seshu Tummala, Michael Titus, Lee Wilson, Chunhua Wang, Carlo Ciatto, Greg Thill, Donald Foster, Chen Li, Zoltan Szabo, Andras Guttman, Brian Bettencourt, Muthuswamy Jayaraman, Jack Deroot, David Kocisko, Stuart Pollard, Klaus Charisse, Satya Kuchimanchi, Greg Hinkle, Stuart Milstein, Rachel Meyers, Shiaw-Lin Wu, Barry L. Karger and Anthony Rossomando

    Version of Record online : 13 FEB 2013, DOI: 10.1002/btpr.1667

  9. Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 6, June 2015, Pages: 1866–1884, Liming Liu

    Version of Record online : 14 APR 2015, DOI: 10.1002/jps.24444

  10. You have full text access to this OnlineOpen article
    Development of DS-5573a: A novel afucosylated mAb directed at B7-H3 with potent antitumor activity

    Cancer Science

    Volume 107, Issue 5, May 2016, Pages: 674–681, Akiko Nagase-Zembutsu, Kenji Hirotani, Michiko Yamato, Junko Yamaguchi, Takehiko Takata, Makoto Yoshida, Keisuke Fukuchi, Mitsuhiro Yazawa, Shu Takahashi and Toshinori Agatsuma

    Version of Record online : 26 APR 2016, DOI: 10.1111/cas.12915

  11. Construction of BAC-based physical map and analysis of chromosome rearrangement in chinese hamster ovary cell lines

    Biotechnology and Bioengineering

    Volume 109, Issue 6, June 2012, Pages: 1357–1367, Yihua Cao, Shuichi Kimura, Takayuki Itoi, Kohsuke Honda, Hisao Ohtake and Takeshi Omasa

    Version of Record online : 6 NOV 2011, DOI: 10.1002/bit.24347

  12. A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells

    Biotechnology Progress

    Volume 31, Issue 4, July/August 2015, Pages: 1026–1038, Zhenke Liu, Shujia Dai, Jonathan Bones, Somak Ray, Sangwon Cha, Barry L. Karger, Jingyi Jessica Li, Lee Wilson, Greg Hinckle and Anthony Rossomando

    Version of Record online : 29 APR 2015, DOI: 10.1002/btpr.2090

  13. Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-xL

    Biotechnology and Bioengineering

    Volume 101, Issue 3, 15 October 2008, Pages: 567–578, Brian S. Majors, Michael J. Betenbaugh, Nels E. Pederson and Gisela G. Chiang

    Version of Record online : 15 APR 2008, DOI: 10.1002/bit.21917

  14. Optimized selection marker and CHO host cell combinations for generating high monoclonal antibody producing cell lines

    Biotechnology Journal

    Accepted manuscript online: 25 SEP 2017, Jessna H.M. Yeo, Steven C.L. Ho, Mariati  , Esther Koh, Shi Jie Tay, Susanto Woen, Peiqing Zhang and Yuansheng Yang

    DOI: 10.1002/biot.201700175

  15. Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells

    Biotechnology and Bioengineering

    Volume 104, Issue 5, 1 December 2009, Pages: 986–994, Takeshi Omasa, Yihua Cao, Joon Young Park, Yasuhiro Takagi, Shuichi Kimura, Hidenori Yano, Kohsuke Honda, Shuichi Asakawa, Nobuyoshi Shimizu and Hisao Ohtake

    Version of Record online : 2 JUL 2009, DOI: 10.1002/bit.22463

  16. In situ cell retention of a CHO culture by a reverse-flow diafiltration membrane bioreactor

    Biotechnology Progress

    Volume 30, Issue 6, November/December 2014, Pages: 1348–1355, Kristina Meier, Suzana Djeljadini, Lars Regestein, Jochen Büchs, Frederike Carstensen, Matthias Wessling, Tanja Holland and Nicole Raven

    Version of Record online : 18 SEP 2014, DOI: 10.1002/btpr.1988

  17. You have full text access to this OnlineOpen article
    Molecular modeling of antibodies for the treatment of TNFα-related immunological diseases

    Pharmacology Research & Perspectives

    Volume 4, Issue 1, February 2016, Ciro Leonardo Pierri, Fabrizio Bossis, Giuseppe Punzi, Anna De Grassi, Michela Cetrone, Giovanni Parisi and Domenico Tricarico

    Version of Record online : 15 JAN 2016, DOI: 10.1002/prp2.197

  18. Optimized signal peptides for the development of high expressing CHO cell lines

    Biotechnology and Bioengineering

    Volume 110, Issue 4, April 2013, Pages: 1164–1173, Lars Kober, Christoph Zehe and Juergen Bode

    Version of Record online : 17 JAN 2013, DOI: 10.1002/bit.24776

  19. Development of a novel ER stress based selection system for the isolation of highly productive clones

    Biotechnology and Bioengineering

    Volume 109, Issue 10, October 2012, Pages: 2599–2611, Lars Kober, Christoph Zehe and Juergen Bode

    Version of Record online : 24 APR 2012, DOI: 10.1002/bit.24527

  20. Characterizing the effect of multiple Fc glycan attributes on the effector functions and FcγRIIIa receptor binding activity of an IgG1 antibody

    Biotechnology Progress

    Volume 32, Issue 5, September/October 2016, Pages: 1181–1192, Danielle Pace, Nathaniel Lewis, Tina Wu, Ron Gillespie, Dan Leiske, Jyoti Velayudhan, Amanda Rohrbach and Lisa Connell-Crowley

    Version of Record online : 7 JUN 2016, DOI: 10.1002/btpr.2300